KR840001509B1 - 피복된 연질 캡슈울의 제조방법 - Google Patents
피복된 연질 캡슈울의 제조방법 Download PDFInfo
- Publication number
- KR840001509B1 KR840001509B1 KR1019810001168A KR810001168A KR840001509B1 KR 840001509 B1 KR840001509 B1 KR 840001509B1 KR 1019810001168 A KR1019810001168 A KR 1019810001168A KR 810001168 A KR810001168 A KR 810001168A KR 840001509 B1 KR840001509 B1 KR 840001509B1
- Authority
- KR
- South Korea
- Prior art keywords
- carnauba wax
- soft
- wool
- soft cap
- coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 9
- 239000007901 soft capsule Substances 0.000 title claims description 7
- 235000013869 carnauba wax Nutrition 0.000 claims description 36
- 239000004203 carnauba wax Substances 0.000 claims description 36
- 238000000576 coating method Methods 0.000 claims description 22
- 239000011248 coating agent Substances 0.000 claims description 17
- 229920000159 gelatin Polymers 0.000 claims description 5
- 235000019322 gelatine Nutrition 0.000 claims description 5
- 239000011247 coating layer Substances 0.000 claims description 3
- 239000001828 Gelatine Substances 0.000 claims 2
- 210000002268 wool Anatomy 0.000 description 38
- 229940082483 carnauba wax Drugs 0.000 description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 230000000694 effects Effects 0.000 description 13
- 238000000034 method Methods 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000011521 glass Substances 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- 239000001993 wax Substances 0.000 description 4
- 108010010803 Gelatin Proteins 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000008188 pellet Substances 0.000 description 3
- 235000010919 Copernicia prunifera Nutrition 0.000 description 2
- 244000180278 Copernicia prunifera Species 0.000 description 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229940108325 retinyl palmitate Drugs 0.000 description 1
- 235000019172 retinyl palmitate Nutrition 0.000 description 1
- 239000011769 retinyl palmitate Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5998180A JPS56156212A (en) | 1980-05-08 | 1980-05-08 | Surface treating method of soft capsule agent |
| JP55-59981 | 1980-05-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR830004844A KR830004844A (ko) | 1983-07-20 |
| KR840001509B1 true KR840001509B1 (ko) | 1984-09-29 |
Family
ID=13128848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019810001168A Expired KR840001509B1 (ko) | 1980-05-08 | 1981-04-07 | 피복된 연질 캡슈울의 제조방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4350679A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0039879B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS56156212A (cg-RX-API-DMAC7.html) |
| KR (1) | KR840001509B1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE4372T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1179904A (cg-RX-API-DMAC7.html) |
| DE (1) | DE3160721D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES501992A0 (cg-RX-API-DMAC7.html) |
| PH (1) | PH16668A (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05507717A (ja) * | 1990-06-25 | 1993-11-04 | ザ・デュポン・メルク・ファーマシュウティカル・カンパニー | 軟ゼラチンカプセル剤中で使用するための高められた溶解特性を有するアマンタジン塩酸塩懸濁液 |
| US5175002A (en) * | 1991-10-02 | 1992-12-29 | Du Pont Merck Pharmaceutical Company | Amantadine hydrochloride syspension with enhanced dissolution characteristics for use in soft gelatin capsules |
| EP0613672A1 (en) * | 1993-03-01 | 1994-09-07 | Tambrands, Inc. | Water-soluble tampon applicator |
| DE69407949T2 (de) * | 1993-10-01 | 1998-05-14 | Scherer Corp R P | Zusammensetzungen zum verteilen von duftstoffen |
| US5614217A (en) * | 1995-06-07 | 1997-03-25 | R.P. Scherer Corporation | Capsule shell formulation to produce brittle capsules |
| US6004571A (en) * | 1997-09-04 | 1999-12-21 | Thies; Curt | Simulated insect eggs |
| NL1009107C2 (nl) * | 1997-11-12 | 1999-06-15 | Banner Pharmacaps Inc | Gelatine-uitspreidende doos met meervoudige, aanpasbare poortklep en meerlagig zacht gel. |
| US6193999B1 (en) | 1999-03-01 | 2001-02-27 | Banner Pharmacaps, Inc. | Gum acacia substituted soft gelatin capsules |
| EP1258242A1 (de) * | 2001-05-15 | 2002-11-20 | Swiss Caps Rechte und Lizenzen AG | Verfahren zum Herstellen von Formkörpern, insbesondere von Weichkapseln |
| US6858666B2 (en) | 2002-03-04 | 2005-02-22 | Aveka, Inc. | Organogel particles |
| PT1578350E (pt) | 2002-03-26 | 2009-08-27 | Euro Celtique Sa | Composições revestidas com geles de libertação constante |
| ATE376415T1 (de) * | 2003-01-08 | 2007-11-15 | Swiss Caps Rechte & Lizenzen | Formkörper bestehend aus gelatinfreiem material und gefüllt mit einer flüssigen füllmasse |
| US7114286B2 (en) * | 2003-06-12 | 2006-10-03 | Scott Bradford L | System for reducing the number of predator fish |
| US6886290B2 (en) * | 2003-06-12 | 2005-05-03 | Bradford L. Scott | System for reducing the number of predator fish |
| EP1721619A4 (en) | 2004-02-17 | 2012-09-05 | Eisai R&D Man Co Ltd | PREPARATION FOR FLEXIBLE CAPSULE |
| US20080044481A1 (en) * | 2004-05-27 | 2008-02-21 | Mordechai Harel | Microparticles for Oral Delivery |
| US8597709B2 (en) | 2005-04-12 | 2013-12-03 | Inovobiologic Inc. | Dietary supplement and methods of use |
| WO2006136197A1 (en) | 2005-06-21 | 2006-12-28 | V. Mane Fils | Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule |
| US20070053972A1 (en) * | 2005-09-08 | 2007-03-08 | Cadbury Adams Usa Llc. | Gelatin capsules containing actives |
| US20090169590A1 (en) * | 2007-12-26 | 2009-07-02 | Scott Bradford L | System for reducing the number of predator fish |
| US8728446B2 (en) * | 2008-06-03 | 2014-05-20 | I Did It, Inc. | Oral hygiene tablets and capsules for direct oral delivery of active ingredients |
| WO2010111347A2 (en) | 2009-03-26 | 2010-09-30 | Advanced Bionutrition Corporation | Microencapsulation of bioactive substances and methods of making the same |
| US8663671B2 (en) * | 2009-11-05 | 2014-03-04 | Philip Morris Usa Inc. | Methods and compositions for producing hydrogel capsules coated for low permeability and physical integrity |
| CN104359788A (zh) * | 2014-12-01 | 2015-02-18 | 江苏辰星海洋生物科技有限公司 | 一种测定软胶囊胶皮水分的方法 |
| GB201607548D0 (en) | 2016-04-29 | 2016-06-15 | Univ Central Lancashire | Solid dosage form |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3197369A (en) * | 1962-02-15 | 1965-07-27 | Scherer Gmbh R P | Coated gelatin capsules |
| GB461317A (en) * | 1935-08-08 | 1937-02-08 | Kelp Ol Lab Inc | Coating for medical compound |
| US2491475A (en) * | 1946-03-25 | 1949-12-20 | Parke Davis & Co | Enteric capsule |
| US2816062A (en) * | 1954-05-27 | 1957-12-10 | Univ Illinois | Hydroxyethyl cellulose tablet coating |
| DE1116867B (de) * | 1960-09-07 | 1961-11-09 | Scherer Gmbh R P | Verfahren zur Herstellung eines Rektal-Kapsel-UEberzuges |
| DE1178173B (de) * | 1961-02-17 | 1964-09-17 | Scherer Gmbh R P | Verfahren zur Herstellung eines nicht klebenden, tropenfesten UEberzuges auf Gelatine-Rektal-Kapseln |
| DE1181863B (de) * | 1963-01-05 | 1964-11-19 | Scherer Gmbh R P | Verfahren zur Herstellung eines Rektal-Kapsel-UEberzuges |
| US3456051A (en) * | 1965-10-20 | 1969-07-15 | Takeda Chemical Industries Ltd | Soft gelatin sheet for soft gelatin capsule |
| US3438797A (en) * | 1965-10-21 | 1969-04-15 | Jerry Allen Biddle Sr | Method of preparing pharmaceutical tablets |
| DE1617671C3 (de) * | 1967-03-07 | 1980-07-03 | A. Nattermann & Cie Gmbh, 5000 Koeln | Weichgelatine-Kapseln mit erhöhter Wärmestabilität |
| US3576665A (en) * | 1968-07-01 | 1971-04-27 | Merck & Co Inc | Method for applying high luster coating to tablets |
| US4138013A (en) * | 1976-08-27 | 1979-02-06 | Parke, Davis & Company | Enteric capsules |
-
1980
- 1980-05-08 JP JP5998180A patent/JPS56156212A/ja active Granted
-
1981
- 1981-04-07 KR KR1019810001168A patent/KR840001509B1/ko not_active Expired
- 1981-04-13 US US06/253,626 patent/US4350679A/en not_active Expired - Lifetime
- 1981-04-24 PH PH25550A patent/PH16668A/en unknown
- 1981-05-05 EP EP81103381A patent/EP0039879B1/en not_active Expired
- 1981-05-05 DE DE8181103381T patent/DE3160721D1/de not_active Expired
- 1981-05-05 AT AT81103381T patent/ATE4372T1/de not_active IP Right Cessation
- 1981-05-07 ES ES501992A patent/ES501992A0/es active Granted
- 1981-05-07 CA CA000377113A patent/CA1179904A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0039879A1 (en) | 1981-11-18 |
| US4350679A (en) | 1982-09-21 |
| ATE4372T1 (de) | 1983-08-15 |
| PH16668A (en) | 1983-12-13 |
| ES8206182A1 (es) | 1982-08-16 |
| DE3160721D1 (en) | 1983-09-08 |
| ES501992A0 (es) | 1982-08-16 |
| KR830004844A (ko) | 1983-07-20 |
| EP0039879B1 (en) | 1983-08-03 |
| CA1179904A (en) | 1984-12-27 |
| JPS56156212A (en) | 1981-12-02 |
| JPS6354685B2 (cg-RX-API-DMAC7.html) | 1988-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19810407 |
|
| PG1501 | Laying open of application | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19840428 Patent event code: PE09021S01D |
|
| PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19840905 |
|
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19841213 |
|
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19841222 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 19841222 End annual number: 3 Start annual number: 1 |
|
| PR1001 | Payment of annual fee |
Payment date: 19870828 Start annual number: 4 End annual number: 4 |
|
| PR1001 | Payment of annual fee |
Payment date: 19871229 Start annual number: 5 End annual number: 5 |
|
| PR1001 | Payment of annual fee |
Payment date: 19890817 Start annual number: 6 End annual number: 6 |
|
| PR1001 | Payment of annual fee |
Payment date: 19900810 Start annual number: 7 End annual number: 7 |
|
| PR1001 | Payment of annual fee |
Payment date: 19910814 Start annual number: 8 End annual number: 8 |
|
| PR1001 | Payment of annual fee |
Payment date: 19920903 Start annual number: 9 End annual number: 9 |
|
| PR1001 | Payment of annual fee |
Payment date: 19930331 Start annual number: 10 End annual number: 10 |
|
| PR1001 | Payment of annual fee |
Payment date: 19940819 Start annual number: 11 End annual number: 11 |
|
| PR1001 | Payment of annual fee |
Payment date: 19950926 Start annual number: 12 End annual number: 12 |
|
| PC1801 | Expiration of term |