KR840000903A - 키타사마이신과 퀴녹살린 디-n-옥사이드의 배합조성물 - Google Patents

키타사마이신과 퀴녹살린 디-n-옥사이드의 배합조성물 Download PDF

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Publication number
KR840000903A
KR840000903A KR1019820003845A KR820003845A KR840000903A KR 840000903 A KR840000903 A KR 840000903A KR 1019820003845 A KR1019820003845 A KR 1019820003845A KR 820003845 A KR820003845 A KR 820003845A KR 840000903 A KR840000903 A KR 840000903A
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compound
composition
optionally substituted
hydrogen
nitrogen atom
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KR1019820003845A
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KR860000275B1 (ko
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헨리 젤레 페터
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게르하르트 뷰네만, 귄테르 페터스
바이엘 아크티엔 게젤샤프트
귄테르 페터스
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Application filed by 게르하르트 뷰네만, 귄테르 페터스, 바이엘 아크티엔 게젤샤프트, 귄테르 페터스 filed Critical 게르하르트 뷰네만, 귄테르 페터스
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Feed For Specific Animals (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

내용 없음

Description

키타사마이신과 퀴녹살린 디-N-옥사이드의 배합조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 활성성분으로 (1) 카타사마이신 및 (2) 하기 일반식(Ⅰ)의 2-메틸-3-키복스아미도퀴녹살린-1,4-디-N-옥사이드 화합물만을, 또는 희석제와의 혼합물을 포함하는 약제학적 조성물.
  3. 상기식에서 R1은 수소 또는 염소원자, C1-C4알킬그룹 또는 C1-C|4알콕시그룹을 나타내고, R2는 수소원자, 또는 하이드록시, C1-C4알콕시, 카보알콕시, 모노알킬아미노 또는 디알킬아미노에 의해 임의 치환된 직쇄 또는 측쇄알킬그룹을 나타내고, R3는 R2와는 별개로 R2에 대해 정의된 어떤 의미일 수 있고, R2가 수소원자일 때는 R3는 사이클로헥실라디칼을 나타낼 수도 있으며, 또는 R2와 R3는 이들이 연결되어 있는 질소원자 및 임의의 하나의 산소 또는 또하나의 질소원자와 함께 5원 또는 6원소의 복소환을 이루며, 6원소환에 있어서 부가된 질소원자상의 수소원자는 임의로 하이드록실-, 메톡시- 또는 아세톡시 치환된 C1-C4알킬그룹에 의해 임의로 대치될 수 있다.
  4. 제1항에 있어서, 화합물(2)가 N-(2-하이드록시에틸)-3-메틸-2-퀴녹살린카복스아미드-1,4-N-디-옥사이드인 조성물.
  5. 제1항에 있어서, 화합물(2)가 제2항에 언급한 화합물이 아닌 본 명세서에서 서술된 화합물중의 어느 하나인 조성물.
  6. 제1항 내지 3항중의 어느 하나에 있어서, 화합물(1)과 화합물(2)를 1 : 10 내지 10 : 1중량부의 비율로 포함하는 조성물.
  7. 제4항에 있어서, 화합물(1)과 화합물(2)를 1 : 1의 중량비로 포함하는 조성물.
  8. 제1항에 있어서, 본 명세서에서 상세히 설명한 바와 같은 조성물.
  9. 제1항 내지 6항중의 어느 하나에 있어서, 사람을 제외한 동물의 성장촉진 및 사료이용율을 개선시킬 목적에 사용되는 조성물.
  10. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR828203845A 1981-08-27 1982-08-26 키타사마이신과 퀴녹살린 디-n-옥사이드의 배합 조성물 KR860000275B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19813133888 DE3133888A1 (de) 1981-08-27 1981-08-27 Wirkstoffkombination aus kitasamycin und chinoxalin-di-n-oxiden
DE3133888 1981-08-27
DE3133888.7 1981-08-27

Publications (2)

Publication Number Publication Date
KR840000903A true KR840000903A (ko) 1984-03-26
KR860000275B1 KR860000275B1 (ko) 1986-03-26

Family

ID=6140231

Family Applications (1)

Application Number Title Priority Date Filing Date
KR828203845A KR860000275B1 (ko) 1981-08-27 1982-08-26 키타사마이신과 퀴녹살린 디-n-옥사이드의 배합 조성물

Country Status (12)

Country Link
EP (1) EP0073390B1 (ko)
JP (1) JPS5852224A (ko)
KR (1) KR860000275B1 (ko)
AT (1) ATE20171T1 (ko)
AU (1) AU552563B2 (ko)
BR (1) BR8205020A (ko)
DE (2) DE3133888A1 (ko)
EG (1) EG15924A (ko)
ES (1) ES515272A0 (ko)
FI (1) FI70364C (ko)
PH (1) PH19663A (ko)
ZA (1) ZA826230B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3230273A1 (de) * 1982-08-14 1984-02-16 Bayer Ag, 5090 Leverkusen Lichtstabilisierte chinoxalin-di-n-oxide
DE3340931A1 (de) * 1983-11-11 1985-05-23 Bayer Ag, 5090 Leverkusen Staubfreie chinoxalin-1,4-di-n-oxide
JPH06701B2 (ja) * 1983-12-01 1994-01-05 旭化成工業株式会社 動物用組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3535309A (en) * 1967-09-01 1970-10-20 Kitasato Inst Antibiotics and their production
DE1670935C3 (de) * 1967-10-04 1975-12-04 Bayer Ag, 5090 Leverkusen 2-Methyl-3-carbonsäureamidochinoxalin-1,4-dl-N-oxide, ein Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende antibakterielle Mittel
AT281841B (de) * 1968-10-03 1970-06-10 Bayer Ag Verfahren zur herstellung von neuen 2-methyl-3-carbonsaeureamido-chinoxalindi-n-oxiden-(1,4)
SU890961A3 (ru) * 1976-01-20 1981-12-15 Циба-Гейги Аг (Фирма) Ростстимулирующее средство дл животных
US4254120A (en) * 1978-12-19 1981-03-03 Ciba-Geigy Corporation Growth promoting quinoxaline-di-N-oxide carboxamides

Also Published As

Publication number Publication date
DE3133888A1 (de) 1983-03-10
JPS5852224A (ja) 1983-03-28
AU552563B2 (en) 1986-06-05
BR8205020A (pt) 1983-06-07
ES8400014A1 (es) 1983-10-16
FI822950L (fi) 1983-02-28
KR860000275B1 (ko) 1986-03-26
EP0073390A1 (de) 1983-03-09
DE3271554D1 (en) 1986-07-10
FI70364B (fi) 1986-03-27
ES515272A0 (es) 1983-10-16
FI822950A0 (fi) 1982-08-25
EP0073390B1 (de) 1986-06-04
PH19663A (en) 1986-06-09
AU8774882A (en) 1983-03-03
ATE20171T1 (de) 1986-06-15
FI70364C (fi) 1986-09-19
EG15924A (en) 1986-12-30
ZA826230B (en) 1983-07-27

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