KR840000550A - 1-치환된 이미다조 [1, 2-a] 이미다졸의 제조방법 - Google Patents

1-치환된 이미다조 [1, 2-a] 이미다졸의 제조방법 Download PDF

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Publication number
KR840000550A
KR840000550A KR1019820002811A KR820002811A KR840000550A KR 840000550 A KR840000550 A KR 840000550A KR 1019820002811 A KR1019820002811 A KR 1019820002811A KR 820002811 A KR820002811 A KR 820002811A KR 840000550 A KR840000550 A KR 840000550A
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KR
South Korea
Prior art keywords
imidazole
preparing
substituted imidazo
compound
formula
Prior art date
Application number
KR1019820002811A
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English (en)
Inventor
스텔 외 5 헬무트
Original Assignee
페터 피어호프, 기젤라 벨만
베링거 인겔하임 케이지
기젤라 벨만
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 페터 피어호프, 기젤라 벨만, 베링거 인겔하임 케이지, 기젤라 벨만 filed Critical 페터 피어호프, 기젤라 벨만
Publication of KR840000550A publication Critical patent/KR840000550A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

내용 없음

Description

1-치환된 이미다조 [1,2-a] 이미다졸의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 일반식 (Ⅱ)의 화합물을 60 내지 180℃의 온도에서 폐환시키고, 필요시 수득한 염기를 그의 산부가염으로 전환시킴을 특징으로 하여 일반식 (Ⅰ)의 화합물 및 그의 산부가염을 제조하는 방법.
    상기식에서 R은 모노-내지 트리-치환된 페닐그룹이며, 여기에서 치환체는 동일하거나 다른 것으로, 수소, 불소, 염소 또는 브롬원자, 메틸 또는 트리플루오로메틸 그룹 중에서 선택된 것이다.
  2. 제 1 항에 있어서, 극성 또는 비극성 유기용매의 존재하에서 반응시킴이 특징인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019820002811A 1981-06-24 1982-06-23 1-치환된 이미다조 [1, 2-a] 이미다졸의 제조방법 KR840000550A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3,124,701.6 1981-06-24
DE19813124701 DE3124701A1 (de) 1981-06-24 1981-06-24 Neue l-substituierte imidazo (1,2-a)imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
KR840000550A true KR840000550A (ko) 1984-02-25

Family

ID=6135225

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019820002811A KR840000550A (ko) 1981-06-24 1982-06-23 1-치환된 이미다조 [1, 2-a] 이미다졸의 제조방법

Country Status (19)

Country Link
US (1) US4454149A (ko)
EP (1) EP0069254A1 (ko)
JP (1) JPS584783A (ko)
KR (1) KR840000550A (ko)
AU (1) AU8512682A (ko)
CS (1) CS224650B2 (ko)
DE (1) DE3124701A1 (ko)
DK (1) DK281782A (ko)
ES (1) ES513376A0 (ko)
FI (1) FI822235L (ko)
GR (1) GR76834B (ko)
HU (1) HU185181B (ko)
IL (1) IL66112A0 (ko)
NO (1) NO822075L (ko)
PL (1) PL237053A1 (ko)
PT (1) PT75108B (ko)
SU (1) SU1060113A3 (ko)
YU (1) YU135482A (ko)
ZA (1) ZA824436B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120809A (ja) * 1983-11-30 1985-06-28 Akira Kitano 脱毛防止及び、養毛、発毛用シヤンプ−

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824879A (en) * 1956-07-28 1958-02-25 Monsanto Canada Ltd Novel vinyl derivative
DE2827617A1 (de) * 1978-06-23 1980-01-10 Boehringer Sohn Ingelheim Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Also Published As

Publication number Publication date
US4454149A (en) 1984-06-12
CS224650B2 (en) 1984-01-16
JPS584783A (ja) 1983-01-11
SU1060113A3 (ru) 1983-12-07
IL66112A0 (en) 1982-09-30
ES8307810A1 (es) 1983-07-01
YU135482A (en) 1986-04-30
ZA824436B (en) 1984-02-29
HU185181B (en) 1984-12-28
DK281782A (da) 1982-12-25
FI822235A0 (fi) 1982-06-22
PT75108A (de) 1982-07-01
AU8512682A (en) 1983-01-06
EP0069254A1 (de) 1983-01-12
NO822075L (no) 1982-12-27
PT75108B (de) 1985-05-31
DE3124701A1 (de) 1983-01-13
GR76834B (ko) 1984-09-04
ES513376A0 (es) 1983-07-01
FI822235L (fi) 1982-12-25
PL237053A1 (en) 1983-01-17

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