KR20240097876A - 신규한 올리고당, 그 올리고당의 제조 중간체, 및 그들의 제조 방법 - Google Patents

신규한 올리고당, 그 올리고당의 제조 중간체, 및 그들의 제조 방법 Download PDF

Info

Publication number
KR20240097876A
KR20240097876A KR1020247017489A KR20247017489A KR20240097876A KR 20240097876 A KR20240097876 A KR 20240097876A KR 1020247017489 A KR1020247017489 A KR 1020247017489A KR 20247017489 A KR20247017489 A KR 20247017489A KR 20240097876 A KR20240097876 A KR 20240097876A
Authority
KR
South Korea
Prior art keywords
compound represented
formula
group
water
hydrophobic carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247017489A
Other languages
English (en)
Korean (ko)
Inventor
츠요시 우에다
류세이 이토
다츠야 나카무라
게이스케 스즈키
사토시 나카네
저쿤 양
Original Assignee
다이이찌 산쿄 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 다이이찌 산쿄 가부시키가이샤 filed Critical 다이이찌 산쿄 가부시키가이샤
Publication of KR20240097876A publication Critical patent/KR20240097876A/ko
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Sustainable Development (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
KR1020247017489A 2021-10-29 2022-10-28 신규한 올리고당, 그 올리고당의 제조 중간체, 및 그들의 제조 방법 Pending KR20240097876A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2021178383 2021-10-29
JPJP-P-2021-178383 2021-10-29
JP2022005353 2022-01-17
JPJP-P-2022-005353 2022-01-17
PCT/JP2022/040346 WO2023074843A1 (ja) 2021-10-29 2022-10-28 新規なオリゴ糖、該オリゴ糖の製造中間体、及びそれらの製造方法

Publications (1)

Publication Number Publication Date
KR20240097876A true KR20240097876A (ko) 2024-06-27

Family

ID=86160002

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247017489A Pending KR20240097876A (ko) 2021-10-29 2022-10-28 신규한 올리고당, 그 올리고당의 제조 중간체, 및 그들의 제조 방법

Country Status (8)

Country Link
US (1) US20250346622A1 (https=)
EP (1) EP4424717A4 (https=)
JP (1) JPWO2023074843A1 (https=)
KR (1) KR20240097876A (https=)
CA (1) CA3236388A1 (https=)
IL (1) IL312410A (https=)
TW (1) TW202334175A (https=)
WO (1) WO2023074843A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250064682A (ko) * 2022-09-09 2025-05-09 다이이찌 산쿄 가부시키가이샤 신규 올리고당, 그 올리고당의 제조 중간체, 및 그것들의 제조 방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS601267U (ja) 1983-06-20 1985-01-08 凸版印刷株式会社 実験用小動物飼育箱のフタ
WO1996002255A1 (en) 1994-07-15 1996-02-01 Taiyo Kagaku Co., Ltd. Medicinal composition containing sialic acid derivative
WO2002016384A2 (en) 2000-08-18 2002-02-28 Massachusetts Institute Of Technology Apparatus and methods for the automated synthesis of oligosaccharides
WO2011027868A1 (ja) 2009-09-03 2011-03-10 公益財団法人野口研究所 11糖シアリルオリゴ糖ペプチドの製造方法
WO2014208742A1 (ja) 2013-06-28 2014-12-31 第一三共株式会社 オリゴ糖ペプチドの精製方法
WO2017110984A1 (ja) 2015-12-25 2017-06-29 第一三共株式会社 限外ろ過膜を用いたオリゴ糖ペプチドの精製法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2451971C (en) * 2001-06-19 2010-09-07 Otsuka Chemical Co., Ltd. Process for producing sugar chain asparagine derivative
JP6001267B2 (ja) 2011-12-31 2016-10-05 公益財団法人野口研究所 炭素−炭素結合型ヘビーフルオラスタグ
US11559581B2 (en) 2015-01-09 2023-01-24 Oxford University Innovation Limited Antibody conjugates and methods of making the antibody conjugates
EP3426693A4 (en) * 2016-03-08 2019-11-13 Academia Sinica PROCESS FOR MODULAR SYNTHESIS OF N-GLYCANES AND ARRANGEMENTS THEREOF
NZ762505A (en) 2017-09-29 2026-03-27 Daiichi Sankyo Co Ltd Antibody-pyrrolobenzodiazepine derivative conjugate
EP3492482A1 (en) * 2017-11-30 2019-06-05 Vaxxilon AG Vaccine against klebsiella pneumoniae
EP3848054B1 (en) 2018-09-06 2025-01-29 Daiichi Sankyo Company, Limited Antibody-drug conjugates of cyclic dinucleotide derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS601267U (ja) 1983-06-20 1985-01-08 凸版印刷株式会社 実験用小動物飼育箱のフタ
WO1996002255A1 (en) 1994-07-15 1996-02-01 Taiyo Kagaku Co., Ltd. Medicinal composition containing sialic acid derivative
WO2002016384A2 (en) 2000-08-18 2002-02-28 Massachusetts Institute Of Technology Apparatus and methods for the automated synthesis of oligosaccharides
WO2011027868A1 (ja) 2009-09-03 2011-03-10 公益財団法人野口研究所 11糖シアリルオリゴ糖ペプチドの製造方法
WO2014208742A1 (ja) 2013-06-28 2014-12-31 第一三共株式会社 オリゴ糖ペプチドの精製方法
WO2017110984A1 (ja) 2015-12-25 2017-06-29 第一三共株式会社 限外ろ過膜を用いたオリゴ糖ペプチドの精製法

Non-Patent Citations (15)

* Cited by examiner, † Cited by third party
Title
Angew. Chem. Int. Ed. 2021, 60, 19287-19296
Angew. Chem. Int. Ed. 2021, 60, 24686-24693
BeilsteinJ. Org. Chem. 2018, 14, 416-429
J. AM. CHEM. SOC. 2005, 127, 7296-7297
J. Am. Chem. Soc. 2009, 131, 16669-16671
J. Am. Chem. Soc. 2018, 140, 4632-4638
J. Am. Chem. Soc. 2019, 141, 6484-6488
J. Org. Chem. 2016, 81, 10600-10616
J. Org. Chem., 2017, 82, 3926-3934
Org. Biomol. Chem. 2018, 16, 4720-4727
Org. Lett. 2002, 4, 4551-4554
Org. Process. Res. Dev. 2021, 25, 10, 2270-2276
Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 10611-10616
TetrahedronLett. 1986, 27, 5739-5742
유기 합성 협회지, 2002년 60권 5호 p.494-495

Also Published As

Publication number Publication date
WO2023074843A1 (ja) 2023-05-04
TW202334175A (zh) 2023-09-01
JPWO2023074843A1 (https=) 2023-05-04
IL312410A (en) 2024-06-01
EP4424717A4 (en) 2025-11-05
EP4424717A1 (en) 2024-09-04
US20250346622A1 (en) 2025-11-13
CA3236388A1 (en) 2023-05-04

Similar Documents

Publication Publication Date Title
US20110245488A1 (en) Process for the synthesis of l-fucosyl di- or oligo-saccharides and novel 2,3,4 tribenzyl-fucosyl derivatives intermediates thereof
EP4585601A1 (en) Novel oligosaccharide, production intermediate for novel oligosaccharide, production method for novel oligosaccharide, and production method for production intermediate for novel oligosaccharide
CN103703012A (zh) 乳糖-n-四糖的制造
JPH0899989A (ja) 新規糖脂質誘導体およびその製造用中間体
CA3131096A1 (en) Sialidase-resistant saccharide and method of making and using the same
KR20240097876A (ko) 신규한 올리고당, 그 올리고당의 제조 중간체, 및 그들의 제조 방법
JP2025160360A (ja) 糖鎖及び糖鎖を含む医薬品の製造方法
Sato et al. Selective cross-metathesis of cellobiose derivatives with amido-functionalized olefinic structures: A model study for synthesis of cellulosic diblock copolymers
CN118302451A (zh) 新型寡糖、该寡糖的制造中间体、以及它们的制造方法
Amin et al. Synthesis of asparagine-linked bacillosamine
HK40109704A (en) Novel oligosaccharide, manufacturing intermediate for novel oligosaccharide, and method for manufacturing these
Nishiyama et al. Synthesis of fluorescence-labeled Galβ1-3Fuc and Galβ1-4Fuc as probes for the endogenous glyco-epitope recognized by galectins in Caenorhabditis elegans
EP0403366B1 (fr) Dérivés de cyclomalto-oligosaccharides et leurs procédés de préparation
JP6198207B2 (ja) 新規糖供与体及びそれを用いた糖鎖の合成方法
HK40106086A (en) Glycan, and method for producing medicine containing glycan
US10640526B2 (en) Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose
JP5015505B2 (ja) コア4型構造を有するo−結合型糖タンパク質糖鎖関連化合物およびその製造方法
KR100966986B1 (ko) 1,2―트랜스글리코시드 화합물의 제조방법
van Hengst et al. Influence of N-protecting groups on the reactivity of glycosyl acceptors
JP4813838B2 (ja) コア6型構造を有するo−結合型糖アミノ酸誘導体およびその製造方法
EP3421480A1 (en) Method for separating chromatographically indistinguishable azidonitrates
WO2022191312A1 (ja) 新規な脱アルコキシフェニル化反応
JP2004099575A (ja) 新規d−ガラクトサミン誘導体,およびそれを用いるムチンコア2クラスの合成法

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13 Application amended

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000