KR20230156817A - 키메라 단백질 - Google Patents

키메라 단백질 Download PDF

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Publication number
KR20230156817A
KR20230156817A KR1020237038544A KR20237038544A KR20230156817A KR 20230156817 A KR20230156817 A KR 20230156817A KR 1020237038544 A KR1020237038544 A KR 1020237038544A KR 20237038544 A KR20237038544 A KR 20237038544A KR 20230156817 A KR20230156817 A KR 20230156817A
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cells
gly
leu
ser
glu
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Korean (ko)
Inventor
마틴 풀레
라이언 트로브리지
에드워드 호지킨
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오토러스 리미티드
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C12N2510/00—Genetically modified cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020237038544A 2015-02-24 2016-02-23 키메라 단백질 Pending KR20230156817A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB201503133A GB201503133D0 (en) 2015-02-24 2015-02-24 Chimeric protein
GB1503133.9 2015-02-24
KR1020177025985A KR102601849B1 (ko) 2015-02-24 2016-02-23 키메라 단백질
PCT/GB2016/050451 WO2016135470A1 (en) 2015-02-24 2016-02-23 Chimeric protein

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020177025985A Division KR102601849B1 (ko) 2015-02-24 2016-02-23 키메라 단백질

Publications (1)

Publication Number Publication Date
KR20230156817A true KR20230156817A (ko) 2023-11-14

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ID=52822149

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020237038544A Pending KR20230156817A (ko) 2015-02-24 2016-02-23 키메라 단백질
KR1020177025985A Active KR102601849B1 (ko) 2015-02-24 2016-02-23 키메라 단백질

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020177025985A Active KR102601849B1 (ko) 2015-02-24 2016-02-23 키메라 단백질

Country Status (20)

Country Link
US (3) US10098911B2 (https=)
EP (2) EP4147696A1 (https=)
JP (4) JP6836508B2 (https=)
KR (2) KR20230156817A (https=)
CN (2) CN107207621B (https=)
AU (1) AU2016225190B2 (https=)
CA (1) CA2973107C (https=)
CL (1) CL2017002134A1 (https=)
DK (1) DK3197453T3 (https=)
ES (1) ES2930623T3 (https=)
GB (1) GB201503133D0 (https=)
HU (1) HUE060267T2 (https=)
IL (1) IL252840B (https=)
MX (1) MX392658B (https=)
PL (1) PL3197453T3 (https=)
PT (1) PT3197453T (https=)
RU (1) RU2746755C2 (https=)
SG (1) SG11201705300VA (https=)
WO (1) WO2016135470A1 (https=)
ZA (1) ZA201704231B (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201503133D0 (en) * 2015-02-24 2015-04-08 Ucl Business Plc And Syncona Partners Llp Chimeric protein
US20170166877A1 (en) * 2015-12-14 2017-06-15 Bellicum Pharmaceuticals, Inc. Dual controls for therapeutic cell activation or elimination
ES3051391T3 (en) 2016-10-06 2025-12-29 Poseida Therapeutics Inc Inducible caspases and methods for use
CN110191955B (zh) * 2016-12-13 2024-05-31 西雅图儿童医院（Dba西雅图儿童研究所） 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法
JP2020503390A (ja) 2017-01-09 2020-01-30 オイシン バイオテクノロジーズ， インコーポレイテッド 治療用タンパク質の標的細胞特異的な産生のため、および標的細胞に関連する疾患、状態、または障害の治療のための、膜融合性脂質ナノ粒子、ならびにその作製および使用のための方法
GB201709203D0 (en) 2017-06-09 2017-07-26 Autolus Ltd Antigen-binding domain
US20210130775A1 (en) * 2017-08-02 2021-05-06 Autolus Limited Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed
CN109593721B (zh) * 2017-09-30 2022-11-01 亘喜生物科技（上海）有限公司 具有自杀基因开关的靶向人间皮素的工程化免疫细胞
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