KR20230066453A - 비바이러스성 dna 벡터 및 fviii 치료제 발현을 위한 이의 용도 - Google Patents
비바이러스성 dna 벡터 및 fviii 치료제 발현을 위한 이의 용도 Download PDFInfo
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| US63/079,349 | 2020-09-16 | ||
| US202063132838P | 2020-12-31 | 2020-12-31 | |
| US63/132,838 | 2020-12-31 | ||
| PCT/US2021/050715 WO2022061014A1 (en) | 2020-09-16 | 2021-09-16 | Non-viral dna vectors and uses thereof for expressing fviii therapeutics |
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| CA2656558A1 (en) * | 2006-06-30 | 2008-01-10 | The Regents Of The University Of Michigan | Method of producing factor viii proteins by recombinant methods |
| GB0911870D0 (en) * | 2009-07-08 | 2009-08-19 | Ucl Business Plc | Optimised coding sequence and promoter |
| AU2013336601B2 (en) * | 2012-10-26 | 2018-01-25 | Vrije Universiteit Brussel | Vector for liver-directed gene therapy of hemophilia and methods and use thereof |
| GB2526339A (en) * | 2014-05-21 | 2015-11-25 | Imp Innovations Ltd | Lentiviral vectors |
| PL231230B1 (pl) * | 2015-03-11 | 2019-02-28 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Czynnik zwiększający efektywność szczepionki DNA skierowanej przeciw wirusowi, preparat plazmidowy DNA, szczepionka DNA, sposób otrzymywania zmodyfikowanego wektora ekspresyjnego oraz zastosowanie sekwencji nukleotydowej rozpoznawanej przez czynnik NF kappa B |
| MX2018010633A (es) * | 2016-03-03 | 2019-06-13 | Univ Massachusetts | Acido desoxirribonucleico (adn) lineal duplex de extremos cerrados para transferencia genica no viral. |
| NZ762100A (en) * | 2017-08-09 | 2025-12-19 | Bioverativ Therapeutics Inc | Nucleic acid molecules and uses thereof |
| CA3075168A1 (en) * | 2017-09-08 | 2019-03-14 | Generation Bio Co. | Modified closed-ended dna (cedna) |
| CA3084185A1 (en) * | 2017-12-06 | 2019-06-13 | Generation Bio Co. | Gene editing using a modified closed-ended dna (cedna) |
| MA52116A (fr) * | 2018-03-02 | 2021-01-06 | Generation Bio Co | Vecteurs d'adn à extrémité fermée (cedna) pour l'insertion de transgènes au niveau de havres génomiques sécuritaires (gsh) dans des génomes humains et murins |
| SG11202108357PA (en) * | 2019-02-15 | 2021-08-30 | Crispr Therapeutics Ag | Gene editing for hemophilia a with improved factor viii expression |
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| US20230383311A1 (en) | 2023-11-30 |
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| EP4214315A1 (en) | 2023-07-26 |
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