KR20230057350A - 스테이플화된 펩티드 및 이의 방법 - Google Patents

스테이플화된 펩티드 및 이의 방법 Download PDF

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Publication number
KR20230057350A
KR20230057350A KR1020237005577A KR20237005577A KR20230057350A KR 20230057350 A KR20230057350 A KR 20230057350A KR 1020237005577 A KR1020237005577 A KR 1020237005577A KR 20237005577 A KR20237005577 A KR 20237005577A KR 20230057350 A KR20230057350 A KR 20230057350A
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KR
South Korea
Prior art keywords
independently
agent
optionally substituted
group
amino acid
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Pending
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KR1020237005577A
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English (en)
Korean (ko)
Inventor
브라이언 핼버트 화이트
야광 시
마틴 로버트 트렘블레이
데보라 게일 콘레디
웨-메이 장
이반 터커 주잇
로렌소 호수에 알파로-로페스
사라 이사벨 카푸치
지 리
존 헤니 맥기
Original Assignee
포그 파마슈티컬스 인코포레이티드
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Publication of KR20230057350A publication Critical patent/KR20230057350A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020237005577A 2020-07-22 2021-07-22 스테이플화된 펩티드 및 이의 방법 Pending KR20230057350A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063055308P 2020-07-22 2020-07-22
US63/055,308 2020-07-22
US202163208494P 2021-06-08 2021-06-08
US63/208,494 2021-06-08
PCT/US2021/042856 WO2022020652A2 (en) 2020-07-22 2021-07-22 Stapled peptides and methods thereof

Publications (1)

Publication Number Publication Date
KR20230057350A true KR20230057350A (ko) 2023-04-28

Family

ID=79728982

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237005577A Pending KR20230057350A (ko) 2020-07-22 2021-07-22 스테이플화된 펩티드 및 이의 방법

Country Status (10)

Country Link
US (1) US20240116985A1 (https=)
EP (1) EP4185599A4 (https=)
JP (1) JP2023535026A (https=)
KR (1) KR20230057350A (https=)
CN (1) CN116323638A (https=)
AU (1) AU2021314310A1 (https=)
CA (1) CA3186681A1 (https=)
IL (1) IL299907A (https=)
MX (1) MX2023000947A (https=)
WO (1) WO2022020652A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018329956A1 (en) 2017-09-07 2020-08-20 Fog Pharmaceuticals, Inc. Agents modulating beta-catenin functions and methods thereof
MX2021001943A (es) 2018-08-20 2021-07-15 Fog Pharmaceuticals Inc Colecciones de péptidos, agentes peptídicos y métodos de uso de los mismos.
KR20240031957A (ko) * 2021-06-08 2024-03-08 포그 파마슈티컬스 인코포레이티드 스테이플화된 펩티드 및 이의 방법
CN115260060A (zh) * 2022-09-07 2022-11-01 康化（上海）新药研发有限公司 (2s)-2-n-芴甲氧羰基氨基-5,5-二甲基正亮氨酸的合成方法
WO2024054892A1 (en) * 2022-09-09 2024-03-14 Shape Therapeutics Inc. Therapeutic peptides
WO2024130217A1 (en) * 2022-12-15 2024-06-20 Fog Pharmaceuticals, Inc. Stapled peptides and methods thereof
CN120529912A (zh) * 2022-12-15 2025-08-22 帕拉比利斯药物公司 订书钉化肽及其方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5671196A (en) * 1996-03-28 1997-10-17 Immulogic Pharmaceutical Corporation Myelin oligodendrocyte glycoprotein peptides and uses thereof
US20040181830A1 (en) * 2001-05-07 2004-09-16 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
EP2254592B1 (en) * 2008-02-28 2019-06-05 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease
WO2010009987A2 (en) * 2008-07-21 2010-01-28 Probiodrug Ag Diagnostic antibody assay
EP2337795A2 (en) * 2008-10-01 2011-06-29 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring
WO2012040459A2 (en) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
WO2014026033A1 (en) * 2012-08-08 2014-02-13 University Of Florida Research Foundation, Inc. Cross-reactive t cell epitopes of hiv, siv, and fiv for vaccines in humans and cats
GB2563875B (en) * 2017-06-28 2020-08-19 Sutura Therapeutics Ltd Improvements in drug delivery
AU2018329956A1 (en) * 2017-09-07 2020-08-20 Fog Pharmaceuticals, Inc. Agents modulating beta-catenin functions and methods thereof
WO2019178313A1 (en) * 2018-03-14 2019-09-19 Dana-Farber Cancer Institute, Inc. Stabilized peptides for biomarker detection

Also Published As

Publication number Publication date
JP2023535026A (ja) 2023-08-15
MX2023000947A (es) 2023-02-22
WO2022020652A3 (en) 2022-03-03
AU2021314310A1 (en) 2023-03-16
CN116323638A (zh) 2023-06-23
EP4185599A4 (en) 2024-08-28
CA3186681A1 (en) 2022-01-27
US20240116985A1 (en) 2024-04-11
IL299907A (en) 2023-03-01
EP4185599A2 (en) 2023-05-31
WO2022020652A2 (en) 2022-01-27

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