CA3186681A1 - Stapled peptides and methods thereof - Google Patents

Stapled peptides and methods thereof

Info

Publication number
CA3186681A1
CA3186681A1 CA3186681A CA3186681A CA3186681A1 CA 3186681 A1 CA3186681 A1 CA 3186681A1 CA 3186681 A CA3186681 A CA 3186681A CA 3186681 A CA3186681 A CA 3186681A CA 3186681 A1 CA3186681 A1 CA 3186681A1
Authority
CA
Canada
Prior art keywords
agent
independently
optionally substituted
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3186681A
Other languages
English (en)
French (fr)
Inventor
Brian Halbert WHITE
Yaguang Si
Martin Robert TREMBLAY
Deborah Gail Conrady
Yue-Mei Zhang
Ivan Tucker JEWETT
Lorenzo Josue Alfaro-Lopez
Sarah Isabelle CAPPUCCI
Zhi Li
John Hanney Mcgee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fog Pharmaceuticals Inc
Original Assignee
Fog Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fog Pharmaceuticals Inc filed Critical Fog Pharmaceuticals Inc
Publication of CA3186681A1 publication Critical patent/CA3186681A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3186681A 2020-07-22 2021-07-22 Stapled peptides and methods thereof Pending CA3186681A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063055308P 2020-07-22 2020-07-22
US63/055,308 2020-07-22
US202163208494P 2021-06-08 2021-06-08
US63/208,494 2021-06-08
PCT/US2021/042856 WO2022020652A2 (en) 2020-07-22 2021-07-22 Stapled peptides and methods thereof

Publications (1)

Publication Number Publication Date
CA3186681A1 true CA3186681A1 (en) 2022-01-27

Family

ID=79728982

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3186681A Pending CA3186681A1 (en) 2020-07-22 2021-07-22 Stapled peptides and methods thereof

Country Status (10)

Country Link
US (1) US20240116985A1 (https=)
EP (1) EP4185599A4 (https=)
JP (1) JP2023535026A (https=)
KR (1) KR20230057350A (https=)
CN (1) CN116323638A (https=)
AU (1) AU2021314310A1 (https=)
CA (1) CA3186681A1 (https=)
IL (1) IL299907A (https=)
MX (1) MX2023000947A (https=)
WO (1) WO2022020652A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018329956A1 (en) 2017-09-07 2020-08-20 Fog Pharmaceuticals, Inc. Agents modulating beta-catenin functions and methods thereof
MX2021001943A (es) 2018-08-20 2021-07-15 Fog Pharmaceuticals Inc Colecciones de péptidos, agentes peptídicos y métodos de uso de los mismos.
KR20240031957A (ko) * 2021-06-08 2024-03-08 포그 파마슈티컬스 인코포레이티드 스테이플화된 펩티드 및 이의 방법
CN115260060A (zh) * 2022-09-07 2022-11-01 康化（上海）新药研发有限公司 (2s)-2-n-芴甲氧羰基氨基-5,5-二甲基正亮氨酸的合成方法
WO2024054892A1 (en) * 2022-09-09 2024-03-14 Shape Therapeutics Inc. Therapeutic peptides
WO2024130217A1 (en) * 2022-12-15 2024-06-20 Fog Pharmaceuticals, Inc. Stapled peptides and methods thereof
CN120529912A (zh) * 2022-12-15 2025-08-22 帕拉比利斯药物公司 订书钉化肽及其方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5671196A (en) * 1996-03-28 1997-10-17 Immulogic Pharmaceutical Corporation Myelin oligodendrocyte glycoprotein peptides and uses thereof
US20040181830A1 (en) * 2001-05-07 2004-09-16 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
EP2254592B1 (en) * 2008-02-28 2019-06-05 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease
WO2010009987A2 (en) * 2008-07-21 2010-01-28 Probiodrug Ag Diagnostic antibody assay
EP2337795A2 (en) * 2008-10-01 2011-06-29 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring
WO2012040459A2 (en) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
WO2014026033A1 (en) * 2012-08-08 2014-02-13 University Of Florida Research Foundation, Inc. Cross-reactive t cell epitopes of hiv, siv, and fiv for vaccines in humans and cats
GB2563875B (en) * 2017-06-28 2020-08-19 Sutura Therapeutics Ltd Improvements in drug delivery
AU2018329956A1 (en) * 2017-09-07 2020-08-20 Fog Pharmaceuticals, Inc. Agents modulating beta-catenin functions and methods thereof
WO2019178313A1 (en) * 2018-03-14 2019-09-19 Dana-Farber Cancer Institute, Inc. Stabilized peptides for biomarker detection

Also Published As

Publication number Publication date
JP2023535026A (ja) 2023-08-15
MX2023000947A (es) 2023-02-22
WO2022020652A3 (en) 2022-03-03
AU2021314310A1 (en) 2023-03-16
CN116323638A (zh) 2023-06-23
KR20230057350A (ko) 2023-04-28
EP4185599A4 (en) 2024-08-28
US20240116985A1 (en) 2024-04-11
IL299907A (en) 2023-03-01
EP4185599A2 (en) 2023-05-31
WO2022020652A2 (en) 2022-01-27

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