JP2023535026A - ステープルペプチドおよびその方法 - Google Patents

ステープルペプチドおよびその方法 Download PDF

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Publication number
JP2023535026A
JP2023535026A JP2023504288A JP2023504288A JP2023535026A JP 2023535026 A JP2023535026 A JP 2023535026A JP 2023504288 A JP2023504288 A JP 2023504288A JP 2023504288 A JP2023504288 A JP 2023504288A JP 2023535026 A JP2023535026 A JP 2023535026A
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Japan
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independently
group
agent
optionally substituted
amino acid
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JP2023504288A
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Japanese (ja)
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JP2023535026A5 (https=
Inventor
ブライアン ハルバート ホワイト，
ヤグアン シー，
マーティン ロバート トレンブレイ，
デボラ ゲイル コンラディ，
ユエ－メイ ジャン，
イヴァン タッカー ジュウェット，
ロレンツォ ジョズエ アルファロ－ロペス，
サラ イザベル カプッチ，
ジー リー，
ジョン ハニー マギー，
Original Assignee
フォグ ファーマシューティカルズ， インコーポレイテッド
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Publication of JP2023535026A publication Critical patent/JP2023535026A/ja
Publication of JP2023535026A5 publication Critical patent/JP2023535026A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2023504288A 2020-07-22 2021-07-22 ステープルペプチドおよびその方法 Pending JP2023535026A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063055308P 2020-07-22 2020-07-22
US63/055,308 2020-07-22
US202163208494P 2021-06-08 2021-06-08
US63/208,494 2021-06-08
PCT/US2021/042856 WO2022020652A2 (en) 2020-07-22 2021-07-22 Stapled peptides and methods thereof

Publications (2)

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JP2023535026A true JP2023535026A (ja) 2023-08-15
JP2023535026A5 JP2023535026A5 (https=) 2024-08-08

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ID=79728982

Family Applications (1)

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JP2023504288A Pending JP2023535026A (ja) 2020-07-22 2021-07-22 ステープルペプチドおよびその方法

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US (1) US20240116985A1 (https=)
EP (1) EP4185599A4 (https=)
JP (1) JP2023535026A (https=)
KR (1) KR20230057350A (https=)
CN (1) CN116323638A (https=)
AU (1) AU2021314310A1 (https=)
CA (1) CA3186681A1 (https=)
IL (1) IL299907A (https=)
MX (1) MX2023000947A (https=)
WO (1) WO2022020652A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018329956A1 (en) 2017-09-07 2020-08-20 Fog Pharmaceuticals, Inc. Agents modulating beta-catenin functions and methods thereof
MX2021001943A (es) 2018-08-20 2021-07-15 Fog Pharmaceuticals Inc Colecciones de péptidos, agentes peptídicos y métodos de uso de los mismos.
KR20240031957A (ko) * 2021-06-08 2024-03-08 포그 파마슈티컬스 인코포레이티드 스테이플화된 펩티드 및 이의 방법
CN115260060A (zh) * 2022-09-07 2022-11-01 康化（上海）新药研发有限公司 (2s)-2-n-芴甲氧羰基氨基-5,5-二甲基正亮氨酸的合成方法
WO2024054892A1 (en) * 2022-09-09 2024-03-14 Shape Therapeutics Inc. Therapeutic peptides
WO2024130217A1 (en) * 2022-12-15 2024-06-20 Fog Pharmaceuticals, Inc. Stapled peptides and methods thereof
CN120529912A (zh) * 2022-12-15 2025-08-22 帕拉比利斯药物公司 订书钉化肽及其方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012040459A2 (en) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
WO2019051327A2 (en) * 2017-09-07 2019-03-14 Fog Pharmaceuticals, Inc. BETA CATENIN FUNCTIONALIZATION AGENTS AND ASSOCIATED METHODS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5671196A (en) * 1996-03-28 1997-10-17 Immulogic Pharmaceutical Corporation Myelin oligodendrocyte glycoprotein peptides and uses thereof
US20040181830A1 (en) * 2001-05-07 2004-09-16 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
EP2254592B1 (en) * 2008-02-28 2019-06-05 Dako Denmark A/S Mhc multimers in borrelia diagnostics and disease
WO2010009987A2 (en) * 2008-07-21 2010-01-28 Probiodrug Ag Diagnostic antibody assay
EP2337795A2 (en) * 2008-10-01 2011-06-29 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring
WO2014026033A1 (en) * 2012-08-08 2014-02-13 University Of Florida Research Foundation, Inc. Cross-reactive t cell epitopes of hiv, siv, and fiv for vaccines in humans and cats
GB2563875B (en) * 2017-06-28 2020-08-19 Sutura Therapeutics Ltd Improvements in drug delivery
WO2019178313A1 (en) * 2018-03-14 2019-09-19 Dana-Farber Cancer Institute, Inc. Stabilized peptides for biomarker detection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012040459A2 (en) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
WO2019051327A2 (en) * 2017-09-07 2019-03-14 Fog Pharmaceuticals, Inc. BETA CATENIN FUNCTIONALIZATION AGENTS AND ASSOCIATED METHODS

Also Published As

Publication number Publication date
MX2023000947A (es) 2023-02-22
WO2022020652A3 (en) 2022-03-03
AU2021314310A1 (en) 2023-03-16
CN116323638A (zh) 2023-06-23
KR20230057350A (ko) 2023-04-28
EP4185599A4 (en) 2024-08-28
CA3186681A1 (en) 2022-01-27
US20240116985A1 (en) 2024-04-11
IL299907A (en) 2023-03-01
EP4185599A2 (en) 2023-05-31
WO2022020652A2 (en) 2022-01-27

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