KR20230057350A - 스테이플화된 펩티드 및 이의 방법 - Google Patents

스테이플화된 펩티드 및 이의 방법 Download PDF

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Publication number
KR20230057350A
KR20230057350A KR1020237005577A KR20237005577A KR20230057350A KR 20230057350 A KR20230057350 A KR 20230057350A KR 1020237005577 A KR1020237005577 A KR 1020237005577A KR 20237005577 A KR20237005577 A KR 20237005577A KR 20230057350 A KR20230057350 A KR 20230057350A
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KR
South Korea
Prior art keywords
independently
agent
optionally substituted
group
amino acid
Prior art date
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KR1020237005577A
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English (en)
Korean (ko)
Inventor
브라이언 핼버트 화이트
야광 시
마틴 로버트 트렘블레이
데보라 게일 콘레디
웨-메이 장
이반 터커 주잇
로렌소 호수에 알파로-로페스
사라 이사벨 카푸치
지 리
존 헤니 맥기
Original Assignee
포그 파마슈티컬스 인코포레이티드
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Publication of KR20230057350A publication Critical patent/KR20230057350A/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020237005577A 2020-07-22 2021-07-22 스테이플화된 펩티드 및 이의 방법 KR20230057350A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063055308P 2020-07-22 2020-07-22
US63/055,308 2020-07-22
US202163208494P 2021-06-08 2021-06-08
US63/208,494 2021-06-08
PCT/US2021/042856 WO2022020652A2 (fr) 2020-07-22 2021-07-22 Peptides agrafés et utilisations associées

Publications (1)

Publication Number Publication Date
KR20230057350A true KR20230057350A (ko) 2023-04-28

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ID=79728982

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237005577A KR20230057350A (ko) 2020-07-22 2021-07-22 스테이플화된 펩티드 및 이의 방법

Country Status (10)

Country Link
US (1) US20240116985A1 (fr)
EP (1) EP4185599A4 (fr)
JP (1) JP2023535026A (fr)
KR (1) KR20230057350A (fr)
CN (1) CN116323638A (fr)
AU (1) AU2021314310A1 (fr)
CA (1) CA3186681A1 (fr)
IL (1) IL299907A (fr)
MX (1) MX2023000947A (fr)
WO (1) WO2022020652A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200064075A (ko) 2017-09-07 2020-06-05 포그 파마슈티컬스 인코포레이티드 베타-카테닌 기능을 조절하는 제제 및 이의 방법
CN115260060A (zh) * 2022-09-07 2022-11-01 康化(上海)新药研发有限公司 (2s)-2-n-芴甲氧羰基氨基-5,5-二甲基正亮氨酸的合成方法
WO2024054892A1 (fr) * 2022-09-09 2024-03-14 Shape Therapeutics Inc. Peptides thérapeutiques
WO2024130217A1 (fr) * 2022-12-15 2024-06-20 Fog Pharmaceuticals, Inc. Peptides agrafés et procédés associés
WO2024130218A1 (fr) * 2022-12-15 2024-06-20 Fog Pharmaceuticals, Inc. Peptides agrafés et procédés associés

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5671196A (en) * 1996-03-28 1997-10-17 Immulogic Pharmaceutical Corporation Myelin oligodendrocyte glycoprotein peptides and uses thereof
US20040181830A1 (en) * 2001-05-07 2004-09-16 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
EP2254592B1 (fr) * 2008-02-28 2019-06-05 Dako Denmark A/S Multimères de mhc dans le diagnostic et le traitement de la borréliose
EA028427B1 (ru) * 2008-07-21 2017-11-30 Пробиодруг Аг АНТИТЕЛО, СВЯЗЫВАЮЩЕЕСЯ С Aβ-ПЕПТИДАМИ ИЛИ ИХ ВАРИАНТАМИ, КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ЭТО АНТИТЕЛО, И ЕГО ПРИМЕНЕНИЕ
EP2337795A2 (fr) * 2008-10-01 2011-06-29 Dako Denmark A/S Multimères de mhc dans des vaccins et la surveillance immunitaire contre le cancer
WO2012040459A2 (fr) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Peptides de ciblage de la béta-caténine et leurs utilisations
WO2014026033A1 (fr) * 2012-08-08 2014-02-13 University Of Florida Research Foundation, Inc. Epitopes de lymphocytes t à réactivité croisée du vih, du vis et du vif pour des vaccins destinés à des humains et à des chats
GB2563875B (en) * 2017-06-28 2020-08-19 Sutura Therapeutics Ltd Improvements in drug delivery
KR20200064075A (ko) * 2017-09-07 2020-06-05 포그 파마슈티컬스 인코포레이티드 베타-카테닌 기능을 조절하는 제제 및 이의 방법
WO2019178313A1 (fr) * 2018-03-14 2019-09-19 Dana-Farber Cancer Institute, Inc. Peptides stabilisés de détection de biomarqueurs

Also Published As

Publication number Publication date
WO2022020652A2 (fr) 2022-01-27
EP4185599A4 (fr) 2024-08-28
JP2023535026A (ja) 2023-08-15
EP4185599A2 (fr) 2023-05-31
IL299907A (en) 2023-03-01
CN116323638A (zh) 2023-06-23
CA3186681A1 (fr) 2022-01-27
WO2022020652A3 (fr) 2022-03-03
US20240116985A1 (en) 2024-04-11
AU2021314310A1 (en) 2023-03-16
MX2023000947A (es) 2023-02-22

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