KR20230005984A - 유전자 발현을 활성화 및 침묵시키기 위해 효과기 도메인을 제조, 동정 및 특성규명하기 위한 조성물, 시스템 및 방법 - Google Patents

유전자 발현을 활성화 및 침묵시키기 위해 효과기 도메인을 제조, 동정 및 특성규명하기 위한 조성물, 시스템 및 방법 Download PDF

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KR20230005984A
KR20230005984A KR1020227042321A KR20227042321A KR20230005984A KR 20230005984 A KR20230005984 A KR 20230005984A KR 1020227042321 A KR1020227042321 A KR 1020227042321A KR 20227042321 A KR20227042321 A KR 20227042321A KR 20230005984 A KR20230005984 A KR 20230005984A
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마이클 씨. 바씩
조쉬 틱코
갤런 티. 헤스
라크라미오아라 빈투
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더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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KR1020227042321A 2020-05-04 2021-05-04 유전자 발현을 활성화 및 침묵시키기 위해 효과기 도메인을 제조, 동정 및 특성규명하기 위한 조성물, 시스템 및 방법 Pending KR20230005984A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063019706P 2020-05-04 2020-05-04
US63/019,706 2020-05-04
US202063074793P 2020-09-04 2020-09-04
US63/074,793 2020-09-04
PCT/US2021/030643 WO2021226077A2 (en) 2020-05-04 2021-05-04 Compositions, systems, and methods for the generation, identification, and characterization of effector domains for activating and silencing gene expression

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KR20230005984A true KR20230005984A (ko) 2023-01-10

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KR1020227042321A Pending KR20230005984A (ko) 2020-05-04 2021-05-04 유전자 발현을 활성화 및 침묵시키기 위해 효과기 도메인을 제조, 동정 및 특성규명하기 위한 조성물, 시스템 및 방법

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US (1) US20240401032A1 (https=)
EP (2) EP4644573A3 (https=)
JP (1) JP2023524733A (https=)
KR (1) KR20230005984A (https=)
CN (1) CN116234902A (https=)
AU (1) AU2021268634A1 (https=)
CA (1) CA3176046A1 (https=)
ES (1) ES3036984T3 (https=)
WO (1) WO2021226077A2 (https=)

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JP2023524733A (ja) 2023-06-13
EP4644573A2 (en) 2025-11-05
EP4146801A4 (en) 2024-06-26
WO2021226077A2 (en) 2021-11-11
AU2021268634A1 (en) 2022-11-24
US20240401032A1 (en) 2024-12-05
ES3036984T3 (en) 2025-09-26
EP4146801A2 (en) 2023-03-15
CA3176046A1 (en) 2021-11-11
EP4146801B1 (en) 2025-07-02
WO2021226077A3 (en) 2022-02-03
EP4644573A3 (en) 2026-01-14
CN116234902A (zh) 2023-06-06

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