KR20220165747A - 표적 rna의 편집방법 - Google Patents

표적 rna의 편집방법 Download PDF

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KR20220165747A
KR20220165747A KR1020227037296A KR20227037296A KR20220165747A KR 20220165747 A KR20220165747 A KR 20220165747A KR 1020227037296 A KR1020227037296 A KR 1020227037296A KR 20227037296 A KR20227037296 A KR 20227037296A KR 20220165747 A KR20220165747 A KR 20220165747A
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미즈호 이치노세
베르나드 구트만
유스케 야지
유미 아카이와
야스카 시마지리
타카히로 나카무라
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에딧포스 인코포레이티드
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KR1020227037296A 2020-03-31 2021-03-31 표적 rna의 편집방법 Pending KR20220165747A (ko)

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JPJP-P-2020-065065 2020-03-31
JP2020065065 2020-03-31
PCT/JP2021/014096 WO2021201198A1 (ja) 2020-03-31 2021-03-31 標的ｒｎａを編集する方法

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US (1) US20230125942A1 (https=)
EP (1) EP4130274A4 (https=)
JP (4) JP7668547B2 (https=)
KR (1) KR20220165747A (https=)
CN (1) CN115698296A (https=)
AU (1) AU2021248204A1 (https=)
BR (1) BR112022019571A2 (https=)
CA (1) CA3179365A1 (https=)
IL (1) IL296955A (https=)
TW (1) TWI899197B (https=)
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Publication number Priority date Publication date Assignee Title
CA3216313A1 (en) * 2021-04-30 2022-11-03 Masayuki NAKAMORI Myotonic dystrophy type 1 therapeutic drug
US20250302993A1 (en) * 2021-12-24 2025-10-02 GeCoRT Co., Ltd. Enzyme, complex, recombinant vector, therapeutic agent for genetic disorder, and polynucleotide
WO2024249445A2 (en) * 2023-05-26 2024-12-05 The Trustees Of Columbia University In The City Of New York An rna recognition and editing code of pentatricopeptide repeat proteins
CN117384884B (zh) * 2023-11-30 2024-03-08 辉大(上海)生物科技有限公司 IscB多肽及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013058404A1 (ja) 2011-10-21 2013-04-25 国立大学法人九州大学 Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用
WO2014175284A1 (ja) 2013-04-22 2014-10-30 国立大学法人九州大学 Ｐｐｒモチーフを利用したｄｎａ結合性タンパク質およびその利用

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EP2336332A3 (en) * 2008-04-29 2011-11-09 Monsanto Technology LLC Genes and uses for plant enhancement

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013058404A1 (ja) 2011-10-21 2013-04-25 国立大学法人九州大学 Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用
WO2014175284A1 (ja) 2013-04-22 2014-10-30 国立大学法人九州大学 Ｐｐｒモチーフを利用したｄｎａ結合性タンパク質およびその利用

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
[비특허문헌 1] Lurin, C., Andres, C., Aubourg, S., Bellaoui, M., Bitton, F., Bruyere, C., Caboche, M., Debast, C., Gualberto, J., Hoffmann, B., et al.(2004). Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis. Plant Cell 16:2089-2103.
[비특허문헌 10] Gerke, P., Szovenyi, P., Neubauer, A., Lenz, H., Gutmann, B., McDowell, R., Small, I., Schallenberg-Rudinger, M., and Knoop, V.(2020). Towards a plant model for enigmatic U-to-C RNA editing:the organelle genomes, transcriptomes, editomes and candidate RNA editing factors in the hornwort Anthoceros agrestis. New Phytologist 225:1974-1992.
[비특허문헌 11] Gutmann B., Royan S., Schallenberg-Rudinger M., Lenz H., Castleden IR, McDowell R., Vacher MA, Tonti-Filippini J., Bond CS, Knoop V., and Small ID(2020). The Expansion and Diversification of Pentatricopeptide Repeat RNA-Editing Factors in Plants. Molecular Plant 13:215-230
[비특허문헌 12] Oldenkott, B., Yang, Y., Lesch, E., Knoop, V., and Schallenberg-Rudinger, M.(2019). Plant-type pentatricopeptide repeat proteins with a DYW domain drive C-to-U RNA editing in Escherichia coli. Communications Biology 2:85.
[비특허문헌 2] Cheng, S., Gutmann, B., Zhong, X., Ye, Y., Fisher, M. F., Bai, F., Castleden, I., Song, Y., Song, B., Huang, J., et al.(2016). Redefining the structural motifs that determine RNA binding and RNA editing by pentatricopeptide repeat proteins in land plants. Plant J. 85:532-547.
[비특허문헌 3] Barkan, A., Rojas, M., Fujii, S., Yap, A., Chong, Y. S., Bond, C. S., and Small, I.(2012). A combinatorial amino acid code for RNA recognition by pentatricopeptide repeat proteins. PLoS Genet. 8:e1002910.
[비특허문헌 4] Shen, C., Zhang, D., Guan, Z., Liu, Y., Yang, Z., Yang, Y., Wang, X., Wang, Q. Zhang, Q. Fan, S., et al.(2016). Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins. Nat. Commun. 7:11285.
[비특허문헌 5] Yagi, Y., Hayashi, S., Kobayashi, K., Hirayama, T., and Nakamura, T.(2013). Elucidation of the RNA recognition code for pentatricopeptide repeat proteins involved in organelle RNA editing in plants. PLoS One 8:e57286.
[비특허문헌 6] Kobayashi, T., Yagi, Y., and Nakamura, T.(2019). Comprehensive Prediction of Target RNA Editing Sites for PLS-Class PPR Proteins in Arabidopsis thaliana. Plant Cell Physiol. 60:862-874.
[비특허문헌 7] Yan, J., Yao, Y., Hong, S., Yang, Y., Shen, C., Zhang, Q. Zhang, D., Zou, T., and Yin, P.(2019). Delineation of pentatricopeptide repeat codes for target RNA prediction. Nucleic Acids Res. 47:3728-3738.
[비특허문헌 8] Takenaka, M., Zehrmann, A., Brennicke, A., and Graichen, K.(2013). Improved computational target site prediction for pentatricopeptide repeat RNA editing factors. PLoS One 8:e65343.
[비특허문헌 9] Knie, N., Grewe, F., Fischer, S., and Knoop, V.(2016). Reverse U-to-C editing exceeds C-to-U RNA editing in some ferns-a monilophyte-wide comparison of chloroplast and mitochondrial RNA editing suggests independent evolution of the two processes in both organelles. BMC Evol. Biol. 16:134.

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CN115698296A (zh) 2023-02-03
JP7668547B2 (ja) 2025-04-25
US20230125942A1 (en) 2023-04-27
JP2025120313A (ja) 2025-08-15
CA3179365A1 (en) 2021-10-07
WO2021201198A1 (ja) 2021-10-07
JP7698351B2 (ja) 2025-06-25
BR112022019571A2 (pt) 2022-12-06
EP4130274A4 (en) 2024-05-22
IL296955A (en) 2022-12-01
EP4130274A1 (en) 2023-02-08
JP7698371B1 (ja) 2025-06-25
JP2025107239A (ja) 2025-07-17
TW202204382A (zh) 2022-02-01
JP2024096897A (ja) 2024-07-17
JPWO2021201198A1 (https=) 2021-10-07
TWI899197B (zh) 2025-10-01
AU2021248204A1 (en) 2022-11-10

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