JPWO2021201198A1 - - Google Patents

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Publication number
JPWO2021201198A1
JPWO2021201198A1 JP2022512682A JP2022512682A JPWO2021201198A1 JP WO2021201198 A1 JPWO2021201198 A1 JP WO2021201198A1 JP 2022512682 A JP2022512682 A JP 2022512682A JP 2022512682 A JP2022512682 A JP 2022512682A JP WO2021201198 A1 JPWO2021201198 A1 JP WO2021201198A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2022512682A
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Japanese (ja)
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JP7668547B2 (ja
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Publication of JPWO2021201198A1 publication Critical patent/JPWO2021201198A1/ja
Priority to JP2024065910A priority Critical patent/JP7698351B2/ja
Application granted granted Critical
Priority to JP2025073407A priority patent/JP7698371B1/ja
Publication of JP7668547B2 publication Critical patent/JP7668547B2/ja
Priority to JP2025094806A priority patent/JP2025120313A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
JP2022512682A 2020-03-31 2021-03-31 標的rnaを編集する方法 Active JP7668547B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2024065910A JP7698351B2 (ja) 2020-03-31 2024-04-16 標的rnaを編集する方法
JP2025073407A JP7698371B1 (ja) 2020-03-31 2025-04-25 標的rnaを編集する方法
JP2025094806A JP2025120313A (ja) 2020-03-31 2025-06-06 標的rnaを編集する方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020065065 2020-03-31
JP2020065065 2020-03-31
PCT/JP2021/014096 WO2021201198A1 (ja) 2020-03-31 2021-03-31 標的rnaを編集する方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024065910A Division JP7698351B2 (ja) 2020-03-31 2024-04-16 標的rnaを編集する方法

Publications (2)

Publication Number Publication Date
JPWO2021201198A1 true JPWO2021201198A1 (https=) 2021-10-07
JP7668547B2 JP7668547B2 (ja) 2025-04-25

Family

ID=77930108

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2022512682A Active JP7668547B2 (ja) 2020-03-31 2021-03-31 標的rnaを編集する方法
JP2024065910A Active JP7698351B2 (ja) 2020-03-31 2024-04-16 標的rnaを編集する方法
JP2025073407A Active JP7698371B1 (ja) 2020-03-31 2025-04-25 標的rnaを編集する方法
JP2025094806A Pending JP2025120313A (ja) 2020-03-31 2025-06-06 標的rnaを編集する方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2024065910A Active JP7698351B2 (ja) 2020-03-31 2024-04-16 標的rnaを編集する方法
JP2025073407A Active JP7698371B1 (ja) 2020-03-31 2025-04-25 標的rnaを編集する方法
JP2025094806A Pending JP2025120313A (ja) 2020-03-31 2025-06-06 標的rnaを編集する方法

Country Status (11)

Country Link
US (1) US20230125942A1 (https=)
EP (1) EP4130274A4 (https=)
JP (4) JP7668547B2 (https=)
KR (1) KR20220165747A (https=)
CN (1) CN115698296A (https=)
AU (1) AU2021248204A1 (https=)
BR (1) BR112022019571A2 (https=)
CA (1) CA3179365A1 (https=)
IL (1) IL296955A (https=)
TW (1) TWI899197B (https=)
WO (1) WO2021201198A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3216313A1 (en) * 2021-04-30 2022-11-03 Masayuki NAKAMORI Myotonic dystrophy type 1 therapeutic drug
JPWO2023120658A1 (https=) * 2021-12-24 2023-06-29
WO2024249445A2 (en) * 2023-05-26 2024-12-05 The Trustees Of Columbia University In The City Of New York An rna recognition and editing code of pentatricopeptide repeat proteins
CN117384884B (zh) * 2023-11-30 2024-03-08 辉大(上海)生物科技有限公司 IscB多肽及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009134339A2 (en) * 2008-04-29 2009-11-05 Monsanto Technology, Llc Genes and uses for plant enhancement
DK2784157T3 (da) * 2011-10-21 2019-10-21 Univ Kyushu Nat Univ Corp Designfremgangsmåde til et rna-bindende protein under anvendelse af ppr-motiv og anvendelse deraf
AU2014258386B2 (en) 2013-04-22 2018-10-25 Hiroshima University DNA binding protein using PPR motif, and use thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
COMMUNICATION BIOLOGY, vol. 2, no. 85, JPN6023028543, 2019, pages 1 - 8, ISSN: 0005238932 *
DATABASE GENBANK, ACCESSION NO.EFJ215522, ENTRY VERSION 1 [ONLINE], JPN6023028545, 25 June 2016 (2016-06-25), pages 2023 - 6, ISSN: 0005238930 *
DATABASE GENBANK, ACCESSION NO.EU495537, ENTRY VERSION 1 [ONLINE], JPN6023028544, 26 June 2016 (2016-06-26), pages 2023 - 6, ISSN: 0005238931 *
MOL. BIOL. EVOL., vol. 25, no. 7, JPN6024000289, 2008, pages 1405 - 1414, ISSN: 0005238933 *
NEW PHYTOLOGIST, vol. 225, no. 5, JPN6024037712, March 2020 (2020-03-01), pages 1974 - 1992, ISSN: 0005416582 *

Also Published As

Publication number Publication date
JP7668547B2 (ja) 2025-04-25
JP7698371B1 (ja) 2025-06-25
JP2025120313A (ja) 2025-08-15
IL296955A (en) 2022-12-01
EP4130274A1 (en) 2023-02-08
CA3179365A1 (en) 2021-10-07
TW202204382A (zh) 2022-02-01
JP2024096897A (ja) 2024-07-17
WO2021201198A1 (ja) 2021-10-07
EP4130274A4 (en) 2024-05-22
JP2025107239A (ja) 2025-07-17
AU2021248204A1 (en) 2022-11-10
US20230125942A1 (en) 2023-04-27
TWI899197B (zh) 2025-10-01
JP7698351B2 (ja) 2025-06-25
BR112022019571A2 (pt) 2022-12-06
CN115698296A (zh) 2023-02-03
KR20220165747A (ko) 2022-12-15

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