KR20220157515A - Liv1-adc와 화학요법제를 사용한 병용 요법 - Google Patents
Liv1-adc와 화학요법제를 사용한 병용 요법 Download PDFInfo
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- KR20220157515A KR20220157515A KR1020227039721A KR20227039721A KR20220157515A KR 20220157515 A KR20220157515 A KR 20220157515A KR 1020227039721 A KR1020227039721 A KR 1020227039721A KR 20227039721 A KR20227039721 A KR 20227039721A KR 20220157515 A KR20220157515 A KR 20220157515A
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
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- Dermatology (AREA)
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- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
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|---|---|---|---|
| KR1020237041743A KR20230169462A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 체크포인트 억제제를 사용한 병용 요법 |
Applications Claiming Priority (8)
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| US201662308639P | 2016-03-15 | 2016-03-15 | |
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| US201662317792P | 2016-04-04 | 2016-04-04 | |
| US62/317,792 | 2016-04-04 | ||
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| KR1020187028273A KR20180121571A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 화학요법제를 사용한 병용 요법 |
| PCT/US2017/022541 WO2017161007A1 (en) | 2016-03-15 | 2017-03-15 | Combination therapy using a liv1-adc and a chemotherapeutic |
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| KR1020187028273A Division KR20180121571A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 화학요법제를 사용한 병용 요법 |
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| KR1020237041743A Division KR20230169462A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 체크포인트 억제제를 사용한 병용 요법 |
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| KR1020227039721A Ceased KR20220157515A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 화학요법제를 사용한 병용 요법 |
| KR1020187028273A Ceased KR20180121571A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 화학요법제를 사용한 병용 요법 |
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| KR1020237041743A Withdrawn KR20230169462A (ko) | 2016-03-15 | 2017-03-15 | Liv1-adc와 체크포인트 억제제를 사용한 병용 요법 |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2819038C (en) | 2010-12-06 | 2023-10-17 | Seattle Genetics, Inc. | Humanized antibodies to liv-1 and use of same to treat cancer |
| US20200283540A1 (en) * | 2017-12-01 | 2020-09-10 | Seattle Genetics, Inc. | Humanized anti-liv1 antibodies for the treatment of breast cancer |
| JP7471289B2 (ja) * | 2018-11-07 | 2024-04-19 | クリスパー セラピューティクス アクチェンゲゼルシャフト | 抗liv1免疫細胞癌療法 |
| CA3164124A1 (en) | 2019-12-09 | 2021-06-17 | Seagen Inc. | Combination therapy with liv1-adc and pd-1 antagonist |
| AU2021349385A1 (en) * | 2020-09-28 | 2023-05-25 | Seagen Inc. | Humanized anti-liv1 antibodies for the treatment of cancer |
| US12036286B2 (en) | 2021-03-18 | 2024-07-16 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| WO2024188339A1 (zh) * | 2023-03-15 | 2024-09-19 | 浙江博锐生物制药有限公司 | 抗liv-1抗体和抗liv-1抗体药物偶联物及其药物用途 |
| WO2025162207A1 (zh) * | 2024-01-31 | 2025-08-07 | 上海复宏汉霖生物技术股份有限公司 | 抗liv1抗体及使用方法 |
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Also Published As
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| MX2023008849A (es) | 2023-08-15 |
| US20190085091A1 (en) | 2019-03-21 |
| KR20230169462A (ko) | 2023-12-15 |
| CN108697801A (zh) | 2018-10-23 |
| JP2022058676A (ja) | 2022-04-12 |
| MA45324A (fr) | 2019-01-23 |
| WO2017161007A1 (en) | 2017-09-21 |
| MX2018010847A (es) | 2019-07-04 |
| AU2017235545A1 (en) | 2018-10-25 |
| US20230235083A1 (en) | 2023-07-27 |
| EA201891968A1 (ru) | 2019-02-28 |
| US11325980B2 (en) | 2022-05-10 |
| JP2024075639A (ja) | 2024-06-04 |
| JP2019508433A (ja) | 2019-03-28 |
| AU2024201856A1 (en) | 2024-04-11 |
| SG11201807526SA (en) | 2018-09-27 |
| BR112018068129A2 (pt) | 2019-01-15 |
| CA3016485A1 (en) | 2017-09-21 |
| EP3429626A1 (en) | 2019-01-23 |
| EP3429626A4 (en) | 2020-05-06 |
| IL261505A (en) | 2018-10-31 |
| SG10201912908QA (en) | 2020-02-27 |
| KR20180121571A (ko) | 2018-11-07 |
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