KR20220140527A - 치료용 기체 충전 미세소포 - Google Patents

치료용 기체 충전 미세소포 Download PDF

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Publication number
KR20220140527A
KR20220140527A KR1020227028178A KR20227028178A KR20220140527A KR 20220140527 A KR20220140527 A KR 20220140527A KR 1020227028178 A KR1020227028178 A KR 1020227028178A KR 20227028178 A KR20227028178 A KR 20227028178A KR 20220140527 A KR20220140527 A KR 20220140527A
Authority
KR
South Korea
Prior art keywords
suspension
microvesicles
gas
administered
filled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020227028178A
Other languages
English (en)
Korean (ko)
Inventor
빅터 장노트
알렉상드르 헬베르트
Original Assignee
브라코 스위스 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 브라코 스위스 에스.에이. filed Critical 브라코 스위스 에스.에이.
Publication of KR20220140527A publication Critical patent/KR20220140527A/ko
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020227028178A 2020-02-11 2021-02-10 치료용 기체 충전 미세소포 Pending KR20220140527A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062975005P 2020-02-11 2020-02-11
US62/975,005 2020-02-11
PCT/EP2021/053183 WO2021160659A1 (en) 2020-02-11 2021-02-10 Gas-filled microvesicles for therapeutic use

Publications (1)

Publication Number Publication Date
KR20220140527A true KR20220140527A (ko) 2022-10-18

Family

ID=74625954

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227028178A Pending KR20220140527A (ko) 2020-02-11 2021-02-10 치료용 기체 충전 미세소포

Country Status (7)

Country Link
US (1) US20230057224A1 (https=)
EP (1) EP4103152B1 (https=)
JP (1) JP7743415B2 (https=)
KR (1) KR20220140527A (https=)
CN (1) CN115103667A (https=)
CA (1) CA3165200A1 (https=)
WO (1) WO2021160659A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
CA2748995C (en) * 2008-10-07 2018-01-16 Bracco Suisse Sa Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
EP2934740B1 (en) * 2012-12-21 2019-12-11 Bracco Suisse SA Gas-filled microvesicles
EP3233136B8 (en) * 2014-12-18 2019-04-10 Bracco Suisse SA Targeted gas-filled microvesicles formulation
CN107206065A (zh) * 2014-12-22 2017-09-26 博莱科瑞士股份有限公司 用作疫苗的气体填充的微囊

Also Published As

Publication number Publication date
EP4103152B1 (en) 2025-07-23
CN115103667A (zh) 2022-09-23
WO2021160659A1 (en) 2021-08-19
US20230057224A1 (en) 2023-02-23
JP2023512943A (ja) 2023-03-30
EP4103152A1 (en) 2022-12-21
JP7743415B2 (ja) 2025-09-24
CA3165200A1 (en) 2021-08-19
EP4103152C0 (en) 2025-07-23

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Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000