JP7743415B2 - 治療的使用のためのガス充填微小胞 - Google Patents

治療的使用のためのガス充填微小胞

Info

Publication number
JP7743415B2
JP7743415B2 JP2022544054A JP2022544054A JP7743415B2 JP 7743415 B2 JP7743415 B2 JP 7743415B2 JP 2022544054 A JP2022544054 A JP 2022544054A JP 2022544054 A JP2022544054 A JP 2022544054A JP 7743415 B2 JP7743415 B2 JP 7743415B2
Authority
JP
Japan
Prior art keywords
suspension
gas
microvesicles
minutes
filled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022544054A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023512943A5 (https=
JPWO2021160659A5 (https=
JP2023512943A (ja
Inventor
ヴィクター ジーンノット
アレクサンダー ヘルバート
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Suisse SA
Original Assignee
Bracco Suisse SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Suisse SA filed Critical Bracco Suisse SA
Publication of JP2023512943A publication Critical patent/JP2023512943A/ja
Publication of JP2023512943A5 publication Critical patent/JP2023512943A5/ja
Publication of JPWO2021160659A5 publication Critical patent/JPWO2021160659A5/ja
Application granted granted Critical
Publication of JP7743415B2 publication Critical patent/JP7743415B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022544054A 2020-02-11 2021-02-10 治療的使用のためのガス充填微小胞 Active JP7743415B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062975005P 2020-02-11 2020-02-11
US62/975,005 2020-02-11
PCT/EP2021/053183 WO2021160659A1 (en) 2020-02-11 2021-02-10 Gas-filled microvesicles for therapeutic use

Publications (4)

Publication Number Publication Date
JP2023512943A JP2023512943A (ja) 2023-03-30
JP2023512943A5 JP2023512943A5 (https=) 2024-02-15
JPWO2021160659A5 JPWO2021160659A5 (https=) 2024-02-15
JP7743415B2 true JP7743415B2 (ja) 2025-09-24

Family

ID=74625954

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022544054A Active JP7743415B2 (ja) 2020-02-11 2021-02-10 治療的使用のためのガス充填微小胞

Country Status (7)

Country Link
US (1) US20230057224A1 (https=)
EP (1) EP4103152B1 (https=)
JP (1) JP7743415B2 (https=)
KR (1) KR20220140527A (https=)
CN (1) CN115103667A (https=)
CA (1) CA3165200A1 (https=)
WO (1) WO2021160659A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012505179A (ja) 2008-10-07 2012-03-01 ブラッコ・シュイス・ソシエテ・アノニム 抗ポリマー抗体およびそれと結合するリポソームまたは微小胞を含むターゲッティング構築物
JP2016503773A (ja) 2012-12-21 2016-02-08 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ガス封入マイクロベシクル
JP2017537907A (ja) 2014-12-22 2017-12-21 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ワクチンとしての使用のためのガス入りの微小胞
JP2018500294A (ja) 2014-12-18 2018-01-11 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ 標的化されたガス入りの微小胞の製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012505179A (ja) 2008-10-07 2012-03-01 ブラッコ・シュイス・ソシエテ・アノニム 抗ポリマー抗体およびそれと結合するリポソームまたは微小胞を含むターゲッティング構築物
JP2016503773A (ja) 2012-12-21 2016-02-08 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ガス封入マイクロベシクル
JP2018500294A (ja) 2014-12-18 2018-01-11 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ 標的化されたガス入りの微小胞の製剤
JP2017537907A (ja) 2014-12-22 2017-12-21 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ワクチンとしての使用のためのガス入りの微小胞

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Controlled Release，2016年，Vol.243，pp.172-181

Also Published As

Publication number Publication date
EP4103152B1 (en) 2025-07-23
KR20220140527A (ko) 2022-10-18
CN115103667A (zh) 2022-09-23
WO2021160659A1 (en) 2021-08-19
US20230057224A1 (en) 2023-02-23
JP2023512943A (ja) 2023-03-30
EP4103152A1 (en) 2022-12-21
CA3165200A1 (en) 2021-08-19
EP4103152C0 (en) 2025-07-23

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