KR20220124179A - 작은 화합물을 사용하는 ipsc 유래 이펙터 면역세포 강화 - Google Patents

작은 화합물을 사용하는 ipsc 유래 이펙터 면역세포 강화 Download PDF

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KR20220124179A
KR20220124179A KR1020227023102A KR20227023102A KR20220124179A KR 20220124179 A KR20220124179 A KR 20220124179A KR 1020227023102 A KR1020227023102 A KR 1020227023102A KR 20227023102 A KR20227023102 A KR 20227023102A KR 20220124179 A KR20220124179 A KR 20220124179A
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cell
cells
differentiated
receptor
immune
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Korean (ko)
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바흐람 발라메르
라이언 비요르달
조드 굿리지
밀리 만달
치아-웨이 창
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페이트 세러퓨틱스, 인코포레이티드
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KR1020227023102A 2019-12-06 2020-12-04 작은 화합물을 사용하는 ipsc 유래 이펙터 면역세포 강화 Pending KR20220124179A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962945040P 2019-12-06 2019-12-06
US62/945,040 2019-12-06
PCT/US2020/063457 WO2021113744A1 (en) 2019-12-06 2020-12-04 Enhancement of ipsc-derived effector immune cell using small compounds

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KR20220124179A true KR20220124179A (ko) 2022-09-13

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KR1020227023102A Pending KR20220124179A (ko) 2019-12-06 2020-12-04 작은 화합물을 사용하는 ipsc 유래 이펙터 면역세포 강화

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US (1) US20230016034A1 (https=)
EP (1) EP4069827A4 (https=)
JP (1) JP2023505206A (https=)
KR (1) KR20220124179A (https=)
CN (1) CN115087731A (https=)
AU (1) AU2020395239A1 (https=)
BR (1) BR112022011072A2 (https=)
CA (1) CA3160423A1 (https=)
IL (1) IL293564A (https=)
MX (1) MX2022006725A (https=)
WO (1) WO2021113744A1 (https=)

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US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
WO2022011065A1 (en) * 2020-07-07 2022-01-13 The Nemours Foundation Tumor-activated alloreactive and xenoreactive t cells and their use in immunotherapy against cancer
AR125851A1 (es) * 2021-05-12 2023-08-16 Crispr Therapeutics Ag Células inmunes modificadas genéticamente que se focalizan en cd70 para su uso en el tratamiento de neoplasias malignas hematopoyéticas
WO2022269393A1 (en) * 2021-06-23 2022-12-29 Crispr Therapeutics Ag Engineered cells with improved protection from natural killer cell killing
AU2022304599A1 (en) * 2021-07-02 2024-01-18 Fate Therapeutics, Inc. Protected effector cells and use thereof for allogeneic adoptive cell therapies
KR20240102994A (ko) * 2021-11-08 2024-07-03 페이트 세러퓨틱스, 인코포레이티드 고형 종양의 유비쿼터스 표적화를 향상시키는 조작된 이펙터 세포 및 방법
TW202340453A (zh) * 2022-01-28 2023-10-16 中國大陸商杭州啟函生物科技有限公司 用於基於細胞的免疫療法的方法和組合物
US20250222029A1 (en) 2022-04-08 2025-07-10 Fate Therapeutics, Inc. Chimeric antigen receptor for tumor targeting
US20250228943A1 (en) * 2022-04-08 2025-07-17 Fate Therapeutics, Inc. Cells having solid tumor targeting backbone and use thereof
WO2024097911A1 (en) * 2022-11-02 2024-05-10 Fate Therapeutics, Inc. Off-the-shelf therapeutic cells with multiplex genomic engineering for targeting gprc5d
WO2024102704A2 (en) * 2022-11-07 2024-05-16 Fate Therapeutics, Inc. Ipsc-derived nk cell targeting mica/b for solid tumor treatment
WO2025104248A1 (en) * 2023-11-17 2025-05-22 Repairon Immuno Gmbh Method of producing an immune cell devoid of endogenous effector functions from pluripotent stem cells
CN117305241B (zh) * 2023-11-28 2024-03-19 上海兴瑞一达生物科技有限公司 一种hiPSCs诱导分化为NK细胞的方法
WO2025217183A1 (en) * 2024-04-09 2025-10-16 Board Of Regents, The University Of Texas System Prepared natural killer cells and uses thereof
CN119220607B (zh) * 2024-12-03 2025-03-07 星奕昂(上海)生物科技有限公司 编辑tim3基因获得功能强化的car-nk细胞的方法与应用
CN121472143B (zh) * 2026-01-06 2026-03-31 南京医拓生物科技有限公司 高活化状态nk细胞富集型淋巴细胞的培养方法

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CA2992551A1 (en) * 2015-07-21 2017-01-26 Novartis Ag Methods for improving the efficacy and expansion of immune cells
WO2017025323A1 (en) * 2015-08-11 2017-02-16 Cellectis Cells for immunotherapy engineered for targeting cd38 antigen and for cd38 gene inactivation
KR20250141836A (ko) * 2015-11-04 2025-09-29 페이트 세러퓨틱스, 인코포레이티드 만능 세포의 유전자 조작
JP7653759B2 (ja) * 2016-01-20 2025-03-31 フェイト セラピューティクス，インコーポレイテッド 養子免疫療法における免疫細胞調節のための組成物および方法
US20190037831A1 (en) * 2016-02-01 2019-02-07 Green Cross Lab Cell Corporation Medium composition for cryopreservation of cell and use thereof
CN118948892A (zh) * 2017-05-01 2024-11-15 朱诺治疗学股份有限公司 细胞疗法与免疫调节化合物的组合
JP2020528885A (ja) * 2017-07-19 2020-10-01 フェイト セラピューティクス，インコーポレイテッド 養子免疫療法における免疫細胞調節のための組成物および方法
JP2021505131A (ja) * 2017-12-08 2021-02-18 フェイト セラピューティクス，インコーポレイテッド 増強されたｉＰＳＣ由来のエフェクター細胞を用いた免疫療法
TW202020145A (zh) * 2018-07-13 2020-06-01 國立大學法人京都大學 γδＴ細胞的製造方法

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AU2020395239A1 (en) 2022-06-23
JP2023505206A (ja) 2023-02-08
EP4069827A4 (en) 2024-05-29
CA3160423A1 (en) 2021-06-10
CN115087731A (zh) 2022-09-20
EP4069827A1 (en) 2022-10-12
BR112022011072A2 (pt) 2022-08-23
US20230016034A1 (en) 2023-01-19
WO2021113744A1 (en) 2021-06-10
MX2022006725A (es) 2022-08-22
IL293564A (en) 2022-08-01

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