KR20220097627A - a woman's genital cleaner - Google Patents

a woman's genital cleaner Download PDF

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Publication number
KR20220097627A
KR20220097627A KR1020200187581A KR20200187581A KR20220097627A KR 20220097627 A KR20220097627 A KR 20220097627A KR 1020200187581 A KR1020200187581 A KR 1020200187581A KR 20200187581 A KR20200187581 A KR 20200187581A KR 20220097627 A KR20220097627 A KR 20220097627A
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composition
preventing
silver
female genital
copper
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KR1020200187581A
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Korean (ko)
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김선미
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김선미
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Publication of KR20220097627A publication Critical patent/KR20220097627A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present invention relates to a composition for preventing and alleviating female genital diseases which is the composition containing silver or copper as an active component for preventing and alleviating female genital diseases, and further containing one or more of vegetable extracts including Torilis japonica, Schisandra chinensis, and Pseudocydonia sinensis. The composition has functions of sterilization, deodorization, and drying prevention function of the vaginal cavity, thereby having effects of preventing, alleviating, and deodorizing female genital internal and external diseases.

Description

여성 생식기의 질병 예방 및 개선제 조성물{a woman's genital cleaner}A composition for preventing and improving female genital diseases {a woman's genital cleaner}

본 발명은 여성 생식기 질병의 예방 및 개선제 조성물에 관한 것으로, 더욱 상세하게는 탈취 및 살균, 세포재생을 포함하는 질병의 예방 및 개선 유효성분으로 은 또는 구리중 어느 한 물질를 함유하는 식물성 추출물이 포함된 여성 생식기 질병 예방 및 개선제 조성물 에 관한 것이다.The present invention relates to a composition for preventing and ameliorating female genital diseases, and more particularly, containing a plant extract containing either silver or copper as an active ingredient for preventing and improving diseases including deodorization and sterilization and cell regeneration. It relates to a composition for preventing and ameliorating female genital diseases.

여성의 성기는 여성 생식기관으로 자궁(unterus)은 자궁외막과 자궁내막사이 자궁근체, 근층. 상기 근층인 자궁체에 감싸여 자궁강이 형성되어 있고, 이에 연결되어 자궁각, 자궁관, 자궁저, 난소와 인대, 난소제삭 그리고 자궁경관, 자궁경부, 질원개. 상기 질원개에 연결되어 질관(vagina)이 외부와 소통되게 연결되어 있다.A woman's genitals are the female reproductive organs. The uterine cavity is formed by being wrapped in the muscular layer, the uterine body, and connected thereto, the uterine horn, the uterine tube, the uterus, the ovaries and ligaments, the ovarian ablation, and the cervix, the cervix, and the vaginal fornix. It is connected to the forelimb vaginal tube (vagina) is connected to communicate with the outside.

또한 질 입구 주변은 대음순. 소음순. 뇨관 등으로 형성된 복잡한 기관이다.Also, the labia majora around the entrance to the vagina. noise order. It is a complex organ formed by the ureters, etc.

또한 해부학적 구조로 볼 때 상기 생식기관은 외부와 소통되는 기관은 질관(질강)을 통하게 되어 있고, 뇨관, 직장관 등이 인접하여 병변이 상호 영향을 미치게 되어 있다.In addition, in terms of anatomical structure, the organs communicating with the outside of the reproductive organs are through the vaginal canal (vaginal cavity), and the ureters, rectal tubes, etc. are adjacent to each other so that the lesions influence each other.

생식기 각 부위의 질환은 여러 원인에 의하여 발생되지만 특히 미생물 감염의 영향이 제일 크다. 상기 미생물의 영향으로 자궁의 경부세포에 변이세포가 발생될 수 있다.Diseases of each part of the genital organs are caused by various causes, but microbial infection is the most affected. Mutant cells may be generated in cervical cells of the uterus under the influence of the microorganism.

또한 배변 기관과 인접되어 있어 서로 상호 감염될 수도 있다.Also, since they are adjacent to the excretory organs, they may be cross-infected with each other.

이에 여성 생식기의 질병을 예방 또는 질병을 개선시키기 위한 노력으로 많은 연구가 이루어 지고 있다.Accordingly, many studies are being conducted in an effort to prevent or improve diseases of the female reproductive system.

이에 질내 불순물 배출을 위한 세정제, 또는 동시에 질내 혈액순환을 촉진시켜 질세포의 항노화 효과를 기대하는 세정제들에 대하여 많은 연구가 진행되고 있다할 것이나, 화장품류 재료를 사용하므로 자극성 화학물질이 포함되어 부작용이 발생될 수 있고, 질병의 개선에 대한 효과는 기대할 수준에 미치지 못한다.Therefore, it is said that a lot of research is being conducted on cleaning agents for discharging impurities in the vagina or cleaning agents that are expected to have an anti-aging effect on vaginal cells by promoting blood circulation in the vagina at the same time. Side effects may occur, and the effect on the improvement of the disease does not reach the expected level.

이러한 효과를 얻고자 천연물를 이용하여 조성된 질세정제는, 예를 들어 대한민국 등록특허 공보 10-0646593호에 공보된 상황버섯 추출물과 젓산배합 조성물를 유효성분으로 포함하는 질내 염증 및 자궁경부암 예방 및 치료용 조성물이 개시되어 있다. 또한 대한민국 등록특허공보 10-1920749호에서는 어성초 추출물를 비롯한 일정의 천연물 추출물로 제조한 조성물를 통하여 효과를 기대하고 있다. 또한 공개특허공보 10-2020-0117409에 의하면 마늘과 인삼, 석류를 포함하는 발효액을 세정제로 제시하고 있다.In order to obtain this effect, a vaginal cleanser formulated using a natural product is a composition for preventing and treating vaginal inflammation and cervical cancer, including, for example, the Sanghwang mushroom extract and lactic acid combination composition disclosed in Korean Patent Publication No. 10-0646593 as active ingredients. This is disclosed. In addition, in Korean Patent Publication No. 10-1920749, an effect is expected through a composition prepared with a certain natural extract, including eoseongcho extract. In addition, according to Laid-Open Patent Publication No. 10-2020-0117409, a fermented broth containing garlic, ginseng, and pomegranate is presented as a detergent.

상기와 같은 일정의 추출물로 제조된 조성물은 세정에 관한 기대에는 어느 정도 부합될 수 있을 것이나 미생물의 작용에 관한 질병의 개선과 이에 발생되는 악취에는 큰 영향을 기대 할 수 없다.The composition prepared from the extract as described above may meet the expectations regarding cleaning to some extent, but it cannot be expected to have a significant effect on the improvement of diseases related to the action of microorganisms and the odor generated therefrom.

대한민국 등록특허공보 10-1920749호Republic of Korea Patent Publication No. 10-1920749 대한민국 등록특허공보 10-0646593호Republic of Korea Patent Publication No. 10-0646593 대한민국 등록특허공보 10-1235370호Republic of Korea Patent Publication No. 10-1235370

본 발명은 상기와 같은 종래기술를 감안하여 안출된 것으로, 은 또는 구리의 효능과 기능성 식물의 효능을 이용하여 여성 성기내 미생물 친입을 방지하고, 질내 또는 경부에 친입한 미생물를 살균하고, 미생물에 의한 부페로 발생하는 악취의 발생을 방지 또는 발생된 악취를 제어하며, 성기 기관인 질강 세포의 보습유지로 질세포의 건조를 방지하여 질 세포의 손상을 예방하고, 손상된 세포를 재생하며 미생물에 의한 세포의 변이를 제어 할 수 있는 여성 생식기 질병의 예방 및 개선제 조성물 제공을 목적으로 한다.The present invention has been devised in view of the prior art as described above, and by using the efficacy of silver or copper and the efficacy of functional plants, it prevents the entry of microorganisms into the female genital tract, sterilizes microorganisms that have entered the vagina or cervix, and serves as a buffet by microorganisms Prevents the occurrence of odors caused by or controls the generated odors, prevents the drying of vaginal cells by maintaining moisture in the vaginal cavity cells, which are the genital organs, and prevents damage to vaginal cells, regenerates damaged cells, and mutations of cells by microorganisms An object of the present invention is to provide a composition for preventing and improving female genital diseases that can control

상기와 같은 과제를 해결하기 위한 본 발명의 여성 생식기 질병의 예방 및 개선제 조성물은, 탈취 및 살균 유효성분으로 은 또는 구리를 함유하는 것을 특징으로 한다.The composition for preventing and improving female genital diseases of the present invention for solving the above problems is characterized in that it contains silver or copper as a deodorizing and sterilizing active ingredient.

또한 사상자를 포함하는 기능성 식물의 혼합 추출물를 포함시켜 여성 생식기의 질별 예방 및 개선의 효과를 증대시키는 것을 특징으로 한다.In addition, it is characterized in that it increases the effect of preventing and improving the quality of female genital organs by including a mixed extract of functional plants including casualties.

이때 사상자를 포함하는 상기 식물성 추출물은, 열수 추출물 또는 분획물 중 선택하여 사용될 수 있다.In this case, the vegetable extract including the casualties may be selected from hot water extracts or fractions.

상기 유효물질인 은 또는 구리는 콜로이달 용액 또는 이온수(Ag+또는 Cu+), 나노 형태로 함유될 수 있고, 바람직하게는 은 또는 구리의 형태는 이온수(Ag+또는 Cu+)인 것이다.The active material, silver or copper, may be contained in a colloidal solution or ionized water (Ag + or Cu + ), in nano form, and preferably silver or copper is in the form of ionized water (Ag + or Cu + ).

상기 은 또는 구리의 함유량은 세정과 질병의 개선 및 치료 등 이용 용도에 따라 그 함유량이 각각 다르다는 것에 주목해야 한다.It should be noted that the content of silver or copper is different depending on the intended use, such as cleaning and amelioration and treatment of diseases.

이에 따라 조성물 총량의 최저 0.0005%(5ppm)이상 0.25%(2500PPM) 함유 될 수도 있다.Accordingly, it may contain at least 0.0005% (5ppm) or 0.25% (2500ppm) of the total amount of the composition.

또한 상기 여성 조성물은 풀빅산 또는 유기 개르마늄이 포함되어 조성될 수 있다.In addition, the female composition may include fulvic acid or organic germanium.

또한 여성 질를 포함하는 여성 성기 세포의 보습유지를 위하여 보습물질이 포함 될 수 있고, 질세포에 조성물의 유효성분을 흡수시키기 위하여 천연 흡수제 또는 흡수 촉진제로 나무로 부터 일출시킨 수액이 포함될 수 있다.In addition, a moisturizing material may be included to maintain moisture in female genital cells including the female vagina, and sap from a tree as a natural absorbent or absorption enhancer may be included in order to absorb the active ingredient of the composition into the vaginal cells.

또한 상기 조성물은 액체 또는 젤 형태 또는 정제 형태일 수 있다.In addition, the composition may be in liquid or gel form or tablet form.

또한 상기 조성물은 의료용 주사기 형태의 주입관에 충진되어 질내에 주입 시킬 수 있는 특징을 갖는다.In addition, the composition has a feature that can be injected into the vagina by filling the injection tube in the form of a medical syringe.

본 발명에 따른 조성물은 천연 방부 살균 물질인 무독, 무해한 광물질과 천연 식물로부터 추출한 항소양물질, 항염물질, 항암물질, 보습물질, 탈취물질로 조성되어 질의 청결과 질병을 예방 및 개선하는 효과가 있다.The composition according to the present invention is composed of non-toxic and harmless minerals, which are natural preservatives and sterilizing substances, and anti-inflammatory substances, anti-inflammatory substances, anti-cancer substances, moisturizing substances, and deodorizing substances extracted from natural plants, thereby preventing and improving vaginal cleanliness and diseases. .

이하 본 발명을 보다 상세히 설명한다. 본 명세서 및 청구범위에 사용된 용어나 단어는 통상적이거나 사전적인 의미로 한정해서 해석되어서는 아니되며, 발명자는 그 자신의 발명을 가장 최선의 방법으로 설명하기 위해 용어의 개념을 적적하게 정의할 수 있다는 원측에 입각하여 본 발명의 기술적 사상에 부합하는 의미와 개념으로 해석되어야만 한다.Hereinafter, the present invention will be described in more detail. The terms or words used in the present specification and claims should not be construed as being limited to their ordinary or dictionary meanings, and the inventor may properly define the concept of the term in order to best describe his invention. It should be interpreted as meaning and concept consistent with the technical idea of the present invention based on the original side.

본 발명에 따른 여성 생식기내 질병 예방 및 개선 조성물은 탈취 및 살균 유효 물질로서 용액(콜로이달) 또는 이온수 또는 나노형태로 제조된 은 또는 구리가 조성물 총 중량에 0.001%이상 함유되는 것을 특징으로 한다.The composition for preventing and improving diseases in female reproductive organs according to the present invention is characterized in that, as a deodorizing and sterilizing effective material, silver or copper prepared in solution (colloidal) or ionized water or nano form is contained in the total weight of the composition by 0.001% or more.

또한 여성 생식기내 질병 예방 및 개선 조성물은 사상자를 포함하는 천연 식물들의 추출물에 은 또는 구리가 콜로이달 용액 형태 또는 이온수 형태 또는 나노입자 형태로 함유되어 있는 조성물인 것을 특징으로 한다.In addition, the composition for preventing and improving diseases in the female reproductive tract is a composition containing silver or copper in the form of a colloidal solution, ionized water, or nanoparticles in extracts of natural plants including casualties.

은은 예로부터 질병 예방을 위한 신비의 물질로 전해왔었고 650 여 가지의 병균을 박멸하는 효과를 가지고 있다는 것은 은의 살균효과를 인정하고 있다.Silver has been handed down as a mysterious substance for disease prevention since ancient times, and the fact that it has the effect of eradicating more than 650 kinds of germs acknowledges the sterilizing effect of silver.

동의보감에서는 " 은의 효능으로서 강한 살균력, 향균·향곰팡이, 인체내 호르몬계통의 균형을 유지해준다 또한 원적외선 방출, 음이온 방출로 냉대하와 같은 부인병 예방 및 치료에 효험이 있다,, 고 기술하고 있다.In Donguibogam, "Silver has strong sterilization power, antibacterial and antifungal properties, and it maintains the balance of hormones in the human body. Also, it is effective in preventing and treating gynecological diseases such as cold sores by emitting far-infrared rays and negative ions.

상기 천연 식물으로서 사상자를 포함하는 식물성 추출물은 고삼. 상백피. 후박, 오미자. 목과. 황기. 감초. 인동. 신이. 하고초. 토봉령. 만형자. 지실. 우방자. 목단피. 두충. 선인장(백년초, 천년초), 알로에, 호황련.. 구기자. 쇄양. 산약. 인삼, 삼백초, 병풀 무리 중 선택한 일종 이상의 혼합 식물의 추출물이며, 추출방법은 열수 또는 알코올추출 분획, 또는 발효 추출 중 어느 하나의 추출방법으로 추출한 물질로 구성된다.As the natural plant, the botanical extract containing the dead ginseng. white skin. Pumpkin, Omija. neck and. Astragalus. licorice. Indong. God. hagocho. Tobongyeong. man-made. Loss. ally. wood skin. headworm. Cactus (Baeknyeoncho, Cheonnyeoncho), aloe, chrysanthemum .. Goji berry. shunyang. acid medicine. It is an extract of one or more types of mixed plants selected from ginseng, ginseng, and Centella asiatica, and the extraction method consists of a material extracted by either extraction method of hot water or alcohol extraction fraction, or fermentation extraction.

상기 식물의 혼합 추출물은 조성물 총량의 5%-20%가 포함된다.The mixed extract of the plant contains 5%-20% of the total amount of the composition.

본 발명에서는 여성 생식기 질병 중 변이 세포의 발생을 고려하여 그 예방 및 개선의 차원에서 식물성 기능 물질를 선택한 것에 주목할 필요가 있다.In the present invention, it is worth paying attention to the fact that the plant functional material is selected in terms of prevention and improvement in consideration of the occurrence of mutated cells among female genital diseases.

실시를 위하여 상기 식물성 물질들 중 사상자, 오미자, 모과, 고삼, 상백피, 후박, 황기를 선택하였고, 선택한 물질에 대하여 그 효과를 알아본다.For the implementation, among the above plant substances, saengsaeng, omija, quince, ginseng, sangbaekpi, squash, and astragalus were selected, and the effects of the selected substances were investigated.

사상자casualties

사상자(Tolilis Japonica Decandolle)의 과실로서 항알러지 및 항 소양효과가 있다.As the fruit of Tolilis Japonica Decandolle, it has anti-allergic and anti-pruritic effects.

사상자 추출물을 이용하여 제1형 및 제4 알러지에 대하여 검토한 결과 다양한 알러지 모델에서 유의한 효과가 확인되어 있으며 주 성분은 oshol으로 항소양, 항암 작용을 갖는다.As a result of examining type 1 and type 4 allergy using the sasanqua extract, significant effects were confirmed in various allergy models.

참고문헌references

<Matsuda H. Tomohiro N. Ido Y. Kudo M Anti-allergic effects of cndii monnieri fructus (dried fruits of Cnidium monnieri) and its major component. ostohol. Bio Pharm Bull. 2002: 25: 809-12><Matsuda H. Tomohiro N. Ido Y. Kudo M Anti-allergic effects of cndii monnieri fructus (dried fruits of Cnidium monnieri) and its major component. osthol. Bio Pharm Bull. 2002: 25: 809-12>

고삼high ginseng

고삼은 콩과에 속하는 도둑놈의지팡이(Sophora flavescens Aiton)의 주피를 거의 벗긴 뿌리이다. 주성분은 알카로이드 1-2% 포함되어 있다. 항암효과가 있다.Old ginseng is the almost peeled root of the thief's stick (Sophora flavescens Aiton) belonging to the legume family. The main component contains 1-2% alkaloids. It has anticancer effect.

참고문헌references

<Yamaguchi- Miyamoto T. Kawasuji T. Kuraishi Y, Suzuki H. Antipruritic effects of Sophora flavescens on acute and chrnic itch-related responses in mice. Biol Pharm Bull 2003: 26: 722-4<Yamaguchi- Miyamoto T. Kawasuji T. Kuraishi Y, Suzuki H. Antipruritic effects of Sophora flavescens on acute and chrnic itch-related responses in mice. Biol Pharm Bull 2003: 26: 722-4

상백피sangbaekpi

상백피는 뽕나무(Morus alba Linne)의 근피를 말하며, Triterpenoid 계 화합물, Flavonoid 물질이 함유되어 있어 항암효과가 기대된다.Sangbaekpi refers to the root bark of Morus alba Linne, and contains triterpenoid compounds and flavonoid substances, so anti-cancer effects are expected.

참고문헌references

<Chang Im, woo WS Screening of Korean medicinal plants for antitumor activity. Arch. Pharm. Res. 1980:3: 75-78<Chang Im, woo WS Screening of Korean medicinal plants for antitumor activity. Arch. Pharm. Res. 1980:3: 75-78

후박humpback

후박(Magnolia officinalis Rehder et Wilson)은 후박나무의 수피이다. 주성분은 알카로이드 화합물로 magnocurarine 등과 폐닐계 화합물로 magnolol, honokiol등을 함유한다. 효과로는 항궤양효과와 honokiol에 의하여 혈관신생을 억제시켜 암의 발생 또는 성장을 저해 시키는 효과가 있다.Magnolia officinalis Rehder et Wilson (Magnolia officinalis Rehder et Wilson) is the bark of the spruce tree. The main component is an alkaloid compound, including magnocurarine, and phenolic compounds, including magnolol and honokiol. As an effect, it has the effect of inhibiting the occurrence or growth of cancer by inhibiting angiogenesis by anti-ulcer effect and honokiol.

목과(모과)quince (quince)

목과는 장미과(Rosaceae)에 속하는 모과나무의 열매이다. 성분은 Flavonoid 계열의 화합물이다. 염증반응 억제 효과와 항 소양작용을 한다.The quince family is the fruit of the quince tree belonging to the family Rosaceae. The component is a compound of the Flavonoid family. It has anti-inflammatory and anti-pruritic effects.

참고문헌references

<Oku H, Ueda Y, Ishiguro K. Antipuritic effects of the fruits of Chaenomeles sinensis. Biol Pharm Bull. 2003: 26: 1031-4.<Oku H, Ueda Y, Ishiguro K. Antipuritic effects of the fruits of Chaenomeles sinensis. Biol Pharm Bull. 2003: 26: 1031-4.

오미자Schisandra

오미자는 오미자과(Schizandraceae)에 속하는 열매이다. 자궁근에 대하여 oxytocin과 유사하게 자궁근의 리듬성 수축을 야기한다.Schisandra is a fruit belonging to the family Schizandraceae. Similar to oxytocin, it causes rhythmic contractions of the uterine muscle.

참고문헌references

<Zhu YP. Chinese Materia Medica Chemistry, Pharmacology and Applications. Hanwood Academic Pblishers, The Nethertands. Pp653-657.1998.<Zhu YP. Chinese Materia Medica Chemistry, Pharmacology and Applications. Hanwood Academic Pblishers, The Nethertands. Pp653-657.1998.

황기Astragalus

황기(RADIX ASTRAGALI)는 콩과에 속하는 다년생 초본인 단너삼 및 동속 근연 식물의 뿌리이다. 유효성분은 Fravonoid, Saponin, 점액질 셀레늄과 다종의 미네랄이 포함되어 있다. 기능은 말초 혈액 단구세포 증식을 통해 암세포에 대한 식균작용을 향상시키고 B세포의 IgG 생성능을 증가시키는 작용이 있으며 말초혈액단구에 (PBMC)의 종양괴사인자-알파(TNF-α)의 분비가 증가되는 효과도 있다.Astragalus (RADIX ASTRAGALI) is a perennial herb belonging to the legume family, and is the root of ginseng and closely related plants. Active ingredients include Fravonoid, Saponin, mucinous selenium and various minerals. The function is to improve phagocytosis on cancer cells through proliferation of peripheral blood monocytes, increase the ability of B cells to produce IgG, and increase the secretion of tumor necrosis factor-alpha (TNF-α) in peripheral blood monocytes (PBMC) It has the effect of being

참고문헌references

<Zhao KW. Kong HY. Effed of Asragalan on secretion of tumor necrosis factors in human peripheral blood mononuclear cells Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993: 13: 263-5.><Zhao KW. Kong HY. Effed of Asragalan on secretion of tumor necrosis factors in human peripheral blood mononuclear cells Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993: 13: 263-5.>

또한 본 발명의 조성물은 점도제가 포함될수 있으며, 이는 잔탄검, 하이셀, 카라기난. 카포머. 글루카메이트. 구아검. 세롤로오스(HEC). 전분. 한천. 우무. 녹말. 알긴산. 콜라겐. 펙틴 해조류, 알로에 추출물 중 어느 일종 이상이 조성물 총 중량에 겔형태 제조시1%-30% 정제 제조시 90%-95%포함될 수 있다.In addition, the composition of the present invention may contain a viscosity agent, which is xanthan gum, Hisel, carrageenan. capomer. glucamate. Guar Gum. Serolose (HEC). starch. agar. Woom. starch. alginic acid. Collagen. Any one or more of pectin seaweed and aloe extract may be included in the total weight of the composition by 1%-30% in gel form and 90%-95% in tablet preparation.

또한 성기 외음부 및 질강세포의 보습과 윤활을 목적으로 히알루론산이 총 중량에 0.1%-1%가 추가로 포함될 수 있고, 또한 다시마와 같은 해조류가 추가로 포함될수 있다. 질강내 손상된 세포 재생 목적으로 세포외기질(ECM)과 세포성장인자 , <EGF (Epidermal Growth Factor)>가 조성물 총중량에 각각 0.01% 추가하여 포함될 수 있다.In addition, for the purpose of moisturizing and lubricating the genital vulva and vaginal cavity cells, 0.1%-1% of hyaluronic acid may be additionally included in the total weight, and seaweed such as kelp may be additionally included. For the purpose of regenerating damaged cells in the vagina, extracellular matrix (ECM), cell growth factor, and <Epidermal Growth Factor (EGF)> may be included by adding 0.01% each to the total weight of the composition.

ECM (세포외기질, Extracellular matrix)이란 세포와 세포 사이의 틈을 메워 물리적으로 조직을 지지하거나 세포를 에워싸서 세포가 튼튼하게 살아가기 위한 환경을 조성하는 생체고분자의 집합체로 골격, 치아, 힘줄, 피부 등에 다량 포함되어 있다ECM (Extracellular matrix) is a collection of biopolymers that fill in the gaps between cells to physically support tissues or surround cells to create an environment for cells to live strongly. It is contained in large amounts in the skin, etc.

EGF(상피세포성장인자, Epidermal Growth Factor)란 사람의 몸속에 존재하는 상처치료 물질로 피부 등에 상처가 나면 혈액이나 땀, 침을 통해 공급되어 상처가 흉터 없이 자연적으로 아물게 하는 작용을 하는 단백질이다EGF (Epidermal Growth Factor) is a wound healing substance that exists in the human body. When there is a wound on the skin, it is supplied through blood, sweat, or saliva and is a protein that works to heal the wound naturally without scarring.

또한 본 원의 여성 생식기내 질병 예방 및 개선 조성물에 항암, 항산화, 유효물질 흡수 촉진, 해독, 세포재생, 항 미생물, 탈취를 목적으로 풀빅산을 함유시킬 수 있다.In addition, fulvic acid may be contained in the composition for preventing and improving diseases in the female reproductive system of the present application for the purpose of anticancer, antioxidant, promotion of absorption of active substances, detoxification, cell regeneration, antimicrobial, and deodorization.

또한 항산화 목적과 혈관내 노페물 제거로 혈행 개선을 위하여 유기 게르마늄이 추가되어 함유될 수 있다.In addition, organic germanium may be added for the purpose of antioxidant and to improve blood circulation by removing wastes in blood vessels.

이때 풀빅 또는 게르마늄의 함유량은 조성물 총 중량의 각각 0.0001%이상으로 함유될 수 있다In this case, the content of fulvic or germanium may be contained in each of 0.0001% or more of the total weight of the composition.

또한 여성 생식기내 질병 예방 및 개선제 조성물의 용매는 나무에서 일출한 수액 일 수 있다.In addition, the solvent of the composition for preventing and ameliorating diseases in the female reproductive tract may be sap from a tree.

상기 수액은 자작나무과 나무, 고로쇠나무, 물박달나무, 다래나무, 물푸레나무, 거제수나무, 사스레나무, 호두나무들과 덩굴식물로 수세미와 같은 독성이 없는 나무 및 덩굴식물에서 일출시킨 수액 일 수 있다.The sap may be a sap from a non-toxic tree and creeper such as a loofah, with birch trees, cypress trees, water birch trees, actinidia trees, ash trees, geoje trees, sassre trees, walnut trees and creepers. .

실시예Example

본 발명의 권리는 다음에서 설명되는 실시예에 한정되지 않고 청구범위에 기재된 바에 의헤 정의되며, 본 발명의 분야에서 통상의 지식을 가진 자가 청구범위에 기제된 권리범위 내에서 다향한 변형과 개작을 할 수 있다는 것은 자명하다.The right of the present invention is not limited to the examples described below, but is defined by the claims It is self-evident that it can be done.

1 은 또는 구리를 한정 함유하게 되는 여성 생식기내 질병 예방 및 개선제 조성물의 제조1 Preparation of a composition for preventing and ameliorating diseases in the female reproductive tract that contains silver or copper limitedly

재료의 준비.preparation of materials.

은 또는 구리의 수용액화 공정은 종래의 전기분해 방법 또는 나노화 공정 또는 탄산칼슘 또는 SiO3를 용매로 하여 제조된 은 또는 구리용액 중 탄산칼슘을 용매로 하여 제조된 은 또는 구리의 이온수를 사용한다.The silver or copper aqueous solution process uses ionized water of silver or copper prepared by using calcium carbonate as a solvent in a solution of silver or copper prepared using a conventional electrolysis method or nanoization process or calcium carbonate or SiO 3 as a solvent.

그러나 본원에서는 탄산칼슘을 용매로 하여 제조된 순도 99.99%의 은 또는 구리가 각각 0.0005%씩 함유된 각각의 용액을 각각 100ml 를 준비하고, 자작나무로부터 일출시켜 얻어진 수액 2000ml 를 준비하였다. 또한 점도제로 증점제 중 하이셀 150g 과 풀빅산이 0.001%가 포함된 광천수를 강원도 영월에서 60ml 를 채취하여 준비하였다. 또한 강원도 정선에서 0.0005%가 포함된 개르마늄 광청수를 90ml 를 준비하였다.However, in the present application, 100 ml of each solution containing 0.0005% of silver or copper of 99.99% purity prepared using calcium carbonate as a solvent was prepared, respectively, and 2000 ml of a sap obtained by sunrise from a birch tree was prepared. In addition, as a viscosity agent, 150 g of Hisel and 0.001% of fulvic acid were prepared by collecting 60 ml of mineral water from Yeongwol, Gangwon-do. Also, 90ml of germanium mineral water containing 0.0005% was prepared in Jeongseon, Gangwon-do.

또한 1% 히알루론산 20ml 와 0.001% EGF 4ml, ECM 콜라겐과 엘라스틴 2g 을 각각 준비하였다.In addition, 20 ml of 1% hyaluronic acid, 4 ml of 0.001% EGF, and 2 g of ECM collagen and elastin were prepared, respectively.

제조Produce

2000cc 가열 용기 2 개에 각각 은 또는 구리 용액과 자작나무 수액과 풀비산수와 게르마늄수를 투입하여 상기 각 금속별로 각각 1120ml 의 은 또는 구리이온이 포함된 용액을 제조하고, 상기 용액을 가열하여 섭씨 50-60 도 온도에서 하이셀를 첨가시켜 혼합 호모믹서기로 섭씨 50 도 이하가 될 때까지 교반하고, 젤형태의 물질를 제조한 후 여기에 각각 히알루론산 과 ECM, 엘라스틴, EGF 를 첨가시키고 교반시키고, 냉각시켜 점도가 있는 젤형태의 은 또는 구리가 함유된 조성물를 제조하여 주사형 주입용기에 각 2ml 씩 각각 충진시켜, 은 함유 조성물 510 개, 구리함유 510 개의 여성 생식기 질병 예방 및 개선제를 제조하였다.Silver or copper solution, birch sap, grass arsenic water, and germanium water were put into two 2000 cc heating containers, respectively, to prepare a solution containing 1120 ml of silver or copper ions for each metal, and the solution was heated to 50 degrees Celsius After adding Hycell at a temperature of -60 degrees Celsius and stirring until it is below 50 degrees Celsius with a mixing homomixer, a gel-like material is prepared, and hyaluronic acid, ECM, elastin, and EGF are added thereto, respectively, stirred, and cooled. A composition containing silver or copper in the form of a viscous gel was prepared and 2 ml each was filled in an injection container, respectively, to prepare 510 silver-containing compositions and 510 copper-containing compositions for preventing and improving female genital diseases.

2. 천연 식물성 추출물에 은 또는 구리 이온을 함유하는 여성 생식기내 질병 예방 및 개선제 조성물의 의 제조2. Preparation of a composition for preventing and ameliorating diseases in female reproductive organs containing silver or copper ions in a natural vegetable extract

재료의 준비preparation of materials

탄산칼슘을 용매로 제조된 순도 99.99%의 은 또는 구리가 각각 0.001g 이 함유된 금 또는 은용액 200ml 를 각각 준비하고 점도제들 중 선택한 하이셀 100g 과 풀빅산이 0.001%가 포함된 광천수를 강원도 영월에서 20ml 를 재취하여 준비하였다.Prepare 200ml of gold or silver solution each containing 0.001g of silver or copper of 99.99% purity prepared with calcium carbonate as a solvent, 100g of Hisel selected from among the viscosity agents, and mineral water containing 0.001% of fulvic acid in Yeongwol, Gangwon-do It was prepared by re-collecting 20 ml from

또한 건조된 사상자, 오미자, 목과, 후박, 상백피, 고삼, 황기, 병풀 각각 6g 씩 준비하고, 자작나무수액 2000ml와 하이셀 100g, 1% 히알루론산 3ml와 0.0001% EGF 2ml, 0.0001% 풀빅산 광천수 40ml. 를 준비하였다.Also, prepare 6 g each of dried sorghum, Schisandra, mulberry, zucchini, sagebrush, ginseng, astragalus, and centella, 2000 ml of birch sap, 100 g of Hycell, 3 ml of 1% hyaluronic acid, 2 ml of 0.0001% EGF, 40 ml of 0.0001% fulvic acid mineral water. . was prepared.

제조공정Manufacture process

1. 준비한 8종류의 식물성 혼합 물질 48g 을 70%알코올 1000ml 에 7 일 동안 함침시켜 유효물질를 추출하고 상기 추출물이 포함된 알콜를 진공 농축기에 넣어 알콜과 물를 증발시켜 식물성 혼합 추출용액 200ml 를 제조한다.1. Extract the active substance by impregnating 48 g of the prepared 8 kinds of vegetable mixture in 1000 ml of 70% alcohol for 7 days. Put the alcohol containing the extract in a vacuum concentrator and evaporate the alcohol and water to prepare 200 ml of a vegetable mixture extraction solution.

상기 자작나무 수액에 상기 공정에서 수득한 은용액 또는 구리용액 그리고 풀빅산과 식물성 종합 추출물을 혼합시켜 잘 교반시킨 후, 섭씨 50 도-60 도 온도에서 증점제로서 하이셀를 포함시켜 잘 교반시키고 섭씨 50 도 이하의 온도에서 히하루론산과 ECM, EGF 를 투입하고 충분하게 교반시켜 점도가 있는 젤형태의 은이온 또는 구리이온과 식물성 유효물질이 함유된 여성 성기 질병의 예방 및 개선제를 제조하였다.After mixing the birch sap with the silver solution or copper solution obtained in the above process, and fulvic acid and the comprehensive plant extract, well stirred, the mixture was stirred well by including Hycell as a thickener at a temperature of 50 to 60 degrees Celsius and stirred well below 50 degrees Celsius Hyharuronic acid, ECM, and EGF were added at a temperature of , and stirred sufficiently to prepare a preventive and ameliorating agent for female genital diseases containing silver ions or copper ions in the form of viscous gels and vegetable active substances.

상기 잴형태의 조성물를 주사기 형태의 용기에 2ml 용량을 각각 충진시켜 식물성 추출물에 은이온이 함유된 여성 생식기 질병 예방 및 개선제 510 개와 식물성 추출물에 구리이온이 함유된 여성 생식기 예방 및 개선제 조성물 510개를 제조하였다.By filling a syringe-type container with 2 ml of the above-mentioned measurable composition, 510 female genital disease prevention and improvement agents containing silver ions in vegetable extracts and 510 female genital prevention and improving agent compositions containing copper ions in vegetable extracts were prepared did

효과 실함loss of effect

임상에 의한 사용 효과 확인Confirmation of use effect by clinical

40 대 여성 50 명. 60 대여성 70 명. 70 대여성 20 명에게 각각 3 개씩 공급하여 일주일에 1 개씩 사용하게 한 후 그 결과를 확인 하였다. 생식기에 관한 것으로 상세한 사용 후 기는 없지만 사용자 전원이 대단히 만족한다는 의사를 표하였다.50 women in their 40s. 60 rental 70 people. 70 For 20 people, 3 each were supplied, and the results were confirmed after having them use 1 each a week. Although there are no detailed reviews regarding the genital organs, all users expressed their intention to be very satisfied.

Claims (8)

여성 생식기 질병의 예방 및 개선 유효성분으로 은 또는 구리 중 어느 한 성분이 일종 이상의 기능성 식물의 추출물에 함유되어 조성된 조성물인 것을 특징으로 하는 여성의 생식기 질병 예방 및 개선제 조성물.Prevention and improvement of female genital diseases A composition for preventing and improving female genital diseases, characterized in that the composition is composed of one or more components of silver or copper as an active ingredient contained in an extract of one or more functional plants. 청구항 1의 은 또는 구리는, 용액(콜로이드), 이온수, 나노입자 형태들 중 어느 하나의 형태로 함유된 것.The silver or copper of claim 1 is contained in any one of the form of a solution (colloid), ionized water, and nanoparticles. 청구항 1의 기능성 식물의 추출물은 사상자, 오미자. 황기. 목과. 감초. 인동. 신이. 하고초. 토봉령. 만형자. 고삼. 지실. 우방자. 목단피. 두충. 선인장(백년초, 천년초)알로에, 호황련. 후박. 구기자. 쇄양. 산약. 인삼, 삼백초의 무리 중 선택한 일종 이상의 식물로부터 추출한 추출물인 것.The functional plant extract of claim 1 is Sasangsaeng, Schisandra Schisandra. Astragalus. neck and. licorice. Indong. God. hagocho. Tobongyeong. man-made. high sam. Loss. ally. wood skin. headworm. Cactus (Baeknyeoncho, Cheonnyeoncho)Aloe, fenugreek. humpback. goji berry. shunyang. acid medicine. It is an extract extracted from one or more plants selected from the group of ginseng and ginseng. 청구항 1, 청구항 2에 있어 여성 생식기 질병 예방 및 개선제에 포함되는 은 또는 구리의 함유량은 조성물 총 중량에 은, 구리중 어느 하나가 0.0005%( 5ppm) 이상 함유된 것.The method according to claim 1 or claim 2, wherein the content of silver or copper included in the agent for preventing and improving female genital diseases is 0.0005% (5 ppm) or more of either silver or copper in the total weight of the composition. 청구항 1의 여성 생식기 질병 예방 및 개선제 조성물은 유기 풀빅과 유기 게르마늄 중 어느 일종 이상이 조성물 총 중량에 각각 0.0005%(1ppm)이상 함유되어 조성된 조성물인 것.The composition for preventing and improving female genital disease of claim 1 is a composition comprising at least 0.0005% (1ppm) of organic fulvic and organic germanium, each of which is at least 0.0005% (1ppm) in the total weight of the composition. 청구항 1. 청구항 3-청구항 - 청구항 8에 있어 여성 생식기 질병 예방 및 개선제 조성물은 액체형태, 젤형태, 크림 형태, 고체 형태 중 어느 한 형태로 제조된 조성물 인 것.1. The composition for preventing and ameliorating female genital disease according to claim 3 - 8, wherein the composition is prepared in any one of a liquid form, a gel form, a cream form, and a solid form. 청구항 1. 청구항 3-청구항 6, 청구항 8에 있어 조성물은 여성 질에 발생되는 질병의 예방, 개선, 또는 치료와 병행하여 윤활제 용도로 사용되는 것을 특징으로 하는 여성 생식기 질병의 예방 및 개선제 조성물1. The composition according to claim 3, 6 or 8, wherein the composition is used as a lubricant in parallel with the prevention, improvement, or treatment of diseases occurring in the female vagina. 청구항 1, 청구항 3-청구항 7에 있어 조성물은 용매로 나무의 수액이 포함되는 것을 특징으로하는 여성 생식기 질병의 예방 및 개선제 조성물The composition for preventing and ameliorating female genital diseases according to claim 1, 3 - 7, wherein the composition contains tree sap as a solvent.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102486025B1 (en) * 2022-09-19 2023-01-09 지비비 주식회사 Composition for feminine cleanser comprising live lactic acid bacteria and helpful for improving vaginitis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100646593B1 (en) 2005-07-01 2006-11-23 김의섭 Composition comprising the extract of phellinus mushroom and lactic acid for protecting and treating vaginal viral diseases and uterine cancer
KR101235370B1 (en) 2010-08-30 2013-02-20 강동원 Vaginal cleanser composition for alleviating symptoms of a vaginitis and a kit for vaginal cleansing comprising the same
KR101920749B1 (en) 2016-08-31 2018-11-21 주식회사 돌도2소프트 Vagina Washing Composition for Female, and Moistened Tissues Containing Vagina Washing Composition for Female

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100646593B1 (en) 2005-07-01 2006-11-23 김의섭 Composition comprising the extract of phellinus mushroom and lactic acid for protecting and treating vaginal viral diseases and uterine cancer
KR101235370B1 (en) 2010-08-30 2013-02-20 강동원 Vaginal cleanser composition for alleviating symptoms of a vaginitis and a kit for vaginal cleansing comprising the same
KR101920749B1 (en) 2016-08-31 2018-11-21 주식회사 돌도2소프트 Vagina Washing Composition for Female, and Moistened Tissues Containing Vagina Washing Composition for Female

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102486025B1 (en) * 2022-09-19 2023-01-09 지비비 주식회사 Composition for feminine cleanser comprising live lactic acid bacteria and helpful for improving vaginitis

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