CN108498731A - Gynaecologic vaginal external used medicine and preparation method thereof - Google Patents

Gynaecologic vaginal external used medicine and preparation method thereof Download PDF

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Publication number
CN108498731A
CN108498731A CN201810552869.5A CN201810552869A CN108498731A CN 108498731 A CN108498731 A CN 108498731A CN 201810552869 A CN201810552869 A CN 201810552869A CN 108498731 A CN108498731 A CN 108498731A
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grams
external used
gynaecologic vaginal
used medicine
vaginal external
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叶松宽
谢杰
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Hangzhou Loose Biological Technology Co Ltd
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Hangzhou Loose Biological Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/738—Rosa (rose)
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    • A61K36/74—Rubiaceae (Madder family)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/79—Schisandraceae (Schisandra family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

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Abstract

The present invention discloses gynaecologic vaginal external used medicine and preparation method thereof, containing ginseng, safflower, Radix Angelicae Sinensis, kuh-seng, Herba Cymbopogonis Citrari, Asian puccoon, lily, frutus cnidii, Radix Paeoniae Alba, mulberries, Morinda officinalis, Cortex Eucommiae, Schisandra chinensis, stamen nelumbini, motherwort, holy basil, honey, Rosa Damascana.This medical instrument, which has, restores vagina elasticity, reappears vagina and compacts, remove internal germ, eliminate privates peculiar smell, anti-aging and other effects has good application on gynecological clinic.

Description

Gynaecologic vaginal external used medicine and preparation method thereof
Technical field
The present invention relates to Amino-Cerv technical fields, and in particular to a kind of gynaecologic vaginal external used medicine and preparation method thereof, The gynaecologic vaginal external used medicine is that pure plant essence, Small side effects and woman are good with effect.
Background technology
Gynaecological problem, for example seem female vagina, cervical erosion, fibroid etc., dramatically annoying women Daily life, directly affect physical and mental health and the love life of women, in numerous gynecological diseases, vaginal problems are not allow to neglect Depending on.
There are many muscle and ligaments for the vagina surrounding of normal female, so that it is kept certain tension, in vaginal walls mucous membrane It is upper to increase frictional force in sexual life there are many more pleat, and after property history is longer or vaginal delivery, vagina mucosa, flesh Rou Deng soft tissue relaxations even result in wound healing difference etc. after vaginal laceration, oldness laceration of perineum, perineum side cutting, that is, are commonly called as Vaginal relaxation, at present very to vaginal relaxation can only use modus operandi and drug method, modus operandi be easy to cause series complication, And it is bigger to human injury.And drug method is divided into as western modern medicine and traditional Chinese medicine, western modern medicine is chemical drug product, in use Side effect is larger, and irritation is larger.And traditional Chinese medicine is based on lotion, using process need by Chinese medicine dilution agent backlash wash vulva and Vagina, inconvenient for use, use is single.
In addition, the not clean menses etc. of garbage toxins, rheuminess object, dead skin cells in vagina pleat gap, row are to draw The reason of sending out gynecological disease various, to which the life to women brings inconvenience.
Invention content
The purpose of the present invention is to provide gynaecologic vaginal external used medicine and preparation method thereof, the gynaecologic vaginal externally applied drug Object, which is pure plant essence, securely and reliably can penetrate deep into vaginal cell layer, activation vaginal cell activity, repair vagina by Tissue is damaged, vagina elasticity is restored, vagina is reappeared and compacts, improves privates caused by a variety of causes and relaxes, improve the quality of sexual life.
The purpose of the present invention is to provide gynaecologic vaginal external used medicine and preparation method thereof, the gynaecologic vaginal externally applied drug Object removes internal germ, eliminates privates peculiar smell, effectively reduces the occurrence probability of gynecological disease, improves involutional various diseases Shape.
The purpose of the present invention is to provide gynaecologic vaginal external used medicine and preparation method thereof, the gynaecologic vaginal externally applied drug Object shows anti-aging, beautifying face and moistering lotion, improves privates relaxation, improve labia color, increase lubricity, increase in use Pleasant sensation adjusts privates acid-base balance, the advantage of bacteriostasis antibiosis.
In order to realize the above goal of the invention, the present invention provides a gynaecologic vaginal external used medicine, by the raw material of following weight ratio Composition：9-12 grams of ginseng, 3-6 grams of safflower, 3-6 grams of Radix Angelicae Sinensis, 6-9 grams of kuh-seng, 8-12 grams of Herba Cymbopogonis Citrari, 6-9 grams of Asian puccoon, lily 6-12 Gram, 6-12 grams of frutus cnidii, 9-15 grams of Radix Paeoniae Alba, mulberries are 9-15 grams sub-, 9-15 grams of Morinda officinalis, 9-15 grams of Cortex Eucommiae, 7-12 grams of Schisandra chinensis, 6-9 grams of stamen nelumbini, 12-15 grams of motherwort, 6-9 grams of holy basil, 2-4 parts of honey, Rosa Damascana 3-5 drops.
According to another aspect of the present invention, a kind of preparation method of gynaecologic vaginal external used medicine is provided, which is characterized in that packet Include following steps：
S1:First chamber in formula is mixed according to the ratio and is smashed, steamer steaming is then placed in, wherein first combination Object includes ginseng, safflower, Asian puccoon, paenoiae alba, Cortex Eucommiae, Schisandra chinensis, stamen nelumbini, Radix Angelicae Sinensis, mulberries；
S2：Red yeast rice is added in the medicinal material cooked in step sl to ferment as catalyst, is dried after fermentation spare；
S3：The medicinal material dried in step S2 is crossed with ethyl alcohol lid after being soaked for a period of time, filters off the dregs of a decoction and obtain filtrate；With And
S4：Second chamber in formula is mixed according to the ratio and is smashed, with 5 times of amounts in the ethyl alcohol lid of the second chamber Cross after being soaked for a period of time and filter off the dregs of a decoction and obtain filtrate, the second chamber include kuh-seng, lemon-grass, lily, frutus cnidii, Morinda officinalis, motherwort, holy basil；
S5：The filtrate that the step S3 and the step S4 are obtained, evaporated under reduced pressure obtain gynaecologic vaginal external used medicine.
In some embodiments, first chamber is broken to 15-30 mesh sizes, the step S4 in the step S1 The second chamber described in is broken to 15-30 mesh sizes.
In some embodiments, first chamber is broken to 20 mesh sizes in the step S1, and the step S4 works as Described in second chamber it is broken to 20 mesh sizes.
In some embodiments, the ethyl alcohol in the step S3 and step S4, including the concentration do not fermented The concentration of ethyl alcohol and fermentation more than or equal to 95% is more than or equal to 75% ethyl alcohol, described to impregnate to cover immersion, the step It is 4-8 hour to be impregnated in S3, impregnates 36-72 hour in the step S4.
In some embodiments, evaporated under reduced pressure condition is negative pressure 0.08pa, temperature 55-60 degree.
In some embodiments, weight prepares the gynaecologic vaginal external application 5%-10%, oil of juniper wood 50-65% and Jojoba Oily 25-40% forms essential oil.
In some embodiments, Acritamer 940, trehalose, glycerine, polyethylene glycol 400 are added in composite formula, it is described Gynaecologic vaginal external used medicine is gel preparations or ointment.
Specific implementation mode
It is understood that term " one " is interpreted as " at least one " or " one or more ", i.e., in one embodiment, The quantity of one element can be one, and in a further embodiment, the quantity of the element can be multiple, and term " one " is no It can be interpreted as the limitation to quantity.
The present invention provides a gynaecologic vaginal external used medicine, it is characterised in that：It is made of the raw material of following weight ratio：Ginseng 9- 12 grams, 3-6 grams of safflower, 3-6 grams of Radix Angelicae Sinensis, 6-9 grams of kuh-seng, 8-12 grams of Herba Cymbopogonis Citrari, 6-9 grams of Asian puccoon, 6-12 grams of lily, frutus cnidii 6- 12 grams, 9-15 grams of Radix Paeoniae Alba, mulberries are 9-15 grams sub-, 9-15 grams of Morinda officinalis, 9-15 grams of Cortex Eucommiae, 7-12 grams of Schisandra chinensis, 6-9 grams of stamen nelumbini, 12-15 grams of motherwort, 6-9 grams of holy basil, 2-4 parts of honey, Rosa Damascana 3-5 drops.
Further, it is made of the raw material of following weight ratio：10 grams of ginseng, 4 grams of safflower, 4 grams of Radix Angelicae Sinensis, 7 grams of kuh-seng, fragrant lance 10 grams of grass, 8 grams of Asian puccoon, 10 grams of lily, 10 grams of frutus cnidii, 12 grams of Radix Paeoniae Alba, 13 grams of mulberries, 13 grams of Morinda officinalis, 13 grams of Cortex Eucommiae, five 10 grams of taste, 8 grams of stamen nelumbini, 13 grams of motherwort, 8 grams of holy basil, 3 parts of honey, Rosa Damascana 4 drip.
Further, it is made of the raw material of following weight ratio：11 grams of ginseng, 5 grams of safflower, 5 grams of Radix Angelicae Sinensis, 8 grams of kuh-seng, fragrant lance 11 grams of grass, 7 grams of Asian puccoon, 11 grams of lily, 11 grams of frutus cnidii, 13 grams of Radix Paeoniae Alba, 14 grams of mulberries, 12 grams of Morinda officinalis, 12 grams of Cortex Eucommiae, five 9 grams of taste, 7 grams of stamen nelumbini, 14 grams of motherwort, 7 grams of holy basil, 2 parts of honey, Rosa Damascana 3 drip.
Further, it is made of the raw material of following weight ratio：11 grams of ginseng, 4 grams of safflower, 4 grams of Radix Angelicae Sinensis, 7 grams of kuh-seng, fragrant lance 9 grams of grass, 8 grams of Asian puccoon, 7 grams of lily, 8 grams of frutus cnidii, 10 grams of Radix Paeoniae Alba, 10 grams of mulberries, 15 grams of Morinda officinalis, 11 grams of Cortex Eucommiae, the five tastes 11 grams of son, 8 grams of stamen nelumbini, 13 grams of motherwort, 8 grams of holy basil, 4 parts of honey, Rosa Damascana 5 drip.
Further, it is made of the raw material of following weight ratio：10 grams of ginseng, 5 grams of safflower, 6 grams of Radix Angelicae Sinensis, 6 grams of kuh-seng, fragrant lance 12 grams of grass, 6 grams of Asian puccoon, 8 grams of lily, 7 grams of frutus cnidii, 11 grams of Radix Paeoniae Alba, 12 grams of mulberries, 10 grams of Morinda officinalis, 10 grams of Cortex Eucommiae, the five tastes 8 grams of son, 7 grams of stamen nelumbini, 12 grams of motherwort, 6 grams of holy basil, 2 parts of honey, Rosa Damascana 3 drip.
Pharmacology analysis：
Ginseng：Invigorating qi for relieving desertion, nourishes blood and promotes the production of body fluid.
Safflower：Promoting blood circulation, dysmenorrhoea, removing blood stasis and analgesics.
Radix Angelicae Sinensis：It enriches blood, invigorates blood circulation, menstruction regulating and pain relieving lubricates enteron aisle.
Kuh-seng：Heat-clearing and damp-drying drug, desinsection, diuresis.Treat malignant sore.
Asian puccoon：Detoxicatied spot-removing, clearing heat for detumescence promote cell growth.
Lily：Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, beautifying face and moistering lotion.
Frutus cnidii：Strong sun kidney-nourishing dispels pathogenic wind and remove dampness, treats cold uterus, is infertile, leukorrhea with reddish discharge.
Morinda officinalis：Treat uterus cold infertile, irregular menstruation, few abdomen crymodynia, arthralgia pain due to rheumatism.
Cortex Eucommiae：Main pain along spinal column, bowl spares strengthening the essence gas, hard muscles and bones, Qiang Zhi are wet except itching under the moon
Schisandra chinensis：Restrain astringent method, nourishing generate fluid, kidney calming.
Motherwort：Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema.
Holy basil：Cold-dispelling is warded off foul.
Honey：It brightens, goes to wrinkle.
Stamen nelumbini：Adstringency has receipts the moon, determines the wonderful of soul.
Herba Cymbopogonis Citrari：Naturally contain citrus scented, there is the effect of promoting the sexual maturity with stomach ventilation, restoring consciouness.
Mulberries：Nourishing yin and nourishing blood；It promotes the production of body fluid；Ease constipation.
Radix Paeoniae Alba：Cloudy receipts sweat is held back in nourishing blood and liver, analgesic in delaying.
Rosa Damascana：It is referred to as " after essential oil ".Female incretion can be adjusted, uterus is nourished, alleviates dysmenorrhoea, improvement property is cold The light and climacteric more phase is uncomfortable.
This medical instrument has following primary efficacy：
1, vagina vigor is repaired：
Vaginal cell layer is penetrated deep into, activation vaginal cell activity, i.e., microcirculatory vascular is adjusted, Lymphatic Circulation excludes poison Element increases local vascular supply, oxygen supply and nutrition supply, repairs vagina damaged tissues, restores vagina elasticity, reappears vagina It compacts, postpones climacteric, improve privates caused by a variety of causes and relax, increase lubricity and pleasant sensation, improve the quality of sexual life, Achieve the effect that increase orgasm and reaches koro.
2, aging is resisted：
Lymphatic return is activated, the epithelium that quickly peeling and exclusion are piled up in the rubbish in uterus and vagina for a long time and necrosis falls off Cell, the source of infection for eliminating bacterium and germ, it is elastic and smooth, disappear to make intravaginal and the big nymphae of external cause restore ruddy It moves back melanin pigmentation and female face is gloomy, chloasma, adjust endocrine, anti-aging beauty-care beauty treatment improves involutional various Symptom.
3, anti-inflammatory is antibacterial：
The various bacteriums and germ grown in vagina and uterus are persistently killed, clear internal germ eliminates privates peculiar smell, Vagina acid-base property is balanced, the acid-base balance in privates is adjusted, harmful bacteria group is inhibited to grow again, eliminates peculiar smell, improves privates Color, can effective preventative disease.
4, mitigate women pain：
The pregnant woman of natural labor uses in advance, can mitigate the pain of production process, shortening labor, and the women in postpartum can be made fast Speed repairs privates wound and restores antenatal state, is the woman of the salubrious water of deflation the more.
In addition, the preparation method that the present invention provides a gynaecologic vaginal external used medicine is as follows：
S1：First chamber in formula is mixed according to the ratio and is smashed to 15-30 mesh sizes, steamer steaming is then placed in；
S2：1/4 to 1/3 red yeast rice conduct of the weight of the medicinal material cooked described in addition in the medicinal material cooked in step sl Catalyst ferments, and fermentation temperature is added, dries after fermentation spare in 36-39 degree, the red yeast rice；
S3:The concentration of ethyl alcohol or fermentation by the medicinal material dried in step S2 with the concentration that do not ferment more than or equal to 95% Ethyl alcohol more than or equal to 75% covered immersion, and 4-8 hours, filtered off the dregs of a decoction after being soaked for a period of time and obtain filtrate；
S4:Second chamber in formula is mixed according to the ratio and is smashed to 15-30 mesh sizes, with 5 times measure fermentation it is dense Ethyl alcohol of the degree more than or equal to 95% or the concentration of fermentation are more than or equal to 75% ethyl alcohol, cover immersion 4-8 hours, and impregnate 36-72 A dregs of a decoction that as a child filtered off afterwards obtain filtrate；And
S5:The filtrate that mixing step S3 and step S4 are obtained merges, and is steamed in negative pressure 0.08pa, the decompression of temperature 55-60 degree Do paste.
Ginseng, safflower, Asian puccoon, paenoiae alba, Cortex Eucommiae, Schisandra chinensis, stamen nelumbini, Radix Angelicae Sinensis, mulberries described in the step S2 are returned For first kind composition.The step S4 kuh-seng, lemon-grass, lily, frutus cnidii, Morinda officinalis, motherwort, holy basil described in It is classified as the second class composition.
Also, in a preferred embodiment, the first chamber and the second chamber are broken to 20 mesh sizes.
In some embodiments, prepare by weight percentage the plant extracts 5%-10%, oil of juniper wood 50-65% and The dosage form of SIMMONDSIA CHINENSIS SEED OIL 25-40% composition essential oils.
In some embodiments, cataplasm can be added in the composite formula and can be used as gel preparations, the cataplasm Can be one kind or combinations thereof in carbomer, acrylic acid or first acrylic acid three, the cataplasm content in gel preparations and tool The preparation method of body gel is the prior art.
In some embodiments, Acritamer 940, trehalose, glycerine, polyethylene glycol 400 are added in the composite formula Plaster dosage form is done, preparation method is the prior art.
The gynaecologic vaginal external used medicine of the present invention is applied to vagina position and the intravaginal of women, kidney outside when in use Yu cave is to Changqiang acupoint (namely waist and buttocks) and the additional groin of lower abdomen.
When this formula is applied to test with female rat by we：
The mother mouse that uterus falls off after largely having given birth to mouselet is selected, and it is used continuously outside two days gynaecologic vaginals With drug, the results showed that obviously restore in the uterus of mother mouse.
Similarly, which is also applied to the animal of other Uterine Prolapses by we, as a result its uterus recovery situation Also with obvious effects.
The gynaecologic vaginal external used medicine has also obtained good application in clinical test, and vagina-shrinking expellent effect is aobvious It writes, specific model case is as follows：
1, Wu, female, 32 years old, intrauterine pregnancy,delivered had 2 children, the gynaecologic vaginal external used medicine of continuous application the present embodiment one Month, vaginal wall regenerates by atrophy aging before, becomes extremely to compact.
2, Liu, female, 26 years old, property history 4 years, Colpitis mycotica, pruritus vulvue, vaginal fluid was more, on the inside of nymphae and Vagina mucosa is red and swollen, and the gynaecologic vaginal external used medicine of continuous application the present embodiment one week, itch is substantially reduced, rehabilitation at erosion.
3, Zhang, female, 52 years old, husband's sexual life was more active, and the Ms Zhang that can have sexual intercourse every time is afraid of very much, main vagina It is excessively dry, it tries out and once realizes that oneself becomes 25 feeling, 2 months descendants also young teens is used continuously.
The present invention is not limited to above-mentioned preferred forms, anyone can show that other are various under the inspiration of the present invention The product of form, however, make any variation in its shape or structure, it is every that there is skill identical or similar to the present application Art scheme, is within the scope of the present invention.

Claims (10)

1. a gynaecologic vaginal external used medicine, which is characterized in that be made of the raw material of following weight ratio：9-12 grams of ginseng, safflower 3-6 Gram, 3-6 grams of Radix Angelicae Sinensis, 6-9 grams of kuh-seng, 8-12 grams of Herba Cymbopogonis Citrari, 6-9 grams of Asian puccoon, 6-12 grams of lily, 6-12 grams of frutus cnidii, Radix Paeoniae Alba 9- 15 grams, mulberries are 9-15 grams sub-, 9-15 grams of Morinda officinalis, 9-15 grams of Cortex Eucommiae, 7-12 grams of Schisandra chinensis, 6-9 grams of stamen nelumbini, motherwort 12-15 Gram, 6-9 grams of holy basil, 2-4 parts of honey, Rosa Damascana 3-5 drops.
2. gynaecologic vaginal external used medicine according to claim 1, which is characterized in that be made of the raw material of following weight ratio： 10 grams of ginseng, 4 grams of safflower, 4 grams of Radix Angelicae Sinensis, 7 grams of kuh-seng, 10 grams of Herba Cymbopogonis Citrari, 8 grams of Asian puccoon, 10 grams of lily, 10 grams of frutus cnidii, Radix Paeoniae Alba 12 grams, mulberries 13 grams, 13 grams of Morinda officinalis, 13 grams of Cortex Eucommiae, 10 grams of Schisandra chinensis, 8 grams of stamen nelumbini, 13 grams of motherwort, 8 grams of holy basil, 3 parts of honey, Rosa Damascana 4 drip.
3. gynaecologic vaginal external used medicine according to claim 1, which is characterized in that be made of the raw material of following weight ratio： 11 grams of ginseng, 5 grams of safflower, 5 grams of Radix Angelicae Sinensis, 8 grams of kuh-seng, 11 grams of Herba Cymbopogonis Citrari, 7 grams of Asian puccoon, 11 grams of lily, 11 grams of frutus cnidii, Radix Paeoniae Alba 13 grams, mulberries 14 grams, 12 grams of Morinda officinalis, 12 grams of Cortex Eucommiae, 9 grams of Schisandra chinensis, 7 grams of stamen nelumbini, 14 grams of motherwort, 7 grams of holy basil, bee 2 parts of honey, Rosa Damascana 3 drip.
4. gynaecologic vaginal external used medicine according to claim 1, which is characterized in that be made of the raw material of following weight ratio： 10 grams of ginseng, 5 grams of safflower, 6 grams of Radix Angelicae Sinensis, 6 grams of kuh-seng, 12 grams of Herba Cymbopogonis Citrari, 6 grams of Asian puccoon, 8 grams of lily, 7 grams of frutus cnidii, Radix Paeoniae Alba 11 Gram, mulberries 12 grams, 10 grams of Morinda officinalis, 10 grams of Cortex Eucommiae, 8 grams of Schisandra chinensis, 7 grams of stamen nelumbini, 12 grams of motherwort, 6 grams of holy basil, honey 2 parts, the drop of Rosa Damascana 3.
5. a kind of preparation method preparing any gynaecologic vaginal external used medicine of claim 1 to 4, which is characterized in that packet Include following steps：
S1:First chamber in formula is mixed according to the ratio and is smashed, steamer steaming is then placed in, wherein the first chamber packet Include ginseng, safflower, Asian puccoon, paenoiae alba, Cortex Eucommiae, Schisandra chinensis, stamen nelumbini, Radix Angelicae Sinensis, mulberries；
S2：Red yeast rice is added in the medicinal material cooked in step sl to ferment as catalyst, is dried after fermentation spare；
S3：The medicinal material dried in step S2 is crossed with ethyl alcohol lid after being soaked for a period of time, filters off the dregs of a decoction and obtain filtrate；And
S4：Second chamber in formula is mixed according to the ratio and is smashed, leaching is crossed in the ethyl alcohol lid of the second chamber with 5 times of amounts The dregs of a decoction are filtered off after bubble a period of time and obtain filtrate, and the second chamber includes kuh-seng, lemon-grass, lily, frutus cnidii, Morinda offcinalis How It, motherwort, holy basil；
S5：The filtrate that the step S3 and the step S4 are obtained, evaporated under reduced pressure obtain gynaecologic vaginal external used medicine.
6. the preparation method of gynaecologic vaginal external used medicine according to claim 5, which is characterized in that in the step S1 First chamber is broken to 15-30 mesh sizes, and step S4 second chambers described in are broken big to 15-30 mesh It is small.
7. the preparation method of gynaecologic vaginal external used medicine according to claim 6, which is characterized in that the step S3 and Ethyl alcohol in the step S4, including the ethyl alcohol of the concentration do not fermented more than or equal to 95% and the concentration of fermentation are more than or equal to 75% ethyl alcohol, it is described to impregnate to cover immersion, it impregnates 4-8 hour in the step S3, is impregnated in the step S4 36-72 hour.
8. according to the preparation method of any gynaecologic vaginal external used medicines of claim 5-7, which is characterized in that decompression is steamed Dry condition is negative pressure 0.08pa, temperature 55-60 degree.
9. according to the preparation method of any gynaecologic vaginal external used medicines of claim 5-7, which is characterized in that weight is prepared The gynaecologic vaginal external application 5%-10%, oil of juniper wood 50-65% and SIMMONDSIA CHINENSIS SEED OIL 25-40% form essential oil.
10. according to the preparation method of any gynaecologic vaginal external used medicines of claim 5-7, which is characterized in that composition In formula be added Acritamer 940, trehalose, glycerine, polyethylene glycol 400, the gynaecologic vaginal external used medicine be gel preparations or Ointment.
CN201810552869.5A 2018-05-31 2018-05-31 Gynaecologic vaginal external used medicine and preparation method thereof Withdrawn CN108498731A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112755141A (en) * 2021-01-22 2021-05-07 广东省毅康生物科技有限公司 A preparation for treating gynecological diseases and its preparation method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465358A (en) * 2002-06-21 2004-01-07 陈必诚 Vagina girdle, clean and anti-inflamation agent for female
KR20110069967A (en) * 2009-12-18 2011-06-24 이해민 Nature a pill composition for prevention depilation and improvement of hair growth comprising traditional oriental extraction and manufacturing method thereof
CN105663788A (en) * 2016-02-29 2016-06-15 戴云 Medicinal composition, ointment and medicament capable of contracting female vagina

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465358A (en) * 2002-06-21 2004-01-07 陈必诚 Vagina girdle, clean and anti-inflamation agent for female
KR20110069967A (en) * 2009-12-18 2011-06-24 이해민 Nature a pill composition for prevention depilation and improvement of hair growth comprising traditional oriental extraction and manufacturing method thereof
CN105663788A (en) * 2016-02-29 2016-06-15 戴云 Medicinal composition, ointment and medicament capable of contracting female vagina

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112755141A (en) * 2021-01-22 2021-05-07 广东省毅康生物科技有限公司 A preparation for treating gynecological diseases and its preparation method

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