CN101897865A - Medicinal composition with function of removing acne and preparation method thereof - Google Patents
Medicinal composition with function of removing acne and preparation method thereof Download PDFInfo
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- CN101897865A CN101897865A CN2009100862214A CN200910086221A CN101897865A CN 101897865 A CN101897865 A CN 101897865A CN 2009100862214 A CN2009100862214 A CN 2009100862214A CN 200910086221 A CN200910086221 A CN 200910086221A CN 101897865 A CN101897865 A CN 101897865A
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- acne
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- poria
- flos rosae
- salviae miltiorrhizae
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Abstract
The invention discloses a medicinal composition with function of removing acne and a preparation method thereof. The medicinal composition is prepared from baical skullcap root, danshen root, weeping forsythiae, indian buead, aloe and rose according to a certain weight proportion. The medicinal composition is prepared into paste. The medicinal composition has the effect of removing the acne.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and preparation method thereof, belong to medicine or field of health care food with acne-dispelling function.
Background technology
Comedo is " acne ", " face Blisters " or " acne " again, is because a kind of dermatosis that hair follicle and sebaceous gland are blocked, inflammation caused.During adolescence, intravital hormone meeting stimulating hair growth promotes more heavy wool fat of smegma, and therefore hair and sebaceous gland pile up many materials, make the attached work of oils and fats and antibacterial, cause the reaction of red swelling of the skin.The cause of disease of acne (comedo) is clear and definite, be to be infected by the anaerobic propionibacterium acnes to cause, but it is multifactorial disease.The traditional Chinese medical science is thought: face nose and thoracic dorsal subordinate lung, primary disease are often hindered due to the skin by wind and heat in the lung meridian; Or because of surfeit delicious food, greasy, maror, the taste intrinsic heat is given birth in damp and hot, fumigates in face to form; Or because of the body in youth, in the green, sun heat rises, and fights mutually with wind and cold, due to the strongly fragrant resistance skin.In addition, being coated with the obstruction of cosmetics stimulation causing follicular orifice outward is the major incentive of primary disease.But main cause still is an adolescence reaches maturity, and the androgen level raises in the body, and the epithelial cell that chafe and hair follicle come off is gathered into yellow-white material thromboembolism in hair follicle, promptly form acne, young as hair follicle, sebum is difficult to discharge and the little pimple of canescence that forms, is hoary hair's acne.The acne that are exposed to the follicular orifice outside are blackhead because of air, dust, atmospheric pollution become black.The follicular canal intracavity also exists a large amount of propionibacterium acness in addition, sebum can be resolved into unsaturated fatty acid, cause hair follicle and the not inflammation of equal extent takes place on every side, and suppuration, tuberosity, cyst or sebaceous cyst etc. appear, prolonged and repeated inflammation can stay the cicatrix that difficulty heals on the face, makes the skin injustice, coarse ugly, and sebaceous secretion is smooth and inflammation repeatedly, increases the weight of to stimulate sebaceous secretion again, thereby forms vicious cycle.The traditional Chinese medical science thinks, acne is because patient's eating and drinking without temperance, and surfeit is pungent rich, causes stomach and large intestine intenseness of heat, the pyretic toxicity inner product, on attack in lung, steam in face, the diseases caused by exogenous pathogenic factor poison is evil, causes the heat in blood stasis at last, pents up skin and forms.
Summary of the invention
The invention provides a kind of new pharmaceutical composition, said composition has the function of the acne of dispelling.
Another object of the present invention provides the preparation method of aforementioned pharmaceutical compositions.
The present invention is achieved by the following technical solutions:
The present invention is made by the following weight proportion raw material:
Radix Scutellariae 15-40 part, Radix Salviae Miltiorrhizae 10-30 part, Fructus Forsythiae 10-30 part, Poria 5-20 part, Aloe 5-20 part, Flos Rosae Rugosae 5-20 part.
The preferred weight portion proportioning of described pharmaceutical composition is:
Radix Scutellariae 25-30 part, Radix Salviae Miltiorrhizae 18-22 part, Fructus Forsythiae 18-22 part, Poria 10-15 part, Aloe 10-15 part, Flos Rosae Rugosae 10-15 part.
Preparation of drug combination method of the present invention is as follows:
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are decocted with water twice, filter, merge extractive liquid,, drying is pulverized, and sieves, and adds distilled water then, stirs into pasty state, is prepared into unguentum and gets final product.
Pharmaceutical composition preferred manufacturing procedure of the present invention is as follows:
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 6-8 times of water gaging decoct twice, be respectively 1.5 hours, 1 hour, filter merge extractive liquid,, vacuum drying gets dry extract, pulverizes, and crosses 800 mesh sieves, add distilled water then, stir into pasty state, be prepared into unguentum and get final product.
In pharmaceutical composition of the present invention, the mechanism of action of each medicine is as follows:
Radix Scutellariae: bitter in the mouth, cold in nature, return lung, gallbladder, spleen, large intestine, small intestine meridian.Have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect is used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement etc.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature, GUIXIN, Liver Channel.Have promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, the removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, the effect of nourishing blood to tranquillize the mind can be used for menoxenia, the amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris etc.Modern study shows that Radix Salviae Miltiorrhizae has reparation and the regeneration that promotes tissue, makes to free circulation of the blood.
Fructus Forsythiae: bitter in the mouth, cool in nature, GUIXIN, liver, gallbladder meridian.Have heat-clearing and toxic substances removing, the effect of mass dissipating and swelling eliminating, can be used for treating warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, disease such as urine stranguria with urinary obstruction etc.Modern study shows, Fructus Forsythiae has effects such as antiinflammatory, antibiotic, antiviral, antiendotoxin, and the treatment acne is had certain curative effect.
Poria: sweet in the mouth, light, property is flat, returns lung, stomach, kidney channel.Have promoting diuresis to eliminate damp pathogen, the effect of spleen invigorating mind calming can be used for the edema oliguria, the phlegm retention vertigo and palpitation, and insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, the palpitation with fear insomnia waits disease.
Aloe: bitter in the mouth, cold in nature, return liver, large intestine channel.Have and rush down down, liver heat removing, parasiticidal effect can be used for constipation with heat retention, liver-fire headache, conjunctival congestion infantile convulsion, abdominal pain due to worm stagnation, scabies, diseases such as hemorrhoid complicated by anal fistula.Studies show that, the effect that contained Aloe polysaccharide and vitamin have good nutrition, moisten, brighten the skin of human body in the Aloe, and offset except that acne good effect is arranged.
Flos Rosae Rugosae: sweet in the mouth, little hardship, warm in nature, return liver, spleen channel.Have promoting QI circulation for relieving depression, and blood, the analgesic effect can be used for stomachache due to hyperactive liver-QI attacking the stomach, the lack of appetite vomiting and nausea, and diseases such as pouncing on the pain of injury is fallen in menoxenia.Studies show that Flos Rosae Rugosae has endocrine regulation, the effect of beauty treatment.
The present invention thinks to become the various acne integrated use heat-clearing and toxic substances removing due to the one mutually because of heat, wet, expectorant, the stasis of blood, poison to the traditional Chinese medical science, and the treatment Fang Ze of infiltration dampness removing, blood stasis-eliminating and stagnation-dissipating carries out making behind the science compatibility.
Below, foregoing of the present invention is described in further detail by the specific embodiment:
Concrete embodiment
Embodiment 1:
28 parts of Radix Scutellariaes, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Fructus Forsythiaes, 13 parts in Poria, 13 parts of Aloes, 13 parts of Flos Rosae Rugosaes
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 6-8 times of water gaging to be decocted twice, be respectively 1.5 hours, 1 hour, filter, merge extractive liquid,, vacuum drying gets dry extract, pulverizes, cross 800 mesh sieves, add then and the distilled water of injection volume, stir into pasty state, be prepared into unguentum and get final product than 1: 1.
Embodiment 2:
26 parts of Radix Scutellariaes, 18 parts of Radix Salviae Miltiorrhizaes, 20 parts of Fructus Forsythiaes, 11 parts in Poria, 14 parts of Aloes, 14 parts of Flos Rosae Rugosaes
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 6-8 times of water gaging to be decocted twice, be respectively 1.5 hours, 1 hour, filter, merge extractive liquid,, vacuum drying gets dry extract, pulverizes, cross 800 mesh sieves, add then and the distilled water of injection volume, stir into pasty state, be prepared into unguentum and get final product than 1: 1.
Embodiment 3:
28 parts of Radix Scutellariaes, 20 parts of Radix Salviae Miltiorrhizaes, 18 parts of Fructus Forsythiaes, 12 parts in Poria, 15 parts of Aloes, 11 parts of Flos Rosae Rugosaes
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 8 times of water gagings to be decocted 1.5 hours, adding 6 times of water gagings for twice decocted 1 hour, filter, merge extractive liquid,, vacuum drying gets dry extract, pulverizes, cross 800 mesh sieves, add then and the distilled water of injection volume, stir into pasty state, be prepared into unguentum and get final product than 1: 1.
Embodiment 4:
26 parts of Radix Scutellariaes, 18 parts of Radix Salviae Miltiorrhizaes, 18 parts of Fructus Forsythiaes, 13 parts in Poria, 14 parts of Aloes, 14 parts of Flos Rosae Rugosaes
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 8 times of water gagings to be decocted 1.5 hours, adding 6 times of water gagings for twice decocted 1 hour, filter, merge extractive liquid,, vacuum drying gets dry extract, pulverizes, cross 800 mesh sieves, add then and the distilled water of injection volume, stir into pasty state, be prepared into unguentum and get final product than 1: 1.
Further set forth the beneficial effect of pharmaceutical composition of the present invention by following experiment.
In order to show that pharmaceutical composition of the present invention is to the remedy of acne effect, systematically selected the case of patients with acne of all ages and classes different sexes of pimple, pustular, nodositas, cyst, utilize medicine of the present invention to treat, be 30 days a course of treatment.
Criterion of therapeutical effect:
1, the criterion of therapeutical effect of judging for pimple, acne nodosum
Cure: pimple, tuberosity disappear fully, and transference cure does not have recurrence in 1 year.
Produce effects: skin lesion disappears more than 80%, and symptom disappears substantially, does not have recurrence in 1 year.
Effectively: skin lesion disappears more than 60%, and symptom is most of to disappear, and does not have recurrence in 1 year.
Invalid: the skin lesion less than 20% that disappears, symptom does not have obvious improvement, or recurrence is as before in 1 year after the drug withdrawal.
2, the criterion of therapeutical effect of judging for pustular, acne cystica
Cure: pustule, cyst etc. disappears fully, and transference cure does not have recurrence in 2 years.
Produce effects: skin lesion disappears more than 80%, and symptom disappears substantially, does not have recurrence in 2 years.
Effectively: skin lesion disappears more than 60%, and symptom is most of to disappear, and does not have recurrence in 2 years.
Invalid: the skin lesion less than 20% that disappears, symptom does not have obvious improvement, or recurrence is as before in 2 years after the drug withdrawal.
The concrete outcome 1-4 that sees the following form.
The clinical data statistics of the therapeutic effect of table 1 acne papulosa
The clinical data statistics of the therapeutic effect of table 2 acne nodosum
The clinical data statistics of the therapeutic effect of table 3 pustular acne
The clinical data statistics of the therapeutic effect of table 4 acne cystica
Treating various types of acne effective percentage more than 90% by the visible medicine of the present invention of above clinical statistics data, and instant effect, good effect is difficult for recurrence, and toxic and side effects is little.Therefore, pharmaceutical composition of the present invention has the effect of the acne of well dispelling.
Claims (6)
1. the pharmaceutical composition with acne-dispelling function is characterized in that, it is to be made by following bulk drugs: Radix Scutellariae 15-40 part, Radix Salviae Miltiorrhizae 10-30 part, Fructus Forsythiae 10-30 part, Poria 5-20 part, Aloe 5-20 part, Flos Rosae Rugosae 5-20 part.
2. pharmaceutical composition according to claim 1 is characterized in that, it is to be made by following bulk drugs: Radix Scutellariae 25-30 part, Radix Salviae Miltiorrhizae 18-22 part, Fructus Forsythiae 18-22 part, Poria 10-15 part, Aloe 10-15 part, Flos Rosae Rugosae 10-15 part.
3. according to claim 1 or 2 described pharmaceutical compositions, it is characterized in that described medicament is a unguentum.
4. according to claim 1 or 2 or 3 described preparation of drug combination methods, it is characterized in that this method is:
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are decocted with water twice, filter, merge extractive liquid,, drying is pulverized, and sieves, and adds distilled water then, stirs into pasty state, is prepared into unguentum and gets final product.
5. according to the described preparation of drug combination method of claim 3, it is characterized in that this method is:
Radix Scutellariae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Poria, Aloe, Flos Rosae Rugosae are added 6-8 times of water gaging decoct twice, be respectively 1.5 hours, 1 hour, filter merge extractive liquid,, vacuum drying gets dry extract, pulverizes, and crosses 800 mesh sieves, add distilled water then, stir into pasty state, be prepared into unguentum and get final product.
6. claim 1 or 2 described pharmaceutical compositions are used to prepare the medicine with acne-dispelling function or the application of health food.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100862214A CN101897865A (en) | 2009-05-27 | 2009-05-27 | Medicinal composition with function of removing acne and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100862214A CN101897865A (en) | 2009-05-27 | 2009-05-27 | Medicinal composition with function of removing acne and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN101897865A true CN101897865A (en) | 2010-12-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100862214A Pending CN101897865A (en) | 2009-05-27 | 2009-05-27 | Medicinal composition with function of removing acne and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908602A (en) * | 2012-11-07 | 2013-02-06 | 南京慧博生物科技有限公司 | Medicinal composition with acne-removing effect and preparation method thereof |
| CN103099885A (en) * | 2011-11-14 | 2013-05-15 | 甘肃创兴生物工程有限责任公司 | Soft capsules having acne removing function and preparation method thereof |
| CN105412415A (en) * | 2015-12-21 | 2016-03-23 | 荥阳市藤本保健品有限公司 | Medicine composition removing acnes |
| CN107308017A (en) * | 2016-04-26 | 2017-11-03 | 珠海宝德润生健康科技有限公司 | A kind of composition with acne-removal function and preparation method thereof |
| CN108420938A (en) * | 2018-03-30 | 2018-08-21 | 山西中医药大学 | It is a kind of can repair, the Chinese medicine composition of skin whitening and its medicament preparation method |
-
2009
- 2009-05-27 CN CN2009100862214A patent/CN101897865A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099885A (en) * | 2011-11-14 | 2013-05-15 | 甘肃创兴生物工程有限责任公司 | Soft capsules having acne removing function and preparation method thereof |
| CN102908602A (en) * | 2012-11-07 | 2013-02-06 | 南京慧博生物科技有限公司 | Medicinal composition with acne-removing effect and preparation method thereof |
| CN105412415A (en) * | 2015-12-21 | 2016-03-23 | 荥阳市藤本保健品有限公司 | Medicine composition removing acnes |
| CN107308017A (en) * | 2016-04-26 | 2017-11-03 | 珠海宝德润生健康科技有限公司 | A kind of composition with acne-removal function and preparation method thereof |
| CN108420938A (en) * | 2018-03-30 | 2018-08-21 | 山西中医药大学 | It is a kind of can repair, the Chinese medicine composition of skin whitening and its medicament preparation method |
| CN108420938B (en) * | 2018-03-30 | 2021-05-04 | 山西中医药大学 | Traditional Chinese medicine composition capable of repairing and whitening skin and preparation method of medicine thereof |
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Application publication date: 20101201 |