CN104815101A - Externally used medicine for treating climacteric syndrome and preparation method thereof - Google Patents

Externally used medicine for treating climacteric syndrome and preparation method thereof Download PDF

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CN104815101A
CN104815101A CN201510255224.1A CN201510255224A CN104815101A CN 104815101 A CN104815101 A CN 104815101A CN 201510255224 A CN201510255224 A CN 201510255224A CN 104815101 A CN104815101 A CN 104815101A
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radix
medicine
climacteric syndrome
fructus
used medicine
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张吉玲
林美蓉
孙世成
于进超
丛榕
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Abstract

The invention discloses an externally used medicine for treating climacteric syndrome and a preparation method thereof and belongs to the technical field of traditional Chinese medicine. The externally used medicine for treating climacteric syndrome is prepared from the following raw materials by weight: 10-15g of folium artemisiae argyi, 20-30g of motherwort, 10-15g of amethyst, 15-20g of cornu cervi degelatinatum, 10-15g of angelica, 10-15g of radix rehmanniae recen, 3-6g of American ginseng, 10-15g of wolfberry, 10-15g of fennel, 10-15g of rehmanniae vaporata, 10-15g of rhizoma acori graminei, 10-15g of Eucommia ulmoides, 10-15g of white paeony root, 20-30g of Eclipta alba, 10-15g of glossy privet fruit, 10-15g of oyster, 2-5g of shaved cinnamon bark, 6-9 g of fructus psoraleae and 10-12 g of walnut meat.

Description

External used medicine for the treatment of climacteric syndrome and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of climacteric syndrome, be specifically related to a kind of external used medicine for the treatment of climacteric syndrome and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Climacteric syndrome is the series of symptoms caused by decrease in estrogen.Climacteric women, due to hypo-ovaria, hyperpituitarism, the promoting sexual gland hormone of supersecretion, causes autonomic nervous dysfunction, thus occurs the symptom that a series of degree is different.
The medicine of current treatment climacteric syndrome is a lot, and Western medicine aspect is generally hormone therapy, and improper use can produce very large side effect; Also having some external hormones to paste, there is irritated or skin ulceration problem in it.
Summary of the invention
For above shortcomings in prior art, the invention provides the external used medicine that a kind of therapeutic effect is good, climacteric syndrome is treated in medication easily.
Of the present inventionly also provide that a kind of technique is simple, the preparation method of the external used medicine of the above-mentioned treatment climacteric syndrome of Be very effective.
The present invention adopts technical scheme as follows:
Treat an external used medicine for climacteric syndrome, the raw material comprising following weight is made: Folium Artemisiae Argyi 10-15 g, Herba Leonuri 20-30 g, Fluoritum 10-15 g, Cornu Cervi Degelatinatum 15-20 g, Radix Angelicae Sinensis 10-15 g, Radix Rehmanniae 10-15 g, Radix Panacis Quinquefolii 3-6 g, Fructus Lycii 10-15 g, Fructus Foeniculi 10-15 g, Radix Rehmanniae Preparata 10-15 g, Rhizoma Acori Graminei 10-15 g, Cortex Eucommiae 10-15 g, Radix Paeoniae Alba 10-15 g, Herba Ecliptae 20-30 g, Fructus Ligustri Lucidi 10-15 g, Concha Ostreae 10-15 g, Cortex Cinnamomi 2-5 g, Fructus Psoraleae 6-9 g, Semen Juglandis 10-12 g.
The external used medicine of above-mentioned treatment climacteric syndrome, it also comprises fumigating medicine, the raw material that fumigating medicine comprises following weight portion is made: Radix Glycyrrhizae 5g, Poria 20g, Radix Salviae Miltiorrhizae 20g, Semen Plantaginis 15g, Radix Dipsaci 25g, Radix Angelicae Sinensis 15g, Poria cum Radix Pini 15g, Fructus Alpiniae Oxyphyllae 20g, Semen Raphani 12.5g, Cortex Jujubae 10g.
Treat an external used medicine preparation method for climacteric syndrome, comprise the following steps: by all dry drugs by drug ratio fried dry to brown color, porphyrize 200 mesh sieve mixing for subsequent use; Enter in pot by 1000g Mel, add 30g Ramulus Persicae and temper to a large amount of fine and smooth foam of appearance, color transfers red sauce to for degree, removes Ramulus Persicae; The Mel of tempering is poured in said medicine powder, stir with Ramulus Persicae, rub and be pressed into plaster.
Using method: plaster is placed in food steamer, fumigates plaster with fumigant.Stick position: the plaster fumigated spreads on ventral groove portion, often stick 2 one 3 days and be advisable, 4 subsides are 1 course for the treatment of.
Prescription analysis:
The external used medicine for the treatment of climacteric syndrome: Folium Artemisiae Argyi: can dispersing cold for relieving pain, warming the meridian for stopping bleeding.Herba Leonuri: the effect with blood circulation promoting and blood stasis dispelling, regulating menstruation diuretic, promoting tissue regeneration by removing blood stasis, reducing swelling and alleviating pain.Fluoritum: tranquilizing mind, warming the lung, warm palace, for insomnia and dreamful sleep, palpitation and being susceptible to fright, cough and asthma due to lung deficiency, infertility.Cornu Cervi Degelatinatum: tonify deficiency, supporing yang, control insufficiency of kidney-YANG, ache of the spinal column, Deficiency and coldness of spleen and stomach, vomiting, anorexia and loose stool, deficiency-cold of uterus, bleeding not during menses.Radix Angelicae Sinensis: be both the key medicine that nourishes blood also is invigorate blood circulation to act on stronger medicine.Radix Rehmanniae controls fever due to yin deficiency, quenches one's thirst, and spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.Radix Panacis Quinquefolii: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid, lose for deficiency of vital energy the moon, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done, and lung benefiting is cloudy, clear asthenic fire, promoting the production of body fluid to quench thirst.Fructus Lycii: nourishing the liver, nourishing kidney, lung moistening.Fructus Foeniculi: the effect with cold-dispelling pain-relieving, has good curative effect to uterus deficiency and coldness, back cold type of pain, tripe distention and fullness in the abdomen, soft stool and the hernia etc. that cold-damp, the stagnation of QI cause.Radix Rehmanniae Preparata: yin nourishing of enriching blood, life essence-filling, marrow-benefitting.The Cortex Eucommiae: liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive effect, can treat the lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes is solid, the diseases such as scrotum pruritus due to damp pathogen.The Radix Paeoniae Alba: nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing the hyperactive liver sun, for menoxenia, abdominal pain during menstruation, metrorrhagia, and the disease such as spontaneous perspiration, night sweat.Herba Ecliptae: nourishing YIN for benefiting the kidney, cooling blood for hemostasis, Fructus Ligustri Lucidi and Herba Ecliptae compatibility, the effect of its nourishing the liver and kidney can obviously be strengthened, and is the conventional prescription of the treatment by Chinese herbs liver-kidney yin deficiency of climacteric syndrome.Concha Ostreae: suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating; Main vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter, lump in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia, can liver-invigorating detoxication, improve New function, purification blood stasis, set up, improve immunity.Cortex Cinnamomi: mend fire supporing yang; Let the fire back to its origin; Dispersing cold for relieving pain; Warming the meridian and promoting blood circulation.Fructus Psoraleae: the function having kidney invigorating and YANG supporting, spleen reinforcing stomach invigorating.Semen Juglandis: tonifying the kidney to consolidate the essence, warming the lung Dingchuan, loosening bowel to relieve constipation; For suffering from a deficiency of the kidney, soreness of waist foot is soft, impotence and seminal emission, cough with asthma of asthenia cold type, chronic cough of deficiency lung, the diseases such as dryness of the intestine constipation.Rhizoma Acori Graminei: regulate the flow of vital energy, invigorates blood circulation, and loose wind, dries.
Fumigating medicine: Radix Glycyrrhizae: invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, eliminating fire and detoxication, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; Modern medicine study shows, Radix Glycyrrhizae has antiviral, antiinflammatory, effect of protecting the liver, can be used for treating insufficiency of the spleen, cough and asthma, laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore etc.Poria: for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle, and for obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.Semen Plantaginis: diuretic, heat clearing away, improving eyesight, eliminates the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Radix Dipsaci invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating, controls aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, and carbuncle skin ulcer swells.Poria cum Radix Pini controls palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, dysuria, and spirit is supported in happy Fructus Alpiniae Oxyphyllae.Fructus Alpiniae Oxyphyllae: Deficiency and coldness of spleen and stomach, vomiting, has loose bowels, and coldly in abdomen educates, the many salivas of mouth, enuresis due to deficiency of the kidney, frequent micturition, seminal emission, nebulousurine, the diseases such as many salivas.Semen Raphani: for retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.Cortex Jujubae: astringing to arrest diarrhea, eliminates the phlegm, antitussive, antiinflammatory, hemostasis.
Be clinical trial results of the present invention below:
1. clinical research
Therapeutic Method: matched group adopts estrogen to paste: be directly affixed on by Estracomb on the skin of hypogastric region or buttocks, can change dressings 1 time every 4 days, continuous use 8 is 1 course for the treatment of.After using 4 tablets of these medicines continuously, should start to add medroxyprogestetone acetate sheet, daily 3 ~ 4.Directly be affixed on by Estracomb on the skin of hypogastric region or buttocks, can change dressings 1 time every 4 days, continuous use 8 is 1 course for the treatment of.After using 4 tablets of these medicines continuously, should start to add medroxyprogestetone acetate sheet, daily 3 ~ 4.Treatment group adopts medicine docile of the present invention, often sticks 2 one 3 days and is advisable.4 subsides are 1 course for the treatment of.
The analysis of front and back curative effect treated by table 1
Result shows: two groups of comparitive study: in matched group 40 example, effective 16 examples, effective 12 examples, invalid 12 examples, and total effective rate is 52.5%; In 40 examples for the treatment of group, effective 35 examples, effective 3 examples, invalid 2 examples, total effective rate is 95%.
Treatment group remission status observe: patients symptomatic relief is better than matched group at the time, particularly medication 5 days, 7 days time, all demonstrate better curative effect.
Model case: aaa
King's ××, female, 52 years old, interval amenorrhea, Sleep hyperhidrosis, headache, dizziness, palpitating speed, uncomfortable in chest, emotional instability, irritability.Continuous use medicine of the present invention is after one week, and symptom alleviates, and emotion is steady; After using two weeks, the eumenorrhea rises, and is emotionally stable, and heart beating is steady.
Liu's ××, female, 48 years old, premature menopause, trick was sent out cool, agitation, irritability, depressed, dyspareunia, pudendal pruritus.Continuous use medicine of the present invention is after one week, and symptom alleviates, and emotion is steady; Use after one month, the eumenorrhea rises, and sexual life recovers normal.
Certain female, 38 years old, menopause 2 years, dyspareunia, difficulty.Continuous use medicine of the present invention is after two weeks, and emotion is steady, and can have sexual intercourse activity; After using one and a half months, the eumenorrhea rises, and sexual life recovers normal; After half a year, make a definite diagnosis pregnancy.
Medicine of the present invention adopts Chinese medicine formula, and prescription compatibility is reasonable, by stifling docile mode by drug absorption, solve in the past that point-application medicament composing prescription is unclear, the problem of applying method complexity, solves the side effect that oral Chinese medicine brings, and adds the compliance of patient.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further details, but does not form any limitation of the invention, anyone change done within the scope of the claims in the present invention, still in protection scope of the present invention.
Embodiment 1
Treat an external used medicine for climacteric syndrome, the raw material comprising following weight portion is made: Folium Artemisiae Argyi 10g, Herba Leonuri 30 g, Fluoritum 15 g, Cornu Cervi Degelatinatum 15g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 12g, Radix Panacis Quinquefolii 4g, Fructus Lycii 10g, Fructus Foeniculi 15g, Radix Rehmanniae Preparata 10g, Rhizoma Acori Graminei 12g, Cortex Eucommiae 12g, Radix Paeoniae Alba 10g, Herba Ecliptae 20g, Fructus Ligustri Lucidi 15g, Concha Ostreae 10g, Cortex Cinnamomi 2g, Fructus Psoraleae 8g, Semen Juglandis 10g.
Embodiment 2
Treat an external used medicine for climacteric syndrome, the raw material comprising following weight portion is made: Folium Artemisiae Argyi 15g, Herba Leonuri 20 g, Fluoritum 10 g, Cornu Cervi Degelatinatum 18g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 10g, Radix Panacis Quinquefolii 6g, Fructus Lycii 15g, Fructus Foeniculi 12g, Radix Rehmanniae Preparata 15g, Rhizoma Acori Graminei 10g, Cortex Eucommiae 10g, Radix Paeoniae Alba 15g, Herba Ecliptae 26g, Fructus Ligustri Lucidi 12g, Concha Ostreae 15g, Cortex Cinnamomi 3.5g, Fructus Psoraleae 9g, Semen Juglandis 12g.
Embodiment 3
Treat an external used medicine for climacteric syndrome, the raw material comprising following weight portion is made: Folium Artemisiae Argyi 12g, Herba Leonuri 28 g, Fluoritum 12g, Cornu Cervi Degelatinatum 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 15g, Radix Panacis Quinquefolii 3g, Fructus Lycii 12g, Fructus Foeniculi 10 g, Radix Rehmanniae Preparata 12g, Rhizoma Acori Graminei 15g, Cortex Eucommiae 15g, Radix Paeoniae Alba 12g, Herba Ecliptae 30g, Fructus Ligustri Lucidi 10g, Concha Ostreae 12g, Cortex Cinnamomi 5g, Fructus Psoraleae 6g, Semen Juglandis 11g.
Also comprise fumigating medicine in embodiment 1 to 3, the raw material that fumigating medicine comprises following weight portion is made: Radix Glycyrrhizae 5g, Poria 20g, Radix Salviae Miltiorrhizae 20g, Semen Plantaginis 15g, Radix Dipsaci 25g, Radix Angelicae Sinensis 15g, Poria cum Radix Pini 15g, Fructus Alpiniae Oxyphyllae 20g, Semen Raphani 12.5g, Cortex Jujubae 10g.
Treat an external used medicine preparation method for climacteric syndrome described in embodiment 1 to 3, comprise the following steps: enter in pot by 1000g Mel, add 30g Ramulus Persicae and temper to a large amount of fine and smooth foam of appearance, color transfers red sauce to for degree, removes Ramulus Persicae; The Mel of tempering is poured in said medicine powder, stir with Ramulus Persicae, rub and be pressed into plaster.
Above-mentioned external used medicine applying method: plaster is placed in food steamer, fumigates plaster with fumigant.Concrete steps are: put by fumigating medicine in pot, add water appropriate, and plaster is placed on cage comb; Fumigating medicine starts to fumigate after boiling 3min, and general 40min-60min plaster is namely softening to be taken out.Stick position: ventral groove portion, with after 75% ethanol routine disinfection, spreads on ventral groove portion, then uses immobilization with adhesive tape, cloth hypersensitivity person fixes with lying in ventral groove portion with strap after gauze external application, often sticks 2 one 3 days and is advisable.4 subsides are 1 course for the treatment of.

Claims (3)

1. treat the external used medicine of climacteric syndrome for one kind, it is characterized in that, the raw material comprising following weight is made: Folium Artemisiae Argyi 10-15 g, Herba Leonuri 20-30 g, Fluoritum 10-15 g, Cornu Cervi Degelatinatum 15-20 g, Radix Angelicae Sinensis 10-15 g, Radix Rehmanniae 10-15 g, Radix Panacis Quinquefolii 3-6 g, Fructus Lycii 10-15 g, Fructus Foeniculi 10-15 g, Radix Rehmanniae Preparata 10-15 g, Rhizoma Acori Graminei 10-15 g, Cortex Eucommiae 10-15 g, Radix Paeoniae Alba 10-15 g, Herba Ecliptae 20-30 g, Fructus Ligustri Lucidi 10-15 g, Concha Ostreae 10-15 g, Cortex Cinnamomi 2-5 g, Fructus Psoraleae 6-9 g, Semen Juglandis 10-12 g.
2. treat the external used medicine of climacteric syndrome according to claim 1, it is characterized in that, it also comprises fumigating medicine, the raw material that fumigating medicine comprises following weight portion is made: Radix Glycyrrhizae 5g, Poria 20g, Radix Salviae Miltiorrhizae 20g, Semen Plantaginis 15g, Radix Dipsaci 25g, Radix Angelicae Sinensis 15g, Poria cum Radix Pini 15g, Fructus Alpiniae Oxyphyllae 20g, Semen Raphani 12.5g, Cortex Jujubae 10g.
3. treat an external used medicine preparation method for climacteric syndrome described in claim 1, it is characterized in that: comprise the following steps: by all dry drugs by drug ratio fried dry to brown color, porphyrize 200 mesh sieve mixing for subsequent use; Enter in pot by 1000g Mel, add 30g Ramulus Persicae and temper to a large amount of fine and smooth foam of appearance, color transfers red sauce to for degree, removes Ramulus Persicae; The Mel of tempering is poured in said medicine powder, stir with Ramulus Persicae, rub and be pressed into plaster.
CN201510255224.1A 2015-05-19 2015-05-19 Externally used medicine for treating climacteric syndrome and preparation method thereof Pending CN104815101A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106890085A (en) * 2017-01-23 2017-06-27 安徽绿莹彩龙艾绒制药有限公司 A kind of medicine moxa-moxibustion of moxibustion climacteric metancholia
CN111067957A (en) * 2018-10-22 2020-04-28 广西小咕噜生物科技有限公司 External traditional Chinese medicine ointment for treating liver depression and qi stagnation type climacteric syndrome

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103070930A (en) * 2013-01-25 2013-05-01 单文周 Spray for treating climacteric syndrome

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103070930A (en) * 2013-01-25 2013-05-01 单文周 Spray for treating climacteric syndrome

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106890085A (en) * 2017-01-23 2017-06-27 安徽绿莹彩龙艾绒制药有限公司 A kind of medicine moxa-moxibustion of moxibustion climacteric metancholia
CN111067957A (en) * 2018-10-22 2020-04-28 广西小咕噜生物科技有限公司 External traditional Chinese medicine ointment for treating liver depression and qi stagnation type climacteric syndrome

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Application publication date: 20150805