KR20220044551A - Apoc3-관련 질환 및 장애의 치료 방법 - Google Patents

Apoc3-관련 질환 및 장애의 치료 방법 Download PDF

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KR20220044551A
KR20220044551A KR1020227007372A KR20227007372A KR20220044551A KR 20220044551 A KR20220044551 A KR 20220044551A KR 1020227007372 A KR1020227007372 A KR 1020227007372A KR 20227007372 A KR20227007372 A KR 20227007372A KR 20220044551 A KR20220044551 A KR 20220044551A
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South Korea
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dose
pharmaceutical composition
apoc3
apoc3 rnai
administered
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KR1020227007372A
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Korean (ko)
Inventor
브루스 디. 기븐
제임스 씨. 해밀턴
스테이시 멜퀴스트
젠 리
뤼 주
타오 페이
스티븐 칸너
소 웡
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애로우헤드 파마슈티컬스 인코포레이티드
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Publication of KR20220044551A publication Critical patent/KR20220044551A/ko
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    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
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  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227007372A 2019-08-05 2020-08-04 Apoc3-관련 질환 및 장애의 치료 방법 Pending KR20220044551A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962883046P 2019-08-05 2019-08-05
US62/883,046 2019-08-05
US201962936559P 2019-11-17 2019-11-17
US62/936,559 2019-11-17
US202062970613P 2020-02-05 2020-02-05
US62/970,613 2020-02-05
PCT/US2020/044879 WO2021026150A1 (en) 2019-08-05 2020-08-04 Methods for the treatment of apoc3-related diseases and disorders

Publications (1)

Publication Number Publication Date
KR20220044551A true KR20220044551A (ko) 2022-04-08

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KR1020227007372A Pending KR20220044551A (ko) 2019-08-05 2020-08-04 Apoc3-관련 질환 및 장애의 치료 방법

Country Status (9)

Country Link
US (1) US20220152079A1 (https=)
EP (1) EP4010075A4 (https=)
JP (2) JP7829478B2 (https=)
KR (1) KR20220044551A (https=)
CN (1) CN114555188A (https=)
CA (1) CA3147725A1 (https=)
MX (1) MX2022001460A (https=)
TW (1) TW202120104A (https=)
WO (1) WO2021026150A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026049536A1 (en) * 2024-08-30 2026-03-05 Olix Pharmaceuticals, Inc. RNAi AGENT TARGETING APOC3 GENE AND USE THEREOF

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201901841TA (en) * 2016-09-02 2019-03-28 Arrowhead Pharmaceuticals Inc Targeting ligands
CN114934074A (zh) * 2022-06-01 2022-08-23 北京大学 一种ApoC3基因敲除仓鼠模型的构建方法
AU2024280172A1 (en) 2023-06-01 2025-12-04 Sunshine Lake Pharma Co., Ltd. Novel double-stranded sirna, conjugate thereof, and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101383006B1 (ko) * 2009-02-10 2014-04-08 아마린 파마, 인크. 고중성지방혈증 치료 방법
MX390699B (es) * 2011-06-21 2025-03-21 Alnylam Pharmaceuticals Inc Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).
EP2723758B1 (en) * 2011-06-21 2018-06-20 Alnylam Pharmaceuticals, Inc. Angiopoietin-like 3 (angptl3) irna compostions and methods of use thereof
JP2017535552A (ja) * 2014-11-17 2017-11-30 アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． アポリポタンパク質Ｃ３（ＡＰＯＣ３）ｉＲＮＡ組成物およびその使用方法
WO2018112320A1 (en) * 2016-12-16 2018-06-21 Alnylam Pharmaceuticals, Inc. Methods for treating or preventing ttr-associated diseases using transthyretin (ttr) irna compositions
CN120330183A (zh) * 2017-06-02 2025-07-18 波涛生命科学有限公司 寡核苷酸组合物及其使用方法
KR20240161202A (ko) * 2017-09-11 2024-11-12 애로우헤드 파마슈티컬스 인코포레이티드 아포지단백질 C-III (APOC3)의 발현을 억제하기 위한 RNAi 작용제 및 조성물
EP3719127A4 (en) * 2017-12-01 2021-10-20 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, COMPOSITION AND CONJUGATE WITH IT, MANUFACTURING METHOD AND USE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026049536A1 (en) * 2024-08-30 2026-03-05 Olix Pharmaceuticals, Inc. RNAi AGENT TARGETING APOC3 GENE AND USE THEREOF

Also Published As

Publication number Publication date
MX2022001460A (es) 2022-02-22
CN114555188A (zh) 2022-05-27
WO2021026150A1 (en) 2021-02-11
AU2020324974A1 (en) 2022-02-24
CA3147725A1 (en) 2021-02-11
JP2022543136A (ja) 2022-10-07
JP7829478B2 (ja) 2026-03-13
EP4010075A4 (en) 2023-11-15
TW202120104A (zh) 2021-06-01
JP2025061882A (ja) 2025-04-11
US20220152079A1 (en) 2022-05-19
EP4010075A1 (en) 2022-06-15

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