KR20220020993A - 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법 - Google Patents

면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법 Download PDF

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KR20220020993A
KR20220020993A KR1020227002915A KR20227002915A KR20220020993A KR 20220020993 A KR20220020993 A KR 20220020993A KR 1020227002915 A KR1020227002915 A KR 1020227002915A KR 20227002915 A KR20227002915 A KR 20227002915A KR 20220020993 A KR20220020993 A KR 20220020993A
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protein
fragment
antigen
cells
cell
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Korean (ko)
Inventor
마티아스 보르메어
우구르 사힌
바르바라 쉬뢰르스
마르틴 뢰버
세바스티안 뵈겔
Original Assignee
비온테크 에스이
트론-트란슬라셔날레 온콜로기 안 데어 유니버시태츠메디진 데어 요하네스 구텐베르크-유니버시태트 마인츠 게마인뉘치게 게엠베하
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Application filed by 비온테크 에스이, 트론-트란슬라셔날레 온콜로기 안 데어 유니버시태츠메디진 데어 요하네스 구텐베르크-유니버시태트 마인츠 게마인뉘치게 게엠베하 filed Critical 비온테크 에스이
Priority to KR1020247031632A priority Critical patent/KR20240146087A/ko
Publication of KR20220020993A publication Critical patent/KR20220020993A/ko
Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4712Muscle proteins, e.g. myosin, actin, protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
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  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020227002915A 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법 Ceased KR20220020993A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247031632A KR20240146087A (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2016/060897 WO2017194170A1 (en) 2016-05-13 2016-05-13 Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
EPPCT/EP2016/060897 2016-05-13
PCT/EP2017/061196 WO2017194610A1 (en) 2016-05-13 2017-05-10 Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
KR1020187032652A KR102358620B1 (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

Related Parent Applications (1)

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KR1020187032652A Division KR102358620B1 (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

Related Child Applications (1)

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KR1020247031632A Division KR20240146087A (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

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KR20220020993A true KR20220020993A (ko) 2022-02-21

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KR1020227002915A Ceased KR20220020993A (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법
KR1020187032652A Active KR102358620B1 (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법
KR1020247031632A Pending KR20240146087A (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

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KR1020187032652A Active KR102358620B1 (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법
KR1020247031632A Pending KR20240146087A (ko) 2016-05-13 2017-05-10 면역 치료를 위한 단백질 또는 단백질 단편의 유용성 예측 방법

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US (2) US12153041B2 (https=)
EP (3) EP4411376A3 (https=)
JP (5) JP7529381B2 (https=)
KR (3) KR20220020993A (https=)
CN (1) CN109073637A (https=)
AU (2) AU2017264546B2 (https=)
BR (1) BR112018073221A2 (https=)
CA (1) CA3022654A1 (https=)
CY (1) CY1123520T1 (https=)
DK (2) DK3792628T3 (https=)
ES (2) ES2826480T3 (https=)
FI (1) FI3792628T3 (https=)
HR (2) HRP20240704T1 (https=)
HU (2) HUE067497T2 (https=)
IL (2) IL300841A (https=)
LT (2) LT3455625T (https=)
MA (1) MA43794B1 (https=)
MD (1) MD3455625T2 (https=)
MX (2) MX393653B (https=)
PL (2) PL3455625T3 (https=)
PT (2) PT3792628T (https=)
RS (2) RS65568B1 (https=)
SG (1) SG11201808495SA (https=)
SI (2) SI3792628T1 (https=)
SM (2) SMT202400232T1 (https=)
WO (2) WO2017194170A1 (https=)
ZA (1) ZA201805809B (https=)

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EP3933408A1 (en) 2017-05-30 2022-01-05 Nant Holdings IP LLC Circulating tumor cell enrichment using neoepitopes
JP6857930B2 (ja) * 2018-02-15 2021-04-14 国立大学法人旭川医科大学 がん抗原ペプチド
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US20220349010A1 (en) 2018-07-26 2022-11-03 Frame Pharmaceuticals B.V. Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database
CN109021062B (zh) * 2018-08-06 2021-08-20 倍而达药业(苏州)有限公司 一种肿瘤新抗原的筛选方法
CN111621564B (zh) * 2019-02-28 2022-03-25 武汉大学 一种鉴定有效肿瘤新抗原的方法
TWI894138B (zh) * 2019-03-06 2025-08-21 美商西雅圖項目公司 利用ii 類mhc 模型鑑別新抗原
CN110534156B (zh) * 2019-09-02 2022-06-17 深圳市新合生物医疗科技有限公司 一种提取免疫治疗新抗原的方法及系统
CN111487399B (zh) * 2020-03-26 2021-09-17 湖南师范大学 一种蛋白分子标记在鱼类生殖细胞发育研究中的应用
WO2023025404A1 (en) 2021-08-24 2023-03-02 BioNTech SE In vitro transcription technologies
WO2024083345A1 (en) 2022-10-21 2024-04-25 BioNTech SE Methods and uses associated with liquid compositions
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ES2826480T3 (es) 2021-05-18
PT3455625T (pt) 2020-10-22
HUE052240T2 (hu) 2021-04-28
IL262680B1 (en) 2023-04-01
RS61071B1 (sr) 2020-12-31
IL300841A (en) 2023-04-01
CN109073637A (zh) 2018-12-21
JP2022081492A (ja) 2022-05-31
AU2017264546B2 (en) 2022-04-28
US20250244311A1 (en) 2025-07-31
JP2024096712A (ja) 2024-07-17
EP3455625B1 (en) 2020-09-02
WO2017194610A1 (en) 2017-11-16
PL3792628T3 (pl) 2024-07-15
AU2022209286A1 (en) 2022-08-25
ZA201805809B (en) 2020-12-23
HUE067497T2 (hu) 2024-10-28
KR20240146087A (ko) 2024-10-07
KR102358620B1 (ko) 2022-02-07
EP3792628B1 (en) 2024-04-24
EP4411376A3 (en) 2025-03-19
FI3792628T3 (fi) 2024-06-07
KR20190008218A (ko) 2019-01-23
HRP20201671T1 (hr) 2021-03-05
RU2018137721A3 (https=) 2020-08-25
EP3792628A2 (en) 2021-03-17
US12153041B2 (en) 2024-11-26
DK3455625T3 (da) 2020-10-26
PL3455625T3 (pl) 2021-01-25
JP7529381B2 (ja) 2024-08-06
HRP20240704T1 (hr) 2024-09-27
LT3792628T (lt) 2024-06-25
EP3455625A1 (en) 2019-03-20
BR112018073221A2 (pt) 2019-02-19
SI3792628T1 (sl) 2024-08-30
MX2018013081A (es) 2019-01-24
DK3792628T3 (da) 2024-06-17
AU2017264546A1 (en) 2018-10-18
IL262680B2 (en) 2023-08-01
MX2022007902A (es) 2022-07-21
PT3792628T (pt) 2024-06-18
SMT202000622T1 (it) 2021-01-05
CA3022654A1 (en) 2017-11-16
IL262680A (en) 2018-12-31
US20190178871A1 (en) 2019-06-13
JP2024112805A (ja) 2024-08-21
SI3455625T1 (sl) 2021-01-29
JP2024160216A (ja) 2024-11-13
RS65568B1 (sr) 2024-06-28
MX393653B (es) 2025-03-24
SMT202400232T1 (it) 2024-07-09
SG11201808495SA (en) 2018-10-30
MD3455625T2 (ro) 2020-12-31
EP3792628A3 (en) 2021-05-19
CY1123520T1 (el) 2022-03-24
EP4411376A2 (en) 2024-08-07
ES2980781T3 (es) 2024-10-03
MA43794B1 (fr) 2020-12-31
MA43794A (fr) 2019-03-20
LT3455625T (lt) 2021-01-11
RU2018137721A (ru) 2020-06-15
WO2017194170A1 (en) 2017-11-16
JP2019520554A (ja) 2019-07-18

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