KR20220016177A - 트라이사이클릭 화합물 - Google Patents
트라이사이클릭 화합물 Download PDFInfo
- Publication number
- KR20220016177A KR20220016177A KR1020217042967A KR20217042967A KR20220016177A KR 20220016177 A KR20220016177 A KR 20220016177A KR 1020217042967 A KR1020217042967 A KR 1020217042967A KR 20217042967 A KR20217042967 A KR 20217042967A KR 20220016177 A KR20220016177 A KR 20220016177A
- Authority
- KR
- South Korea
- Prior art keywords
- optionally substituted
- alkyl
- compound
- unsubstituted
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C[C@](C=C1)*=C[C@@]([C@@]2*C2)C1C(Nc1ccccc1)=O Chemical compound C[C@](C=C1)*=C[C@@]([C@@]2*C2)C1C(Nc1ccccc1)=O 0.000 description 11
- HLZUNACCURILHM-UHFFFAOYSA-N C=NC(c(cc1Cl)ccc1[Br]=C)=O Chemical compound C=NC(c(cc1Cl)ccc1[Br]=C)=O HLZUNACCURILHM-UHFFFAOYSA-N 0.000 description 1
- JCQPNVJBGFIVDI-UHFFFAOYSA-N CC(C)c(cn[n]1-c2c3ccnc2)c1N(c1ccccc1)C3=O Chemical compound CC(C)c(cn[n]1-c2c3ccnc2)c1N(c1ccccc1)C3=O JCQPNVJBGFIVDI-UHFFFAOYSA-N 0.000 description 1
- WYUHXXJUDAJLGY-UHFFFAOYSA-N CC(C)c(cn[n]1C2=C3CCN(Cc(cc4)cc(C)c4OC)C2)c1N(c1ccccc1)C3=O Chemical compound CC(C)c(cn[n]1C2=C3CCN(Cc(cc4)cc(C)c4OC)C2)c1N(c1ccccc1)C3=O WYUHXXJUDAJLGY-UHFFFAOYSA-N 0.000 description 1
- NRLQFEPADPQJIJ-UHFFFAOYSA-N CC(C)c(cn[n]1C2=C3CCNC2)c1N(c1ccccc1)C3=O Chemical compound CC(C)c(cn[n]1C2=C3CCNC2)c1N(c1ccccc1)C3=O NRLQFEPADPQJIJ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962854597P | 2019-05-30 | 2019-05-30 | |
| US62/854,597 | 2019-05-30 | ||
| PCT/US2020/034746 WO2020243199A1 (en) | 2019-05-30 | 2020-05-27 | Tricyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20220016177A true KR20220016177A (ko) | 2022-02-08 |
Family
ID=73552666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217042967A Ceased KR20220016177A (ko) | 2019-05-30 | 2020-05-27 | 트라이사이클릭 화합물 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11136321B2 (https=) |
| EP (1) | EP3976618A4 (https=) |
| JP (1) | JP2022534501A (https=) |
| KR (1) | KR20220016177A (https=) |
| CN (1) | CN113906029A (https=) |
| AU (1) | AU2020282707B2 (https=) |
| BR (1) | BR112021023967A2 (https=) |
| CA (1) | CA3138938A1 (https=) |
| CL (1) | CL2021003139A1 (https=) |
| CO (1) | CO2021017202A2 (https=) |
| EA (1) | EA202192760A1 (https=) |
| IL (1) | IL287813A (https=) |
| MA (1) | MA56058A (https=) |
| MX (1) | MX2021014458A (https=) |
| PE (1) | PE20220427A1 (https=) |
| PH (1) | PH12021552953A1 (https=) |
| SG (1) | SG11202113214QA (https=) |
| TW (1) | TW202110845A (https=) |
| WO (1) | WO2020243199A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220000874A1 (en) * | 2019-05-30 | 2022-01-06 | Aligos Therapeutics, Inc. | Tricyclic compounds |
| TWI886184B (zh) * | 2019-12-10 | 2025-06-11 | 大陸商上海翰森生物醫藥科技有限公司 | 含吡唑多環類衍生物抑制劑、其製備方法和應用 |
| GB202103704D0 (en) * | 2021-03-17 | 2021-04-28 | Pathios Therapeutics Ltd | Compounds |
| EP4251625A4 (en) * | 2020-11-24 | 2024-10-09 | Aligos Therapeutics, Inc. | Tricyclic compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0701273D0 (en) * | 2007-01-24 | 2007-02-28 | Angeletti P Ist Richerche Bio | New compounds |
| WO2008157273A1 (en) * | 2007-06-14 | 2008-12-24 | Smithkline Beecham Corporation | Chemical compounds |
| AU2013404035B2 (en) * | 2013-10-29 | 2017-04-20 | Medivir Ab | Quinazoline based respiratory syncytial virus inhibitors |
| CO2018009382A2 (es) | 2016-03-09 | 2018-09-20 | Univ Emory | Eliminación del virus de la hepatitis b con agentes antivirales |
| CN110066278B (zh) * | 2017-06-01 | 2021-06-08 | 广东东阳光药业有限公司 | 稠合三环类化合物及其在药物中的应用 |
-
2020
- 2020-05-27 CN CN202080040114.2A patent/CN113906029A/zh active Pending
- 2020-05-27 JP JP2021570378A patent/JP2022534501A/ja active Pending
- 2020-05-27 KR KR1020217042967A patent/KR20220016177A/ko not_active Ceased
- 2020-05-27 EA EA202192760A patent/EA202192760A1/ru unknown
- 2020-05-27 CA CA3138938A patent/CA3138938A1/en active Pending
- 2020-05-27 US US16/885,128 patent/US11136321B2/en active Active
- 2020-05-27 PE PE2021001952A patent/PE20220427A1/es unknown
- 2020-05-27 EP EP20812759.7A patent/EP3976618A4/en not_active Withdrawn
- 2020-05-27 WO PCT/US2020/034746 patent/WO2020243199A1/en not_active Ceased
- 2020-05-27 BR BR112021023967A patent/BR112021023967A2/pt not_active IP Right Cessation
- 2020-05-27 AU AU2020282707A patent/AU2020282707B2/en not_active Expired - Fee Related
- 2020-05-27 PH PH1/2021/552953A patent/PH12021552953A1/en unknown
- 2020-05-27 MA MA056058A patent/MA56058A/fr unknown
- 2020-05-27 MX MX2021014458A patent/MX2021014458A/es unknown
- 2020-05-27 SG SG11202113214QA patent/SG11202113214QA/en unknown
- 2020-05-29 TW TW109118090A patent/TW202110845A/zh unknown
-
2021
- 2021-11-03 IL IL287813A patent/IL287813A/en unknown
- 2021-11-25 CL CL2021003139A patent/CL2021003139A1/es unknown
- 2021-12-15 CO CONC2021/0017202A patent/CO2021017202A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020243199A1 (en) | 2020-12-03 |
| MA56058A (fr) | 2022-04-06 |
| EP3976618A4 (en) | 2023-01-04 |
| US11136321B2 (en) | 2021-10-05 |
| PH12021552953A1 (en) | 2022-07-25 |
| SG11202113214QA (en) | 2021-12-30 |
| JP2022534501A (ja) | 2022-08-01 |
| BR112021023967A2 (pt) | 2022-03-08 |
| EA202192760A1 (ru) | 2022-03-05 |
| PE20220427A1 (es) | 2022-03-29 |
| MX2021014458A (es) | 2022-01-06 |
| EP3976618A1 (en) | 2022-04-06 |
| CL2021003139A1 (es) | 2022-09-23 |
| CN113906029A (zh) | 2022-01-07 |
| AU2020282707A1 (en) | 2021-12-02 |
| US20200407361A1 (en) | 2020-12-31 |
| AU2020282707B2 (en) | 2025-06-19 |
| TW202110845A (zh) | 2021-03-16 |
| IL287813A (en) | 2022-01-01 |
| CO2021017202A2 (es) | 2022-01-17 |
| CA3138938A1 (en) | 2020-12-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102641566B1 (ko) | 바이사이클릭 및 트라이사이클릭 화합물 | |
| KR20220016177A (ko) | 트라이사이클릭 화합물 | |
| JP7710215B2 (ja) | ピロール化合物 | |
| US11952374B2 (en) | Bicyclic compounds | |
| US11957683B2 (en) | Bicyclic compounds | |
| KR20210126636A (ko) | 이환식 설폰아마이드 | |
| AU2021360496A9 (en) | Bicyclic compounds | |
| US20220000874A1 (en) | Tricyclic compounds | |
| AU2023353869A1 (en) | Bicyclic compounds | |
| AU2023255673A1 (en) | Bicyclic compounds | |
| WO2023205645A1 (en) | Bicyclic compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20211228 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20230920 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20231201 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20230920 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |