BR112021023967A2 - Compostos tricíclicos - Google Patents

Compostos tricíclicos

Info

Publication number
BR112021023967A2
BR112021023967A2 BR112021023967A BR112021023967A BR112021023967A2 BR 112021023967 A2 BR112021023967 A2 BR 112021023967A2 BR 112021023967 A BR112021023967 A BR 112021023967A BR 112021023967 A BR112021023967 A BR 112021023967A BR 112021023967 A2 BR112021023967 A2 BR 112021023967A2
Authority
BR
Brazil
Prior art keywords
pharmaceutically acceptable
tricyclic compounds
formula
methods
acceptable salts
Prior art date
Application number
BR112021023967A
Other languages
English (en)
Portuguese (pt)
Inventor
Sandrine Vendeville
Original Assignee
Aligos Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aligos Therapeutics Inc filed Critical Aligos Therapeutics Inc
Publication of BR112021023967A2 publication Critical patent/BR112021023967A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112021023967A 2019-05-30 2020-05-27 Compostos tricíclicos BR112021023967A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962854597P 2019-05-30 2019-05-30
PCT/US2020/034746 WO2020243199A1 (en) 2019-05-30 2020-05-27 Tricyclic compounds

Publications (1)

Publication Number Publication Date
BR112021023967A2 true BR112021023967A2 (pt) 2022-03-08

Family

ID=73552666

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021023967A BR112021023967A2 (pt) 2019-05-30 2020-05-27 Compostos tricíclicos

Country Status (19)

Country Link
US (1) US11136321B2 (https=)
EP (1) EP3976618A4 (https=)
JP (1) JP2022534501A (https=)
KR (1) KR20220016177A (https=)
CN (1) CN113906029A (https=)
AU (1) AU2020282707B2 (https=)
BR (1) BR112021023967A2 (https=)
CA (1) CA3138938A1 (https=)
CL (1) CL2021003139A1 (https=)
CO (1) CO2021017202A2 (https=)
EA (1) EA202192760A1 (https=)
IL (1) IL287813A (https=)
MA (1) MA56058A (https=)
MX (1) MX2021014458A (https=)
PE (1) PE20220427A1 (https=)
PH (1) PH12021552953A1 (https=)
SG (1) SG11202113214QA (https=)
TW (1) TW202110845A (https=)
WO (1) WO2020243199A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220000874A1 (en) * 2019-05-30 2022-01-06 Aligos Therapeutics, Inc. Tricyclic compounds
TWI886184B (zh) * 2019-12-10 2025-06-11 大陸商上海翰森生物醫藥科技有限公司 含吡唑多環類衍生物抑制劑、其製備方法和應用
GB202103704D0 (en) * 2021-03-17 2021-04-28 Pathios Therapeutics Ltd Compounds
EP4251625A4 (en) * 2020-11-24 2024-10-09 Aligos Therapeutics, Inc. Tricyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0701273D0 (en) * 2007-01-24 2007-02-28 Angeletti P Ist Richerche Bio New compounds
WO2008157273A1 (en) * 2007-06-14 2008-12-24 Smithkline Beecham Corporation Chemical compounds
AU2013404035B2 (en) * 2013-10-29 2017-04-20 Medivir Ab Quinazoline based respiratory syncytial virus inhibitors
CO2018009382A2 (es) 2016-03-09 2018-09-20 Univ Emory Eliminación del virus de la hepatitis b con agentes antivirales
CN110066278B (zh) * 2017-06-01 2021-06-08 广东东阳光药业有限公司 稠合三环类化合物及其在药物中的应用

Also Published As

Publication number Publication date
WO2020243199A1 (en) 2020-12-03
MA56058A (fr) 2022-04-06
EP3976618A4 (en) 2023-01-04
US11136321B2 (en) 2021-10-05
KR20220016177A (ko) 2022-02-08
PH12021552953A1 (en) 2022-07-25
SG11202113214QA (en) 2021-12-30
JP2022534501A (ja) 2022-08-01
EA202192760A1 (ru) 2022-03-05
PE20220427A1 (es) 2022-03-29
MX2021014458A (es) 2022-01-06
EP3976618A1 (en) 2022-04-06
CL2021003139A1 (es) 2022-09-23
CN113906029A (zh) 2022-01-07
AU2020282707A1 (en) 2021-12-02
US20200407361A1 (en) 2020-12-31
AU2020282707B2 (en) 2025-06-19
TW202110845A (zh) 2021-03-16
IL287813A (en) 2022-01-01
CO2021017202A2 (es) 2022-01-17
CA3138938A1 (en) 2020-12-03

Similar Documents

Publication Publication Date Title
BR112021019465A8 (pt) Compostos que têm como alvo prmt5
BR112022025037A2 (pt) Compostos antivirais para tratar infecções por coronavírus, picornavírus e norovírus
BR112021023967A2 (pt) Compostos tricíclicos
PH12021500014A1 (en) Fused ring compounds
BR112022000019A2 (pt) Composto da fórmula, composição farmacêutica e método de tratamento de câncer
BR112021009595A2 (pt) Terapia de combinação incluindo um inibidor de krasg12c e um ou mais agentes farmaceuticamente ativos adicionais para o tratamento de cânceres
BR112021019817A2 (pt) Compostos de pirrol
BR112018070677A2 (pt) inibidores de mcl-1 macrocíclicos para o tratamento de câncer
MX2024000299A (es) Compuestos antivirales.
EA202090052A1 (ru) Содержащие имидазол ингибиторы alk2 киназы
BR112019006047A2 (pt) compostos, um ou dois ou mais compostos, sal farmaceuticamente aceitável, sal metanossulfonato, inibidor de quinase ret, medicamento, usos do composto e de um composto, métodos para tratar ou prevenir câncer e para tratar ou prevenir câncer em um indivíduo, e, composição farmacêutica
BR112018015413A2 (pt) inibidores de indoleamina-2,3-dioxigenase (ido)
BR112021019007A2 (pt) Protacs que degradam o receptor de estrogênio
BR112018005861A2 (pt) derivados de ácido oleanólico modificado com c4 para a inibição de il-17 e outros usos
EA202190681A1 (ru) Амиды диметиламиноазетидина в качестве jak ингибиторов
BR112021011325A2 (pt) Derivados de rapamicina
MX2020013297A (es) Compuestos para el tratamiento o la prevencion de enfermedades hepaticas.
BR112022012281A2 (pt) Combinações
BR112022012280A2 (pt) Combinações
BR112022012283A2 (pt) Combinações
BR112019018615A2 (pt) compostos antimicrobianos, composições e usos dos mesmos
BR112018070514A2 (pt) composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição
EA201992090A1 (ru) ДЕЙТЕРИРОВАННЫЕ СОЕДИНЕНИЯ ИМИДАЗО[4,5-c]ХИНОЛИН-2-ОНА И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ РАКА
EA202191192A1 (ru) Кристаллические соли ингибитора плазменного калликреина
CO2019013254A2 (es) Compuestos bicíclicos 5,6-fusionados y composiciones para el tratamiento de enfermedades parasitarias

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2829 DE 25/03/2025.