EA202192760A1 - Трициклические соединения - Google Patents

Трициклические соединения

Info

Publication number
EA202192760A1
EA202192760A1 EA202192760A EA202192760A EA202192760A1 EA 202192760 A1 EA202192760 A1 EA 202192760A1 EA 202192760 A EA202192760 A EA 202192760A EA 202192760 A EA202192760 A EA 202192760A EA 202192760 A1 EA202192760 A1 EA 202192760A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutically acceptable
compound
tricyclic compounds
formula
methods
Prior art date
Application number
EA202192760A
Other languages
English (en)
Russian (ru)
Inventor
Сандрин Вендевилль
Original Assignee
Алигос Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алигос Терапьютикс, Инк. filed Critical Алигос Терапьютикс, Инк.
Publication of EA202192760A1 publication Critical patent/EA202192760A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA202192760A 2019-05-30 2020-05-27 Трициклические соединения EA202192760A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962854597P 2019-05-30 2019-05-30
PCT/US2020/034746 WO2020243199A1 (en) 2019-05-30 2020-05-27 Tricyclic compounds

Publications (1)

Publication Number Publication Date
EA202192760A1 true EA202192760A1 (ru) 2022-03-05

Family

ID=73552666

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192760A EA202192760A1 (ru) 2019-05-30 2020-05-27 Трициклические соединения

Country Status (19)

Country Link
US (1) US11136321B2 (https=)
EP (1) EP3976618A4 (https=)
JP (1) JP2022534501A (https=)
KR (1) KR20220016177A (https=)
CN (1) CN113906029A (https=)
AU (1) AU2020282707B2 (https=)
BR (1) BR112021023967A2 (https=)
CA (1) CA3138938A1 (https=)
CL (1) CL2021003139A1 (https=)
CO (1) CO2021017202A2 (https=)
EA (1) EA202192760A1 (https=)
IL (1) IL287813A (https=)
MA (1) MA56058A (https=)
MX (1) MX2021014458A (https=)
PE (1) PE20220427A1 (https=)
PH (1) PH12021552953A1 (https=)
SG (1) SG11202113214QA (https=)
TW (1) TW202110845A (https=)
WO (1) WO2020243199A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220000874A1 (en) * 2019-05-30 2022-01-06 Aligos Therapeutics, Inc. Tricyclic compounds
TWI886184B (zh) * 2019-12-10 2025-06-11 大陸商上海翰森生物醫藥科技有限公司 含吡唑多環類衍生物抑制劑、其製備方法和應用
GB202103704D0 (en) * 2021-03-17 2021-04-28 Pathios Therapeutics Ltd Compounds
EP4251625A4 (en) * 2020-11-24 2024-10-09 Aligos Therapeutics, Inc. Tricyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0701273D0 (en) * 2007-01-24 2007-02-28 Angeletti P Ist Richerche Bio New compounds
WO2008157273A1 (en) * 2007-06-14 2008-12-24 Smithkline Beecham Corporation Chemical compounds
AU2013404035B2 (en) * 2013-10-29 2017-04-20 Medivir Ab Quinazoline based respiratory syncytial virus inhibitors
CO2018009382A2 (es) 2016-03-09 2018-09-20 Univ Emory Eliminación del virus de la hepatitis b con agentes antivirales
CN110066278B (zh) * 2017-06-01 2021-06-08 广东东阳光药业有限公司 稠合三环类化合物及其在药物中的应用

Also Published As

Publication number Publication date
WO2020243199A1 (en) 2020-12-03
MA56058A (fr) 2022-04-06
EP3976618A4 (en) 2023-01-04
US11136321B2 (en) 2021-10-05
KR20220016177A (ko) 2022-02-08
PH12021552953A1 (en) 2022-07-25
SG11202113214QA (en) 2021-12-30
JP2022534501A (ja) 2022-08-01
BR112021023967A2 (pt) 2022-03-08
PE20220427A1 (es) 2022-03-29
MX2021014458A (es) 2022-01-06
EP3976618A1 (en) 2022-04-06
CL2021003139A1 (es) 2022-09-23
CN113906029A (zh) 2022-01-07
AU2020282707A1 (en) 2021-12-02
US20200407361A1 (en) 2020-12-31
AU2020282707B2 (en) 2025-06-19
TW202110845A (zh) 2021-03-16
IL287813A (en) 2022-01-01
CO2021017202A2 (es) 2022-01-17
CA3138938A1 (en) 2020-12-03

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