KR20210141930A - 염증성 질환의 치료를 위한 아미노산 유도체 - Google Patents
염증성 질환의 치료를 위한 아미노산 유도체 Download PDFInfo
- Publication number
- KR20210141930A KR20210141930A KR1020217026302A KR20217026302A KR20210141930A KR 20210141930 A KR20210141930 A KR 20210141930A KR 1020217026302 A KR1020217026302 A KR 1020217026302A KR 20217026302 A KR20217026302 A KR 20217026302A KR 20210141930 A KR20210141930 A KR 20210141930A
- Authority
- KR
- South Korea
- Prior art keywords
- optionally substituted
- compound
- alkyl
- mmol
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795549P | 2019-01-22 | 2019-01-22 | |
| US62/795,549 | 2019-01-22 | ||
| US201962871951P | 2019-07-09 | 2019-07-09 | |
| US62/871,951 | 2019-07-09 | ||
| PCT/US2020/014636 WO2020154420A2 (en) | 2019-01-22 | 2020-01-22 | Amino acid derivatives for the treatment of inflammatory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210141930A true KR20210141930A (ko) | 2021-11-23 |
Family
ID=69726748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217026302A KR20210141930A (ko) | 2019-01-22 | 2020-01-22 | 염증성 질환의 치료를 위한 아미노산 유도체 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20220081415A1 (zh) |
| EP (1) | EP3924349A2 (zh) |
| JP (1) | JP2022524571A (zh) |
| KR (1) | KR20210141930A (zh) |
| CN (1) | CN113614074A (zh) |
| AU (1) | AU2020211980A1 (zh) |
| BR (1) | BR112021014372A2 (zh) |
| CA (1) | CA3127246A1 (zh) |
| CL (1) | CL2021001944A1 (zh) |
| CO (1) | CO2021010931A2 (zh) |
| EC (1) | ECSP21062210A (zh) |
| IL (1) | IL284980A (zh) |
| MA (1) | MA54940A (zh) |
| MX (1) | MX2021008748A (zh) |
| SG (1) | SG11202107977TA (zh) |
| WO (1) | WO2020154420A2 (zh) |
| ZA (1) | ZA202105229B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210113184A (ko) | 2018-11-30 | 2021-09-15 | 코멧 테라퓨틱스, 인코포레이티드 | 사이클릭 판테테인 유도체 및 이들의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107288A (en) | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US6218390B1 (en) * | 1998-12-17 | 2001-04-17 | Synaptic Pharmaceutical Corporation | Morpholinone and morpholine derivatives and uses thereof |
| EP2424850A1 (en) * | 2009-05-01 | 2012-03-07 | Profectus Biosciences, Inc. | Benzamide and naphthamide derivatives inhibiting nuclear factor- kap pa (b) - (nf-kb) |
-
2020
- 2020-01-22 CN CN202080021880.4A patent/CN113614074A/zh active Pending
- 2020-01-22 US US17/424,455 patent/US20220081415A1/en active Pending
- 2020-01-22 SG SG11202107977TA patent/SG11202107977TA/en unknown
- 2020-01-22 CA CA3127246A patent/CA3127246A1/en active Pending
- 2020-01-22 BR BR112021014372-6A patent/BR112021014372A2/pt unknown
- 2020-01-22 MA MA054940A patent/MA54940A/fr unknown
- 2020-01-22 JP JP2021543302A patent/JP2022524571A/ja active Pending
- 2020-01-22 KR KR1020217026302A patent/KR20210141930A/ko unknown
- 2020-01-22 WO PCT/US2020/014636 patent/WO2020154420A2/en unknown
- 2020-01-22 EP EP20708296.7A patent/EP3924349A2/en active Pending
- 2020-01-22 MX MX2021008748A patent/MX2021008748A/es unknown
- 2020-01-22 AU AU2020211980A patent/AU2020211980A1/en active Pending
-
2021
- 2021-07-20 IL IL284980A patent/IL284980A/en unknown
- 2021-07-22 CL CL2021001944A patent/CL2021001944A1/es unknown
- 2021-07-23 ZA ZA2021/05229A patent/ZA202105229B/en unknown
- 2021-08-19 CO CONC2021/0010931A patent/CO2021010931A2/es unknown
- 2021-08-20 EC ECSENADI202162210A patent/ECSP21062210A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2021010931A2 (es) | 2022-01-17 |
| IL284980A (en) | 2021-09-30 |
| SG11202107977TA (en) | 2021-08-30 |
| US20220081415A1 (en) | 2022-03-17 |
| JP2022524571A (ja) | 2022-05-09 |
| CN113614074A (zh) | 2021-11-05 |
| CL2021001944A1 (es) | 2022-05-06 |
| WO2020154420A3 (en) | 2020-09-10 |
| WO2020154420A2 (en) | 2020-07-30 |
| AU2020211980A1 (en) | 2021-08-19 |
| ZA202105229B (en) | 2022-12-21 |
| WO2020154420A4 (en) | 2020-11-12 |
| EP3924349A2 (en) | 2021-12-22 |
| ECSP21062210A (es) | 2022-06-30 |
| BR112021014372A2 (pt) | 2021-09-28 |
| CA3127246A1 (en) | 2020-07-30 |
| MA54940A (fr) | 2021-12-22 |
| MX2021008748A (es) | 2022-01-24 |
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