KR20200081432A - 조백선 치료용 외부 제제 - Google Patents

조백선 치료용 외부 제제 Download PDF

Info

Publication number
KR20200081432A
KR20200081432A KR1020207015246A KR20207015246A KR20200081432A KR 20200081432 A KR20200081432 A KR 20200081432A KR 1020207015246 A KR1020207015246 A KR 1020207015246A KR 20207015246 A KR20207015246 A KR 20207015246A KR 20200081432 A KR20200081432 A KR 20200081432A
Authority
KR
South Korea
Prior art keywords
topical
formulation
active substance
ethyl lactate
antifungal active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020207015246A
Other languages
English (en)
Korean (ko)
Inventor
노부유키 나토리
히로유키 다카베
다카시 이시마루
히로시 이세키
게이이치 가라사와
Original Assignee
가껭세이야꾸가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 가껭세이야꾸가부시기가이샤 filed Critical 가껭세이야꾸가부시기가이샤
Publication of KR20200081432A publication Critical patent/KR20200081432A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
KR1020207015246A 2017-10-30 2018-10-29 조백선 치료용 외부 제제 Ceased KR20200081432A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2017-209136 2017-10-30
JP2017209136 2017-10-30
PCT/JP2018/040047 WO2019088005A1 (ja) 2017-10-30 2018-10-29 爪白癬治療用の外用製剤

Publications (1)

Publication Number Publication Date
KR20200081432A true KR20200081432A (ko) 2020-07-07

Family

ID=66333195

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207015246A Ceased KR20200081432A (ko) 2017-10-30 2018-10-29 조백선 치료용 외부 제제

Country Status (14)

Country Link
US (1) US20210213002A1 (https=)
EP (1) EP3705136A4 (https=)
JP (2) JP6582158B1 (https=)
KR (1) KR20200081432A (https=)
CN (1) CN111295202B (https=)
AU (1) AU2018358372A1 (https=)
BR (1) BR112020008282A2 (https=)
CA (1) CA3081163A1 (https=)
IL (1) IL274100B2 (https=)
MX (1) MX2020004491A (https=)
RU (1) RU2020117569A (https=)
SG (1) SG11202003820VA (https=)
TW (1) TWI789448B (https=)
WO (1) WO2019088005A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102217617B1 (ko) * 2020-08-14 2021-02-19 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
WO2022035031A1 (ko) * 2020-08-14 2022-02-17 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021132348A1 (ja) * 2019-12-24 2021-07-01 科研製薬株式会社 エフィナコナゾールを含有する医薬
CN116887866A (zh) 2020-12-03 2023-10-13 巴特尔纪念研究院 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法
WO2022216977A1 (en) 2021-04-07 2022-10-13 Batelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
CN119654156A (zh) 2022-05-16 2025-03-18 玛路弘株式会社 白癣治疗用组合物
JPWO2025028651A1 (https=) * 2023-08-02 2025-02-06
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008019197A (ja) 2006-07-12 2008-01-31 Taisho Pharmaceut Co Ltd 抗真菌剤含有ｏ／ｗエマルション組成物
WO2009028495A1 (ja) 2007-08-27 2009-03-05 Nihon Nohyaku Co., Ltd. 真菌性皮膚炎用剤

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514385A (en) * 1981-10-05 1985-04-30 Alcon Laboratories, Inc. Anti-acne compositions
JPS58162514A (ja) * 1982-03-19 1983-09-27 Sumitomo Chem Co Ltd 外用ゲル製剤
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
CA2165802A1 (en) * 1993-09-29 1995-04-06 Eun Soo Lee Monoglyceride/lactate ester permeation enhancer for oxybutynin
EP1143950B1 (de) * 1998-09-10 2005-03-09 BioEqual AG Topisch anwendbare mittel gegen nagelpilzerkrankungen
US7384650B2 (en) * 1999-11-24 2008-06-10 Agile Therapeutics, Inc. Skin permeation enhancement composition for transdermal hormone delivery system
US8048919B2 (en) * 2004-06-28 2011-11-01 Archer Daniels Midland Company Use of ethyl lactate as an excipient for pharmaceutical compositions
NL2003711C2 (en) * 2009-10-27 2011-04-28 Shield Mark B V Aqueous composition for topical application, method of preparation, uses and device.
NL2003786C2 (en) * 2009-11-11 2010-07-30 Medner B V COMPOSITION FOR TOPICAL APPLICATION, USES THEREOF, APPLICATOR DEVICE AND KIT OF PARTS.
UA110816C2 (uk) * 2011-01-30 2016-02-25 Мейдзі Сейка Фарма Ко., Лтд. Місцевий протигрибковий засіб
KR20140088199A (ko) * 2011-11-04 2014-07-09 애자일 쎄라퓨틱스, 인크. 경피 전달 조성물 및 방법
US20150238606A1 (en) * 2012-09-14 2015-08-27 Pola Pharma Inc., Pharmaceutical composition containing luliconazole
EP2941128B1 (en) * 2012-12-20 2023-06-28 Rajiv Bhushan Antimicrobial compositions
TW201438742A (zh) * 2012-12-28 2014-10-16 大正製藥股份有限公司 皮膚適用製劑
CN103142458B (zh) * 2013-01-22 2015-09-09 莱普德制药有限公司 无成瘾性镇痛缓释递药系统的组方与制备方法
KR102612453B1 (ko) * 2013-11-22 2023-12-08 다우 파마슈티컬 사이언시즈, 인코포레이티드 항­감염 방법，조성물，및 장치
JP5623671B1 (ja) * 2014-07-23 2014-11-12 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
SG11201801856XA (en) 2015-09-18 2018-04-27 Kaken Pharmaceutical Co Ltd Biaryl derivative and medicine containing same
JP2017209136A (ja) 2016-05-23 2017-11-30 澁谷工業株式会社 電子線殺菌装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008019197A (ja) 2006-07-12 2008-01-31 Taisho Pharmaceut Co Ltd 抗真菌剤含有ｏ／ｗエマルション組成物
WO2009028495A1 (ja) 2007-08-27 2009-03-05 Nihon Nohyaku Co., Ltd. 真菌性皮膚炎用剤

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Astat (registered trade mark) Cream 1% Pharmaceutical Interview Forms, Maruho Co., Ltd. June, 2016 (revised 7th edition)
Clinical manual of Fungal nail disease (2005), NANKODO; 109-112
ZEFNART (registered trade mark) CREAM 2% Pharmaceutical Interview Forms, Torii Pharmaceutical Co., Ltd. January, 2010 (revised 7th edition)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102217617B1 (ko) * 2020-08-14 2021-02-19 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
WO2022035031A1 (ko) * 2020-08-14 2022-02-17 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물

Also Published As

Publication number Publication date
EP3705136A1 (en) 2020-09-09
RU2020117569A (ru) 2021-12-01
MX2020004491A (es) 2020-08-13
RU2020117569A3 (https=) 2021-12-01
JP6582158B1 (ja) 2019-09-25
IL274100A (en) 2020-06-30
CN111295202B (zh) 2022-07-08
BR112020008282A2 (pt) 2020-10-20
CN111295202A (zh) 2020-06-16
EP3705136A4 (en) 2021-08-18
US20210213002A1 (en) 2021-07-15
TWI789448B (zh) 2023-01-11
WO2019088005A1 (ja) 2019-05-09
JP2020011967A (ja) 2020-01-23
IL274100B2 (en) 2023-06-01
TW201922247A (zh) 2019-06-16
CA3081163A1 (en) 2019-05-09
AU2018358372A1 (en) 2020-05-28
SG11202003820VA (en) 2020-05-28
JPWO2019088005A1 (ja) 2019-11-14

Similar Documents

Publication Publication Date Title
KR20200081432A (ko) 조백선 치료용 외부 제제
KR101373955B1 (ko) 외용의 의약 조성물
US10881672B2 (en) Pharmaceutical tetracycline composition for dermatological use
US9968591B2 (en) Antifungal composition
US20100204293A1 (en) Pharmaceutical composition
WO2007102243A1 (ja) 外用の医薬組成物
US20090182004A1 (en) Imiquimod formulation
TW200810756A (en) Pharmaceuticals containing fluoroquinolones
JP2012526727A (ja) 皮膚および爪の真菌感染症の局所治療に適した組成物
EP2403476A1 (en) Method of dissolving antifungal agent, and compositions with a high concentration of antifungal agent, suitable for application to the nail
JP6956426B2 (ja) 水性外用剤
WO2004030665A1 (en) Transparent gel composition, for the administration of diclofenac sodium through the skin
JP6625208B2 (ja) 経皮製剤
JP2025510868A (ja) ミラベグロン製剤
HK40024555A (en) External preparation for treating trichophytosis unguium
HK40024555B (en) External preparation for treating trichophytosis unguium
WO2014017411A1 (ja) 爪白癬治療用外用剤
JP6084579B2 (ja) タクロリムスを含有する水中油型クリーム状組成物
JP2022067658A (ja) 皮膚外用クリーム剤
JP2002234837A (ja) トラニラスト含有水性外用製剤
KR20150131593A (ko) 항진균 의약 조성물

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20200527

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210903

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230725

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20231006

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230725

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I