KR20200055149A - 척추 유합 절차를 위한 조성물 및 방법 - Google Patents

척추 유합 절차를 위한 조성물 및 방법 Download PDF

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Publication number
KR20200055149A
KR20200055149A KR1020207013423A KR20207013423A KR20200055149A KR 20200055149 A KR20200055149 A KR 20200055149A KR 1020207013423 A KR1020207013423 A KR 1020207013423A KR 20207013423 A KR20207013423 A KR 20207013423A KR 20200055149 A KR20200055149 A KR 20200055149A
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South Korea
Prior art keywords
bone
pdgf
solution
tcp
support material
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English (en)
Korean (ko)
Inventor
사무엘 이. 린치
레오 비. 스넬
크리스토퍼 케이. 히
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바이오미메틱 세라퓨틱스, 엘엘씨
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Publication of KR20200055149A publication Critical patent/KR20200055149A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Composite Materials (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020207013423A 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법 Ceased KR20200055149A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42264910P 2010-12-13 2010-12-13
US61/422,649 2010-12-13
PCT/US2011/064698 WO2012082773A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020187031242A Division KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20200055149A true KR20200055149A (ko) 2020-05-20

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020207013423A Ceased KR20200055149A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020137015102A Ceased KR20140038348A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020137015102A Ceased KR20140038348A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Country Status (10)

Country Link
US (2) US20140308332A1 (cg-RX-API-DMAC7.html)
EP (1) EP2651319A4 (cg-RX-API-DMAC7.html)
JP (3) JP6116484B2 (cg-RX-API-DMAC7.html)
KR (3) KR20200055149A (cg-RX-API-DMAC7.html)
CN (2) CN103491888A (cg-RX-API-DMAC7.html)
AU (1) AU2011343995A1 (cg-RX-API-DMAC7.html)
BR (1) BR112013014686A2 (cg-RX-API-DMAC7.html)
CA (1) CA2819258C (cg-RX-API-DMAC7.html)
MX (1) MX362405B (cg-RX-API-DMAC7.html)
WO (1) WO2012082773A1 (cg-RX-API-DMAC7.html)

Cited By (1)

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DE102021112000A1 (de) 2020-05-08 2021-11-11 Mando Corporation Radarvorrichtung für fahrzeug, steuerverfahren der radarvorrichtung und radarsystem für fahrzeug

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EP2654796A1 (en) 2010-12-21 2013-10-30 Koninklijke Philips N.V. Agents for clearing biomolecules from circulation
WO2016043955A1 (en) * 2014-08-28 2016-03-24 Bioventus, Llc Improved osteoinductive substrates and methods of making the same
CN107106492B (zh) 2014-10-14 2022-07-05 塞缪尔·林奇 用于治疗伤口的组合物
JP2018500135A (ja) 2014-12-29 2018-01-11 バイオヴェンタス・エルエルシー 骨修復における骨誘導分子の改善された送達システム及び方法
WO2017019959A1 (en) * 2015-07-30 2017-02-02 Clarion Research Group Formulations and methods for recovery from spinal surgery
EP3368094B1 (en) 2015-10-30 2021-03-10 Bioventus LLC Matrix for enhanced delivery of osteoinductive molecules in bone repair
US12318475B2 (en) 2016-03-14 2025-06-03 The University Of Chicago Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles
JP2019518550A (ja) 2016-06-10 2019-07-04 バイオヴェンタス・エルエルシー 多孔質金属構造物でのタンパク質送達
WO2019014576A1 (en) * 2017-07-14 2019-01-17 The University Of Chicago LYOPHILIZED FORMULATIONS COMPRISING NANOPARTICLES AND METHODS OF LYOPHILIZATION
JP2022525168A (ja) * 2019-03-14 2022-05-11 バイオミメティック セラピューティクス，リミテッド ライアビリティ カンパニー 骨癒合を増強するための血小板由来増殖因子製剤
EP3795185A1 (en) * 2019-09-23 2021-03-24 Kuros Biosurgery AG Bone graft material for use in a spinal fusion method
CN111481741A (zh) * 2020-04-15 2020-08-04 花沐医疗科技(上海)有限公司 复合可吸收自锁定颈椎融合器及其制备方法
WO2025042830A1 (en) 2023-08-18 2025-02-27 Biomimetic Therapeutics, Llc Platelet-derived growth factor bone graft putty formulation

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Publication number Priority date Publication date Assignee Title
DE102021112000A1 (de) 2020-05-08 2021-11-11 Mando Corporation Radarvorrichtung für fahrzeug, steuerverfahren der radarvorrichtung und radarsystem für fahrzeug

Also Published As

Publication number Publication date
MX362405B (es) 2019-01-15
AU2011343995A1 (en) 2013-06-20
JP2018161541A (ja) 2018-10-18
EP2651319A1 (en) 2013-10-23
CA2819258C (en) 2020-03-10
JP6116484B2 (ja) 2017-04-19
JP2017018710A (ja) 2017-01-26
MX2013006697A (es) 2013-10-30
KR20140038348A (ko) 2014-03-28
JP2013545584A (ja) 2013-12-26
US20140308332A1 (en) 2014-10-16
CA2819258A1 (en) 2012-06-21
CN108498873A (zh) 2018-09-07
KR20180121674A (ko) 2018-11-07
EP2651319A4 (en) 2016-08-17
CN103491888A (zh) 2014-01-01
WO2012082773A1 (en) 2012-06-21
US20190365946A1 (en) 2019-12-05
BR112013014686A2 (pt) 2016-10-04

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