KR20200032738A - 가변 및 불변 도메인 사이의 엘보우 영역에 기능성 도메인을 갖는 항체 - Google Patents
가변 및 불변 도메인 사이의 엘보우 영역에 기능성 도메인을 갖는 항체 Download PDFInfo
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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| BR112020018918A2 (pt) | 2018-03-22 | 2021-01-05 | Surface Oncology, Inc. | Anticorpos anti-il-27 e usos dos mesmos |
| AU2019266042B2 (en) * | 2018-05-10 | 2025-08-07 | Mirabiologics Inc. | Artificial protein containing an antibody antigen-binding region, fused with bioactive peptides |
| MX2020012895A (es) | 2018-05-30 | 2021-05-27 | Inst Res Biomedicine | Modificacion de linfocitos b al utilizar citidina desaminasa inducida por activacion endogena. |
| EP3927728A2 (en) | 2019-02-21 | 2021-12-29 | Xencor, Inc. | Untargeted and targeted il-10 fc-fusion proteins |
| EP4100434A1 (en) | 2020-02-03 | 2022-12-14 | VIR Biotechnology, Inc. | Antibodies against sars-cov-2 and methods of using the same |
| TWI859420B (zh) | 2020-02-26 | 2024-10-21 | 美商維爾生物科技股份有限公司 | 抗sars-cov-2抗體及使用其之方法 |
| WO2021203053A1 (en) | 2020-04-03 | 2021-10-07 | Vir Biotechnology, Inc. | Immunotherapy targeting a conserved region in sars coronaviruses |
| EP4135846A1 (en) | 2020-04-14 | 2023-02-22 | VIR Biotechnology, Inc. | Antibodies against sars-cov-2 and methods of using the same |
| JP2023525039A (ja) | 2020-05-08 | 2023-06-14 | ヴィア・バイオテクノロジー・インコーポレイテッド | Ｓａｒｓ－ｃｏｖ－２に対する抗体 |
| WO2021247925A1 (en) | 2020-06-03 | 2021-12-09 | Vir Biotechnology, Inc. | Structure-guided immunotherapy against sars-cov-2 |
| CA3180477A1 (en) | 2020-06-12 | 2021-12-16 | Elizabeth Alexander | Antibody therapies for sars-cov-2 infection |
| EP4217385A2 (en) | 2020-09-28 | 2023-08-02 | VIR Biotechnology, Inc. | Antibodies against sars-cov-2 |
| CN112225807B (zh) * | 2020-10-30 | 2021-09-07 | 上海洛启生物医药技术有限公司 | 抗il5纳米抗体及其应用 |
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| KR20230135569A (ko) | 2020-11-23 | 2023-09-25 | 비르 바이오테크놀로지, 인코포레이티드 | 인플루엔자 a 바이러스에 대한 항체 |
| WO2022109309A1 (en) | 2020-11-23 | 2022-05-27 | Vir Biotechnology, Inc. | Broadly neutralizing antibodies against influenza neuraminidase |
| WO2022115486A1 (en) | 2020-11-25 | 2022-06-02 | Vir Biotechnology, Inc. | Antibodies that bind to multiple betacoronaviruses |
| EP4263600A1 (en) | 2020-12-18 | 2023-10-25 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| EP4271715A4 (en) * | 2020-12-30 | 2024-11-20 | Wuxi Biologics Ireland Limited | MULTI-SPECIFIC ANTIGEN-BINDING PROTEINS |
| CN112877394A (zh) * | 2021-01-27 | 2021-06-01 | 南京大学 | B7-h4+单核细胞型mdsc在制备ins激素治疗疗效预测试剂中的应用 |
| WO2022204202A1 (en) | 2021-03-23 | 2022-09-29 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
| WO2022236142A2 (en) * | 2021-05-07 | 2022-11-10 | Senti Biosciences, Inc. | Chimeric receptors and methods of use thereof |
| AU2022280767A1 (en) | 2021-05-24 | 2024-01-18 | Humabs Biomed Sa | Engineered polypeptides |
| WO2023034866A1 (en) | 2021-09-01 | 2023-03-09 | Vir Biotechnology, Inc. | Antibody therapies for sars-cov-2 infection in pediatric subjects |
| WO2023034871A1 (en) | 2021-09-01 | 2023-03-09 | Vir Biotechnology, Inc. | High concentration antibody therapies for sars-cov-2 infection |
| CN114934065A (zh) * | 2021-11-25 | 2022-08-23 | 浙江理工大学绍兴生物医药研究院有限公司 | 携带免疫检查点分子tim-3抗体基因的溶瘤腺病毒构建方法和应用 |
| EP4444758A2 (en) | 2021-12-10 | 2024-10-16 | Omeros Corporation | Therapeutic antibodies that bind to the serine protease domain of masp-2 and uses thereof |
| US20230416406A1 (en) | 2022-03-10 | 2023-12-28 | Omeros Corporation | Masp-2 and masp-3 inhibitors, and related compositions and methods, for treatment of sickle cell disease |
| WO2023201256A1 (en) | 2022-04-12 | 2023-10-19 | Vir Biotechnology, Inc. | High dose antibody therapies for sars-cov-2 infection |
| WO2023230448A1 (en) | 2022-05-23 | 2023-11-30 | Vir Biotechnology, Inc. | Combination immunotherapy for influenza |
| JP2025522295A (ja) | 2022-05-23 | 2025-07-15 | ヒューマブス・バイオメッド・ソシエテ・アノニム | インフルエンザノイラミニダーゼに対する広域中和抗体 |
| WO2023245078A1 (en) | 2022-06-15 | 2023-12-21 | Humabs Biomed Sa | Anti-parvovirus antibodies and uses thereof |
| WO2024006472A1 (en) | 2022-06-30 | 2024-01-04 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
| EP4562034A1 (en) | 2022-07-27 | 2025-06-04 | Humabs Biomed SA | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
| WO2024112818A1 (en) | 2022-11-22 | 2024-05-30 | Humabs Biomed Sa | Engineered anti-sars-cov-2 antibodies and uses thereof |
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| WO2025010424A1 (en) | 2023-07-06 | 2025-01-09 | Vir Biotechnology, Inc. | Antibodies against staphylococcus antigens and methods of using the same |
| WO2025015321A1 (en) | 2023-07-13 | 2025-01-16 | Vir Biotechnology, Inc. | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
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| AU2001270609A1 (en) * | 2000-06-30 | 2002-01-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Heterodimeric fusion proteins |
| AU2004215125B2 (en) | 2003-02-26 | 2011-01-06 | Institute For Research In Biomedicine | Monoclonal antibody production by EBV transformation of B cells |
| WO2005000898A2 (en) | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
| BRPI0811857A2 (pt) | 2007-05-14 | 2014-10-21 | Biogen Idec Inc | Regiões fc (scfc) de cadeia simples, polipeptídeos de aglutinação que as compreendem e métodos relacionados. |
| EP2626371A1 (en) * | 2007-07-31 | 2013-08-14 | MedImmune, LLC | Multispecific epitope binding proteins and uses thereof |
| ES2525346T3 (es) | 2008-10-22 | 2014-12-22 | Institute For Research In Biomedicine | Métodos para producir anticuerpos a partir de células plasmáticas |
| WO2012088290A2 (en) * | 2010-12-22 | 2012-06-28 | Abbott Laboratories | Tri-variable domain binding proteins and uses thereof |
| US20140235476A1 (en) * | 2012-12-28 | 2014-08-21 | Abbvie, Inc. | Multivalent binding protein compositions and methods for identifying variants of same |
| HK1216894A1 (zh) * | 2012-12-28 | 2016-12-09 | Abbvie Inc. | 多價結合蛋白組合物 |
| US9814784B2 (en) | 2013-01-03 | 2017-11-14 | Celltrion, Inc. | Antibody-linker-drug conjugate, preparation method therefor, and anticancer drug composition containing same |
| US10526404B2 (en) * | 2015-04-29 | 2020-01-07 | Institute For Research In Biomedicine | Multispecific anti GM-CSF antibodies |
| AU2016277887B2 (en) * | 2015-06-18 | 2022-06-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunoglobulin single variable domain antibody against RSV prefusion F protein |
| EA039366B1 (ru) * | 2015-06-24 | 2022-01-19 | Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. | Антитело к рецептору трансферрина человека, проникающее через гематоэнцефалический барьер |
| EP3313871A1 (en) | 2015-06-26 | 2018-05-02 | Institute for Research in Biomedicine | Proteins comprising a mutated lair-1 fragment and uses thereof |
| KR20180085800A (ko) * | 2015-12-07 | 2018-07-27 | 젠코어 인코포레이티드 | Cd3 및 psma에 결합하는 이종이합체성 항체 |
| AU2019266042B2 (en) * | 2018-05-10 | 2025-08-07 | Mirabiologics Inc. | Artificial protein containing an antibody antigen-binding region, fused with bioactive peptides |
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