KR20200030126A - Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 - Google Patents

Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 Download PDF

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KR20200030126A
KR20200030126A KR1020207007076A KR20207007076A KR20200030126A KR 20200030126 A KR20200030126 A KR 20200030126A KR 1020207007076 A KR1020207007076 A KR 1020207007076A KR 20207007076 A KR20207007076 A KR 20207007076A KR 20200030126 A KR20200030126 A KR 20200030126A
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compound
disease
compounds
ssao
vap
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Korean (ko)
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맨달 데오드할
알리손 도로시 핀들레이
조나단 스튜어트 풋
울프강 자로리멕
이안 알렉산더 맥도날드
앨런 로버트손
크레이그 이반 터너
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베링거 인겔하임 인터내셔날 게엠베하
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    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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    • C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

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KR1020207007076A 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 Ceased KR20200030126A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261641814P 2012-05-02 2012-05-02
US61/641,814 2012-05-02
PCT/AU2013/000356 WO2013163675A1 (en) 2012-05-02 2013-04-05 Substituted 3-haloallylamine inhibitors of ssao and uses thereof

Related Parent Applications (1)

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KR1020147032073A Division KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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KR20200030126A true KR20200030126A (ko) 2020-03-19

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KR1020207007076A Ceased KR20200030126A (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들
KR1020147032073A Active KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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KR1020147032073A Active KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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US (4) US9302986B2 (cg-RX-API-DMAC7.html)
EP (2) EP3438087A1 (cg-RX-API-DMAC7.html)
JP (3) JP6182595B2 (cg-RX-API-DMAC7.html)
KR (2) KR20200030126A (cg-RX-API-DMAC7.html)
CN (2) CN107266332B (cg-RX-API-DMAC7.html)
AU (2) AU2013255103B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014027406B1 (cg-RX-API-DMAC7.html)
CA (2) CA2871793C (cg-RX-API-DMAC7.html)
CY (1) CY1120334T1 (cg-RX-API-DMAC7.html)
DK (1) DK2844637T5 (cg-RX-API-DMAC7.html)
ES (1) ES2668300T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20180953T1 (cg-RX-API-DMAC7.html)
HU (1) HUE038437T2 (cg-RX-API-DMAC7.html)
LT (1) LT2844637T (cg-RX-API-DMAC7.html)
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MX (2) MX377635B (cg-RX-API-DMAC7.html)
NO (1) NO2842608T3 (cg-RX-API-DMAC7.html)
PL (1) PL2844637T3 (cg-RX-API-DMAC7.html)
PT (1) PT2844637T (cg-RX-API-DMAC7.html)
RS (1) RS57086B1 (cg-RX-API-DMAC7.html)
SG (2) SG10201707020TA (cg-RX-API-DMAC7.html)
SI (1) SI2844637T1 (cg-RX-API-DMAC7.html)
TR (1) TR201807453T4 (cg-RX-API-DMAC7.html)
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MX377635B (es) * 2012-05-02 2025-03-11 Boehringer Ingelheim Int Inhibidores de 3-haloalilamina sustituidos de ssao y uso de los mismos
GB201304526D0 (en) 2013-03-13 2013-04-24 Proximagen Ltd New compounds
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
JP2018076236A (ja) * 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
AU2016366635A1 (en) 2015-12-07 2018-06-21 Benevolentai Cambridge Limited VAP-1 inhibitors for treating pain
SG11201806700RA (en) * 2016-02-12 2018-09-27 Pharmaxis Ltd Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof
WO2018027892A1 (en) * 2016-08-12 2018-02-15 Eli Lilly And Company Amino pyrimidine ssao inhibitors
MX2019004549A (es) * 2016-10-19 2019-06-12 Boehringer Ingelheim Int Combinaciones que comprenden un inhibidor ssao/vap-1 y un inhibidor sglt2 y usos de los mismos.
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
CN108341752B (zh) * 2017-01-21 2022-12-23 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
WO2018148856A1 (en) 2017-02-14 2018-08-23 Eli Lilly And Company Diazaspirodecanyl-pyrimidine compounds useful as ssao inhibitors
JP7145872B2 (ja) 2017-03-01 2022-10-03 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング α－ハロ－アクリル酸誘導体の遷移金属触媒によるプロト脱炭酸
US20200069648A1 (en) * 2017-03-02 2020-03-05 Pharmaxis Ltd. Haloallylamine pyrazole derivative inhibitors of lysyl oxidases and uses thereof
US20200087248A1 (en) * 2017-04-28 2020-03-19 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Fluoroallylamine Derivative And Use Thereof
CN110662534A (zh) 2017-05-31 2020-01-07 勃林格殷格翰国际有限公司 包含(e)-4-(2-(氨基甲基)-3-氟烯丙基氧基)-n-叔丁基苯甲酰胺的药物组合物和药物剂型，其制备方法、治疗方法及用途
GB201709136D0 (en) * 2017-06-08 2017-07-26 Proximagen Ltd New therapeutic uses of enzyme inhibitors
CN110719902B (zh) * 2017-06-20 2022-08-12 山东丹红制药有限公司 Ssao抑制剂
CN109251166B (zh) * 2017-07-13 2021-11-05 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
WO2019024924A1 (zh) * 2017-08-04 2019-02-07 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
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