KR20180086725A - Toothpaste composition comprising rice bran fine particles as a natural abrasive and preparing method thereof - Google Patents

Abstract

The present invention relates to a toothpaste composition containing rice bran as a natural abrasive agent and a preparation method thereof. According to the present invention, the toothpaste composition contains rice bran particulates as a natural abrasive agent, wherein the particulates have an average particle diameter of 5-15 μm, wherein at least 40 vol% of the particulates have a particle diameter of 10 μm or less and at least 90 vol% of the particulates have a particle diameter of 25 μm or less. The toothpaste composition, due to containing the rice bran particulates serving as a natural abrasive agent and having uniform particle distribution and hardness, exhibits excellent dental plaque and tartar removal efficiency; exhibits whitening effects of rice bran and contains substances good for the gum, such as vitamin B_1, B_2 and E, and the like, and thus has teeth whitening effect and benefits on gum health; is capable of eliminating bad breath effectively; due to not containing various harmful substances, minimizes concerns for adverse side effects, and thus can be safely used by users; and can produce high value-added products by recycling rice bran which is an agricultural by-product typically discarded as waste.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dentifrice composition containing a rice bran as a natural abrasive and a method of manufacturing the same. BACKGROUND ART < RTI ID = 0.0 >

The present invention relates to a dentifrice composition containing a rice bran as a natural abrasive and a preparation method thereof, and more particularly, to a dentifrice composition containing a natural abrasive and a paraben which is a preservative that does not contain triclosan and fluorine, (SLS), which is a chemical surfactant, is replaced by a natural surfactant and a foaming agent. In addition, as a natural abrasive, it is used as a natural abrasive, which contains whitening and gum ingredients and has a uniform particle distribution and hardness. The present invention relates to a dentifrice composition containing powdered rice bran (rice bran) as a natural abrasive and a process for producing the dentifrice composition.

Rice ( Oryza sativa ) is one of the most important grains in the world, with about 600 million tons of rice being produced annually worldwide. About 95% of the rice produced is used as a stock of Asians over half the world's population have.

On the other hand, rice bran (rice bran) is a major by-product of rice cultivation process of making brown rice, which is about 8% of the rice, which is crushed mixture of peel, seed coat, Lt; / RTI >

It is known that rice bran is rich in various minerals and nutrients. It is remarkably low in allergen inducing ingredients compared to other grains and foods, and is known to have excellent whitening effect by abundant niacin (vitamin B ₃ ), pantothenic acid and choline. Vitamin B ₁ , B ₂ , and E as well as pythonic acid, which has the body's waste and detoxifying action, and pantothenic acid to prevent allergy. In recent years, it has been known to contain antioxidants, Have been reported to have various healthful effects including anti-hyperlipidemia. In addition, rich in vitamin A and various minerals in the rice gangs, it promotes metabolism and inhibits disease development, which helps to strengthen immunity.

However, despite the potential use of rice bran, only 20-30% of the produced rice bran is used for the production of rice bran oil. Most of the rice bran is discarded or partially used as livestock feed or fertilizer. Recently, moisturizing or whitening cosmetics There have been only a few attempts to use health functional foods or medicines as raw materials.

On the other hand, toothpastes consist of abrasives, surfactants, binders, wetting agents, antimicrobial preservatives and other auxiliary ingredients.

Parabens, triclosan, and synthetic surfactants have been widely used as antimicrobial preservatives in conventional toothpastes. Saccharin has been widely used as an artificial sweetener, and fluorine compounds as a dental caries prevention agent have also been widely used.

However, the compound group of parahydroxybenzoic acid ester used as the common name of "paraben" has the effect of inhibiting the growth of bacteria, yeast and fungi at a concentration which is slightly different depending on the compound, Recently, it has been reported that it is a hormone disturbance substance causing skin diseases, central nervous system paralysis, cancer, etc. Especially, paraoxybenzoic acid ester (methylparaben) is considered to cause gene mutation upon ingestion . In addition, parabens are accumulated in the body without being released from the body when they are absorbed into the body, so that there is a concern about accumulation of parabens through the oral mucosa.

In addition, triclosan is used in toothpaste to prevent periodontal disease and to remove bad breath because it has sterility and saliva. However, it increases the risk of male infertility and breast cancer in women, causes heart contraction and deterioration of sensory gland function, . ≪ / RTI >

Synthetic surfactant, sodium laureth sulfate (SLS), is known to cause irritation in the mouth, causing mucosal dislocation, ulceration, stomatitis, gum ache, and atopy.

Hydrofluoric acid and salts thereof are toxic substances, but fluorine ions form fluorine apatite ([Ca ₃ (PO ₄ ) ₂ ] _3. CaF ₂ ) which is harder than dentin and does not contain hydroxyl groups and does not react with acid, , It may be contained in an amount of less than 1 ppm. However, when the fluorine ion reaches about 2 to 3 ppm, it is recognized as a harmful raw material as side effects such as causing spots are revealed.

Saccharin, which is also used as a sweetener in some toothpastes, is known to have digestive and kidney disorders and is reported to be a suspected carcinogen.

Therefore, the need for development of a toothpaste that can be safely used by a user has been demanded in the art for a long time because the various harmful components as described above are not included and the concern about side effects is minimized.

Korean Patent Laid-Open Publication No. 10-2011-0095804 (published on Aug. 25, 2011) discloses a method in which the herb such as soybean, brown rice, rice bran and the like is fed into an extractor at a ratio of 1: 1, The enzymatic dentifrice was prepared by adding purified enzyme concentrate to a toothpaste base. The enzyme dentifrice added to the toothpaste base was briefly described in Example 7, but the dentifrice used was an enzyme fermentation broth of an extract containing rice bran. Rice bran is not used as a natural abrasive at all.

There are some prior arts related to health functional foods including a moisturizing and whitening cosmetic composition and rice bran, but since they are not all related to dentifrice compositions, they are not directly related to the present invention.

Korean Unexamined Patent Application Publication No. 10-2011-0095804 (published on August 25, 2011)

Therefore, a first object of the present invention is to provide a dentifrice composition having excellent teeth and tartar removal efficiency by using a natural abrasive having a uniform particle distribution and hardness in combination.

The second object of the present invention is to provide a dentifrice composition having excellent halitosis Removal comprises a natural slurry containing the whitening efficacy and gums useful components of vitamin B _1, B _2, E and so on.

A third object of the present invention is to provide a dentifrice composition which can be safely used by a user by minimizing the risk of side effects because various harmful components are not included.

A fourth object of the present invention is to provide a dentifrice composition which is capable of high value-added by recycling agricultural by-products that are dumped into waste.

A fifth object of the present invention is to provide a method for producing an effective dentifrice composition according to the above objects.

In order to achieve the first to fourth objects of the present invention, it is preferable that the average particle size is 5 to 15 μm, the ratio of 10 μm or less is at least 40% by volume, There is provided a dentifrice composition containing, as an abrasive, rice bran fine particles of 90 vol.% As a natural abrasive.

The dentifrice composition containing the above-mentioned rice bran as a natural abrasive agent may contain 3 to 12% by weight of the rice bran micropowder powder based on the total weight of the composition.

The dentifrice composition containing the microcrystalline wax as a natural abrasive comprises 20 to 60% by weight of the abrasive containing 3 to 12% by weight of the fine micropowder powder, 20 to 40% by weight of the wetting agent, 0.1 to 10% 0.1 to 5 wt% of a sweetener, 0.1 to 3 wt% of a natural surfactant, 0.1 to 1 wt% of a natural flavor, 0.05 to 5 wt% of an anti-fouling agent as an efficacy enhancer, 0.1 to 5 wt% of a natural preservative, Lt; / RTI >

In order to achieve the fifth object of the present invention, there is provided a method for manufacturing a steel sheet, comprising the steps of (A) wet-milling a steel sheet, drying and pulverizing the steel sheet, At least 40% by volume, and 3 to 12% by weight of rice bran fine particles with a proportion of at least 90% by volume in a proportion of less than 25 占 퐉, precipitated calcium carbonate, calcium hydrogenphosphate hydrate, aluminum hydroxide, precipitated silica, To 8 to 57% by weight of at least one abrasive agent selected from the group consisting of the following: a) adding 20 to 40% by weight of a wetting agent to the abrasive mixture; (B) homogeneously mixing 0.1 to 5% by weight of a sweetener, 0.1 to 3% by weight of a natural surfactant as a foaming agent, and 0.05 to 5% by weight of an anti-fouling agent as an effect enhancing agent, in a wetted abrasive mixture; (C) adding purified water and 0.1 to 10% by weight of a binder to the mixed mixture and stirring to give a viscosity; There is provided a method for producing a dentifrice composition containing, as a natural abrasive, a raw corundum composed of (D) mixing 0.1 to 1% by weight of a natural flavor and 0.1 to 5% by weight of a natural preservative in a viscous mixture.

Herein, the above-mentioned rice bran fine powder to be subjected to wet grinding and drying and then shredded may be further subjected to a shredding treatment using a vacuum rotary cyclone mill.

The toothpaste composition according to the present invention, which contains the rice bran as a natural abrasive, has excellent particle and tartar removal efficiency because of the uniform particle distribution and hardness of the rice bran powder as an abrasive. The whitening effect of rice bran and the vitamin B ₁ , B ₂ , and E, it is useful for tooth whitening and gum health, and also has excellent bad breath removing ability. In particular, since it does not contain various harmful components, the concern about side effects is minimized, Which is a byproduct of agriculture, which can be recycled as a byproduct.

Fig. 1 is a particle size analysis data chart of the fine pulverized rice bran in the ground state of Comparative Example 1. Fig.
Fig. 2 is a particle size analysis data chart of the rice bran micropowder powder of Example 1. Fig.
Fig. 3 is a particle size analysis data chart of the rice germ powder of Examples 2 and 3.
Fig. 4 is a comparative analysis chart of the particle size distribution of Comparative Example 1 and Examples 1 to 3. Fig.
FIGS. 5A and 5B are graphs showing mean values of halitosis before and after toothpaste composition containing the rice flour fine powder of Example 4. FIG.
FIGS. 6A and 6B are graphs showing mean values of halitosis before and after toothpaste composition containing the microgranular fine powder of Example 5. FIG.
FIGS. 7A and 7B are graphs showing average values of halitosis before and after toothpaste composition containing the microgranular fine powder of Example 6, respectively. FIG.
8A and 8B are graphs showing the mean value of halitosis before and after toothpaste treatment using a dentifrice composition containing fine pulverized rice bran of Comparative Example 1, respectively.
FIGS. 9A and 9B are graphs showing mean values of halitosis before and after toothbrushing using a toothpaste composition containing no rice bran, respectively.
FIG. 10 is a block diagram of the manufacturing process of a dentifrice composition containing the micropowder of the present invention as a natural abrasive.

Hereinafter, the present invention will be described in detail.

The dentifrice composition containing the microcrystalline cellulose according to the present invention as a natural abrasive has an average particle diameter of 5 to 15 탆, preferably 7 to 12 탆, and a ratio of the particle diameter of 10 탆 or less is 40 vol% or more, preferably 50 to 80 By volume and a ratio of not more than 25 mu m of not less than 90% by volume, preferably 97 to 99.9% by volume, as an abrasive.

The dentifrice composition according to the present invention may contain 3 to 12% by weight, based on the total weight of the composition, of the micropowder fine powder as the natural abrasive.

If the average particle size of the rice briquette fine powder is less than 5 탆, the polishing effect may be lowered and the milling takes a lot of time and effort, which is not economical. Conversely, if the average grain size exceeds 15 탆, the polishing effect becomes too large, There is a possibility of damaging the quality.

Since the rice bran is relatively higher in oil and moisture content than other grains, it is possible to carry out a drying process to lower the moisture to 10% or less, but this is optional in the present invention.

The raw rice bran produced by the rolling is in the range of 0.1-500 탆 in particle diameter and the average particle diameter is about 72.36 탆, so that it should be ground to 20 탆 or less which is the usual particle diameter of the toothpaste abrasive.

In the case of the micro-pulverization treatment of rice bran, dry milling, in which coagulation due to oil in the rice bran occurs, may be undesirable, and it is preferable to use a micro-particle pulverizing method by wet milling. After pulverizing, it is naturally dried at room temperature or hot-air dried to remove volatile components and moisture, and then the agglomerated micropowder powder is pulverized, and if necessary, it can be pulverized again under reduced pressure vacuum or under normal pressure.

The dentifrice composition of the present invention containing the raw rice bran as a natural abrasive may contain precipitated calcium carbonate, calcium hydrogenphosphate hydrate, aluminum hydroxide, precipitated silica, hydrated silicic acid, magnesium carbonate, or any mixture thereof Of abrasive.

Since the conventional abrasive has a problem in that the hardness is not constant because the particles are uneven and the abrasive effect is liable to be deteriorated. Therefore, the untreated dentifrice composition according to the present invention can reduce the abrasive content of the known abrasive, It is used as a natural abrasive. As it is known, rice bran is already proven to be whitening effect, has a good detoxifying effect and is rich in vitamin B group which is useful ingredient in gums.

Using rice bran as a natural abrasive, it can safely and effectively remove plaque (chunks of fine food waste and bacteria) and calcified tartar.

If the amount is less than 3% by weight, the sufficient effect of addition may not be obtained. Conversely, when the amount is more than 12% by weight, there is a fear that it is not economical. Is contained in an amount of 8 to 57% by weight based on the total weight.

Therefore, the total amount of the abrasive containing the rice briquette fine powder is 20 to 60% by weight based on the total weight of the toothpaste composition.

The dentifrice composition according to the present invention comprises 20 to 60% by weight of an abrasive containing 3 to 12% by weight of the rice flour fine powder, 20 to 40% by weight of a wetting agent, 0.1 to 10% 0.1 to 5 wt% of a sweetener, 0.1 to 3 wt% of a natural surfactant, 0.1 to 1 wt% of a natural flavor, 0.05 to 5 wt% of an anti-fouling agent as an efficacy enhancer, 0.1 to 5 wt% of a natural preservative, , And the remainder is composed of water.

The dentifrice composition containing the rice bran as a natural abrasive according to the present invention does not contain parabens and triclosan, which are antioxidants that may disturb the secretion of hormones and cause cancer, and the mineral oil is replaced with natural essential oil, Natural surfactants and natural foaming agents are used instead of chemical surfactants such as lauryl sulfate (SLS), and artificial coloring matters, fluorine, and artificial fragrances are not used, and these are shown in Table 1 below.

ingredient Side Effect Alternative components of the present invention efficacy Artificial coloring matter Allergen induction No additives - Chemical preservative Hormonal abnormality Propolis Natural antibacterial agent Mineral oil Induce skin disease Natural Essential Oils Vitamin content
Natural spices
Enhance toothpaste efficacy SLS
(Chemical surfactant) Skin irritation Cocoyl glutamine
salt Natural surfactant Artificial fragrance Allergen induction Natural Essential Oils - Fluorine Gastrointestinal disorders,
Human accumulation No additives -

As the wetting agent used in the dentifrice composition containing the rice bran as a natural abrasive according to the present invention, glycerin, D-sorbitol liquid, polyethylene glycol and propylene glycol may be used alone or in combination. The amount of the wetting agent used is 20 to 40 By weight.

Preferred humectants in the present invention are aqueous solutions of glycerine and D-sorbitol, wherein D-sorbitol is also referred to as glucitol, and hygroscopic alcohols produced by reducing glucose are used as sweeteners in food additives as sweeteners The sweetness is about 50% of the sugar. It is used as the preparation of ascorbic acid, delayed solidification of the sugar in the preparation of candy, moisturizer, sugar substitute, etc. It is a low moisture and moisturizing agent excellent in heat resistance and refreshing feeling. Of wetting agent.

Carboxymethylcellulose sodium (CMC), carrageenan, xanthan gum, gum arabic, or any mixture thereof may be used as a binder or a binder used in a dentifrice composition containing a cornstarch according to the present invention as a natural abrasive. And more specifically 0.1 to 10% by weight based on the total weight of the dentifrice composition.

The carboxymethylcellulose sodium (CMC) as a carboxymethylcellulose sodium (CMC) is a white solid which is prepared by reacting alkali cellulose with chloroacetate. It is preferable that the microcrystalline dentifrice composition according to the present invention is formulated in a uniform and stable form .

In the present invention, parabens as a binder or preservative are not included at all.

The sweetener to be used in the dentifrice composition containing the rice bran as a natural abrasive according to the present invention is not particularly limited, but there is no particular limitation, but the xylitol, steviol glycoside extracted from stevia leaves, sage extract containing a large amount of vitamin C, erythritol, Can be used. In particular, xylitol and steviol glycosides can be used together.

The addition amount thereof is not limited in the present invention, but may be added in the range of 0.1 to 5% by weight.

In the present invention, saccharin sodium as a sweetening agent and aspartame which is a synthetic sweetening agent are not used at all.

As the natural surfactant used in the dentifrice composition containing the rice bran as a natural abrasive according to the present invention, sodium cocoyl glutamate and / or apple wash obtained from palm tree may be used. In particular, sodium cocoyl glutamate stimulates the skin Is a natural surfactant with a mild ingredient that does not give a soft feel, smooth and bubbles, and has a high density, indicating excellent feeling.

The amount thereof may be used in an appropriate amount, specifically 0.1 to 3% by weight.

Natural essential oils as a natural or natural flavoring agent used in a dentifrice composition containing a rice bran as a natural abrasive according to the present invention are added in place of a mineral oil and there are no particular limitations on its kind, but lemon grass oil, basil oil, L- Menthol-rich peppermint, peppermint oil, or mixtures thereof. These may be added in an appropriate amount, but may be added in an amount of 0.1 to 1% by weight.

Since the rice bran itself in the dentifrice composition containing the rice bran according to the present invention as a natural abrasive is close to odorless, natural essential oil which does not irritate the gum to impart flavor is added to improve flavor and to formulate a gum therapy effect The clove is a refreshing and sweet fragrance. It has strong antiseptic and disinfecting power. Clove oil extracted from cloves alleviates toothache and gum ache, as well as helps to prevent bad breath. Peppermint contains a lot of menthol to relieve pain There is also an analgesic effect, and Basil has the effect of eliminating bad breath through a unique mint flavor of Basil.

As the anti-aging agent as an efficacy enhancer used in a dentifrice composition containing a rice bran as a natural abrasive according to the present invention, aminocaproic acid, allantoin chlorohydroxyaluminum, or a mixture thereof is used, and allantoin chlorohydroxy aluminum is used In the dentifrice composition containing natural cornstarch according to the present invention as a natural ingredient, it protects the oral mucous membrane with an antifogging agent to prevent gum inflammation, prevent swelling and flare accompanying with gingivitis and periodontal disease, and relieve pain of gum inflammation It is used as a safe and effective enhancer. It has no toxicity and low irritation. It shows wound healing, soothing and cleansing effect even at low concentration. It shows effects such as tooth decay prevention, tooth whitening, prevention of dental deposition, Capronic acid is also an anti-aging agent and has excellent anti-hemorrhage, anti-inflammatory effect And has a hemostatic effect to prevent gum bleeding.

0.05 to 5% by weight, based on the weight of the entire composition, is used. Specifically, 0.1% by weight of allantoin chlorohydroxyaluminum and 0.05% by weight of aminocaproic acid can be used.

The natural preservative used in the dentifrice composition containing the rice bran as a natural abrasive according to the present invention may be propolis extract, grapefruit seed extract (GSE), or a mixture thereof. Preferably, the propolis extract is a propolis extract, And 0.1 to 5% by weight based on the weight.

Propolis is a natural antimicrobial used in place of the chemical preservative parabens. It contains 20 to 30 kinds of flavonoids. It is rich in organic substances and minerals (minerals). Minerals, vitamins, amino acids, fats, organic acids and flavonoids It plays an important role in metabolism, and terpenes and the like have an anticancer effect, so that it is possible to obtain an effect of removing staphylococci having a strong resistance against bacteria, viruses and the like.

The above grapefruit seed extract may be classified as a natural sweetener or a natural flavoring agent.

In addition, calcium hydrogen phosphate hydrate is used as an abrasive for toothpaste, but it may be classified as an efficacy enhancer to prevent gum disease, to remove bad breath, to keep oral hygiene healthy, and to alleviate acne symptoms.

Hereinafter, a method for manufacturing a dentifrice composition containing a cornstarch according to the present invention as a natural abrasive agent comprises the following four steps, which will be described with reference to FIG.

(A) Abrasive wetting step (R-1):

First, a raw fine powder of 3 to 12 wt%, which is obtained by wet pulverizing a rice bran, drying and shredding and having an average particle size of 5 to 15 μm and a proportion of 10 μm or less of at least 40% by volume and a proportion of 25 μm or less of at least 90% D-sorbitol solution, ethylene glycol, propylene glycol, or any of the mixed wetting agents 20 (a) and 20 (b) is added to the precipitated calcium carbonate, calcium hydrogen phosphate hydrate, aluminum hydroxide, precipitated silica, hydrated silicic acid, To 40% by weight is added and wetted by stirring.

(B) Natural surfactant addition step (R-2):

0.1 to 5% by weight of a mixture of xylitol, steviol glycoside, sage extract, erythritol, licorice acid or any mixture thereof as a sweetening agent in a wetted abrasive mixture, a natural surfactant sodium cocoyl glutamate as a foaming agent and / or an apple wash 0.1 to 3 0.05 to 5% by weight of allantoin chlorohydroxyaluminum and aminocaproic acid, which are antifogging agents as an efficacy enhancer, are homogeneously mixed.

(C) Viscous application step (R-3):

0.1 to 10% by weight of purified water and sodium carboxymethyl cellulose (CMC), carrageenan, xanthan gum, gum arabic or any mixture thereof as a binder is added to the homogeneously mixed mixture and the mixture is stirred to give a viscosity as a tooth paste formulation .

(D) Natural preservative addition step (R-4):

0.1 to 1% by weight of a natural essential oil as a natural flavoring agent or a natural flavoring agent, 0.1 to 1% by weight of lemon grass oil or a basil oil, a L-menthol-rich peppermint or peppermint oil, or a mixture thereof, and a propolis and / Or 0.1 to 5% by weight of grapefruit seed extract.

On the other hand, the above-mentioned fine micropowder powder which has been pulverized after wet pulverization and drying can be further pulverized by using a vacuum vacuum cyclone mill or a powder mixer.

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to Examples, Comparative Examples and Test Examples, but the present invention is not limited thereto.

Comparative Example 1

Rice husks grown in Chuncheon were purchased, and rice husk (rice bran), which is a good byproduct obtained in the process of rice padding by using a friction type polishing machine and a grinding type polishing machine, was prepared.

The particle size of the untreated rice bran was measured with a Microtrac (particle size analyzer S3500) at a value between 0.1 μm and 500 μm, and the mean value was found to be 72.36 μm.

FIG. 1 shows the particle size analysis data for the ground fine grain of Comparative Example 1. In the particle size graph, the left side of the Y axis (Q3) shows a cumulative percentage section and the right side (dQ3) It is.

Example 1

The fine powder having an average particle diameter of 72.36 μm in Comparative Example 1 was wet pulverized at 800 rpm for 1 hour using an Attrition Mill and then naturally dried at room temperature to remove volatile components and moisture and to crush the coarse sample after the drying process Treated at 14,000 rpm for 20 minutes using a Powder Mixer to obtain a fine powder.

As a result of measurement by Microtrac, the average particle diameter was 11.36 탆, the ratio of less than 10 탆 was 52.4% by volume, and the ratio of less than 25 탆 was 97.9% by volume.

Fig. 2 shows a particle size analysis data chart of the rice bran micropowder powder of Example 1. Fig.

Example 2

The fine powder having an average particle size of 72.36 μm in Comparative Example 1 was wet pulverized at 800 rpm for 2 hours using an Attrition Mill and then dried naturally at room temperature to remove volatile components and moisture and to crush the coarse sample after the drying process Powder Mixer at 14,000 rpm for 10 minutes and then treated with a Cyclone Mill equipped with a vacuum system for 15 minutes to break up into fine powder.

As a result of measurement with Microtrac, the average particle diameter was 7.69 탆, the ratio of 10 탆 or less was measured to be 76.5% by volume, and the ratio of 25 탆 or less was measured to be 99.9% by volume.

It was found that the result of the disintegration treatment was excellent and optimum for addition to the dentifrice composition.

Fig. 3 shows particle size analysis data for the rice germ powder of Example 2.

Example 3

In Example 2, the same procedure was followed except that the Cyclone Mill with a vacuum system was used and treated at 14,000 rpm for 30 minutes using only the Powder Mixer without processing.

As a result of measurement by Microtrac, the average particle diameter was 7.69 탆, the ratio of 10 탆 or less was 76.5% by volume, and the ratio of 25 탆 or less was 99.9% by volume.

Overall summary:

4 is a graph showing comparison and analysis of particle size distribution of Comparative Example 1 and Examples 1 and 2. In FIG. 4, the orange graphs are Examples 2 and 3, the black graph is Example 1, The yellow graph is Comparative Example 1 for raw rice bran.

4, the ratio of particles having a particle diameter of 10 μm or less was 8.6% by volume in Comparative Example 1, 52.4% by volume in Example 1, and 76.5% by volume in Examples 2 and 3.

On the other hand, it was judged to be most suitable for use as an abrasive for the dentifrice composition of Example 2 in consideration of the whole decomposition state.

The processing procedures and methods for the raw cores of Examples 1 to 3 and Comparative Example 1 are summarized in Table 2 below.

Example 1 Example 2 Example 3 Comparative Example 1 Rice bran 1.Attrition Mill
(800 rpm * 1H)
2.Powder Mixer
(14000 rpm x 20 min) 1.Attrition Mill
(800 rpm * 2H)
2.Powder Mixer
(14000 rpm x 10 min)
3. Cyclone Mill
(With vacuum system) 1.Attrition Mill
(800 rpm * 2H)
2.Powder Mixer
(14000 rpm x 30 min) Fine grinding
(No further milling after one round at the mill) particle 11.36 탆 7.69 탆 7.69 탆 72.36 탆

Examples 4 to 6 and Comparative Examples 2 and 3: Formulation of dentifrice composition

A dentifrice composition was formulated at the compositional components and composition ratios as shown in the following Table 3, Example 4 was the case of using the microgranular fine powder of Example 1, Example 5 was the case of using the microgranular fine powder of Example 2 And Example 6 is the case of using the rice bran micropowder powder of Example 3 and Comparative Example 2 is the case of using the unmachined rice bran as in Comparative Example 1, , And the rest of the composition components are essentially the same except that the precipitated calcium carbonate is 30% by weight in Comparative Example 3, and the unit of each composition ratio is% by weight.

Example 4 Example 5 Example 6 Comparative Example 2 Comparative Example 3 Precipitated calcium carbonate 20.00 20.00 20.00 20.00 30.00 Aminocaproic acid 0.05 0.05 0.05 0.05 0.05 Rice bran 5.00
(Example 1) 10.00
(Example 2) 5.00
(Example 3) 5.00
(Comparative Example 1) -
(No rice added) Allantoin chloro
Hydroxy aluminum 0.10 0.10 0.10 0.10 0.10 Hydrogen phosphate
Calcium hydrate 0.05 0.05 0.05 0.05 0.05 D-sorbitol solution 30.00 30.00 30.00 30.00 30.00 glycerin 7.80 7.80 7.80 7.80 7.80 Carboxymethyl
Sodium cellulose Qs (qs) Qs (qs) Qs (qs) Qs (qs) Qs (qs) Coco
Sodium glutamate Qs (qs) Qs (qs) Qs (qs) Qs (qs) Qs (qs) Xylitol 0.10 0.10 0.10 0.10 0.10 Steviol glycoside 0.20 0.20 0.20 0.20 0.20 L-menthol 0.30 0.30 0.30 0.30 0.30 Grapefruit seed extract 0.40 0.40 0.40 0.40 0.40 Propolis extract 0.10 0.10 0.10 0.10 0.10 Lemon grass oil Qs (qs) Qs (qs) Qs (qs) Qs (qs) Qs (qs) peppermint oil Qs (qs) Qs (qs) Qs (qs) Qs (qs) Qs (qs) Purified water Balance Balance Balance Balance Balance system 100 100 100 100 100

Experimental Example 1: Sensory evaluation on polishing effect

For the sensory evaluation of the abrasive effect, 25 persons of 20-40 adult men and women were divided into 5 groups of 5 persons, and the dentifrice compositions of Examples 4-6 and Comparative Examples 2 and 3 shown in Table 2 were applied for 5 days Three times a day, and the degree of feeling of toothpaste abrasion force after use was evaluated according to the following 10-point scaling method.

10 points: Very strong polishing effect

7 points: strong abrasive effect

5 points: The polishing effect is usually

3 points: weak polishing effect

1 point: very weak polishing effect

The results are shown in Table 4 below.

Example 4 Example 5 Example 6 Comparative Example 2 Comparative Example 3 Sensory evaluation
(Polishing effect) 6.6 8.2 7.2 5.4 3.6

Experimental Example 2: Measurement of average odor reduction rate and sensory evaluation on halitosis inhibitory ability

Example 4 In order to 6 and Comparative Examples 2 and 3 of measuring the breath inhibitory effect on dentifrice composition, kidney disease, diabetes ¹⁾ does not suffer from hydrogen sulfide and methyl mercaptan, the strength of the as determined by measuring the Breathview breath moderate ^{2 )} adult male and female adults were selected as experimental subjects.

The test method provided the same evening to all 25 subjects of adult men and women with moderate levels of halitosis. After 30 minutes of eating, the toothpaste compositions of Examples 4 to 6 and Comparative Examples 2 and 3 were perfused with a toothpaste composition, followed by Breathview The bad breath measurement was carried out in accordance with the criteria shown in Table 5 below, and the sensory evaluation was also carried out. Breathview hydrogen sulfide measurements were expressed in ppb units, and the odor reduction rate of each subject was calculated by converting the mean odor value of each subject into a percentage index.

Sensory evaluation criteria Breathview (Twin Breasor II) score Strength of halitosis ng / 10ml ppb Hydrogen sulfide concentration Methyl mercaptan concentration Hydrogen sulfide concentration Methyl mercaptan concentration 0 No smell H2S ? 1.50 MM ? 0.50 H2S ≤ 112 MM ≤ 26 2 Recognized as smell H2S ? 1.50 MM ? 0.50 H2S ? 112 MM ≒ 26 4 Recognized as odor 1.50? H2S <3.00 0.50 &lt; MM & lt; 1.50 112? H2S & lt; 224 26 ≤ MM <79 6 Recognized as strong odor 3.00? H2S <6.00 1.50 < MM & lt; 4.50 224? H2S <448 79 ≤ MM <238 8 Recognized as strong odor that can be tolerated 6.00? H2S <12.00 4.50 < MM & lt; 9.00 448? H2S & lt; 896 238 < MM & lt; 476 10 Recognized as an unbearable strong odor 12.00? H2S 9.00 ≤ MM 896 ≤ H2S 476 ≤ MM

Note) 1) Patients with kidney disease or diabetes have high levels of ketone and ammonia, resulting in chronic bad breath.

       Note) 2) <Moderate standard>

Identifiable as odor: 112 ≤ H ₂ S∠224 (unit: ppb)

Can be recognized as strong odor: 224 ≤ H ₂ S∠448 (unit: ppb)

In the experiment of measuring the odor reduction rate of the dentifrice compositions of Examples 4 to 6 and Comparative Examples 2 and 3 as measured by Breathview, among the odorant values measured at a moderate level of hydrogen sulfide among the odor measurement values of 30 minutes after the meal, The value between 112 H ₂ S < 448, which is the value between recognizable strong odor, was obtained. Then, 25 adult males and 5 females having the same range of bad breath were divided into 5 groups, and the same toothbrush was applied to the toothbrushes. The toothbrushes were rubbed with the same toothbrush to measure hydrogen sulfide of Examples 4 to 3 and Comparative Examples 2 and 3, The reduced value of halitosis of the measured value is converted into a percentage index, and is shown in Table 6 below.

Subject group
(Unit: 5 people per group) 30 minutes after meal
(Unit: ppb) 10 minutes after brushing
(Unit: ppb) Bad breath reduction rate
(unit : %) Example 4 445 111 260 93 264 88 332 121 175 98 system 1476 511 65.30% Example 5 224 87 429 62 135 22 362 101 147 55 system 1297 327 75.70% Example 6 272 97 129 24 153 62 348 114 142 29 system 1044 326 68.80% Comparative Example 2 187 115 154 71 202 75 339 163 117 16 system 999 440 56.90% Comparative Example 3 421 158 333 182 191 150 154 76 173 149 system 1272 715 45.40%

The dentifrice composition including the microgranular fine powder of Examples 4 to 6, the dentifrice composition including the microgranulated microcrystalline of Comparative Example 2, and the microgranular dentifrice composition of Comparative Example 3, The halitosis reduction rates of five persons per group are shown in Table 7 below and the graphs in Table 7 are shown in Figs. 5A and 5B, Figs. 6A and 6B, Figs. 7A and 7B, Figs. 8A and 8B, 9b.

30 minutes after meal 10 minutes after brushing Bad breath reduction rate (%) Example 4 332 121 63.6 Example 5 362 101 72.1 Example 6 348 114 67.2 Comparative Example 2 339 163 51.9 Comparative Example 3 333 182 45.3

In addition, sensory evaluation of halitosis inhibition rate was performed in the same manner as in the case of the subject who measured the reduction rate of bad breath related to the bad breath control ability, and the average value of the criteria was calculated as 10 points. The results are shown in Table 8 below.

10 points: Very good for bad breath control

7 points: Good effect to suppress bad breath

5 points: Bad breath suppression effect is usually

3 points: Bad breath suppression effect

1 point: Bad breath suppression effect is very poor

Example 4 Example 5 Example 6 Comparative Example 2 Comparative Example 3 Sensory evaluation
(Bad breath suppressing ability) 8.2 9.6 8.8 7.6 6.2

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. Various changes and modifications can be made by those skilled in the art without departing from the spirit and scope of the invention Which is also within the scope of the present invention.

Claims (5)

The raw material containing rice bran fine particles as an abrasive with an average particle diameter of 5 to 15 μm and a proportion of 10 μm or less of at least 40% by volume and a proportion of 25 μm or less of at least 90% by volume as a natural abrasive &Lt; / RTI &gt; The dentifrice composition according to claim 1, wherein the raw rice flour is contained in an amount of 3 to 12% by weight based on the total composition. The method according to claim 1, wherein 20 to 60% by weight of the abrasive containing 3 to 12% by weight of the rice flour fine powder, 20 to 40% by weight of the wetting agent, 0.1 to 10% , 0.1 to 3% by weight of a natural surfactant, 0.1 to 1% by weight of a natural flavor agent, 0.05 to 5% by weight of an anti-fouling agent as an effect enhancing agent, 0.1 to 5% by weight of a natural preservative, As a natural abrasive. (A) rice bran powder having an average particle diameter of 5 to 15 占 퐉, a proportion of 10 占 퐉 or less of at least 40% by volume and a proportion of 25 占 퐉 or less of at least 90% by volume, obtained by wet grinding rice bran, fine polystyrenes and fine polystyrenes and from 8 to 57% by weight of at least one abrasive selected from the group consisting of precipitated calcium carbonate, calcium hydrogenphosphate hydrate, aluminum hydroxide, precipitated silica and hydrated silicic acid, Adding 20 to 40% by weight and wetting with stirring;
(B) homogeneously mixing 0.1 to 5% by weight of a sweetener, 0.1 to 3% by weight of a natural surfactant as a foaming agent, and 0.05 to 5% by weight of an anti-fouling agent as an effect enhancing agent, in a wetted abrasive mixture;
(C) adding purified water and 0.1 to 10% by weight of a binder to the mixed mixture and stirring to give a viscosity;
(D) mixing 0.1 to 1% by weight of a natural flavoring agent and 0.1 to 5% by weight of a natural preservative in a viscometric mixture,
A method of producing a dentifrice composition containing rice bran as a natural abrasive. 5. The method of manufacturing a dentifrice composition according to claim 4, wherein the micropowder microparticles obtained by wet pulverization and drying are further subjected to further pulverization under reduced pressure vacuum.

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