JP2013155169A - Dentifrice composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dentifrice composition, using a specific polishing agent, simultaneously realizing both polishing and foul mouth removability, getting rid of causes of feeling no sweetness, and also preventing gingival diseases and the like without using any components harmful to human body.SOLUTION: The dentifrice composition containing pozzuolana (polishing agent) is provided, also containing at least one additive selected from the group consisting of aminocaproic acid (anti-inflammatory agent), allantoin chlorhydroxyaluminum (anti-inflammatory agent), glycerol (moisturizing agent), polyethylene glycol (surfactant), D-sorbitol (moistening agent), carboxymethylcellulose sodium (thickening agent), cocamidopropyl betaine (foaming agent), xylitol (sweetener), stevioside (sweetener), peppermint oil (refreshment) and L-menthol (flavoring agent).

Description

  The present invention relates to a dentifrice composition that is excellent in abrasiveness and halitosis removal properties and that can retain the sweet taste of the tongue even after brushing.

In general, calcium carbonate (CaCO ₃ ), silica (SiO ₂ ), calcium hydrogen phosphate (CaHPO ₄ .2H ₂ O) and the like are known as abrasives used for toothpaste. Such raw materials have a polishing effect, but are insufficient for removing bad breath. Therefore, in addition to abrasives, green tea, hydrogen peroxide or a flavoring agent effective for removing bad breath is added to normal toothpaste.

  Moreover, in general toothpaste, sodium lauryl sulfate (Sodium Lauryl Sulfate) is used as a foaming agent (or surfactant) (Patent Documents 1 and 2 described later). This raw material is for improving the tooth brushing performance by the foaming effect by the surface active action.

  In addition, parabens with bactericidal action, saccharin as a sweetening agent, artificial pigments, artificial flavors and the like are added. Paraben is known to induce skin diseases, central nervous system paralysis, cancer, and the like because it has the property of suppressing the growth of bacteria, yeast, mold, etc. even at concentrations that are considered to cause little harm to the human body. In particular, methyl paraoxybenzoate (methylparaben) cuts bacterial DNA and kills it, but if you ingest it, human genes may be destroyed, cells may die, or gene mutations may occur. is there.

  Saccharin is carcinogenic and can cause gastrointestinal and kidney damage. Artificial pigments can cause anxiety and irritation, distract attention, induce attention deficit and excessive behavioral disorders, cause problems with atopy and allergies, and can also cause cranial nerve abnormalities The research result of the contents is also announced. Artificial fragrances are also made by chemically synthesizing them, stimulating hormones to give them a unique scent.

  In the above-mentioned toothpaste, it is necessary to add an additive for removing bad breath in addition to the abrasive, so that the material cost increases and the preparation work is required.

  Moreover, when the above-mentioned sodium lauryl sulfate is used in toothpaste, the taste receptor that senses the sweetness of the tongue is blunted. Therefore, when fruits are eaten after toothbrushing, sourness is strongly felt and bitterness is also felt. This is inconvenient because the sweetness of fruits such as bananas cannot be felt after brushing.

  In order to solve these problems, alternative raw materials to replace sodium lauryl sulfate have been studied. However, since alternative foaming agents have weak foaming power or are difficult to produce, the current situation is that sodium lauryl sulfate is still used. It is.

  Moreover, it has been found that the above-mentioned parabens, saccharin, artificial fragrances and the like are harmful to the human body.

  Accordingly, an object of the present invention is to simultaneously achieve polishing and removal of bad breath using a specific abrasive in a dentifrice (or toothpaste), to eliminate the cause of the inability to feel sweetness, and to the human body. It is to prevent gum diseases and the like without using harmful ingredients.

  That is, the present invention is a dentifrice composition containing volcanic ash, comprising aminocaproic acid, allantochlorohydroxyaluminum, glycerin, polyethylene glycol, D-sorbitol, sodium carboxymethylcellulose, and cocamidopropyl beddain. And a dentifrice composition further containing at least one additive selected from the group consisting of xylitol, stevioside, peppermint oil, and L-menthol.

  According to the present invention, since the above-mentioned volcanic ash includes both an abrasive component and a bad breath removing component (deodorant component), polishing and bad breath removal can be realized simultaneously only by including volcanic ash. can do. Therefore, the material cost of the dentifrice is reduced, and the blending operation becomes easy.

  In addition, none of the above-mentioned additives other than volcanic ash has the effect of making sweetness even after eating fruit, etc., and is not harmful to the human body. It also prevents gum disease, periodontal disease, etc. The performance of the dentifrice, such as imparting a refreshing feeling, can be further improved.

  In the dentifrice composition of the present invention, in order to realize the effects of polishing and bad breath removal at the same time, the content of the above volcanic ash is 0.1 to 20 parts by mass with respect to the entire dentifrice composition. Is good. When the content is less than 0.1 parts by mass, the above-described effects are hardly exerted. When the content exceeds 20 parts by mass, the polishing action is too strong and the gums are likely to be worn. This content is preferably 1 to 15 parts by mass, more preferably 5 to 15 parts by mass, and most preferably 10 parts by mass or before and after.

The volcanic ash is preferably composed of a fine shirasu having a particle size of 40 μm or less, and particularly 10 μm or less (and an ultrafine shirasu having a particle size of 2 μm or less). This is because the fine shirasu has a sufficient particle size to give a polishing effect, a dissimilar substance removal effect between teeth and a whitening effect, and an anti-plaque (plaque removal) effect due to the polishing effect This is because it has excellent components such as SiO ₂ and also has mineral components such as MgO having a deodorizing effect.

  Such a fine shirasu can be obtained by pulverizing a volcanic glassy deposit with a pulverizer to obtain a fine particle size of 10 μm or less. And it is good to make a particle size uniform by the rotary sieve which sorts a particle size using centrifugal force. The above-mentioned ultrafine shirasu is obtained by the above-mentioned pulverization and selection of the particle size by sieving while the particle size of a general shirasu balloon is 10 μm.

  Since the surface of the fine shirasu is charged with negative ions, it also has an action of attracting and removing adhering impurities on the surfaces of teeth and gums bearing positive ions. This produces an excellent polishing effect and synergistic effect due to the ultrafine particles. In addition, since the ultrafine shirasu is porous, it itself spreads to the details of the surface of the object, and at the same time it can fully exert its action while adsorbing and holding the other additives mentioned above. it can.

  To describe the effects of other additive components other than volcanic ash, aminocaproic acid has an excellent effect on anti-inflammation and anti-bleeding, and if a certain amount of this component is added, it has an effect on gum inflammation.

  Allantoin chlorohydroxyaluminum has anti-inflammatory and allergic effects of allantoin, and the greatest feature of colorless crystalline powder is that it directly or indirectly activates cell activity. is there. It is excellent in sedation and is used as a therapeutic agent for gastrointestinal ulcer, and is also used in cosmetics due to its excellent pharmacological action and safety. Anti-inflammatory effect (anti-inflammatory effect) and anti-allergy promotes the growth of new tissues, so it is effective in treating damaged skin. A plant extract with acne, treatment of sensitive skin, and sedation, found at the root of perennials and known to not induce allergies. Like aminocaproic acid, it is effective for gum diseases, periodontal disease, and gum convergence.

  Xylitol is a natural sweetener and has a function of preventing dental caries. Xylitol inhibits mutans and promotes salivary secretion in the oral cavity. Saliva contains a calcium component that is essential for tooth restoration, and the smoother the secretion of saliva, the more the caries are suppressed, so xylitol has the effect of suppressing caries by inducing the smooth secretion of saliva. There is also an effect of preventing bacteria.

  Peppermint oil is a light yellow liquid obtained by cooling and purifying oil obtained by drying and distilling mint leaves and vines, and has a unique aroma and acidity and is used as a refreshing agent for cosmetics, foods, medical products, etc. . Effective for removing stomach and gas.

  As described above, it is desirable to add aminocaproic acid, allantochlorohydroxyaluminum, xylitol and peppermint oil as essential components together with volcanic ash (particularly volcanic ash shirasu). In other words, the addition of volcanic ash shirasu with excellent adsorption capacity and abundant mineral components provides an effective tooth polishing and bad breath removal effect, effective for oral cleansing, bad breath removal, and plaque removal (anti-plaque) And gingivitis, periodontitis (alveolar abscess), periodontal disease and gums while eliminating components harmful to the human body by adding medicinal ingredients such as aminocaproic acid, allantochlorhydroxyaluminum, xylitol and peppermint oil It has an excellent effect on preventing inflammation and caries. Moreover, the sweetness of the fruit can be felt even if the fruit is eaten after toothpaste without using the chemical foaming agent used in general toothpaste.

  In addition to the above components, glycerin is a moisturizing agent, polyethylene glycol is a surfactant, D-sorbitol is a wetting agent, sodium carboxymethylcellulose is a thickening agent, and cocamidopropylbedine is a cation interface with air bubbles. The active agent, stevioside functions as a sweetener, and L-menthol functions as a flavor.

  Of these, in particular, cocamidopropyl bedain does not impair the function of the taste receptor that senses the sweetness of the tongue. Therefore, it can be added to the sodium lauryl sulfate described above to sufficiently maintain the bubble force. In addition, there is no cause for the sweetness to be felt, and the sweetness can be enjoyed even when eating fruit after brushing. The content of this cocamidopropyl beadine is preferably 1 to 5 parts by mass with respect to the entire dentifrice composition in order to exhibit the above effects. When the content is less than 1 part by mass, the above effect is hardly achieved. When the content exceeds 5 parts by mass, the foaming action is too strong. This content is preferably 1 to 3 parts by mass, and most preferably 2 parts by mass or before and after.

  In addition, if toothpaste is made by a general method, a bitter taste will come out, so it is better to add stevioside to make it feel sweet. That is, since stevioside and the like are added to bring out the inherent sweetness of the toothpaste, its action is different from the sweetness-holding action of cocamidopropylbedine added as a foaming agent.

  Next, the present invention will be described in detail with reference to examples.

  First, the volcanic ash used as an abrasive in the toothpaste (or dentifrice) composition of this example will be described. This volcanic ash was collected in the Yoshida area of Kagoshima, Japan and is called “Yoshida Shirasu” in Japan.

This volcanic ash is known to have the following composition by component analysis (% represents mass%).
SiO ₂ : 73.3%
TiO ₂ : 0.37%
Al ₂ O ₃ : 13.4%
Fe ₂ O ₃ : 2.29%
MgO: 0.38%
CaO: 1.75%
Na ₂ O: 3.29%
K ₂ O: 3.56%
H ₂ O: 1.66% (amount evaporated when dried)

Looking at the above components, this volcanic ash is composed mainly of SiO ₂ , TiO ₂ , Al ₂ O _3, etc., which have a polishing effect, as well as mineral components such as MgO, CaO, Na ₂ O, which have a deodorizing effect. It can be seen that the amount is contained.

  Here, the polishing degree will be described. When the polishing degree of the toothpaste is measured by a known tooth wear degree (polishing degree) test method, 50 or less is a low polishing degree, 50 to 100 is an intermediate polishing degree, and 100 or more is a high polishing degree. Rated with degrees.

  The above Yoshida Shirasu is refined after pulverizing volcanic ash to a particle size of 2000 mesh (6.4 μm), and shows an intermediate polishing degree of about 70, so it is compared with a high polishing degree of 100 or more. Thus, it was confirmed that there is little possibility of inducing gum abrasion, and it can be used safely and smoothly. Other volcanic ash having the same action and function as Yoshida Shirasu can be used.

Further, this Yoshida shirasu was subjected to an ammonia deodorization experiment by a generally employed ammonia (NH ₃ ) deodorization experiment method: KICM-FIR-1085 (2006), and the deodorization rate after 60 minutes was 80% or more. . This proves that ammonia which is a cause of bad breath can be sufficiently removed.

  Next, a toothpaste (or dentifrice) composition comprising the components shown in Table 1 below was produced according to a conventional method with the addition of various additives.

  That is, water and D-sorbitol are put in a production kettle and heated to 60 ° C., and after this heating, an abrasive is added and stirred, sodium carboxymethylcellulose and silicon dioxide are added and stirred, and finally a foaming agent. Etc. were added and stirred. In this case, aminocaproic acid and allantochlorohydroxyaluminum as medicinal components, glycerin as a humectant, polyethylene glycol as a surfactant, xylitol as a sweetener, peppermint oil as a refreshing agent, and L-menthol as a fragrance, for example, Table 1 It added in the range of 1-10 mass parts with respect to the composition of.

  About each dentifrice consisting of the said component, the grinding | polishing test was done by the well-known tooth abrasion degree (polishing degree) test method. The results are shown in Table 2 below.

  In this test, the tooth of a person whose tooth polishing degree (tooth wear degree) was extracted was verified in vitro, and the degree of wear of toothpaste was measured by the area of the cut surface of the sample tooth worn by tooth brushing. The test method of toothpaste (tooth wear degree) of toothpaste used here is the surface-profile method of wear tooth surface, but in addition to this, the wear tooth radiation measurement method (Radio- Test methods such as tracer method and weight-loss technique may be used. At this time, Surftest sv-2000 manufactured by Mitutoyo was used as a surface contour measuring machine.

  Specifically, in the process of brushing teeth, a tension of 300 g is applied to the surface of the sample tooth piece (which is subjected to the test on dentin after removing the tooth denaturation of the extracted tooth), and 200 reciprocations per minute. About 3000 times of tooth brushing was performed. The device used at this time used a spring device that maintained a tension of 300 g on the electric toothbrush. Then, after separating the sample tooth piece, the worn surface is measured again with a surface profiler, and the worn area of the sample tooth piece is measured with the area machine on the recorded recording paper. The surface area of the specimen tooth piece worn by the toothpaste was calculated.

  From these results, it was confirmed that the dentifrices of Examples 1 and 2 according to the present invention showed an intermediate degree of polishing of about 70, so that there is little possibility of inducing gum abrasion and can be used safely and smoothly. .

  Moreover, about each said dentifrice, the ammonia which is a cause of bad breath was measured and the bad breath removal test was done using the well-known bad breath tester (mBA-21 by the Plastec company). In this bad breath tester, the numerical value (degree of bad breath) is expressed from 1 to 100 according to the ammonia content. The higher the numerical value, the higher the ammonia concentration (ppm). In general, for a normal person, the basic value before brushing is about 30. Thirty men and women were selected to use a dentifrice, and the values before and after use were measured. The measurement results are shown in Table 3 below.

  From the above results, it can be seen that Examples 1 and 2 based on the present invention are more excellent in bad breath removing power than each comparative example.

  Furthermore, 10 each of the above-mentioned toothpastes were used, and after eating the teeth, fruits such as bananas were eaten, and it was tested whether or not the sweetness of the fruits was felt. The results are shown in Table 4 below.

  From these results, it was found that the toothpaste of Example 1 based on the present invention can feel the sweetness sufficiently when eating fruit after brushing, whereas the comparative examples do not feel sweetness.

  In addition, each of the dentifrices of Examples 1 and 2 based on the present invention is not harmful to the human body, and also prevents the gum disease, periodontal disease, etc., and prevents the tooth decay and imparts a refreshing feeling. Can be further improved.

  Next, in Example 1 described above, the addition amounts of aminocaproic acid, allantochlorohydroxyaluminum, glycerin, polyethylene glycol, xylitol, peppermint oil, and L-menthol as additive components are specifically shown in Table 5 below. A specific dentifrice (numbers by weight) was produced.

  INDUSTRIAL APPLICABILITY The present invention can provide a dentifrice composition that is excellent in abrasiveness and halitosis removal properties, prevents gum diseases and the like without using ingredients harmful to the human body, and can retain a sweet feeling even after brushing.

JP 2010-155816 A (Specification, page 2, line 50 to page 3, line 1) JP-A-11-189518 (paragraph numbers [0011] and [0016] in the specification)

Claims (4)

  A dentifrice composition containing volcanic ash comprising aminocaproic acid, allantoinchlorohydroxyaluminum, glycerin, polyethylene glycol, D-sorbitol, sodium carboxymethylcellulose, cocamidopropylbedine, xylitol, and stevioside And a dentifrice composition further comprising at least one additive selected from the group consisting of peppermint oil and L-menthol.   The dentifrice composition according to claim 1, wherein aminocaproic acid, allantochlorohydroxyaluminum, xylitol and peppermint oil are essential components among the additives.   The dentifrice composition according to claim 1 or 2, comprising 0.1 to 20 parts by mass of the volcanic ash.   The dentifrice composition according to any one of claims 1 to 3, wherein the volcanic ash is made of fine shirasu.