KR20180069064A - 세포내 항원들에 대해 지시된 단일 도메인 항체 - Google Patents

세포내 항원들에 대해 지시된 단일 도메인 항체 Download PDF

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KR20180069064A
KR20180069064A KR1020187015132A KR20187015132A KR20180069064A KR 20180069064 A KR20180069064 A KR 20180069064A KR 1020187015132 A KR1020187015132 A KR 1020187015132A KR 20187015132 A KR20187015132 A KR 20187015132A KR 20180069064 A KR20180069064 A KR 20180069064A
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수난다 싱
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싱 바이오테크놀로지, 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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    • C07K16/1002—Coronaviridae
    • C07K16/1003—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2 or Covid-19]
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    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
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    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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  • General Physics & Mathematics (AREA)
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  • General Chemical & Material Sciences (AREA)
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KR1020187015132A 2015-11-02 2016-11-02 세포내 항원들에 대해 지시된 단일 도메인 항체 Withdrawn KR20180069064A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562249868P 2015-11-02 2015-11-02
US62/249,868 2015-11-02
PCT/US2016/060134 WO2017079314A2 (en) 2015-11-02 2016-11-02 Single domain antibodies directed against intracellular antigens

Publications (1)

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KR20180069064A true KR20180069064A (ko) 2018-06-22

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KR1020187015132A Withdrawn KR20180069064A (ko) 2015-11-02 2016-11-02 세포내 항원들에 대해 지시된 단일 도메인 항체

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US (4) US10369223B2 (enExample)
EP (1) EP3371215A4 (enExample)
JP (2) JP6918005B2 (enExample)
KR (1) KR20180069064A (enExample)
CN (2) CN113512112A (enExample)
AR (1) AR106556A1 (enExample)
AU (1) AU2016349876B2 (enExample)
BR (1) BR112018008840B1 (enExample)
CA (1) CA3002239A1 (enExample)
IL (1) IL258742B (enExample)
MX (1) MX2018005154A (enExample)
RU (3) RU2742248C2 (enExample)
TW (1) TWI746473B (enExample)
WO (1) WO2017079314A2 (enExample)

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US20170267784A1 (en) 2014-10-23 2017-09-21 Singh Molecular Medicine, Llc Single domain antibodies directed against intracellular antigens
US12383634B2 (en) * 2019-07-24 2025-08-12 Korea Basic Science Institute Single domain antibody targeting αVβ3 integrin
CN111234019B (zh) * 2020-01-16 2022-06-24 佛山汉腾生物科技有限公司 抗ctla-4纳米抗体、药物组合物及其应用
CN111184864B (zh) * 2020-01-20 2022-01-14 武汉大学 Alox12特异性抑制剂在制备治疗非酒精性脂肪肝病和/或ⅱ型糖尿病的药物中的应用
CN113214392B (zh) * 2020-12-30 2022-07-01 中国人民解放军海军军医大学 抗水母毒素纳米抗体ky031、制备方法及用途
CN115414482A (zh) * 2022-07-13 2022-12-02 同济大学 Stat3信号通路抑制剂的应用

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