KR20180050798A - Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof - Google Patents
Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof Download PDFInfo
- Publication number
- KR20180050798A KR20180050798A KR1020160147269A KR20160147269A KR20180050798A KR 20180050798 A KR20180050798 A KR 20180050798A KR 1020160147269 A KR1020160147269 A KR 1020160147269A KR 20160147269 A KR20160147269 A KR 20160147269A KR 20180050798 A KR20180050798 A KR 20180050798A
- Authority
- KR
- South Korea
- Prior art keywords
- extract
- skin
- weight
- present
- homeostatic
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims abstract description 95
- 239000000203 mixture Substances 0.000 title claims abstract description 88
- 239000002537 cosmetic Substances 0.000 title claims abstract description 52
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 19
- 230000008491 skin homeostasis Effects 0.000 title abstract description 11
- 231100000956 nontoxicity Toxicity 0.000 title description 2
- 241000234299 Zingiberaceae Species 0.000 title 1
- 230000003000 nontoxic effect Effects 0.000 claims abstract description 36
- 231100000252 nontoxic Toxicity 0.000 claims abstract description 34
- 230000003284 homeostatic effect Effects 0.000 claims description 30
- 244000060701 Kaempferia pandurata Species 0.000 claims description 22
- 241000196324 Embryophyta Species 0.000 claims description 20
- 235000016390 Uvaria chamae Nutrition 0.000 claims description 19
- 235000006886 Zingiber officinale Nutrition 0.000 claims description 19
- 235000008397 ginger Nutrition 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 8
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 8
- 244000004281 Eucalyptus maculata Species 0.000 claims description 8
- 244000082204 Phyllostachys viridis Species 0.000 claims description 8
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 8
- 239000011425 bamboo Substances 0.000 claims description 8
- 229940069765 bean extract Drugs 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 240000004922 Vigna radiata Species 0.000 claims description 7
- 235000010721 Vigna radiata var radiata Nutrition 0.000 claims description 7
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 claims description 7
- 239000003995 emulsifying agent Substances 0.000 claims description 7
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims description 6
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims description 6
- 244000042664 Matricaria chamomilla Species 0.000 claims description 6
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 6
- 229940094952 green tea extract Drugs 0.000 claims description 6
- 235000020688 green tea extract Nutrition 0.000 claims description 6
- 239000008213 purified water Substances 0.000 claims description 6
- 240000007594 Oryza sativa Species 0.000 claims description 5
- 235000007164 Oryza sativa Nutrition 0.000 claims description 5
- 230000003750 conditioning effect Effects 0.000 claims description 5
- 235000012907 honey Nutrition 0.000 claims description 5
- 235000009566 rice Nutrition 0.000 claims description 5
- 235000011203 Origanum Nutrition 0.000 claims description 4
- 240000000783 Origanum majorana Species 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000013355 food flavoring agent Nutrition 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 239000002981 blocking agent Substances 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000003009 skin protective agent Substances 0.000 claims description 3
- 240000008886 Ceratonia siliqua Species 0.000 claims description 2
- 235000013912 Ceratonia siliqua Nutrition 0.000 claims description 2
- 239000004909 Moisturizer Substances 0.000 claims description 2
- 230000001333 moisturizer Effects 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 239000003352 sequestering agent Substances 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- 240000002853 Nelumbo nucifera Species 0.000 claims 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims 1
- 244000273928 Zingiber officinale Species 0.000 claims 1
- 244000013123 dwarf bean Species 0.000 claims 1
- 230000002431 foraging effect Effects 0.000 claims 1
- 239000012258 stirred mixture Substances 0.000 claims 1
- 231100000419 toxicity Toxicity 0.000 abstract description 16
- 230000001988 toxicity Effects 0.000 abstract description 16
- 229930193739 panduratin Natural products 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 8
- 230000006870 function Effects 0.000 abstract description 8
- 210000004927 skin cell Anatomy 0.000 abstract description 6
- 230000002087 whitening effect Effects 0.000 abstract description 6
- 201000004624 Dermatitis Diseases 0.000 abstract description 4
- 230000003078 antioxidant effect Effects 0.000 abstract description 4
- 230000003712 anti-aging effect Effects 0.000 abstract description 3
- 230000009759 skin aging Effects 0.000 abstract description 3
- 230000037303 wrinkles Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 66
- 241000234314 Zingiber Species 0.000 description 19
- 210000004027 cell Anatomy 0.000 description 11
- 239000000419 plant extract Substances 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- 239000006071 cream Substances 0.000 description 8
- 239000006210 lotion Substances 0.000 description 8
- 239000000843 powder Substances 0.000 description 8
- 239000004480 active ingredient Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 102000008186 Collagen Human genes 0.000 description 5
- 108010035532 Collagen Proteins 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 5
- 229920001436 collagen Polymers 0.000 description 5
- 230000004054 inflammatory process Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 102000014156 AMP-Activated Protein Kinases Human genes 0.000 description 4
- 108010011376 AMP-Activated Protein Kinases Proteins 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 4
- 230000004069 differentiation Effects 0.000 description 4
- 210000002950 fibroblast Anatomy 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 230000037380 skin damage Effects 0.000 description 4
- 230000036559 skin health Effects 0.000 description 4
- 235000013412 Kaempferia pandurata Nutrition 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 229940059958 centella asiatica extract Drugs 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 3
- 235000009569 green tea Nutrition 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000013632 homeostatic process Effects 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 230000003020 moisturizing effect Effects 0.000 description 3
- 229930014626 natural product Natural products 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- 206010003645 Atopy Diseases 0.000 description 2
- 241000237858 Gastropoda Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 240000007817 Olea europaea Species 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 210000000577 adipose tissue Anatomy 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000003915 cell function Effects 0.000 description 2
- 230000010261 cell growth Effects 0.000 description 2
- 230000003833 cell viability Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 231100000263 cytotoxicity test Toxicity 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 230000019439 energy homeostasis Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 235000013376 functional food Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 239000012046 mixed solvent Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 239000004006 olive oil Substances 0.000 description 2
- 235000008390 olive oil Nutrition 0.000 description 2
- 230000036542 oxidative stress Effects 0.000 description 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 229940068968 polysorbate 80 Drugs 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- 241000258920 Chilopoda Species 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- -1 Hand Cream Substances 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000001145 Metabolic Syndrome Diseases 0.000 description 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
- 235000002725 Olea europaea Nutrition 0.000 description 1
- LYDZCXVWCFJAKQ-ZFGGDYGUSA-N Panduratin A Chemical compound OC1=CC(OC)=CC(O)=C1C(=O)[C@H]1[C@H](C=2C=CC=CC=2)CC=C(C)[C@H]1CC=C(C)C LYDZCXVWCFJAKQ-ZFGGDYGUSA-N 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 description 1
- 238000011481 absorbance measurement Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001153 anti-wrinkle effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000476 body water Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical class OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 239000013592 cell lysate Substances 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- JPCBEVHCIJLZFV-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO.CCCCC(O)CO JPCBEVHCIJLZFV-UHFFFAOYSA-N 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- LYDZCXVWCFJAKQ-UHFFFAOYSA-N nicolaioidesin A Natural products OC1=CC(OC)=CC(O)=C1C(=O)C1C(C=2C=CC=CC=2)CC=C(C)C1CC=C(C)C LYDZCXVWCFJAKQ-UHFFFAOYSA-N 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 230000008288 physiological mechanism Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000001626 skin fibroblast Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
본 발명은 피부 항상성 유지에 도움을 주는 화장료 조성물 및 그 제조방법에 관한 것으로, 특히 생강과 식물의 추출물을 함유하여 자외선에 의해 발현이 감소된 유전자의 발현을 정상화시킴으로써 피부세포의 항상성을 유지하고 생강과 식물의 독성을 제거한 무독성 화장료 조성물 및 그 제조방법에 관한 것이다. The present invention relates to a cosmetic composition that helps maintain skin homeostasis, and more particularly, to a cosmetic composition that maintains skin homeostasis by normalizing the expression of a gene containing an extract of ginger and a plant and having reduced expression by ultraviolet light, To a non-toxic cosmetic composition in which the toxicity of plants and plants is removed, and a process for producing the same.
피부는 최외각 층에 존재하여 외부로부터의 다양한 자극(화학물질, 대기오염, 건조한 환경자외선 등의 물리, 화학적 자극인자)에 대한 방어기능과 피부를 통한 체내 수분의 과도한 발산을 막는 보호기능을 담당하고 있으며, 이러한 기능은 피부각질층의 보호효과, 피부진피층의 수분보유량 및 피부에 원활한 혈액공급이 이루어질 때 피부항상성 유지를 위한 작용을 한다.The skin is in the outermost layer and it protects against various stimuli from outside (chemical, air pollution, physical and chemical stimulants such as ultraviolet rays in dry environment) and protects against excessive divergence of body water through skin This function works to protect the skin stratum corneum, to retain the moisture content of the skin dermal layer, and to maintain skin homeostasis when a smooth blood supply to the skin occurs.
이에, 피부의 정상적인 항상성 유지를 위한 방어기전을 높이기 위한 노력이 많이 이루어지고 있으나, 그러한 연구의 주타겟 분야는 피부의 보습과 미백 등으로 초점이 맞추어져 있는 실정이며, 자외선에 의한 피부손상으로부터 피부 건강을 유지하는데 도움을 주기 위한 연구는 미비한 실정이다.Thus, although efforts have been made to increase the defense period to maintain the normal homeostasis of the skin, the main target field of such studies is focusing on the moisturizing and whitening of the skin, There is little research to help them to maintain.
종래에 아토피성 피부질환에 효과를 가지는 판두라틴 에이(panduratin A) 또는 보에센베르기아 판두라타(Boesenbergia pandurata) 추출물에 대한 연구(한국 공개특허공보 10-2012-0113201, 2012.10.12. 공개)가 있으나, 아토피성 피부질환의 예방 및 치료에 국한되어 있을 뿐 피부의 항상성을 유지하기 위한 노력은 아직 시도된 바가 없는 바이다.Studies on panduratin A or Boesenbergia pandurata extracts which have been conventionally effective for atopic skin diseases (Korean Patent Laid-Open Publication No. 10-2012-0113201, published on October 12, 2012) However, it is limited to the prevention and treatment of atopic skin diseases, and efforts to maintain the homeostasis of the skin have not yet been attempted.
최근, 환경 친화적이고 자연지향적인 추세에 따라 화장품에 사용되는 유효성분들도 화학물질뿐만 아니라 식물 유래의 천연물이 그 유용성을 기반으로 하여, 피부에 부작용이 적은 천연 재료가 여러 가지 형태로 화장품에 배합되어 이용되고 있다. In recent years, according to the trend of environment-friendly and nature-oriented, effective substances used in cosmetics are based not only on chemical substances but also on plant-derived natural products, and natural materials having few side effects on the skin are mixed in cosmetics in various forms .
최근 문헌에 의하면, 생강과 식물, 특히 핑거루트(Fingerroot, Boesenbergia pandurata)의 뿌리에서 추출한 기능성 원료인 판두라틴(Panduratin)은 핑거루트의 뿌리에서 추출한 밝은 황갈색의 분말로서, 식품의약품안전처에서 2013년 건강기능식품의 기능성 원료로 인정되었으며 생리활성기능 2등급을 받은 바 있다.According to recent literature, ginger plants, especially the finger root functional raw material pandu Latin (Panduratin) extracted from the roots of (Fingerroot, Boesenbergia pandurata) is as a light tan powder extracted from the finger root roots in KFDA 2013 It has been recognized as a functional raw material for health functional foods and has received the second grade of physiologically active function.
핑거루트 추출분말인 판두라틴은 자외선에 의한 피부 손상으로부터 피부 건강을 유지하고 체내 에너지 항상성 유지를 위한 센서 단백질인 'AMPK(AMP-activated protein kinase)'를 활성화시켜 체지방을 감소하는 데 도움을 줄 수 있다고 판명되었다. 그러나 핑거루트 뿌리 추출분말인 판두라틴은 약간의 독성이 있어 사용에 주의를 요한다.Panduratin, a finger root extract powder, can help reduce body fat by activating the sensor protein 'AMP-activated protein kinase' (AMPK) to maintain skin health and maintain energy homeostasis from skin damage caused by UV rays . However, panduratin, a fungal root extract powder, is slightly toxic and requires caution in its use.
최근, 피부과학을 통한 생리적 메커니즘에 대한 연구 및 효능이 한 계 높은 새로운 소재로서 천연물로부터 유효성분을 추출 정제하는 연구로부터, 단순히 피부보호 차원에서 머물던 화장품이 그 효능에 있어서 피부개선의 범주까지 확대된 기능성 화장품에 대한 수요가 급증하고 있다.Recently, studies on physiological mechanisms through skin science and research on extracting and purifying active ingredients from natural products as a new high-efficacy new material have expanded the scope of skin improvement in the efficacy of cosmetic products that simply remain in the aspect of skin protection Demand for functional cosmetics is increasing rapidly.
특히, 기능성 화장품 중에서 한 제품에 두 가지 이상의 기능성을 갖는 복합기능성 화장품(예로서, 주름개선기능과 미백기능을 동시에 포함)에 대한 생산액 및 시장 성장률이 단일기능성 화장품에 비해 월등히 높게 나타나고 있다. In particular, the production amount and the market growth rate of a multi-functional cosmetic having two or more functionalities (for example, including a wrinkle-improving function and a whitening function at the same time) in one product among functional cosmetics are much higher than those of a single functional cosmetic product.
이러한 요구를 현재 시판되고 있는 대부분의 화장품이 받쳐주지 못하는 것이 사실이다. 이에, 핑거루트 추출분말을 이용하여 자외선에 의한 피부손상으로부터 피부 건강을 유지함으로써 피부의 항상성을 향상시킬 수 있으며, 핑거루트 추출물의 독성을 중화하여 무독성의 안전하고, 사용이 편리하며, 피부개선, 피부진정 및 피부보습 등 복합적인 피부 항상성 기능을 제공하는 화장료 조성물 및 이를 이용한 제품의 필요성이 대두되고 있다.It is true that most cosmetics currently on the market can not support these demands. Therefore, by using finger root extract powder, it is possible to improve skin homeostasis by maintaining skin health from skin damage caused by ultraviolet rays, and it is possible to neutralize the toxicity of finger root extract, thereby ensuring safe, convenient, There is a need for a cosmetic composition that provides a complex skin homeostatic function such as skin soothing and skin moisturizing, and a product using the same.
본 발명자들은 천연재료를 이용한 복합기능성 화장품에 대한 시장의 요구가 높아짐에 따라 피부개선을 위해서는 다양한 피부 트러블 요인들이 서로 복합 상승작용을 하기 때문에 한가지 요인의 제어만으로는 피부건강을 효과적이고 안전하게 개선시키기 어렵다는 개념을 인식하여, 피부 항상성 유지가 가능한 성분 또는 조성을 찾는 것을 목표로 연구를 진행하였다. The present inventors have found that it is difficult to effectively and safely improve skin health by controlling only one factor because various skin trouble factors are combined and synergized with each other in order to improve the skin as the market demand for multi-functional cosmetics using natural materials increases. And to search for ingredients or compositions capable of maintaining skin homeostasis.
이러한 목표를 위하여 본 발명의 발명자들은 새로운 항노화, 항산화, 미백, 주름개선 효능을 나타내는 소재에 관하여 연구하던 중 2013년에 식품의약품안전처에서 건강기능식품의 기능성 원료로 인정되었으며 생리활성기능 2등급을 받은 판두라틴(Panduratin)에 주목하였다.For this purpose, the inventors of the present invention have been studying a new anti-aging, antioxidant, whitening and wrinkle-reducing material, and it was recognized as a functional ingredient of health functional food in the Food and Drug Administration in 2013, (Panduratin).
판두라틴은 핑거루트(Fingerroot, Boesenbergia pandurata)의 뿌리에서 추출한 기능성 원료로서, 판두라틴이 자외선에 의한 피부 손상으로부터 피부 건강을 유지하고 체내 에너지 항상성 유지를 위한 센서 단백질인 'AMPK(AMP-activated protein kinase)'를 활성화시켜 체지방을 감소하는 데 도움을 줄 수 있다고 판단하고, 판두라틴의 독성으로 인한 피부세포의 기능 저하 및 이로 인한 피부노화를 방지하고, 피부염증을 억제하는 한방식물 추출물과의 효과적인 배합방법을 밝혀내어 본 발명을 완성하였다.Pandur Latin is the Fingerroot ( Boesenbergia pandurata ), Panduratin activates AMP-activated protein kinase (AMPK), which maintains skin health and protects energy homeostasis from skin damage caused by ultraviolet rays, and reduces body fat The present invention has been accomplished on the basis of the finding that a method for effectively inhibiting skin inflammation by inhibiting skin cell function and deterioration of skin caused by toxicity of panduratin and effectively inhibiting skin inflammation .
따라서 본 발명의 목적은 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물을 제공하는데 있다.Accordingly, an object of the present invention is to provide a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant.
본 발명의 다른 목적은 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 제조방법을 제공하는데 있다.Another object of the present invention is to provide a method for producing a skin homeostatic non-toxic cosmetic composition containing ginger and plant extract.
본 발명의 다른 목적은 상기 피부 항상성 무독성 화장료 조성물을 함유하는 마스크팩을 제공하는데 있다.Another object of the present invention is to provide a mask pack containing the skin homeostatic non-toxic cosmetic composition.
본 발명의 다른 목적은 상기 피부 항상성 무독성 화장료 조성물을 함유하는 마스크팩의 제조방법을 제공하는데 있다.Another object of the present invention is to provide a method of manufacturing a mask pack containing the skin homeostatic non-toxic cosmetic composition.
상술한 목적을 달성하기 위해 본 발명은 핑거루트뿌리줄기추출물과, 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물을 함유하는 피부 항상성 무독성 화장료 조성물을 제공한다. In order to achieve the above-mentioned object, the present invention provides a method for producing a fungus root extract, which comprises extracting finger root rootstock, locust bean sprout extract, locust extract, mashin extract, bamboo extract, rice bran extract, mushroom extract, chamomile flower / leaf extract, mung bean extract, The present invention provides a skin homeostatic non-toxic cosmetic composition containing a leaf extract.
이때, 본 발명에 따른 상기 조성물은 100 중량%에 대하여, 정제수 40-50중량%, 상기 핑거루트뿌리줄기추출물 1-15중량% 및 상기 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물을 각각 0.1-5중량% 포함하는 것을 특징으로 한다.At this time, the composition according to the present invention comprises 40-50% by weight of purified water, 1-15% by weight of the finger root rootstock extract, and at least one extract selected from the group consisting of Centella asiatica extract, locust extract, mash extract, bamboo extract, , Mushroom extract, chamomile flower / leaf extract, mung bean extract, green tea extract and eucalyptus leaf extract, respectively, in an amount of 0.1-5% by weight.
또한, 본 발명에 따른 상기 조성물은 꿀추출물을 0.1-5중량% 더 포함하는 것을 특징으로 한다.Also, the composition according to the present invention is characterized by further containing 0.1 to 5% by weight of a honey extract.
상술한 다른 목적을 달성하기 위해 본 발명은 피부 항상성 무독성 화장료 조성물 제조방법을 제공한다.In order to achieve the above-mentioned other objects, the present invention provides a method for manufacturing a skin homeostatic non-toxic cosmetic composition.
상술한 다른 목적을 달성하기 위해 본 발명은 상기 피부 항상성 무독성 화장료 조성물을 포함하는 피부 항상성 무독성 마스크팩을 제공한다.In order to achieve the above-mentioned other objects, the present invention provides a skin homeostatic non-toxic mask pack comprising the skin homeostatic non-toxic cosmetic composition.
상술한 다른 목적을 달성하기 위해 본 발명은 상기 피부 항상성 무독성 화장료 조성물을 포함하는 피부 항상성 무독성 마스크팩의 제조방법을 제공한다.In order to achieve the above-mentioned other objects, the present invention provides a method for producing a skin homeostatic non-toxic mask pack comprising the skin homeostatic non-toxic cosmetic composition.
상기와 같이, 본 발명은 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 및 그 제조방법을 제공한다. 본 발명의 조성물은 항노화, 항산화, 미백 및 주름개선 효능이 있으며, 판두라틴의 독성으로 인한 피부세포의 기능 저하, 이로 인한 피부노화 및 피부염증을 방지하는 한방식물 추출물과의 효과적인 배합방법을 통해 무독성 활성 및 염증억제 활성이 우수하여 피부 항상성 제품 제조에 효과적이다.As described above, the present invention provides a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant, and a process for producing the same. The composition of the present invention is effective for anti-aging, antioxidant, whitening and anti-wrinkle effect, and effective combination with oriental plant extract which prevents skin cell dysfunction caused by toxicity of panduratin, skin aging and skin inflammation It has excellent non-toxic activity and anti-inflammatory activity and is effective for manufacturing skin home products.
도 1은 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 및 마스크팩 제조과정을 함께 도시한 도면,
도 2는 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 분화유도제를 처리하지 않은 세포에 대한 24시간 동안의 독성처리 결과를 나타낸 세포생사판별시험 그래프,
도 3은 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 분화기간 동안 세포에 대한 6일 동안의 독성처리 결과를 나타낸 세포생사판별시험 그래프.BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a view illustrating a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant according to the present invention,
FIG. 2 is a graph showing the results of a cytotoxicity test of the skin non-toxic cosmetic composition containing extracts of ginger and plants according to the present invention,
FIG. 3 is a graph showing a cytotoxicity test on a skin non-toxic cosmetic composition containing an extract of ginger and a plant according to the present invention, showing the results of toxicity treatment for 6 days on cells during the differentiation period.
이하 본 발명의 바람직한 실시 예들의 상세한 설명이 첨부된 도면들을 참조하여 설명될 것이다. 하기 설명에서 구체적인 특정 사항들이 나타나고 있는데, 이는 본 발명의 보다 전반적인 이해를 돕기 위해 제공된 것일 뿐, 본 발명을 특정한 실시 형태에 대해 한정하려는 것이 아니며, 본 발명의 사상 및 기술 범위에 포함되는 모든 변경, 균등물 내지 대체물을 포함하는 것으로 이해되어야 한다. 그리고 본 발명을 설명함에 있어, 관련된 공지 기능 혹은 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우 그 상세한 설명을 생략한다. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a detailed description of preferred embodiments of the present invention will be given with reference to the accompanying drawings. It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the invention. Accordingly, the invention in its broader aspects is not limited to the specific details and representative embodiments shown and described herein. Accordingly, It is to be understood that the invention includes equivalents and alternatives. In the following description of the present invention, detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.
다르게 정의되지 않는 한, 기술적이거나 과학적인 용어를 포함해서 여기서 사용되는 모든 용어들은 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자에 의해 일반적으로 이해되는 것과 동일한 의미를 가지고 있다. 일반적으로 사용되는 사전에 정의되어 있는 것과 같은 용어들은 관련 기술의 문맥상 가지는 의미와 일치하는 의미를 가진 것으로 해석되어야 하며, 본 출원에서 명백하게 정의하지 않는 한, 이상적이거나 과도하게 형식적인 의미로 해석되지 않는다. Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries should be interpreted as having a meaning consistent with the meaning in the context of the relevant art and are to be interpreted in an ideal or overly formal sense unless explicitly defined in the present application Do not.
본 발명의 상세한 설명에서 사용되는 "피부 케어" 또는 "피부 개선"이란 피부의 손상, 질환 증세를 억제 또는 지연시키거나, 질환 증세를 호전시키거나, 피부의 건강 상태를 향상시키는 모든 행위 또는 효과를 의미한다."Skin care" or "skin improvement ", as used in the detailed description of the present invention, refers to any action or effect that inhibits or slows skin damage, disease symptoms, improves disease symptoms, it means.
용어 "추출물(extract)"이란 천연물로부터 분리된 활성성분 즉, 목적하는 활성을 보이는 물질을 의미한다. 상기 추출물은 물, 유기용매 또는 이들의 혼합용매를 이용하는 추출 과정으로 획득할 수 있으며, 추출물 이의 건조 분말 또는 이를 이용하여 제형화된 모든 형태를 포함한다. 또한, 상기 추출물에는 상기 추출 과정을 거친 추출물을 분획한 것도 포함된다.The term "extract" means an active ingredient isolated from a natural product, i.e., a substance exhibiting the desired activity. The extract can be obtained by an extraction process using water, an organic solvent, or a mixed solvent thereof, and includes all the forms that are formulated with the dry powder of the extract. In addition, the above-mentioned extract also includes fractions obtained by fractionating the extract obtained through the above extraction process.
도 1은 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 및 마스크팩 제조과정을 함께 도시한 도면으로서, 도 1에 도시된 바와 같이 본 발명은 생강과 식물인 핑거루트의 뿌리 및 줄기 추출물과 한방식물 추출물을 유효성분으로 포함하는 피부 항상성 무독성 화장료 조성물과 그 조성물 제조과정 및 이를 이용한 마스크팩 제조과정을 제공한다. FIG. 1 is a view showing a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant according to the present invention and a process of manufacturing a mask pack. As shown in FIG. 1, the present invention includes a root of a finger root The present invention provides a skin homeostatic non-toxic cosmetic composition comprising stem extract and oriental plant extract as an active ingredient, a process for preparing the composition, and a process for producing a mask pack using the same.
본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물은 전체 100 중량%에 대하여, 정제수 40-50중량%, 상기 핑거루트뿌리줄기추출물 1-15중량% 및 상기 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물을 각각 0.1-5중량% 포함하여 제조된다.The skin homeostatic non-toxic cosmetic composition containing the extract of ginger and plant according to the present invention contains 40-50% by weight of purified water, 1-15% by weight of the finger root rootstock extract, and the centipede extract, And 0.1 to 5% by weight of the extracts of green tea, green tea, and eucalyptus leaf, respectively.
인체는 나이가 들면서 손상된 콜라겐을 대체하는 피부능력이 소멸하여 피부는 물론 뼈와 관절, 그리고 혈관과 머리카락까지 영향을 주게 되며, 모세혈관의 순환장애로 영양공급이 원활이 이루어지지 못하게 된다.As the body grows older, the ability to replace damaged collagen is extinguished, affecting the skin as well as the bones, joints, blood vessels and hair, and the circulation of the capillaries prevents the supply of nutrients.
따라서 콜라겐과 같은 단백질의 생산을 증가시키는 물질을 세포에 직접 공급해주고, 영양분을 공급해주는 모세혈관의 순환을 원활하게 해 준다면 피부개선 및 피부 항상성을 유지시킬 수 있다. Therefore, it is possible to supply skin cells directly with substances that increase the production of proteins such as collagen, and improve circulation of the capillaries that supply the nutrients, thereby improving the skin and maintaining the skin homeostasis.
본 발명의 조성물의 또 다른 유효성분인 한방식물 추출물을 구성하는 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물은 이러한 세포의 기능 저하에 의한 노화로 인해 파괴되는 콜라겐의 합성을 증가시키고, 혈액순환을 촉진시켜 노화를 방지하기 위한 것이다. The present invention relates to a composition for extracting oriental herbal medicine which is another active ingredient of the composition of the present invention, such as Centella asiatica extract, locust extract, marjoram extract, bamboo extract, rice bran extract, mushroom extract, chamomile flower / leaf extract, mung bean extract, green tea extract and eucalyptus leaf The extract is intended to increase the synthesis of collagen which is destroyed by the aging due to the dysfunction of such cells, and to prevent aging by promoting blood circulation.
또한, 상기 한방식물 추출물은 핑거루트뿌리줄기추출물에 소량 함유되어 있는 독성을 중화시켜 자극받은 피부를 편안하게 진정시켜주고, 사용 후 끈적임 없이 상쾌한 느낌을 제공한다. In addition, the herbal plant extract neutralizes toxicities contained in a small amount of finger root rootstock extract and calms the stimulated skin comfortably and provides a refreshing feeling after use.
이를 위하여, 본 발명에 따른 상기 조성물은 핑거루트뿌리줄기추출물에 소량 함유되어 있는 독성의 중화를 돕기 위하여 꿀추출물을 0.1-5중량% 더 포함하는 것이 바람직하다. To this end, the composition according to the present invention preferably contains 0.1 to 5% by weight of a honey extract to help neutralize toxicity contained in a small amount of Finger root rootstock extract.
상기 한방식물 추출물은 물, 탄소수 1 내지 4의 저급 알코올 또는 이들의 혼합 용매로부터 선택된 용매를 사용하여 추출되는 것이 바람직하며, 보다 바람직하게는 에탄올 또는 에탄올과 물의 혼합물이다. 상기 추출 용매의 적합한 양은 특별히 제한되지 아니하며, 한방식물을 구성하는 병풀, 위치하젤, 마치현, 대나무, 쌀겨, 상황버섯, 캐모마일꽃/잎, 녹두, 녹차 및 유칼립투스잎 중량의 1-10 배이며, 보다 바람직하게는 5-8배이다. 그러나 본 발명의 유효성분인 한방식물 추출물을 추출하는 방법은 특별히 제한되지 않는다. The herbal plant extract is preferably extracted using a solvent selected from water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, more preferably ethanol or a mixture of ethanol and water. The suitable amount of the extracting solvent is not particularly limited and is 1-10 times the leaf weight of the oriental herb, oriental jelly, marjoram, bamboo, rice bran, mushroom, chamomile flower / leaf, mung bean, green tea and eucalyptus leaf, Preferably 5-8 times. However, there is no particular limitation on the method for extracting the herbal plant extract as an active ingredient of the present invention.
한편, 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물에는 핑거루트뿌리줄기추출물 및 한방식물 이외에, 수분증발차단을 위해 올리브오일이 0.5-3중량%의 함량으로 첨가될 수 있으며, 컨디셔닝제로서 달팽이점액여과물이 전체 컨디셔닝제의 전체 함량 중 10-30중량%로 첨가될 수 있다. Meanwhile, in the skin homeostatic non-toxic cosmetic composition containing ginger and plant extract according to the present invention, olive oil may be added in an amount of 0.5-3% by weight in order to block moisture evaporation, in addition to finger root rootstock extract and Oriental herbaceous plant , And as a conditioning agent, snail mucus filtrate may be added in an amount of 10-30% by weight of the total amount of the conditioning agent.
본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 독성평가에 대한 결과 그래프를 도 2 및 도 3에 도시하였다. 도 2는 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 분화유도제를 처리하지 않은 세포에 대한 24시간 동안의 독성처리 결과를 나타낸 세포생사판별시험(Cell Viability) 그래프이고, 도 3은 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물의 분화기간 동안 세포에 대한 6일 동안의 독성처리 결과를 나타낸 세포생사판별시험 그래프이다.The results of the toxicity evaluation of the skin non-toxic cosmetic composition containing the extract of ginger and plant according to the present invention are shown in Figs. 2 and 3. FIG. 2 is a graph showing cell viability of a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant according to the present invention, showing the results of toxicity treatment for 24 hours on cells not treated with a differentiation inducing agent, FIG. 3 is a graph showing the results of toxicity of cells for 6 days during the differentiation period of a skin homeostatic non-toxic cosmetic composition containing an extract of ginger and a plant according to the present invention.
도 2 및 도 3의 효능평가 시험을 위하여, ATCC(American Type Culture Collection, Manassas, VA, USA)에서 구입한 인체 피부 진피 섬유아세포(Hs68 cell)를 10% FBS, penicillin (100 unit/ml), streptomycin (50 ㎍/ml) 배지에서, 37℃, 5% CO2, 95% humid air로 조절된 배양기에서 세포배양하여 사용하였다.Human skin dermal fibroblasts (Hs68 cells) purchased from ATCC (American Type Culture Collection, Manassas, VA, USA) were suspended in 10% FBS, penicillin (100 unit / ml) The cells were cultured in streptomycin (50 ㎍ / ml) medium at 37 ℃, 5% CO 2 , 95% humidified air.
도 2 및 도 3에 도시된 그래프는 인체 피부 섬유아세포를 1x104cells/well 농도로 96well plat에 분주하여 24시간 및 6일 동안 각각 배양한 후, 각 well에 본 발명에 따른 조성물 샘플을 투여하여 24시간 뒤 샘플의 독성을 살핀 세포생사판별시험 그래프이다.2 and 3, the human skin fibroblasts were divided into 96-well plats at a concentration of 1 × 10 4 cells / well and cultured for 24 hours and 6 days, respectively. Then, the composition sample according to the present invention was administered to each well After 24 hours, it is a graph of the cell lysate discrimination test which examines the toxicity of the sample.
상기 세포생사판별시험은 자외선 조사 후 세포 생존율을 평가하는 것으로, 배지에 섬유아세포를 seeding 후 24시간 및 6일 동안 각각 배양한 후 배지를 제거하여 PBS(Phosphate Buffer Saline)로 세척하고, PBS를 얇게 깐 후 UVB램프(Ultraviolet B lamp, Sankyo denki Lamps, GL20SE, Marine, Japan)로 30 mJ/㎠ 조사한다. UVB램프 조사 후 PBS로 세척하고 본 발명에 따른 조성물 샘플을 투여하여 24시간 배양시켜 세포생존율을 평가한 것이다. The cells were incubated for 24 hours and 6 days after seeding of fibroblasts. The medium was removed, and the cells were washed with phosphate buffered saline (PBS) After that, 30 mJ / ㎠ is irradiated with a UVB lamp (Ultraviolet B lamp, Sankyo Denki Lamps, GL20SE, Marine, Japan). After UVB lamp irradiation, the cells were washed with PBS, and a sample of the composition according to the present invention was administered, followed by incubation for 24 hours to evaluate cell viability.
섬유아세포를 24시간 및 6일 동안 각각 배양하고 자외선을 조사한 시료에 본 발명에 따른 조성물 샘플을 투여하여 24시간 배양 후 MTT 용액(1 mg/ml)을 첨가하고 4시간 동안 배양한 후, 배지를 제거하고 DMSO(DiMethyl SulfOxide)에 재용해 하여 550 nm에서 흡광도를 측정한 결과를 도 2 및 도 3에 각각 나타낸 것이다.The fibroblasts were cultured for 24 hours and 6 days, respectively, and the composition samples according to the present invention were administered to the ultraviolet irradiated samples. After culturing for 24 hours, MTT solution (1 mg / ml) was added and incubated for 4 hours. 2 and 3 show the results of absorbance measurement at 550 nm by re-dissolving in DMSO (DiMethyl Sulfoxide).
도 2 및 도 3에 도시된 바와 같이, 대조군인 케르세틴(Quercetin) 대비 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물을 투여한 섬유아세포는 24시간 및 6일 동안의 세포생존율이 높게 평가되었다. As shown in Figs. 2 and 3, the fibroblasts administered with the skin homeostatic non-toxic cosmetic composition containing the extract of ginger and plant according to the present invention as compared with the control group Quercetin showed a cell survival rate of 24 hours and 6 days Was highly evaluated.
전술한 세포생사판별시험 결과에 따라, 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물은 독성이 크게 개선되었음을 확인할 수 있다.According to the results of the above cell-cell differentiation test, it is confirmed that the skin homeostatic non-toxic cosmetic composition containing the extract of ginger and plant according to the invention has greatly improved toxicity.
이하, 도 1을 참조하여 본 발명에 따른 피부 항상성 무독성 화장료 조성물 제조방법 및 마스크팩의 제조방법을 상세히 설명한다. Hereinafter, a method for manufacturing a skin homeostatic non-toxic cosmetic composition and a method for manufacturing a mask pack according to the present invention will be described in detail with reference to FIG.
도 1에 도시된 바와 같이, 본 발명에 따른 피부 항상성 무독성 화장료 조성물은 전체 조성물 100중량%에 대하여 유화제 0.5-3중량%와, 착향제 0.05-1중량%를 제1혼합제(10)로 준비한 후, 제1용기에 투입하여, 용해, 분산 및 혼합한다(11단계). 여기서, 상기 유화제는 폴리소르베이트 80(Polysorbate 80)가 사용될 수 있고, 상기 착향제는 조합향료가 사용될 수 있다.As shown in FIG. 1, the skin homeostatic non-toxic cosmetic composition according to the present invention comprises 0.5-3% by weight of an emulsifier and 0.05-1% by weight of a flavoring agent as a first mixture (10) , And the resulting mixture is put into a first vessel to dissolve, disperse and mix (Step 11). Here, polysorbate 80 (Polysorbate 80) may be used as the emulsifier, and the flavoring agent may be a combination flavoring agent.
상기 제1혼합제(10)의 용해, 분산 및 혼합과 병행하여, 제2혼합제(20)를 용해, 분산 및 혼합한다(21단계).The
상기 제2혼합제(20)는 전체 100 중량%에 대하여, 정제수 40-50중량%, 상기 핑거루트뿌리줄기추출물 1-15중량% 및 상기 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물을 각각 0.1-5중량%를 제2용기에 투입하여 용해, 분산 및 혼합한다(21단계).Wherein the
이때, 꿀추출물 0.1-5중량%, 유화제 1-10중량%, 컨디셔닝제 10-25중량%, 피부보습제 1-10중량%, 수분증발차단제, 계면활성제 및 보존제를 각각 0.5-3중량%, 금속이온봉쇄제, 점증제 및 피부보호제를 각각 0.05-1중량%로 투입하여 해, 분산 및 혼합할 수 있다(21단계).In this case, it is preferable that 0.1 to 5 wt% of a honey extract, 1-10 wt% of an emulsifier, 10-25 wt% of a conditioning agent, 1-10 wt% of a skin moisturizer, 0.5-3 wt% of a surfactant and a preservative, The ionic blocking agent, the thickening agent and the skin protecting agent may be added in amounts of 0.05 to 1% by weight, respectively, and dispersed and mixed (Step 21).
여기서, 상기 유화제는 트리에탄올아민(Triethanolamine)과 프릴릭/카프릭트리글리세라이드(Caprylic/Capric Triglyceride)가 사용될 수 있고, 상기 컨디셔닝제로는 부틸렌글라이콜(ButyleneGlycol), 프로필렌글라이콜(PropyleneGlycol), 하이알루로닉애씨드(HyaluronicAcid), 달팽이점액여과물(SnailSecretionFiltrate), 아데노신(Adenosine), 나이아신아마이드(Niacinamide), 하이드롤라이즈드콜라겐(HydrolyzedCollagen), 알란토인(Allantoin)이 사용될 수 있으며, 상기 피부보습제로는 글리세린(Glycerin)이 사용될 수 있다.Examples of the emulsifier include triethanolamine and caprylic / capric triglyceride. Examples of the conditioning agent include butylene glycols, propylene glycol, It is possible to use Hyaluronic Acid, Snail Seecretion Filtrate, Adenosine, Niacinamide, Hydrolyzed Collagen, Allantoin and the like as the skin moisturizing agent Glycerin may be used.
또한, 상기 수분증발차단제로는 올리브오일(OleaEuropaea(Olive)FruitOil)이, 계면활성제로는 피이지-60하이드로제네이티드캐스터오일(PEG-60HydrogenatedCastorOil)이, 보존제로는 1,2-헥산디올(1,2-Hexanediol)이 사용될 수 있다. 상기 금속이온봉쇄제로는 디소듐이디티에이(DisodiumEDTA), 점증제로는 카보머(Carbomer) 및 피부보호제로는 옥타펩타이드(Octapeptide)가 사용될 수 있다.As the moisture evaporation blocking agent, olive oil (OleaEuropaea (Olive) FruitOil), surfactant (PEG-60 Hydrogenated Castor Oil) as a surfactant, 1,2-hexanediol (1 , 2-hexanediol) can be used. Disodium EDTA may be used as the metal ion sequestrant, Carbomer may be used as an increasing agent, and Octapeptide may be used as a skin protecting agent.
상기 11단계에서 혼합된 제1혼합제는 13단계에서 여과 및 제2용기로 이송되어, 상기 21단계에서 혼합된 제2혼합제와 혼합교반된다(23단계). 이때, 제1혼합제와 제2혼합제가 각각 여과이송되어 유화기 등에서 혼합교반될 수도 있다. The first mixture mixed in
상기 23단계에서 혼합교반된 혼합물은 탈포(25단계) 후, 여과 및 저장탱크로 이송(27단계)되어 저장되어 15~25시간의 숙성(29단계)과정을 거침으로써, 본 발명에 따른 피부 항상성 무독성 화장료 조성물의 제조가 완료된다.The mixture mixed and stirred in the
도 1의 30단계는 본 발명에 따른 피부 항상성 무독성 화장료 조성물을 이용한 제품의 제조방법을 도식화한 것이다. 먼저, 상기 29단계에서 숙성된 본 발명에 따른 조성물은 31단계에 이송되어, 33단계에서 투입된 용기에 충진된다(35단계). 그리고 37단계로 진행하여 충진된 용량을 체크하여 기 정해진 용량에 맞게 충진된 제품은 39단계의 실링(밀봉)을 거쳐 제조가 완료된다.FIG. 1 illustrates a method of manufacturing a product using the skin homeostatic non-toxic cosmetic composition according to the present invention. First, the composition according to the present invention aged in
본 발명에 따른 피부 항상성 무독성 화장료 조성물을 이용한 제품의 제조방법으로 제조된 제품은 마스크팩일 수 있다. The product manufactured by the method of manufacturing a product using the skin homeostatic non-toxic cosmetic composition according to the present invention may be a mask pack.
피부 트러블의 원천적 요인들 즉, 호르몬 불균형, 모낭 안 박테리아균, 생활습관에 따른 다양한 스트레스와 불규칙한 식습관과 관련된 요인, 피지선의 민감도, 위생 상태에 의한 2차적 유해균 발생, 염증반응, 산화스트레스 등의 요인이 증가하게 되면, 이 들의 작용이 더욱 복합적으로 작용하여 알러지반응, 혈액순환 부진, 세포 대사 및 생장 억제 작용이 나타난다. 그리고 이러한 원인들에 의해 결국, 가려움, 염증 등 피부 트러블 현상이 발생된다.Factors such as hormonal imbalance, hair follicle bacteria, various stresses related to lifestyle, irregular eating habits, sensitivity of sebaceous glands, secondary harmful bacteria caused by hygiene, inflammation reaction, oxidative stress , The action of these compounds is more complex, resulting in allergic reactions, poor blood circulation, inhibition of cell metabolism and growth. These causes ultimately cause skin troubles such as itching and inflammation.
상기한 2차적 요인 중 하나인 염증반응은 유해균의 자극에 의해서 발생하며, 이와 관계없이 고칼로리와 운동부족으로 특징화 되는 서구화된 생활습관에 의한 대사성증후군에 의해서도 만성적으로 발생하며, 정신적인 스트레스나 쇼크에 의해 일시적으로 발생할 수도 있다. 염증반응은 조직의 퇴행화를 가속화 시키고, 세포생장을 억제하며, 면역체계를 과도하게 민감하게 함으로써 알러지 현상을 더욱 자극하는 등, 피부 조직의 건강을 해치게 된다. Inflammatory reactions, one of the secondary factors mentioned above, are caused by the stimulation of harmful bacteria. Regardless of this, chronic metabolic syndrome caused by westernized living habits characterized by high calorie and lack of exercise is chronic, and mental stress It may occur temporarily by shock. Inflammation reactions impair the health of skin tissue, such as accelerating tissue degeneration, inhibiting cell growth, and over-sensitizing the immune system, further stimulating the allergic phenomenon.
상기한 요인들(유해균, 염증, 산화스트레스)은 서로 복합적으로 상승 작용하여 지속되고 더욱 심해지는 악순환을 초래함으로써 피부 트러블을 일으킨다. 따라서 상기와 같은 복합적인 요인들에 대하여 모두 우수한 효과를 제공하는 본 발명의 조성물은 살균작용에 의한 피부개선, 피부진정, 피부보습을 비롯하여 세포의 기능 저하로 인해 파괴되는 콜라겐의 합성을 증가시키고, 혈액순환을 촉진시켜 노화를 방지하는 등 피부 항상성을 유지하는데 매우 우수한 효과를 제공한다. The above-mentioned factors (harmful bacteria, inflammation, oxidative stress) cause a skin trouble by causing a vicious circle which continues to multiply and continue to multiply with each other. Therefore, the composition of the present invention, which provides excellent effects to all of the above-mentioned complex factors, increases the synthesis of collagen which is destroyed due to cell function, including skin improvement, skin soothing, skin moisturization, It promotes circulation of blood to prevent aging and provides excellent effect for maintaining skin homeostasis.
또한, 기존의 판두라틴을 유효성분으로 하는 화장료 조성물은 독성 및 자극성으로 인하여 피부에 머무르는 시간을 최소화 해야 하며, 내성도 발생시키는 문제가 있으나, 본 발명의 조성물은 독성 및 자극성이 없으므로, 안전하고 간편하게 피부 항상성을 유지시킬 수 있다. In addition, the conventional cosmetic composition containing panduratin as an active ingredient has a problem of minimizing the time for staying on the skin due to toxicity and irritation, and also causing resistance. However, since the composition of the present invention has no toxicity and irritation, Skin homeostasis can be maintained.
상술한 바와 같이, 본 발명에 따른 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물은 자외선에 의해 발현이 감소된 유전자의 발현을 정상화시킴으로써 피부세포의 항상성을 유지하고 생강과 식물의 독성을 제거함으로써 안전한 기능성 화장품 제조에 효과적으로 사용될 수 있다. As described above, the skin homeostatic non-toxic cosmetic composition containing the extract of ginger and plant according to the present invention normalizes the expression of genes whose expression is reduced by ultraviolet rays, thereby maintaining the homeostasis of skin cells and eliminating the toxicity of ginger and plants And thus can be effectively used for manufacturing safe functional cosmetics.
본 발명의 화장료 조성물은 당업계에서 통상적으로 제조되는 어떠한 제형으로도 제조될 수 있으며, 본 발명의 한방식물 추출물 이외에도 피부과학적으로 허용 가능한 매질 또는 기제를 함유함으로써 피부과학 분야에서 통상적으로 사용되는 국소적용 또는 전신 적용할 수 있는 보조제 형태로 제조될 수 있다.The cosmetic composition of the present invention can be prepared into any formulation conventionally produced in the art. In addition to the herbal plant extract of the present invention, the cosmetic composition of the present invention can be used as a topical application Or may be formulated in the form of adjuvants which can be applied systemically.
적합한 화장료 조성물의 제형으로는 예를 들면 용액, 겔, 고체 또는 반죽 무수 생성물, 수상에 유상을 분산시켜 얻은 에멀젼, 현탁액, 마이크로에멀젼, 마이크로캡슐, 미세과립구 또는 이온형(리포좀), 비이온형의 소낭 분산제의 형태, 크림, 스킨, 로션, 파우더, 연고, 스프레이 또는 콘실 스틱(conceal stick)의 형태로 제공될 수 있다. 또한, 포말(foam)의 형태 또는 압축된 추진제를 더 함유한 에어로졸 조성물의 형태로도 제조될 수 있다.Formulations of suitable cosmetic compositions include, for example, solutions, gels, solid or paste anhydrous products, emulsions obtained by dispersing the oil phase in water, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) In the form of a foliar dispersant, in the form of a cream, a skin, a lotion, a powder, an ointment, a spray or a conceal stick. It can also be prepared in the form of a foam or an aerosol composition further containing a compressed propellant.
본 발명의 화장료 조성물을 첨가할 수 있는 제품으로는 이에 한정되는 것은 아니나, 마스크팩, 스킨로션, 스킨 소프너, 스킨토너, 스프레이, 수렴화장수, 유연화장수, 영양화장수, 아스트린젠트, 로션, 밀크로션, 모이스처 로션, 영양로션, 바디크림, 마사지크림, 영양크림, 마사지 크림, 모이스처 크림, 핸드크림, 에센스, 아이크림, 영양에센스, 팩, 비누, 샴푸, 클렌징폼, 클렌징로션, 클렌징크림, 바디로션, 바디클렌저, 트리트먼트, 미용액, 유액, 프레스파우더, 루스파우더, 아이섀도 등의 제형을 포함한다.Examples of the cosmetic composition to which the cosmetic composition of the present invention can be added include, but are not limited to, a mask pack, a skin lotion, a skin softener, a skin toner, a spray, a convergent lotion, a softening longevity, a nutritional lotion, an astringent, Lotion, Nutrition Lotion, Body Cream, Massage Cream, Nourishing Cream, Massage Cream, Moisture Cream, Hand Cream, Essence, Eye Cream, Nutrition Essence, Pack, Soap, Shampoo, Cleansing Foam, Cleansing Lotion, Cleansing Cream, Body Lotion, Body Cleanser, treatment, serum, emulsion, press powder, loose powder, eye shadow, and the like.
전술한 바와 같이, 본 발명의 조성물은 항노화, 항산화, 미백, 주름개선 효과 및 판두라틴의 독성으로 인한 피부세포의 기능 저하 및 이로 인한 피부노화를 방지하고, 피부염증을 억제하는 효과가 우수하며, 본 발명의 조성물 제조방법은 핑거루트뿌리줄기추출물 및 한방식물 추출물과의 효과적인 배합방법을 제공함으로써 전술한 우수한 효과를 갖는 조성물을 제공함을 확인하였다.As described above, the composition of the present invention is effective in preventing deterioration of skin cells due to antioxidation, antioxidation, whitening, wrinkle-reducing effect and toxicity of panduratin and skin aging caused thereby, , It was confirmed that the composition of the present invention provides a composition having the above-mentioned excellent effects by providing an effective combination method with Finger root root extract and Oriental plant extract.
한편 본 발명의 상세한 설명에서는 구체적인 실시 예에 관해 설명하였으나, 본 발명의 범위에서 벗어나지 않는 한도 내에서 여러 가지 변형이 가능함은 물론이다. 그러므로 본 발명의 범위는 설명된 실시 예에 국한되어 정해져서는 안되며 후술하는 특허청구의 범위뿐 아니라 이 특허청구의 범위와 균등한 것들에 의해서 정해져야 한다.While the present invention has been described in connection with what is presently considered to be the most practical and preferred embodiment, it is to be understood that the invention is not limited to the disclosed embodiments, but is capable of various modifications within the scope of the invention. Therefore, the scope of the present invention should not be limited by the described embodiments, but should be determined by the scope of the appended claims and equivalents thereof.
이상 살펴본 바와 같이, 본 발명은 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 및 그 제조방법을 제공하며, 본 발명의 조성물은 항산화, 무독성 활성 및 염증억제 활성이 우수하여 피부 항상성 제품 제조에 효과적이어서 산업상 이용가능성이 높다.INDUSTRIAL APPLICABILITY As described above, the present invention provides a skin homeostatic non-toxic cosmetic composition containing ginger and plant extracts and a method of preparing the same. The composition of the present invention is excellent in antioxidant, non-toxic activity and anti- It is effective and is highly likely to be used industrially.
Claims (6)
Skin homeostatic non-toxic cosmetic composition containing finger root rootstock extract and centilla mushroom extract, chamomile flower / leaf extract, mung bean extract, green tea extract and eucalyptus leaf extract, locust bean extract, locust lotus extract, marjoram extract, bamboo extract, rice bran extract, .
조성물 100 중량%에 대하여, 정제수 40-50중량%, 상기 핑거루트뿌리줄기추출물 1-15중량% 및 상기 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물을 각각 0.1-5중량% 포함하는 것을 특징으로 하는 조성물.
The method according to claim 1,
Wherein said extract is at least one selected from the group consisting of purified water at a concentration of from 40 to 50% by weight, purified water at a concentration of from 1 to 15% by weight of the finger root rootstock extract, and at least one selected from the group consisting of the centistallium extract, locust extract, mash extract, bamboo extract, Leaf extract, green mung bean extract, green tea extract and eucalyptus leaf extract, respectively, 0.1-5% by weight.
상기 조성물에 꿀추출물 0.1-5중량%를 더 포함하는 것을 특징으로 하는 조성물.
3. The method of claim 2,
Wherein the composition further comprises from 0.1 to 5% by weight of a honey extract.
A mask pack comprising the skin homeostatic composition of claim 1.
최종 조성물 100중량%에 대하여, 정제수 40-50중량%, 상기 핑거루트뿌리줄기추출물 1-15중량%, 상기 병풀추출물, 위치하젤추출물, 마치현추출물, 대나무추출물, 쌀겨추출물, 상황버섯추출물, 캐모마일꽃/잎추출물, 녹두추출물, 녹차추출물 및 유칼립투스잎추출물 각각 0.1-5중량%로 이루어지는 제2혼합제를 용해, 분산 및 혼합하는 제2공정;
상기 제1혼합제 및 제2혼합제를 각각 여과이송하여 하나의 용기에 혼합교반하는 제3공정;
상기 제3공정에서 혼합교반된 혼합물을 탈포하는 제4공정; 및
상기 제4공정에서 탈포된 혼합물을 여과 및 이송하여 15-25시간 동안 숙성시키는 제5공정;으로 이루어지는 것을 특징으로 하는 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 제조방법.
A first step of dissolving, dispersing and mixing a first mixture consisting of 0.5-3% by weight of an emulsifier and 0.05-1% by weight of a flavoring agent based on 100% by weight of the final composition;
The composition of the present invention comprises 40-50% by weight of purified water, 1-15% by weight of the finger root rootstock extract, 1-100% by weight of the centistallium extract, locust extract, mash extract, bamboo extract, rice bran extract, A second step of dissolving, dispersing and mixing a second mixture consisting of leaf extract, green bean extract, green tea extract and eucalyptus leaf extract in an amount of 0.1-5% by weight;
A third step in which the first mixture and the second mixture are respectively filtered and mixed and mixed and stirred in one container;
A fourth step of defoaming the mixed and stirred mixture in the third step; And
And a fifth step of filtering and transferring the defoamed mixture in the fourth step for aging for 15 to 25 hours. The method of manufacturing a skin homeostatic non-toxic cosmetic composition comprising the extract of ginger and plant.
최종 조성물 100중량%에 대하여, 꿀추출물 0.1-5중량%, 유화제 1-10중량%, 컨디셔닝제 10-25중량%, 피부보습제 1-10중량%, 수분증발차단제, 계면활성제 및 보존제를 각각 0.5-3중량%, 금속이온봉쇄제, 점증제 및 피부보호제를 각각 0.05-1중량% 더 포함하는 것을 특징으로 하는 생강과 식물의 추출물을 함유하는 피부 항상성 무독성 화장료 조성물 제조방법.6. The method of claim 5,
0.1 to 5% by weight of an extract of a honey, 1-10% by weight of an emulsifier, 10-25% by weight of a conditioning agent, 1-10% by weight of a skin moisturizer, a water evaporation blocking agent, a surfactant and a preservative in an amount of 0.5 -3 weight%, a sequestering agent, a thickening agent, and a skin protecting agent, respectively, in an amount of 0.05 to 1 wt%, based on the total weight of the composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160147269A KR20180050798A (en) | 2016-11-07 | 2016-11-07 | Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160147269A KR20180050798A (en) | 2016-11-07 | 2016-11-07 | Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180050798A true KR20180050798A (en) | 2018-05-16 |
Family
ID=62452141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020160147269A KR20180050798A (en) | 2016-11-07 | 2016-11-07 | Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR20180050798A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210021747A (en) | 2019-08-19 | 2021-03-02 | 이호규 | Method for extracting Boesenbergia pandurate extracts and cosmetic compositions containing the Boesenbergia pandurate extracts for skin elasticity and manufacturing method thereof |
| WO2023120763A1 (en) * | 2021-12-21 | 2023-06-29 | 이호규 | Emulsion-type skin elasticity improving cosmetic material using skin elasticity component material of naturally-derived plant fingerroot, preparation method therefor, and emulsion-type skin elasticity improving cosmetics |
-
2016
- 2016-11-07 KR KR1020160147269A patent/KR20180050798A/en not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210021747A (en) | 2019-08-19 | 2021-03-02 | 이호규 | Method for extracting Boesenbergia pandurate extracts and cosmetic compositions containing the Boesenbergia pandurate extracts for skin elasticity and manufacturing method thereof |
| WO2023120763A1 (en) * | 2021-12-21 | 2023-06-29 | 이호규 | Emulsion-type skin elasticity improving cosmetic material using skin elasticity component material of naturally-derived plant fingerroot, preparation method therefor, and emulsion-type skin elasticity improving cosmetics |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101146206B1 (en) | Cosmetic Composition And Composition of Skin External Application | |
| KR101387308B1 (en) | Skin whitening composition by using of dendropanax morbifera ferment extract | |
| KR102113193B1 (en) | Composition for improving skin conditions comprising artemisiae annuae herba, centella asiatica and green tea extract or fraction thereof and method for improving skin conditions using the same | |
| US20220287956A1 (en) | Composition containing cirsium japonicum extract as active ingredient for stimulating melanogenesis | |
| KR100633380B1 (en) | Compositions of oriental cosmetics for atopy skin containing mixture of specific herbal extracts | |
| KR20150105091A (en) | Cosmetic composition using fermented plant and manufacturing method thereof and hair shampoo | |
| AU2022275765A1 (en) | Antimicrobial skincare composition and treatment | |
| KR102300581B1 (en) | Compositions for improving skin conditions comprising plant extracts or fractions thereof | |
| KR20120009554A (en) | Cosmetic composition comprising mixed herbal extracts having anti-oxidant activity and anti-allergic activity | |
| KR101033921B1 (en) | Composition for reducing irritation and inflammation in skin | |
| KR102214985B1 (en) | Compositions for improving skin conditions comprising plant extracts or fractions thereof | |
| KR102169463B1 (en) | Cosmetic composition for improving skin troubles | |
| KR20190064714A (en) | Anti-inflammatory agent containing backhousia citriodora extract | |
| KR20180050798A (en) | Cosmetic compositions containing Zingiberaceae extracts for skin homeostasis and nontoxicity and manufacturing method thereof | |
| JP2020502172A (en) | Cosmetic composition containing Chinese herbal extract as active ingredient | |
| KR20200134929A (en) | Cosmetic composition containing complex medicinal herbs extract for skin whitening and anti-wrinkle effect and manufacturing method thereof | |
| KR101501538B1 (en) | Composition for External Application to the Skin Using an Extract of Seeds of Opuntia ficus-indica var. saboten | |
| KR20190049067A (en) | A cosmetic composition comprising extract of coffee silver skin and coffee grounds | |
| KR20170137436A (en) | Composition for improving skin condition comprising herb extracts mixture | |
| KR100946584B1 (en) | Cosmetic Composition Comprising Poncirus trifoliata fruit extract and Nymphaea caerulea extract | |
| KR20210048021A (en) | Antibacterial compositions comprising the citrus aurantium sinensis peel extract, the magnolia officinalis bark extract and polylysine | |
| JP2007045734A (en) | External preparation for skin and hyaluronidase inhibitor | |
| KR102208482B1 (en) | Cosmetic composition for improving skin troubles | |
| KR102650364B1 (en) | Composition for anti-oxidation, anti-inflammation, anti-atopy, anti-wrinkle and improvement of moisturizing comprising extract of Lycorisradiata | |
| KR102334192B1 (en) | Functional cosmetic composition comprising korean dandelion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| E902 | Notification of reason for refusal |