KR20170141215A - 싱글-암 유형 i과 유형 ii 수용체 융합 단백질들 및 이들의 용도 - Google Patents

싱글-암 유형 i과 유형 ii 수용체 융합 단백질들 및 이들의 용도 Download PDF

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KR20170141215A
KR20170141215A KR1020177031992A KR20177031992A KR20170141215A KR 20170141215 A KR20170141215 A KR 20170141215A KR 1020177031992 A KR1020177031992 A KR 1020177031992A KR 20177031992 A KR20177031992 A KR 20177031992A KR 20170141215 A KR20170141215 A KR 20170141215A
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seq
polypeptide
amino acid
type
tgf
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Ceased
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Korean (ko)
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라빈드라 쿠마르
아시야 그린베르그
다이안 에스. 사코
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악셀레론 파마 인코포레이티드
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Publication of KR20170141215A publication Critical patent/KR20170141215A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020177031992A 2015-04-06 2016-04-06 싱글-암 유형 i과 유형 ii 수용체 융합 단백질들 및 이들의 용도 Ceased KR20170141215A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562143579P 2015-04-06 2015-04-06
US62/143,579 2015-04-06
US201562259422P 2015-11-24 2015-11-24
US62/259,422 2015-11-24
PCT/US2016/026275 WO2016164501A1 (en) 2015-04-06 2016-04-06 Single-arm type i and type ii receptor fusion proteins and uses thereof

Publications (1)

Publication Number Publication Date
KR20170141215A true KR20170141215A (ko) 2017-12-22

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KR1020177031992A Ceased KR20170141215A (ko) 2015-04-06 2016-04-06 싱글-암 유형 i과 유형 ii 수용체 융합 단백질들 및 이들의 용도

Country Status (21)

Country Link
US (3) US10358476B2 (https=)
EP (2) EP3280727B1 (https=)
JP (2) JP6810702B2 (https=)
KR (1) KR20170141215A (https=)
CN (3) CN113683708A (https=)
AU (2) AU2016246602B2 (https=)
CA (1) CA2981793A1 (https=)
CY (1) CY1124247T1 (https=)
DK (1) DK3280727T3 (https=)
ES (1) ES2864850T3 (https=)
HR (1) HRP20210411T1 (https=)
HU (1) HUE054180T2 (https=)
LT (1) LT3280727T (https=)
MA (1) MA53883A (https=)
MD (1) MD3280727T2 (https=)
PL (1) PL3280727T3 (https=)
PT (1) PT3280727T (https=)
RS (1) RS61728B1 (https=)
SI (1) SI3280727T1 (https=)
SM (1) SMT202100246T1 (https=)
WO (1) WO2016164501A1 (https=)

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US20220315642A1 (en) 2022-10-06
JP2018517664A (ja) 2018-07-05
MA53883A (fr) 2021-08-18
AU2016246602B2 (en) 2020-11-19
AU2021200906A1 (en) 2021-03-04
MD3280727T2 (ro) 2021-06-30
PT3280727T (pt) 2021-04-23
SMT202100246T1 (it) 2021-05-07
EP3865505A1 (en) 2021-08-18
WO2016164501A1 (en) 2016-10-13
US10358476B2 (en) 2019-07-23
LT3280727T (lt) 2021-04-12
US12338273B2 (en) 2025-06-24
HUE054180T2 (hu) 2021-08-30
HRP20210411T1 (hr) 2021-04-30
HK1252958A1 (zh) 2019-06-06
CN107849114A (zh) 2018-03-27
DK3280727T3 (da) 2021-03-15
CN113683709A (zh) 2021-11-23
JP7203807B2 (ja) 2023-01-13
RS61728B1 (sr) 2021-05-31
CN113683708A (zh) 2021-11-23
ES2864850T3 (es) 2021-10-14
EP3280727A1 (en) 2018-02-14
US20200055920A1 (en) 2020-02-20
CY1124247T1 (el) 2022-07-22
SI3280727T1 (sl) 2021-07-30
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US20160289298A1 (en) 2016-10-06
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JP6810702B2 (ja) 2021-01-06
CN107849114B (zh) 2021-08-20
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