KR20170084086A - 오나프리스톤 연장-방출 조성물 및 방법 - Google Patents

오나프리스톤 연장-방출 조성물 및 방법 Download PDF

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Publication number
KR20170084086A
KR20170084086A KR1020177012909A KR20177012909A KR20170084086A KR 20170084086 A KR20170084086 A KR 20170084086A KR 1020177012909 A KR1020177012909 A KR 1020177012909A KR 20177012909 A KR20177012909 A KR 20177012909A KR 20170084086 A KR20170084086 A KR 20170084086A
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KR
South Korea
Prior art keywords
pharmaceutical composition
extended release
onapristone
formulation
day
Prior art date
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Ceased
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KR1020177012909A
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English (en)
Korean (ko)
Inventor
알렉산더 주키브스키
스테판 프로니크
Original Assignee
아르노 테라퓨틱스 인코포레이티드
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Publication of KR20170084086A publication Critical patent/KR20170084086A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020177012909A 2014-11-17 2015-11-16 오나프리스톤 연장-방출 조성물 및 방법 Ceased KR20170084086A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462080868P 2014-11-17 2014-11-17
US62/080,868 2014-11-17
PCT/US2015/060940 WO2016081383A1 (en) 2014-11-17 2015-11-16 Onapristone extended-release compositions and methods

Publications (1)

Publication Number Publication Date
KR20170084086A true KR20170084086A (ko) 2017-07-19

Family

ID=56014429

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177012909A Ceased KR20170084086A (ko) 2014-11-17 2015-11-16 오나프리스톤 연장-방출 조성물 및 방법

Country Status (11)

Country Link
US (3) US10786461B2 (OSRAM)
EP (1) EP3247362A4 (OSRAM)
JP (1) JP6655075B2 (OSRAM)
KR (1) KR20170084086A (OSRAM)
CN (2) CN106999501B (OSRAM)
AU (2) AU2015350241B2 (OSRAM)
CA (1) CA2966753A1 (OSRAM)
HK (1) HK1246653A1 (OSRAM)
MX (1) MX391191B (OSRAM)
RU (1) RU2017112748A (OSRAM)
WO (1) WO2016081383A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CA3008422A1 (en) 2015-12-15 2017-06-22 Context Biopharma Inc. Amorphous onapristone compositions and methods of making the same
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

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Also Published As

Publication number Publication date
EP3247362A4 (en) 2018-10-10
AU2015350241B2 (en) 2021-05-20
CA2966753A1 (en) 2016-05-26
US20210220279A1 (en) 2021-07-22
CN106999501B (zh) 2021-08-13
EP3247362A1 (en) 2017-11-29
MX391191B (es) 2025-03-21
CN106999501A (zh) 2017-08-01
RU2017112748A3 (OSRAM) 2019-06-26
US20160166583A1 (en) 2016-06-16
RU2017112748A (ru) 2018-12-19
JP2017537883A (ja) 2017-12-21
US11672762B2 (en) 2023-06-13
WO2016081383A1 (en) 2016-05-26
HK1246653A1 (zh) 2018-09-14
AU2015350241A1 (en) 2017-05-04
CN113559075A (zh) 2021-10-29
US20230157960A1 (en) 2023-05-25
US10786461B2 (en) 2020-09-29
JP6655075B2 (ja) 2020-02-26
MX2017005163A (es) 2018-01-18
AU2021218093A1 (en) 2021-09-09

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