KR20170054459A - 친수성 약물의 표적 전달 방법 - Google Patents
친수성 약물의 표적 전달 방법 Download PDFInfo
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- KR20170054459A KR20170054459A KR1020177009510A KR20177009510A KR20170054459A KR 20170054459 A KR20170054459 A KR 20170054459A KR 1020177009510 A KR1020177009510 A KR 1020177009510A KR 20177009510 A KR20177009510 A KR 20177009510A KR 20170054459 A KR20170054459 A KR 20170054459A
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- Prior art keywords
- straight chain
- sulfonate
- chain alkyl
- amphipathic
- sulfate
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1400427-9 | 2014-09-10 | ||
| SE1400427 | 2014-09-10 | ||
| PCT/SE2015/000055 WO2016039678A1 (en) | 2014-09-10 | 2015-09-09 | Targeted delivery of hydrophilic drugs |
Publications (1)
| Publication Number | Publication Date |
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| KR20170054459A true KR20170054459A (ko) | 2017-05-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020177009510A Withdrawn KR20170054459A (ko) | 2014-09-10 | 2015-09-09 | 친수성 약물의 표적 전달 방법 |
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| Country | Link |
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| EP (1) | EP3191138B1 (enExample) |
| JP (1) | JP6951971B2 (enExample) |
| KR (1) | KR20170054459A (enExample) |
| CN (1) | CN107073129B (enExample) |
| AU (1) | AU2015316252A1 (enExample) |
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| MX (1) | MX2017003049A (enExample) |
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| EP3426228A1 (en) * | 2016-03-07 | 2019-01-16 | Double Bond Pharmaceutical AB | Targeted delivery of hydrophilic drugs to lung |
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| WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
| CA2324254C (en) * | 1998-03-18 | 2005-01-04 | University Technology Corporation | Sustained-release composition including amorphous polymer |
| US6613358B2 (en) * | 1998-03-18 | 2003-09-02 | Theodore W. Randolph | Sustained-release composition including amorphous polymer |
| US6384081B2 (en) * | 1998-10-09 | 2002-05-07 | Charles L. Berman | Treatment of diseases of the eye characterized by the formation of metalloproteinase |
| CN101134119A (zh) | 2002-05-24 | 2008-03-05 | 血管技术国际股份公司 | 用于涂覆医用植入物的组合物和方法 |
| US8313760B2 (en) | 2002-05-24 | 2012-11-20 | Angiotech International Ag | Compositions and methods for coating medical implants |
| US20040161466A1 (en) | 2003-02-14 | 2004-08-19 | Biocompatibles Uk Limited | Chemoembolisation |
| GB2415904B (en) | 2005-02-07 | 2006-10-25 | Chiron Corp | Preparing aldesleukin for pharmaceutical use |
| WO2009078756A1 (en) | 2007-12-19 | 2009-06-25 | Ardenia Investments, Ltd. | Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance |
| WO2009100222A1 (en) | 2008-02-08 | 2009-08-13 | Qps Llc | Non-polymeric compositions for controlled drug delivery |
| CN101327190B (zh) * | 2008-07-29 | 2011-04-27 | 北京大学 | 一种供注射用的抗肿瘤长循环靶向脂质体 |
| KR101576174B1 (ko) * | 2010-07-26 | 2015-12-09 | 르 라보레또레 쎄르비에르 | 간암 요법을 위한 방법 및 조성물 |
| KR101728011B1 (ko) | 2013-01-23 | 2017-04-20 | 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 | 덱스트란 메타크릴레이트 및 생체적합성 음이온성 고분자를 포함하는 생분해성 마이크로 비드 및 이의 제조방법 |
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2015
- 2015-09-09 KR KR1020177009510A patent/KR20170054459A/ko not_active Withdrawn
- 2015-09-09 AU AU2015316252A patent/AU2015316252A1/en not_active Abandoned
- 2015-09-09 EA EA201790272A patent/EA033526B1/ru not_active IP Right Cessation
- 2015-09-09 US US15/509,875 patent/US10034838B2/en active Active
- 2015-09-09 MX MX2017003049A patent/MX2017003049A/es unknown
- 2015-09-09 CN CN201580048892.5A patent/CN107073129B/zh active Active
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2017
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2018
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3191138A4 (en) | 2018-06-20 |
| IL250637A0 (en) | 2017-04-30 |
| JP2017527593A (ja) | 2017-09-21 |
| JP6951971B2 (ja) | 2021-10-20 |
| EP3191138A1 (en) | 2017-07-19 |
| CA2958820A1 (en) | 2016-03-17 |
| EP3191138B1 (en) | 2024-05-29 |
| EA033526B1 (ru) | 2019-10-31 |
| US10034838B2 (en) | 2018-07-31 |
| MX2017003049A (es) | 2017-05-23 |
| WO2016039678A1 (en) | 2016-03-17 |
| US20170239192A1 (en) | 2017-08-24 |
| US20190046462A1 (en) | 2019-02-14 |
| EP3191138C0 (en) | 2024-05-29 |
| CN107073129A (zh) | 2017-08-18 |
| CN107073129B (zh) | 2021-10-15 |
| AU2015316252A1 (en) | 2017-03-09 |
| US10973772B2 (en) | 2021-04-13 |
| EA201790272A1 (ru) | 2017-07-31 |
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