KR20170041149A

KR20170041149A - Composition for improving atopic skin

Info

Publication number: KR20170041149A
Application number: KR1020160128424A
Authority: KR
Inventors: 최용호
Original assignee: 최용호
Priority date: 2015-10-06
Filing date: 2016-10-05
Publication date: 2017-04-14

Abstract

Disclosed is a composition for improving atopic skin. To achieve the objectives, the composition for improving the atopic skin contains an Aronia extract to decompose enzymes, Orosrachys malacophyllus extract, and further oak pyroligneous liquid, which has been matured for 6 years or more, wherein the content of the Aronia extract to decompose enzymes is 40-60 wt%, and the content of the Orosrachys malacophyllus extract is 40-60 wt%.

Description

TECHNICAL FIELD The present invention relates to a composition for improving atopic skin,

TECHNICAL FIELD The present invention relates to a composition for improving atopic skin, and more particularly to a composition for improving atopic skin comprising an enzyme decomposed extract and an extract of Wakoshi as an active ingredient.

Atopy refers to a series of allergic symptoms that appear in the skin, respiratory mucosa, mucous membranes, intestinal mucosa, and the like in individuals with atopy inducing factors. People with atopy inducers often show urticaria in skin reactions to protein substances that frequently come in contact with the outside environment, such as house dust mite, ticks, animal hair, food, pollen, mold, etc. When eating or inhaling certain protein substances Itching, skin seizures, angioedema, sneezing, runny nose, nasal congestion, conjunctival hyperemia, and septicemia.

Allergic diseases caused by atopy inducers include atopic dermatitis, allergic rhinitis, asthma, allergic conjunctivitis, allergic intestinal inflammation, and atopic allergies. These diseases are classified according to genetic predisposition, Or multiple diseases may occur at the same time.

In recent years, the incidence of atopic dermatitis has increased in all ages. This is due to the increase of exposure to antigens due to changes in air pollution, residential environment, decreased breastfeeding, Respectively.

Meanwhile, steroids and antihistamines, which are used as therapeutic agents for atopic dermatitis, have the effect of temporarily alleviating the symptoms. However, in the long-term use of external or oral steroid hormones, And the growth of children is inhibited by local and systemic side effects.

Therefore, there is a need to develop a therapeutic agent having excellent efficacy without such side effects.

Korean Laid-Open Patent No. 2013-0073512 (Mar.

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made in view of the above problems, and an object of the present invention is to provide a composition for improving atopic skin, which comprises a mixed extract containing an enzyme decomposed extract and an extract.

It is another object of the present invention to provide a composition for improving atopic skin in which an oak vinegar solution aged for 6 years or more is further added to a mixed extract.

In order to attain the above object, the composition for improving atopic skin according to the present invention contains an enzyme decomposition extract and an extract.

In addition, the content of the enzyme-degraded crude extract is 40 to 60% by weight, and the content of the wakoshi extract is 40 to 60% by weight.

Also, the oak wood vinegar aged for 6 years or more is further added.

Also, the amount of the oak wood vinegar solution is 1/500 times the amount of the mixed extract.

According to the composition for improving atopic skin according to the present invention, the oak wood vinegar aged for 6 years or more is further added to the mixed extract containing the enzyme decomposed extract of Aronia and the extract of Wakoshi as an active ingredient, It is more effective in treatment.

FIG. 1 is a view for explaining before / after treatment for acne treatment using the composition for improving atopic skin according to the present invention. FIG.
FIG. 2 is an illustration for explaining before / after treatment for childhood atopic treatment using the composition for improving atopic skin according to the present invention. FIG.
FIG. 3 is a diagram illustrating an example of before / after treatment for adult atopic treatment using the composition for improving atopic skin according to the present invention. FIG.
FIG. 4 is an exemplary diagram for explaining a treatment process for adult atopic treatment of FIG. 3; FIG.
5 is a graph for explaining the old skin horny change for adult atopic treatment of Fig.
FIG. 6 is a graph for explaining the erythema area change of the adult atopic treatment of FIG. 3; FIG.

Hereinafter, the present invention will be described more specifically.

The present invention relates to a composition for improving atopic skin in which an oak wood vinegar solution aged for 6 years or more is further added to a mixed extract containing an enzyme decomposed extract of Aronia and an extract of Wakoshi as an active ingredient.

According to one embodiment of the present invention, there is provided a functional cosmetic composition for improving atopic skin comprising a composition for improving atopic skin as an active ingredient.

According to an embodiment of the present invention, there is provided a pharmaceutical composition for improving atopic skin comprising as an active ingredient a composition for improving atopic skin.

&Lt; Composition for improving atopic skin >

The enzyme decomposition extract and the extract of Wakoshi contained in the composition for improving atopic skin according to the present invention are preferably extracted from leaf, stem, root, shell or a mixture of two or more thereof. Here, the mixed extract contains about 40 to 60% by weight of the enzymatically decomposed Aromania extract and about 40 to 60% by weight of the Wakosomal extract based on in-vitro experiments.

Particularly, the composition for improving atopic skin can increase the efficacy for improving atopy by further adding an oak wood vinegar aged for 6 years or more to the mixed extract of the enzyme decomposition extract and the extract of Wansong extract.

Aronia (Aronia) is a shrub native to North America, belonging to the Rosaceae, with small, sour fruits, which ripen in the late summer and fall immediately. The leaves are soft, gleaming and light green. Aronia berry is classified into two kinds according to its color. Red berries (Aronia arbutifolia) and red berries are called black berries (Aronia melanocarpa).

These Aronia fruits contain a large amount of sugars (20%), anthocyanins, polyphenols, vitamins B1 and B2, pantothenic acid, and flavonoids. Among these, anthocyanins are effective in blood circulation in the human body, helping the permeability of microvessels, elasticity of blood vessels, normalization of blood pressure, and providing a positive effect on the microvessels of the eyes, thereby improving visual acuity.

It is preferable to extract the leaves, stems, roots, or a mixture of two or more of them from the waxy seeds. This is because polysaccharide oligosaccharides, which have antifungal and antimicrobial activity, are distributed uniformly in all regions.

Wassong can have effects of moisturizing and soothing, whitening, and atopic improvement of skin due to various pharmacological actions, especially antibacterial and antipressive effects.

The wood vinegar is separated into three layers when the condensate obtained by cooling the smoke and steam generated in the process of carbonizing the oak (pyrolysis) is kept for a certain period. Usually, the upper layer (light oil) and the lower layer (tar) are separated Removed aqueous solution of the intermediate layer. That is, the oak wood vinegar is a light brown acidic liquid natural substance, most of which is water, and the other is a complex extract containing 2000 kinds of organic compounds such as organic acids, phenols, carbonyl compounds and alcohols and a large number of mineral components It has antibacterial, antiseptic, preservative and antioxidant effect.

The composition for improving atopic skin according to an embodiment of the present invention can suppress an allergic reaction that may occur in atopic skin or inhibit inflammatory skin.

A composition for improving atopic skin comprises a step of extracting an enzyme decomposed extract, a step of extracting an extract of Wassong, a step of producing a mixed extract by mixing the extracted enzyme-decomposed Aromania extract and a Wassong extract, And further adding an aged oak wood vinegar solution.

Enzymatic decomposition The step of extracting the Ahnoniae extract is to extract the anthocyanin contained in the shell component of Aronia through enzymatic decomposition and extract the extract of Wassong extract. The step of producing the mixed extract is carried out so that the enzymatically decomposed Aronia extract and the salted extract are respectively contained in an amount of 40 to 60% by weight. Particularly, in the step of adding the oak wood vinegar solution, the amount of the oak wood vinegar solution corresponding to 1/300 to 1/700 times the amount of the mixed extract is added, preferably the amount corresponding to 1/500 times.

Example 1: Cosmetic composition

The cosmetic product according to the present invention can be prepared in any conventional form and can be in the form of, for example, a solution, suspension, paste, gel, cream, lotion, powder, soap, surfactant- containing cleansing, oil, Liquid foundation, wax foundation, and spray, but the present invention is not limited thereto. It can be used as a raw material of various cosmetics such as external ointment, lotion, cream, softener, nutritional lotion, pack, essence, etc.

When the formulation of the present invention is a paste, a cream or a gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as a carrier component .

In the case where the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, a mixture of chlorofluorohydrocarbons, propane / Propane, such as butane or dimethyl ether.

When the formulation of the present invention is a solution or a milky liquid, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, 1,3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid esters of sorbitan.

When the formulation of the present invention is a supernatant liquid, it is preferable to use, as the carrier component, water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Microcrystalline cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is an interfacial active agent-containing cleansing, it is preferable to use, as the carrier component, aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolium derivative, methyltaurate, sarcosinate, Amide ether sulfate, alkylamidobetaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

When used in such a cosmetic composition, it is preferably 1 to 5% by weight on a dry weight basis. If it is contained in an amount of less than 1% by weight, no remarkable effect can be expected. If the concentration exceeds 5% by weight, the increase in the concentration is insignificant, and side effects may occur.

Example 2: Pharmaceutical composition

The pharmaceutical preparation according to the present invention may be prepared by any conventional formulation and may be formulated into tablets, emulsions, injections, external preparations and the like.

When used in such pharmaceuticals, the pharmaceutical composition according to the present invention is preferably contained in an amount of 15 to 30% by weight. When the concentration exceeds 30% by weight, the increase in the effect is insignificant with increase in the concentration, and side effects may occur.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention unclear.

The present invention relates to a method of treating atopic dermatitis, and more particularly, to a method of treating atopic dermatitis, which comprises administering a composition for improving atopic dermatitis according to the present invention, FIG. 3 is an exemplary view for explaining before / after treatment for adult atopic treatment using the composition for improving atopic skin according to the present invention. FIG.

1 to 3, compositions for improving atopic skin can be used for acne treatment and atopy treatment of children / adults.

Fig. 1 is a photograph showing before / after acne treatment of middle school boys. In the pre-treatment photographs, a lot of acne was formed on the skin. However, the photographs after the treatment with the compositions for improving atopic skin showed that the acne formed on the pre-treatment photographs was mostly weakened and the skin was soaked, and that the composition for improving atopic skin was effective for the acne.

FIG. 2 is a photograph showing before / after the treatment of atopy of a sixth grade girl in an elementary school. In the pre-treatment photographs, many keratin and erythema were formed on the old skin. However, the photographs after treatment with the compositions for improving atopic skin showed that the keratin formed on the pre-treatment photographs was removed, and the erythema was weakened and only partially appeared.

FIG. 3 is a photograph showing before / after treatment of intractable dry-type atopic disease in a 36-year-old middle-aged man who developed atopy from 15 years old. In the pre-treatment photographs, many keratin and erythema were formed on the old skin. However, the photographs after treatment with the compositions for improving atopic skin showed that the keratin formed on the pre-treatment photographs was removed, and the erythema was weakened and only partially appeared.

2 and 3, it was confirmed that the composition for improving atopic skin is effective for children and adult atopy.

FIG. 4 is a graph for explaining a treatment process for adult atopic treatment of FIG. 3, FIG. 5 is a graph for explaining an old skin keratinous change for adult atopic treatment of FIG. 3, This is a graph for explaining the erythema area change for atopic treatment.

4 to 6, the effect of the composition for improving atopic skin can be intuitively confirmed.

FIG. 4 shows a state in which the atopy is improved by treating the composition for improving atopic skin for 3 months to a 36-year-old middle-aged male who developed dry-type atopic disease from 15 years old. In other words, all of the left and right legs were identified before treatment (0 month of treatment), and thus, the appearance of old skin horny on the naked eye could hardly be confirmed at 3 months of treatment.

Specifically, the subject of the treatment showed a severe scarring phenomenon such as a snake taking off the skin due to irregular formation of the skin due to the irritation of the skin caused by itching and scraping. That is, in the case of the right leg, it was reduced to 40% and 20% at 1 month and 2 months, respectively, and almost no keratin was found at 3 months. In the left leg, more keratin could be identified than the right leg at 1 month of treatment, but it was judged to be due to the old difference of the old keratin before treatment. In the left leg, It was predicted that natural dropping was delayed by the dermis of the formation of the crust (Fig. 5).

The erythema was a typical symptom that can be confirmed at the site of atopy. At this time, no significant change was observed during 1 month and 2 months compared with before treatment, but erythema was almost not observed at 3 months of treatment. That is, the right leg was reduced to 85% and 90% at 1 month and 2 months, respectively, and erythema could not be confirmed at 3 months. Similarly, the left leg was reduced to 85% and 80% at 1 month and 2 months, respectively, and almost no erythema was observed at 3 months (FIG. 6).

Accordingly, the composition for improving atopic skin according to the present invention is an agent for treating atopy, and has an excellent effect for treating atopy than a conventional atopic skin improving product.

Claims

A composition for improving atopic skin, comprising an enzyme-decomposed Aromania extract and a Salmonella extract.

The method according to claim 1,
Wherein the content of the enzymatically decomposed extract is 40 to 60% by weight, and the content of the extract is 40 to 60% by weight.

The method according to claim 1,
Wherein the oak wood vinegar is aged for 6 years or more.

The method of claim 3,
The amount of the oak wood vinegar solution,
Wherein the amount of the mixed extract is 1/500 times the amount of the mixed extract.