KR20170024321A - The process of making healthcare compositions comprising fermented Dendropanax morbifera extracts and herbal medicines Abalone extracts - Google Patents

The process of making healthcare compositions comprising fermented Dendropanax morbifera extracts and herbal medicines Abalone extracts Download PDF

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KR20170024321A
KR20170024321A KR1020150119440A KR20150119440A KR20170024321A KR 20170024321 A KR20170024321 A KR 20170024321A KR 1020150119440 A KR1020150119440 A KR 1020150119440A KR 20150119440 A KR20150119440 A KR 20150119440A KR 20170024321 A KR20170024321 A KR 20170024321A
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abalone
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이준상
이영호
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L17/00Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • A23L17/40Shell-fish
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065Microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/20Natural extracts
    • A23V2250/204Animal extracts
    • A23V2250/2042Marine animal, fish extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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Abstract

The present invention relates to a method for fermenting a leaf-and-egg plant having various physiological activities such as antioxidant, anti-cancer, antibacterial, anti-inflammatory, anti-diabetic and anti-atopic effect, Extracts have excellent taste and nutrition, and are safe for abalone, an abundant seafood that is beneficial to the human body. It has been widely used as a medicinal herb since ancient times. Each herbal herb medicine has various pharmacological activities. The combination of hot water extracts of Abalone mixed abalone extracts with proper concentration so that they complement each other can be complemented without loss of physical properties and effective ingredients, Antioxidant, Anticancer, Antibacterial , Anti-inflammatory, anti-diabetic effect, functionally active ingredients known to have abilities such as abalone taste, nutrition and fatigue recovery, nourishing lotion, bio control, combined with functional pharmacological activities of herbal medicine herbal medicine, prevention of disease, restoration of disease, The function is added and the absorption rate is improved. The unpleasant taste and smell are removed, which not only gives a rich flavor but also improves the fragrance, thereby improving the sugar content, appearance, flavor and nutrition. To a method for producing a health functional combined extract comprising a mixture of a fermented extract of Yellow Grass seed and an abalone complex herbal water extract which is capable of inhibiting or preventing various adult diseases by allowing the plant to grow in one step as a functional food which satisfies needs at once.

Description

Technical Field [0001] The present invention relates to a method for preparing a health-functional complex extract comprising a mixture of a fermented extract of Hwangchu-mungbean tree and an abalone complex herbal water extract, wherein the fermented dendropanax morbifera extracts and the herbal medicines Abalone extracts

The present invention relates to a method for preparing a health-functional complex extract comprising a mixture of a fermented extract of Hwangyu-tree and an abalone complex herbal water extract,

More specifically, it has been shown that various nutrients such as antioxidant, anti-cancer, anti-bacterial, anti-inflammatory, anti-diabetic and anti-atopic effect have been identified by our own plant resources. Extracts have excellent taste and nutrition, and are safe for abalone, an abundant seafood that is beneficial to the human body. It has been widely used as a medicinal herb since ancient times. Each herbal herb medicine has various pharmacological activities. The combination of hot water extracts of Abalone mixed abalone extracts with proper concentration so that they complement each other can be complemented without loss of physical properties and effective ingredients, Antioxidant, anti-cancer, Antimicrobial, antiinflammatory, anti-diabetic effect, functionally active ingredients known to have the effects of abalone taste, nutrition and fatigue recovery, nourishment and so on, biomedical control combined with functional pharmacological activities of herbal medicines, prevention of diseases, The addition of the supplementary function, the absorption rate is improved, the unpleasant taste and smell are removed from the ingestion, and not only the richness but also the fragrance is perfected. By improving the sugar content, appearance, flavor and nutrition, The present invention relates to a method for producing a health functional combined extract comprising a mixture of a fermented extract of Yellow Grass seed and an abalone complex herbal water extract which is capable of inhibiting or preventing various adult diseases by allowing the plant to grow one step at a time.

In spite of the development of medicine and the increase of life expectancy, the possibility of cancer, heart disease, cerebrovascular disease and the like is increasing, and modern people are exposed to more diseases and health risks.

Therefore, the recent interest in healthy life and well-being is increasing by increasing the desire for healthy and high-quality life as well as prevention of diseases due to the improvement of economy and living standard, the development of medicine and the increase of life expectancy.

Also, since ancient times, in Korea, food and medicine have come out from the same place as food and medicine, and food and medicine are not separate and very closely related. In recent years, It has become more sophisticated and the desire and interest in health is heightened.

Hyundai health-oriented consumers who emphasize functional and hygienic aspects of food prefer health-functional foods that can prevent or eliminate diseases such as geriatric diseases and develop health-functional foods to satisfy them.

Natural plant material or medicinal herb contains various physiologically active substances and antioxidant substances, and exhibits various effects such as anti-aging, anti-cancer, anti-inflammation and immune function improvement. However, since it is unstable after being extracted and sometimes stimulant, In recent years, attempts have been made to stabilize natural extracts, reduce toxicity, or convert them to stable derivatives to enhance their effectiveness.

Dendropanax morbifera is an evergreen tree belonging to Araliaceae. It is found in some islands in the southern coast of Korea. When it bruises the bark of Yellow-eyed Tree, it releases a small amount of yellow liquid. This is called yellowish.

Since Hwangchil is not a place to throw away the whole tree, it has high economic value, greening of restoration of the natural environment, and economic income. It is definitely one of the best plants in the world. ,

The ingredients of Huangchil are composed of 66.7% of nonvolatile components, 10.8% of directional components, 8.1% of water and 14.4% of solids, which is a paint component that forms a golden coat. The directional component is composed mainly of cubebene, γ-selinene and δ-cadinene of sesquiterpene, and these components show sedative and tonic action on the nervous system, Is known to be effective for prevention, treatment and improvement of diseases in which the severity is increasing in modern society such as antioxidative effect, antihypertensive effect, anticancer effect, hepatocyte protective effect, and the like. It can be utilized as a medicine, and unlike lacquer, it is easy to handle without causing skin allergy, so it can be widely used as a health food by secondary processing of Huangchil moderately.

 Therefore, the above-mentioned yellowtail extracts a variety of various effective ingredients through analysis of the resin composition composition of the woody wood. In recent years, various health promotion and therapeutic effects have been known, and the use thereof has been gradually expanded to various functional beverages and pharmaceuticals New applications are exploiting.

However, although the clove components such as sesquiterpene contained in Huangchil have various pharmacological actions as well as a value as a health food that makes the mind and body clean and comfortable, some substances of sesquiterpene, In addition to showing unique directional characteristics, it also shows a bitter taste. Due to the characteristics of this directionality and bitter taste, when the aged solution is prepared only with the crude solution, it may give a negative feeling to the consumers. However, it is difficult to ingest the raw material and it is difficult to process the raw material. Since the pharmacological activity per unit weight is not strong, it is necessary to develop functional food having enhanced pharmacological effect than the original pharmacological effect of the herbal medicine .

Abalone also belongs to the pupae of the pupae of the pupae of the useful molluscs. It grows by the feeding of the seaweeds and is rich in minerals such as calcium and phosphorus, vitamins B1, B2 and protein. Especially, it is rich in taurine, Myocardial infarction and so on. It protects the skin and kidneys from the past, cleans the mouth (lips), opens the stomach, regulates seawater (cough), restores fatigue, Therefore, it is said that it is excellent for the optic nerve fatigue symptom of eyes which is used as a health food, and the shell of abalone is used in conjunctivitis and cataract, And processed food-related technologies are being developed, so consumption is gradually expanding.

However, in order to consume abalone as a low-fat high-protein food, it is necessary to take natural or cultured abalone to remove it and eat it by circuit ingestion, or by cooking with bamboo and hot water. By this method, There are disadvantages.

In addition, it is necessary to increase income of abalone farmers by promoting consumption by development of high value-added abalone food utilizing febrile species as an abalone which has low value of commodity of less than 3cm in length, There is a need.

The natural herbal medicine used in oriental medicine is low toxic or non toxic, does not remain in the body and does not cause drug tolerance. Herbal medicine herbal medicine has been used to treat various diseases. Especially when using herb medicine, Which has a strong point in the prophylactic part,

Hyundai is increasing the consumer's desire for health by complementing the ki and blood. From this point of view, it is common knowledge that common people know easily that it is a medicine which is made by herbal medicine Despite its efficacy, it is effective to take long-term doses, but it is difficult for consumers to consume on a regular basis as they eat food on a daily basis.

Therefore, in spite of the scientifically proven high efficacy, Chinese medicine has been reluctant to take herbal medicine because of the inconvenience caused by storage, drinking, and herbal odor.

In the prior art, the prior arts are also mixed so that the extracts of Huchilchu, Abalone and herbal medicines, which have proved their functional effects, can be synergistically complementary without deteriorating their physical properties, , Nutritional function, sensory palatability, and health promotion function effects such as increasing resistance to various diseases of active active ingredients for each function at the same time, Have common problems

Document 1: Korean Patent Registration No. 10-0988072

(Fennel wood fermented product and pharmaceutical composition containing it, Announcement date October 18, 2010)

Document 2: Korean Patent Registration No. 10-1333007

(Extraction method of yellowtail millet extract, date of announcement November 26, 2013)

Document 3: Korean Patent Registration No. 10-0902539

(Functional Beverage Composition Containing Abalone Extract and Method for Producing the same, Date of Announcement: June 15, 2009)

Accordingly, the present invention provides a fermented product of a woody plant having increased pharmacological activity of Hwangchu-japon, which is a fermented product of Hwangchu-wood extract having various physiological activities, an abalone extract having excellent taste and nutrition, It is possible to naturally take it in mutual coexistence without having to separately take ingredients such as Huangchil, abalone, and Chinese herbal medicine which are beneficial to the body, by providing the mixed extract which is mixed to be synergistically effective. Health functionalities, and functional foods that meet the various needs of consumers at the same time, thereby making it possible to prevent or prevent various adult diseases. To develop It will cost.

As described above, prior art extracts of Huangchu tree, abalone extract, and medicinal herb extract, which have respective functional characteristics at the time of use, have various problems,

In addition to excellent anticancer activity, which is easily absorbed in vivo according to the characteristics, it has an antioxidant activity, which enhances the pharmacological activity of Huangchil. So that the herbal complex herbal medicine combined with the herbal medicine herbal medicine has the effect of enhancing the pharmacological effects inherent in the herbal medicine, so that the herbal mixed hot-water extract of abalone can be synergistically complemented without loss of the respective properties and effective ingredients By mixing and compounding at an appropriate concentration,

It is possible to effectively and continuously take advantageous ingredients of Huangchil, abalone, and Chinese herbal medicines under mutual coexistence without needing to separately take Huangchil, Abalone and Chinese medicinal materials useful for the body, And an abalone complex herbal mixed water extract of the present invention to solve the technical problem that needs to be developed.

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned problems of the prior art,

It is a fermented extract of Hwangchu tree which enhances the pharmacological activity of Hwangchu tree by fermenting the leaves and branches of Hwangchu tree which have various physiological activities such as antioxidant, anti-cancer, antibacterial, anti-inflammation, anti-diabetic and anti- It has been proven that it is safe for abalone, which is excellent in nutrition and abundant seafood for human body. It has been widely used as a medicinal herb since ancient times. Each compound herb medicine has various pharmacological activities. The extracts were mixed with each other at a proper concentration so that they could complement each other without loss of physical properties or active ingredients, and thus they were highly stable and safe. Antioxidant, anti-cancer, anti-bacterial, anti-inflammatory, anti Diabetic effect, functionally active ingredients known to have abilities such as abalone taste, nutrition and fatigue recovery, and nourishing tonic, biological control of diseases in which functional pharmacological activities of complex herbal medicine are combined, disease prevention, disease restoration, It improves absorption rate and unpleasant taste and smell unpleasant to intake. It not only gives a rich flavor but also improves fragrance and improves sugar content, appearance, flavor and nutrition, so that combined with functional effect, taste and nutrition are combined to meet various needs of consumers at once The present invention also provides a method for preparing a health functional combined extract comprising a mixture of a fermented extract of Huangchu tree and an abalone complex herbal extract capable of inhibiting or preventing various adult diseases.

As described above, according to the present invention, the health functional combined extract comprising a mixture of the fermented extract of Huangchu tree and the herbal mixed hot water extract of Abalone,

It has excellent stability and safety due to the enhancement effect than the original pharmacological effect. It has the antioxidant, anti-cancer, antibacterial, anti-inflammatory, , Which is known to be effective for the prevention of diseases, disease control, restoration of health, improvement of absorption rate, improvement of absorption rate, unpleasant taste and smell are removed, By enhancing the sugar content, appearance, flavor and nutrition by improving the flavor not only on this day but also by improving the taste and nutrition by combining the functional effects and the various needs of the consumers at once, Inhibition or prevention.

Especially, extraction of active ingredient of Huangchil is possible because it can maintain the quality of Huangchil because it does not go through the heating process and minimizes the loss of Huangchu component, so it is possible to maintain high quality and can be stored for a long period of time. .

In addition, the present invention can be easily taken by anyone, and the physiologically active substance and the nutrients are mixed evenly, and the abalone and the herbals effective ingredients are harmonized with the ingredients of the Huangchil extract to reduce the bitter taste and aroma unique to herbal medicine and herbal medicine, And flavor, along with the unique odor of fish and shellfish is removed, and it is lightened. By comprehensively satisfying the requirements for use as a multifunctional health functional food required by health-oriented modern consumers such as functionality, nutrition, taste and hygiene, The disease can be prevented or solved, and the health of the busy modern people who can not take the health separately can be greatly helped in health care.

The present invention can be freely applied to raw materials for foods, raw materials for drinking water and drinking water, raw materials for pharmaceuticals, raw materials for functional foods, raw materials for cosmetics, and the like.

In addition, the present invention has the effect of increasing the commerciality by upgrading the abalone and adding value, and it is possible to utilize the abalone of the undeveloped culture having a low value of the product of less than 10 cm in length, which accounts for a large portion of abalone aquaculture production, The development of high value-added abalone foods that can increase the value added will promote consumption, which will help improve the farm income of abalone farmers.

In order to achieve the above object, the present invention will be described in detail.

The present invention relates to a method for preparing a health functional combined extract comprising a mixture of a fermented extract of Fusarium oxyslavatus and an abalone complex herbal extract, in which various physiological activities such as antioxidation, anti-cancer, antibacterial, anti-inflammatory, anti-

The washed and dried yellowtail leaf, the yellowing tree branch and the germinated brown rice were separately pulverized to a diameter of about 1 mm using a pin mill and then pulverized in a turbo mill at a beater rotational speed of 6,750 rpm Air classifying wheel speed of 5,000-7,500 rpm in the air classifier to classify the powdery material of the ultra-fine powdered yellowtail leaf, yellowtail millet and germinated brown rice as the cell wall in a weight ratio of 2 : 1: 0.1 ratio, and 5% by weight of the fermented microorganism and the yamaya enzyme were added to the mixture, respectively, and fermented for 48 hours in an enzyme fermenter for 48 hours to increase the pharmacological activity of the yellowtail. A wood fermentation extract was prepared,

The raw abalone was washed with purified water and extracted from the extractor at a temperature of 115 ° C to 130 ° C for 4 hours. The raw abalone was separated from the meat and the viscera and ground. The liquid and solid abalone extracts thus obtained were ground, Natural herb medicines containing one or more active ingredients at a composition ratio (weight ratio) of at least one active ingredient are mixed at a ratio of 10: 2 (weight ratio), and the mixture is introduced into an extractor And the mixture was mixed at a mixing ratio (weight ratio) of 3: 7 to the combined extracts of Hwangchu and Abalone. Then,

The fermented extract of Huangchu tree, which is prepared by mixing 3% by weight of the fine powder of the finely pulverized leaves of Huangchu tree, which is prepared by mixing tea extracts of the mixed extract of Huangchu tree and abalone, And an abalone complex herbal water extract to produce a health functional combination extract.

In the present invention, the fermented extract of Huangchu tree is fermented by a low-temperature extraction method which optimizes the active ingredients and fermented the leaves and branches of Huangchu tree to enhance the pharmacological activity of the Huangchu tree. The cell membrane is destroyed and the microorganisms are finely crushed and the active ingredient contained therein is dissolved in water and the dissolved fermentation product is formed so as to be easily absorbed in the body. Since the temperature is lower than that of the heat extraction method, the oil component is destroyed by heat It is possible to prevent deterioration.

In addition, in the present invention, the leaves and branches of Uchilchogakus were used in the present invention. In the present invention,

ACM (air classifier mill) crushing method which is a double milling and classification function of pin mill and turbo mill is applied to the ultra fine pulverization process of crushing the leaves, branches and germinated brown rice with ultrafine powder and destroying strong cell walls The absorption rate of active ingredient of the leaves and stems of Hwangchu - gil was improved to solve the problem of gastrointestinal disorder caused by ingestion.

The addition of micro-pulverized germinated brown rice at the low temperature fermentation extraction of Hwangjak tree can supply the carbohydrate used for fermentation and can be formed into ultrafine fine powder which not only enhances sweetness but also has good hardness for neck turn.

Germinated brown rice is a processed food that germinates general brown rice at about 0.5 to 2 mm to improve the texture and texture of rough brown rice and increase the nutrients (functional ingredients)

In germinated brown rice, the content of GABA is 10 times higher than that of white rice, 3 to 5 times higher than brown rice, and 3 times higher than that of octacosanol and dietary fiber. In addition, germinated rice also contains minerals such as calcium, iron, zinc and vitamins .

In the present invention, the microorganisms to be added in the production of the fermented extract of Wuchulia chinense are Aspergillus oryzae, Aspergillus kawauchi, Aspergillus niger, Bacillus subtilis, or hiochibacteria One or more food fermenting microorganisms selected from the group consisting of

These microorganisms are exemplified for illustrative purposes only, and various microorganisms known to be beneficial can be used for producing the above-described fermented extract of Hokkaido tree. The microorganisms may be obtained by using bacteria existing in a natural state, It may be used, or it may be used after received from a microorganism depository.

Particularly, in the present invention, in the case of extracting the complex extract by mixing the fermented extract of Huangchu tree with the herbal mixed hot water extract of abalone at a mixing ratio (weight ratio) of 7: 3, the effective microorganism In order to induce the protein on the hot-water extract to be more effective for the ingestion into the human body,

This is because the leaves and branching powders of Hwacheon-gil, which have an ultrafine powder and increased absorption rate of the active ingredient, can further improve the efficacy of the composite composition of the present invention in addition to fermentation,

Compared with the mixed hot-water extract of Oriental herb complex mixed with herbal mixture, the ratio of economic composition including the extract of Huangchil was higher than that of high-priced abalone while utilizing the original taste and flavor of Huangchil .

The fermented extract of Huangchu tree of the present invention may be extracted with only the fermenting microorganism of the food, but it is preferable to add the soybean enzyme. When the soybean enzyme is fermented by adding the microorganism to the microorganism under the above-mentioned conditions, it becomes possible to produce the fermented extract having a deeper flavor by allowing the enzyme to proceed more quickly with microbial fermentation. Since the reaction may not be performed well even if fermentation is carried out by inoculating the microorganism as a raw material in which a large amount of components are present, the ANO enzyme is added to the microorganism in order to solve such a problem.

It is widely used in oriental medicine and herbal medicines. Due to its diversity and functionality, attention has been focused on the development of preventive and therapeutic materials for dementia, and various studies have been conducted. The inhibition of brain accumulation of acetylcholine esterase inhibitor, Improvement of oxidative stress, effect of estrogenic effect and the like. In the present invention, a large amount of useful microorganisms are contained, and not only pharmacologically excellent effects are exhibited, but also preference is improved, so that anyone can easily ingest them Be made

According to the present invention, the fermented extract of Huangchu tree is fermented at low temperature by adding food fermenting microorganism and artificial yeast enzyme so that the bitterness and odor of Huangchil are removed and the active ingredient can be maintained,

The fermented extract of Fusarium oxysporum, which has enhanced the pharmacological activity of the Fusarium oxyspergens by fermenting the fermentation microorganism and the actinomycetes in the enzyme fermentation tank at a low temperature by the action of the heat extraction method of the prior art, In order to increase various effects such as antioxidant efficacy and antioxidant, anti-cancer, antibacterial, anti-inflammatory, anti-diabetic and anti-atopic effect,

It is intended to further improve the pharmacological effect of the extract of the extracts due to the maintenance of the nature of the leaves and branches of the perennial Aspergillus species by minimizing the loss of the components without heat treatment, By eliminating the characteristic bitter taste and odor, it prevents the ingestion of food and improves the preservability, so it can be stored for a long time.

In addition, the fermented extract of Huangchu tree of the present invention has the highest antioxidant power and anticancer ability among leaves, roots, stems, and fruits, and also has 2: 1 (Weight ratio), and the resulting mixture is subjected to fermentation extraction.

In addition to the unpleasant taste and smell removed by ingestion by the combination of the leaves and branches of Hwangchilmyeon, the powder of Hwangchilgwaeus which is finally added after mixing with the Abalone herbal extract, The composition of the present invention is not only reduced in flavor and flavor but also improves the sugar content, appearance, flavor and nutrition of the composition of the present invention, Is satisfied.

In the leaves, branches and roots of Hwangchujak tree, more than 10 components including isohumulene, 2-hexenal, n-octanal and ethyl-3-hexenoate are eluted. Of these components, isohumulene 2-hexenal has a pungent or apple flavor, ethyl-3-hexenoate has a pineapple flavor, and n-octanal has a mellow taste of mushrooms. , It is possible to alleviate the strong flavor and bitter taste of Huangchil when the leaves and branches are fermented together and extracted.

In the above-mentioned fermented extract of Fusarium oxysporum of the present invention, it is preferred that the Fusarium oxysplasia is a mixture of at least one of leaves and branches rich in active active ingredients,

In order to extract the active ingredient of Hwangchujang, it is preferable that the blend ratio of the Hwangchujangguli leaves and branches is used in a weight ratio of 2: 1.

In the above fermentation, the perennials can be used as leaves and branches of raw perennials. However, the leaves and branches of perennials are dried to prevent the taste, flavor and color of the perennial perennials And to minimize nutrient destruction.

Since Huangchuang is a plant herbal medicine which has been proven to be safe for a long period of time, the Huanghui tree fermented product according to the present invention, which is made using the same as a raw material, has an advantage that a more effective pharmacological effect can be obtained without various side effects due to the use of a drug

In particular, it has been found that the extract of Huangchu tree that is native to the West and South coast of Jeonnam province is excellent in promoting activity against immune cells and nerve cells and has high antimicrobial activity against causative agents of food poisoning. In the present invention, As a general rule.

In the present invention, the above-mentioned conditions for producing the fermentation extract of Huangchu tree may be an optimization condition for fermentation. If these ratios are changed, the extraction efficiency of active ingredients of Huchulchu tree through fermentation extraction process may be lowered or the flavor may be significantly lowered.

In addition, the Abalone herbal mixed-fiber hydrothermal extract has been proven safe for abalone, which is excellent in taste and nutrition and is beneficial to the human body, has been widely used as a medicinal herb for a long time. Each herbal medicine herbal medicine having various pharmacological activities, In order to have an enhanced effect than the effect,

The raw abalone was washed with purified water and extracted from the extractor at a temperature of 115 ° C to 130 ° C for 4 hours. The raw abalone was separated from the meat and the viscera and ground. The liquid and solid abalone extracts thus obtained were ground, Natural herb medicines containing one or more active ingredients at a composition ratio (weight ratio) of at least one active ingredient are mixed at a ratio of 10: 2 (weight ratio), and the mixture is introduced into an extractor And the mixture is mixed at a mixing ratio (weight ratio) of 3: 7 to the combined extract of Hwangchu and Abalone.

In the above process, the raw abalone is extracted at a high pressure and the mixture containing the medicinal herb is extracted at a low temperature so as not to injure the active ingredient of the medicinal herb.

In the case of extracting the herbal mixed-fiber hydrothermal extract of the present invention, if the hydrothermal extraction conditions are less than the above-defined range, each effective ingredient contained in the herbal medicinal herb mixture may not be extracted sufficiently, If the hot water extraction conditions exceed the above-defined range, the respective active ingredients contained in the herbal medicine mixture may be destroyed and lose their efficacy. Therefore, after the heating step, It is preferable to increase the content and flavor of the extract by removing a large amount of water,

Concentration can be selectively achieved by concentration under reduced pressure, concentration in vacuum, extraction using a multiple extractor, and evaporation and evaporation.

The abalone, called the wild ginseng of the sea, has a high content of amino acids, especially glutamic acid, arginine, histidine, tyrosine, and taurine. It is rich in minerals such as vitamin, calcium, phosphorus, iron and iodine. Healthy food is good.

The above-mentioned abalone can utilize meat and visceral pulverized material. However, by utilizing the abalone shell containing a large amount of insoluble calcium at the same time, it is possible to improve the flavor by eliminating odor of herb medicine,

As bitterness and fragrance specific to Huangchil and Chinese medicine are reduced, abundant nutrition and taste of abalone are improved, and the smell unique to seafood is removed. It is possible to satisfactorily satisfy the combined use requirement characteristics of the health functionalities required by the consumers as health functional foods, and also to efficiently and efficiently produce the undeveloped growing type abalone, which has a low value of less than 10cm in length, The utilization of the febrile species and the added value thereof can be increased, and the income of the abalone farmers is also increased.

Therefore, the herbal hot-water extract of Abalone to be mixed with the present invention maintains the inherent taste, nutrition and function of the abalone to function as a basic function such as biological control, disease prevention and disease recovery, By effectively showing one part of the blood, it is possible to maintain health and treat diseases quickly.

In other words, food and medicine are derived from the same meaning. As the meaning of food and medicine is the same as food and medicine, they are not closely related to each other. Therefore, by adding herbal medicine to abalone, And it is increased in complexity.

In extracting the herbal composition complex hot-water extract of the present invention,

The herbal medicinal materials to be added such as abalone are added as one or more effective ingredients at a composition ratio (weight ratio) of one or more raw materials such as Jujube, Punggi, Sukjanghwang, Angelica, Peony, Licorice, Cinnamon, The mixing ratio of the herbal medicinal herb mixture is such that by mixing the herbal medicines in an equal amount, the synergistic effect of the synergistic effects due to the complementary action of the active ingredients contained in each medicament can be realized, It is preferable to use herbal medicines or medicinal herbal extracts in which the respective medicines are sliced into appropriate sizes and the medicinal herb extract powder which has been finely pulverized and removed from the impurities.

The herbal medicine used in the present invention is widely used as a medicament since the medicinal effect is described in detail in the medicinal herb medicine.

Cinnamon activates the function of the stomach and the rain, so it is widely used in digestive disorders due to digestive disorders, abdominal pain and diarrhea caused by stomach upsets. Angelica promotes circulation of blood which facilitates blood circulation, anti-cancer effect and blood pressure lowering effect, Suppression, improvement of constipation through promotion of bowel movement, and eosinophilia.

Glycyrrhiza is a medicinal substance that shows typical ginseng with ginseng. It stops the sweating and stops sweating. It is a medicinal substance which shows the typical period with ginseng. And licorice will function as a solubilizer that solubilizes the natural preservative and poorly soluble substance. It can inhibit the propagation of bacteria, and when added, sweetness can be reinforced and the progress of rancidity can be lowered.

In addition, a mixture of 100% by weight of a mixed composition comprising a mixture of a mixture of a mixture of a mixture of a mixture of a fermented extract of Hwangchil-myeon and an abalone complex, and 3% by weight of a fine powder of Hwangchu- Health functional composite extract,

It is very difficult to separate the fruit and seed as well as the amount of the fruit of the yellowtail tree. Therefore, instead of the fruit,

It is a raw material to be added to the combined extracts of the mixed extract of Hwangchu tree fermented with abalone and herbal mixed water extract. It is possible to maintain the inherent efficacy and to produce a richer aroma and taste,

The addition of finely ground powder of ugly Hwangchiljang leaves, which have freshness, sweetness and flavor, has a function as a medicinal material, but it is not easy to ingest, and by eliminating the rejection feeling due to the directionality and bitter taste of herbal medicine, It is possible to easily take it by elevating the amount of the drug,

As a result, the present invention is an invention that combines the effects of organic compounds of Huangchil, abalone, and herbal medicines by maintaining the intrinsic properties of the respective components as they are, and is a combination of food stability, nutritional functionality, sensual tastiness, Functional effect It is a functional food that satisfies consumers' various needs at the same time by simultaneous implementation. It is a unique food of Hwalchil combined with unique taste and fragrance of Chinese medicine, so it does not damage the active ingredient and purifies the taste and flavor with deep flavor. The palatability of the composition of the present invention can be naturally consumed, so that children and the elderly can eat the abalone fed with the feed additive of the present invention with confidence, thereby realizing a dietary life improvement effect and health promotion effect. Especially, If you have a dislike or long-term herbal intake Or no intake of herbal experience if one is effective when taken, if necessary, a preliminary herbal intake.

Example:

1. Manufacture of Fermented Extracts of Wooden Millet

The washed and dried yellowtail leaf, the yellowing tree branch and the germinated brown rice were separately pulverized to a diameter of about 1 mm using a pin mill and then pulverized in a turbo mill at a beater rotational speed of 6,750 rpm Air classification at an air classifying wheel speed of 7,500 rpm in an air classifier to give a powder mixture of powdery materials such as ultrafine granular leaf, : 0.1% fermented extracts of fermented Phellodendron japonica with fermentation of 5% by weight of fermented microorganism and wild type herbaceous enzyme, respectively, and fermentation for 48 hours at low temperature in an enzyme fermentation tank. .

2. Manufacture of herbal mixed water extract of abalone

The raw abalone was washed with purified water and extracted at a temperature of 130 캜 for 4 hours in an extractor. The raw abalone was separated into meat and viscera and ground. The liquid and solid abalone extracts obtained by pulverization were divided into jujube, (Weight ratio) containing at least one active ingredient and a composition ratio (weight ratio) of at least one active ingredient, peach, licorice, cinnamon, white bream, Was extracted for 2 hrs.

3. Preparation of Health Functional Composite Extracts Mixed with Fermented Extract of Hwangchu-wood and Combined Hot Water Extract of Abalone

The combined extracts of Hwangchu and Abalone were prepared by mixing the fermented Hwangchu-wood extracts extracted in the first step and the herbal complex hydrothermal extracts extracted in the second step at a mixing ratio (weight ratio) of 3: 7,

In the mixed extract of the mixture of the above-mentioned mixed greens and abalone, the fine powder of the finely pulverized greens obtained by mixing tea was mixed with 3% by weight of the combined extracts of the greens and the abalone, Mixed herbal extracts were prepared.

 The health functional combined extract of the present invention comprising the fermented extract of Fusarium oxysporum species and the herbal composition complex hot water extract of Abalone,

It is a fermented extract of Hwangchil tree which fermented Hwangchu tree leaves and branches and enhanced the pharmacological activity of Hwangchu tree. It has a unique taste and nutritional value. It has abundant seafood which is beneficial to the human body. The combination of the herbal mixed hot-water extracts of Abalone extracted with the mixture composition so as to have an enhanced effect than that of the pharmacological effect is mixed with the appropriate concentration so as to be capable of synergistically complementing each other without reducing the physical properties and eliminating the active ingredient, The antioxidant, anti-cancer, anti-bacterial, anti-inflammatory and anti-diabetic effects inherent to the extract of Hwangchu tree and the functional active ingredients known to have the effects of abalone taste, nutrition and fatigue recovery, The biological control of complex pharmacological activities of herbal medicine, It improves the prevention of disease, restoration of disease, and supplementation function. It improves absorption rate, eliminates unpleasant taste and odor, and makes it richer and more fragrant. It also improves sugar content, appearance, flavor and nutrition. have.

While the present invention has been described in connection with certain exemplary embodiments, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. .

Claims (3)

The present invention relates to a method for preparing a health functional combined extract comprising a mixture of a fermented extract of Huangchu tree and an abalone complex herbal water extract,
The washed and dried yellowtail leaf, the yellowing tree branch and the germinated brown rice were separately pulverized to a diameter of about 1 mm using a pin mill and then pulverized in a turbo mill at a beater rotational speed of 6,750 rpm Air classifying wheel speed of 5,000-7,500 rpm in the air classifier to classify the powdery material of the ultra-fine powdered yellowtail leaf, yellowtail millet and germinated brown rice as the cell wall in a weight ratio of 2 : 1: 0.1 ratio were mixed with 5% by weight of fermented microorganism and wild yeast enzyme, respectively, and fermented for 48 hours at low temperature in an enzyme fermentation tank to increase the pharmacological activity of yellowtail. A fermented extract was prepared,
The raw abalone was washed with purified water and extracted from the extractor at a temperature of 115 ° C to 130 ° C for 4 hours. The raw abalone was separated from the meat and the viscera and ground. The liquid and solid abalone extracts thus obtained were ground, Natural herb medicines containing one or more active ingredients at a composition ratio (weight ratio) of at least one active ingredient are mixed at a ratio of 10: 2 (weight ratio), and the mixture is introduced into an extractor And the mixture was mixed at a mixing ratio (weight ratio) of 3: 7 to the combined extracts of Hwangchu and Abalone. Then,
The mixture of the mixture of the mixture of the above-mentioned mixture with the mixture of the yellowtail millet and the abalone is prepared by mixing the fine powder of the millet of the yellowtail mill, Preparation of Health Functional Composite Extracts Composed of Mixed Hot Water Extract of Oriental Herbals
The fermenting microorganism according to claim 1, wherein the fermenting microorganism is one or more fermenting microorganisms selected from the group consisting of Aspergillus oryzae, Aspergillus kawauchi, Aspergillus niger, Bacillus subtilis or hiochibacteria A method for producing a health functional combination extract comprising a mixture of a fermented extract of Huangchu tree and an abalone herbal mixed hydrothermal extract The method according to claim 1,
In the process of preparing the herbal composition complex hot water extract of Abalone, the raw abalone is extracted at a high temperature, and the abalone mixture containing the herbal medicine is extracted at a low temperature to extract the active ingredient of the herb medicine without causing any harmful effect. Preparation of Health Functional Composite Extract Mixed with Mixed Hot Water Extract
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