KR20160111039A - 알츠하이머 질환을 치료하는 방법 - Google Patents
알츠하이머 질환을 치료하는 방법 Download PDFInfo
- Publication number
- KR20160111039A KR20160111039A KR1020167024829A KR20167024829A KR20160111039A KR 20160111039 A KR20160111039 A KR 20160111039A KR 1020167024829 A KR1020167024829 A KR 1020167024829A KR 20167024829 A KR20167024829 A KR 20167024829A KR 20160111039 A KR20160111039 A KR 20160111039A
- Authority
- KR
- South Korea
- Prior art keywords
- antibody
- seq
- hvr
- patient
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020217030556A KR20210121288A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461937472P | 2014-02-08 | 2014-02-08 | |
| US61/937,472 | 2014-02-08 | ||
| US201461971479P | 2014-03-27 | 2014-03-27 | |
| US61/971,479 | 2014-03-27 | ||
| US201462010259P | 2014-06-10 | 2014-06-10 | |
| US62/010,259 | 2014-06-10 | ||
| US201462081992P | 2014-11-19 | 2014-11-19 | |
| US62/081,992 | 2014-11-19 | ||
| PCT/US2015/014758 WO2015120233A1 (en) | 2014-02-08 | 2015-02-06 | Methods of treating alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217030556A Division KR20210121288A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160111039A true KR20160111039A (ko) | 2016-09-23 |
Family
ID=52684643
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167024829A Ceased KR20160111039A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
| KR1020247018360A Withdrawn KR20240094017A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
| KR1020237013210A Ceased KR20230056800A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
| KR1020217030556A Ceased KR20210121288A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247018360A Withdrawn KR20240094017A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
| KR1020237013210A Ceased KR20230056800A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
| KR1020217030556A Ceased KR20210121288A (ko) | 2014-02-08 | 2015-02-06 | 알츠하이머 질환을 치료하는 방법 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20150246963A1 (enExample) |
| EP (2) | EP3718563A1 (enExample) |
| JP (4) | JP6685912B2 (enExample) |
| KR (4) | KR20160111039A (enExample) |
| CN (1) | CN106163548A (enExample) |
| AU (1) | AU2015214058B2 (enExample) |
| BR (1) | BR112016018170A2 (enExample) |
| CA (1) | CA2938466C (enExample) |
| CL (2) | CL2016001979A1 (enExample) |
| HK (1) | HK1231401A1 (enExample) |
| IL (1) | IL246999B (enExample) |
| MX (1) | MX380252B (enExample) |
| MY (1) | MY179105A (enExample) |
| NZ (1) | NZ723884A (enExample) |
| RU (1) | RU2724190C2 (enExample) |
| SG (2) | SG10201913637RA (enExample) |
| TW (1) | TWI705824B (enExample) |
| WO (1) | WO2015120233A1 (enExample) |
| ZA (1) | ZA201605341B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019182319A1 (ko) * | 2018-03-20 | 2019-09-26 | (주)인벤티지랩 | 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물 |
| US11400085B2 (en) | 2018-03-20 | 2022-08-02 | Inventage Lab Inc. | Method for preparing pharmaceutical composition for preventing or treating cognitive impairment-related disease and pharmaceutical composition for preventing or treating cognitive impairment-related disease prepared by the same |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2941415A1 (en) * | 2014-03-21 | 2015-09-24 | Alzheon, Inc. | Methods for treating neurological disorders |
| MA41115A (fr) | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
| GB2541003A (en) * | 2015-08-05 | 2017-02-08 | Kran Life Sciences Llp | Neurodegenerative disorders |
| KR102547164B1 (ko) * | 2015-09-10 | 2023-06-22 | 알제온, 인크. | 특정 환자 집단에서 신경퇴행성 장애를 치료하는 방법 |
| US11135313B2 (en) * | 2015-10-28 | 2021-10-05 | The Trustees Of The University Of Pennsylvania | Intrathecal administration of adeno-associated-viral vectors for gene therapy |
| CN114019170A (zh) * | 2016-01-20 | 2022-02-08 | 基因泰克公司 | 用于阿尔茨海默氏病的高剂量治疗 |
| IL263433B2 (en) * | 2016-06-07 | 2024-03-01 | Biogen Int Neuroscience Gmbh | Methods for treating alzheimer's disease |
| CA3032289A1 (en) * | 2016-07-29 | 2018-02-01 | Biogen Chesapeake Llc | Methods of treating or preventing amyloid related imaging abnormalities associated with alzheimer's disease treatment |
| IT201600118499A1 (it) * | 2016-11-25 | 2018-05-25 | Giacomo Koch | Uso di agonisti dopaminergici per la prevenzione della progressione della malattia di Alzheimer allo stadio precoce. |
| US12290516B2 (en) | 2017-05-12 | 2025-05-06 | The Hong Kong University Of Science And Technology | Heterocyclic compounds as EphA4 inhibitors |
| SMT202300129T1 (it) | 2017-08-22 | 2023-05-12 | Biogen Ma Inc | Composizioni farmaceutiche contenenti anticorpi anti-beta amiloide |
| BR112020020351A2 (pt) | 2018-04-05 | 2021-01-12 | Calasia Pharmaceuticals, Inc. | Agentes farmacológicos para o tratamento de doenças oculares |
| JP2024526880A (ja) | 2021-07-22 | 2024-07-19 | ジェネンテック, インコーポレイテッド | 脳標的化組成物及びその使用方法 |
| WO2025245381A1 (en) | 2024-05-23 | 2025-11-27 | The Trustrees Of Dartmouth College | Methods and compositions for enhancing the persistence of car expressing tregs in the cns and other tissues |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019182319A1 (ko) * | 2018-03-20 | 2019-09-26 | (주)인벤티지랩 | 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물 |
| US11400085B2 (en) | 2018-03-20 | 2022-08-02 | Inventage Lab Inc. | Method for preparing pharmaceutical composition for preventing or treating cognitive impairment-related disease and pharmaceutical composition for preventing or treating cognitive impairment-related disease prepared by the same |
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