KR20160079823A - 티에노트리아졸로디아제핀 화합물을 함유하는 제약 제제를 사용하여 백혈병을 치료하는 방법 - Google Patents

티에노트리아졸로디아제핀 화합물을 함유하는 제약 제제를 사용하여 백혈병을 치료하는 방법 Download PDF

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KR20160079823A
KR20160079823A KR1020167013580A KR20167013580A KR20160079823A KR 20160079823 A KR20160079823 A KR 20160079823A KR 1020167013580 A KR1020167013580 A KR 1020167013580A KR 20167013580 A KR20167013580 A KR 20167013580A KR 20160079823 A KR20160079823 A KR 20160079823A
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compound
solid dispersion
formula
carbon atoms
pharmaceutically acceptable
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마리아 이 리베이로
에릭 레이몬드
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온코에틱스 게엠베하
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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KR1020167013580A 2013-11-27 2014-11-26 티에노트리아졸로디아제핀 화합물을 함유하는 제약 제제를 사용하여 백혈병을 치료하는 방법 Withdrawn KR20160079823A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361909702P 2013-11-27 2013-11-27
US61/909,702 2013-11-27
US201462012128P 2014-06-13 2014-06-13
US62/012,128 2014-06-13
US201462080804P 2014-11-17 2014-11-17
US62/080,804 2014-11-17
PCT/EP2014/075709 WO2015078929A1 (en) 2013-11-27 2014-11-26 Method of treating leukemia using pharmaceutical formulation containing thienotriazolodiazepine compounds

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KR20160079823A true KR20160079823A (ko) 2016-07-06

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KR1020167013580A Withdrawn KR20160079823A (ko) 2013-11-27 2014-11-26 티에노트리아졸로디아제핀 화합물을 함유하는 제약 제제를 사용하여 백혈병을 치료하는 방법

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US (1) US9757385B2 (enExample)
EP (1) EP3074018A1 (enExample)
JP (1) JP2016538310A (enExample)
KR (1) KR20160079823A (enExample)
CN (1) CN105960239A (enExample)
WO (1) WO2015078929A1 (enExample)

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CN106029077A (zh) * 2013-08-01 2016-10-12 翁科埃斯克斯有限公司 包含噻吩并三唑并二氮杂卓化合物的药物制剂
KR20160145833A (ko) * 2014-05-02 2016-12-20 온코에틱스 게엠베하 티에노트리아졸로디아제핀 화합물을 사용한 급성 골수성 백혈병 및/또는 급성 림프아구성 백혈병의 치료 방법
WO2015168555A1 (en) * 2014-05-02 2015-11-05 Oncoethix Sa Method of treating resistant non-hodgkin lymphoma, medulloblastoma, and/or alk+non-small cell lung cancer using thienotriazolodiazepine compounds
CN107427524A (zh) * 2014-08-28 2017-12-01 翁科埃斯克斯有限公司 利用包含噻吩并三唑并二氮杂*化合物的药物组合物治疗急性髓细胞白血病或急性淋巴性白血病的方法
US10702517B2 (en) 2015-04-22 2020-07-07 Celgene Quanticel Research, Inc. Bromodomain inhibitor
AU2016304856B8 (en) * 2015-08-10 2021-02-18 Dana-Farber Cancer Institute, Inc. Mechanism of resistance to BET bromodomain inhibitors
JP6864379B2 (ja) 2016-03-31 2021-04-28 オンターナル セラピューティック インコーポレイテッドＯｎｃｔｅｒｎａｌ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． インドール類似体及びその使用
KR102282794B1 (ko) 2016-07-29 2021-07-27 온크터널 테라퓨틱스, 인코포레이티드. 인돌리논 화합물의 용도
CN110099685A (zh) * 2016-10-20 2019-08-06 赛尔基因光迪斯研究公司 溴结构域抑制剂
JP2021527136A (ja) 2018-06-13 2021-10-11 ディブリー・アーゲー 縮合トリアゼピン誘導体の調製及びｂｅｔ阻害剤としてのその使用
CN108743591A (zh) * 2018-07-17 2018-11-06 苏州大学 用于治疗癌症的药物组合物及其应用
BR112023025562A2 (pt) 2021-06-08 2024-02-20 Poseidon Innovation Llc Compostos anticâncer
WO2023229535A1 (en) 2022-05-27 2023-11-30 Engine Biosciences Pte. Ltd. Bet polypeptide therapeutic agents for generating synthetic lethality in tumors
CN116098870B (zh) * 2023-04-10 2023-07-25 上海赛默罗生物科技有限公司 α5-GABAA受体调节剂的固体分散体及其制备方法

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