KR20160052585A - 항-tl1a 치료를 위한 시스템, 장치 및 방법 - Google Patents

항-tl1a 치료를 위한 시스템, 장치 및 방법 Download PDF

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KR20160052585A
KR20160052585A KR1020167007354A KR20167007354A KR20160052585A KR 20160052585 A KR20160052585 A KR 20160052585A KR 1020167007354 A KR1020167007354 A KR 1020167007354A KR 20167007354 A KR20167007354 A KR 20167007354A KR 20160052585 A KR20160052585 A KR 20160052585A
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tl1a
subject
sample
expression
disease
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스티븐 알. 타간
레베카 곤스키
리차드 딤
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세다르스-신나이 메디칼 센터
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KR1020167007354A 2013-09-06 2014-09-05 항-tl1a 치료를 위한 시스템, 장치 및 방법 Withdrawn KR20160052585A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361874487P 2013-09-06 2013-09-06
US61/874,487 2013-09-06
PCT/US2014/054425 WO2015035261A1 (en) 2013-09-06 2014-09-05 Systems, devices and methods for anti-tl1a therapy

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US (1) US20160208329A1 (https=)
EP (1) EP3041580A4 (https=)
JP (1) JP2016536002A (https=)
KR (1) KR20160052585A (https=)
CN (1) CN105636648A (https=)
AU (1) AU2014317991A1 (https=)
CA (1) CA2922381A1 (https=)
IL (1) IL244427A0 (https=)
MX (1) MX2016002879A (https=)
WO (1) WO2015035261A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US10633449B2 (en) 2013-03-27 2020-04-28 Cedars-Sinai Medical Center Treatment and reversal of fibrosis and inflammation by inhibition of the TL1A-DR3 signaling pathway
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
US11236393B2 (en) 2008-11-26 2022-02-01 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
US12618111B2 (en) 2021-10-28 2026-05-05 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2

Families Citing this family (17)

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Publication number Priority date Publication date Assignee Title
KR101982899B1 (ko) 2011-09-30 2019-05-27 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 ＴＬ1ａ에 대한 항체 및 그의 용도
JP6692748B2 (ja) * 2013-09-26 2020-05-13 ナショナル ユニヴァーシティー オブ シンガポール リゾホスファチジルコリンの足場を利用する組成物及び方法
US20170246259A1 (en) * 2014-09-10 2017-08-31 Georgetown University Compositions and Methods of Using Interleukin-4 Induced Gene 1 (IL-4I1)
JP2018522533A (ja) * 2015-05-15 2018-08-16 シーダーズ—シナイ メディカル センター 炎症性腸疾患を処置するためのモデル、方法および組成物
TWI703158B (zh) 2015-09-18 2020-09-01 美商希佛隆公司 特異性結合tl1a之抗體
US10345302B2 (en) * 2017-02-19 2019-07-09 Sheng-He Huang Circulating astrocytes and MFSD2A as biomarkers
CN106885902B (zh) * 2017-03-03 2018-02-27 四川大学华西第二医院 以ncam‑1为检测指标的金标试剂盒及其制备方法和应用
CN109954000B (zh) * 2017-12-22 2021-02-23 中国农业大学 驴乳在制备食品或者药物中的用途、治疗溃疡性结肠炎的食品和药物
WO2020112890A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
US12448651B2 (en) 2018-12-12 2025-10-21 Hadasit Medical Research Services And Development Ltd. Markers of disease prognosis in multiple sclerosis
CA3180632A1 (en) * 2020-06-03 2021-12-09 Cedars-Sinai Medical Center Methods and systems for measuring post-operative disease recurrence
BR112022025667A2 (pt) * 2020-06-26 2023-03-07 Pfizer Métodos de tratamento da doença inflamatória intestinal com anticorpos tl1a
CN111979311A (zh) * 2020-08-31 2020-11-24 西北大学 肌球蛋白1b作为动脉粥样硬化诊断和治疗靶标的应用
CN112730850B (zh) * 2021-01-22 2022-11-01 广州医科大学附属肿瘤医院 一种肾纤维化生物标志物及其应用
CN115785277B (zh) * 2022-09-09 2023-06-20 上海百英生物科技股份有限公司 一种抗IL4i1纳米抗体的制备及其应用
CN121843714A (zh) 2023-08-11 2026-04-10 派拉冈医疗公司 Tl1a结合抗体及使用方法
KR20250092108A (ko) * 2023-12-12 2025-06-23 의료법인 성광의료재단 면역치료요법의 치료 반응 예측을 위한 바이오마커 및 이를 이용한 유전자 예측 모델

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US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
WO2005018571A2 (en) * 2003-08-20 2005-03-03 University Of Miami Compositions and methods for treating inflammatory lung disease
AU2006284922B2 (en) * 2005-08-30 2012-01-19 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins
US20090186034A1 (en) * 2006-12-19 2009-07-23 Genetech, Inc. Gene expression markers for inflammatory bowel disease
US9896511B2 (en) * 2007-01-10 2018-02-20 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies
US20110217310A1 (en) * 2007-01-10 2011-09-08 Siegel Richard M Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology
US20100190162A1 (en) * 2007-02-26 2010-07-29 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
US8362218B2 (en) * 2009-04-17 2013-01-29 New York University School Of Medicine Peptides targeting TNF family receptors and antagonizing TNF action, compositions, methods and uses thereof
WO2010144358A1 (en) * 2009-06-08 2010-12-16 Singulex, Inc. Highly sensitive biomarker panels
WO2012161856A1 (en) * 2011-05-20 2012-11-29 Government Of The United States, As Represented By The Secretary, Department Of Health And Human Services Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11236393B2 (en) 2008-11-26 2022-02-01 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
US12084722B2 (en) 2008-11-26 2024-09-10 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
US10633449B2 (en) 2013-03-27 2020-04-28 Cedars-Sinai Medical Center Treatment and reversal of fibrosis and inflammation by inhibition of the TL1A-DR3 signaling pathway
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US11312768B2 (en) 2013-07-19 2022-04-26 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US12269873B2 (en) 2013-07-19 2025-04-08 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
US12618111B2 (en) 2021-10-28 2026-05-05 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2

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IL244427A0 (en) 2016-04-21
EP3041580A1 (en) 2016-07-13
US20160208329A1 (en) 2016-07-21
WO2015035261A1 (en) 2015-03-12
MX2016002879A (es) 2016-08-17
CN105636648A (zh) 2016-06-01
EP3041580A4 (en) 2017-05-03
AU2014317991A1 (en) 2016-03-10
JP2016536002A (ja) 2016-11-24
CA2922381A1 (en) 2015-03-12

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