CN105636648A - 用于抗tl1a疗法的系统、装置和方法 - Google Patents

用于抗tl1a疗法的系统、装置和方法 Download PDF

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CN105636648A
CN105636648A CN201480057198.5A CN201480057198A CN105636648A CN 105636648 A CN105636648 A CN 105636648A CN 201480057198 A CN201480057198 A CN 201480057198A CN 105636648 A CN105636648 A CN 105636648A
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tl1a
expression
disease
experimenter
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S·R·塔尔干
R·葛思凯
R·蒂姆
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Cedars Sinai Medical Center
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CN201480057198.5A 2013-09-06 2014-09-05 用于抗tl1a疗法的系统、装置和方法 Pending CN105636648A (zh)

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US201361874487P 2013-09-06 2013-09-06
US61/874,487 2013-09-06
PCT/US2014/054425 WO2015035261A1 (en) 2013-09-06 2014-09-05 Systems, devices and methods for anti-tl1a therapy

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US (1) US20160208329A1 (https=)
EP (1) EP3041580A4 (https=)
JP (1) JP2016536002A (https=)
KR (1) KR20160052585A (https=)
CN (1) CN105636648A (https=)
AU (1) AU2014317991A1 (https=)
CA (1) CA2922381A1 (https=)
IL (1) IL244427A0 (https=)
MX (1) MX2016002879A (https=)
WO (1) WO2015035261A1 (https=)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105764917A (zh) * 2013-09-26 2016-07-13 新加坡国立大学 利用溶血磷脂酰胆碱支架的组合物和方法
CN106885902A (zh) * 2017-03-03 2017-06-23 四川大学华西第二医院 以ncam‑1为检测指标的金标试剂盒及其制备方法和应用
CN108459164A (zh) * 2017-02-19 2018-08-28 黄胜和 生物标志物在制备用于检测中枢神经系统的试剂中的用途
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
CN109954000A (zh) * 2017-12-22 2019-07-02 中国农业大学 驴乳在制备食品或者药物中的用途、治疗溃疡性结肠炎的食品和药物
US10633449B2 (en) 2013-03-27 2020-04-28 Cedars-Sinai Medical Center Treatment and reversal of fibrosis and inflammation by inhibition of the TL1A-DR3 signaling pathway
CN111979311A (zh) * 2020-08-31 2020-11-24 西北大学 肌球蛋白1b作为动脉粥样硬化诊断和治疗靶标的应用
CN112730850A (zh) * 2021-01-22 2021-04-30 广州医科大学附属肿瘤医院 一种肾纤维化生物标志物及其应用
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
US11236393B2 (en) 2008-11-26 2022-02-01 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
CN115785277A (zh) * 2022-09-09 2023-03-14 上海百英生物科技股份有限公司 一种抗IL4i1纳米抗体的制备及其应用
CN116322762A (zh) * 2020-06-26 2023-06-23 辉瑞公司 用tl1a抗体治疗炎症性肠病的方法
US12618111B2 (en) 2021-10-28 2026-05-05 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2

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KR101982899B1 (ko) 2011-09-30 2019-05-27 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 TL1a에 대한 항체 및 그의 용도
US20170246259A1 (en) * 2014-09-10 2017-08-31 Georgetown University Compositions and Methods of Using Interleukin-4 Induced Gene 1 (IL-4I1)
JP2018522533A (ja) * 2015-05-15 2018-08-16 シーダーズ—シナイ メディカル センター 炎症性腸疾患を処置するためのモデル、方法および組成物
TWI703158B (zh) 2015-09-18 2020-09-01 美商希佛隆公司 特異性結合tl1a之抗體
WO2020112890A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
US12448651B2 (en) 2018-12-12 2025-10-21 Hadasit Medical Research Services And Development Ltd. Markers of disease prognosis in multiple sclerosis
CA3180632A1 (en) * 2020-06-03 2021-12-09 Cedars-Sinai Medical Center Methods and systems for measuring post-operative disease recurrence
CN121843714A (zh) 2023-08-11 2026-04-10 派拉冈医疗公司 Tl1a结合抗体及使用方法
KR20250092108A (ko) * 2023-12-12 2025-06-23 의료법인 성광의료재단 면역치료요법의 치료 반응 예측을 위한 바이오마커 및 이를 이용한 유전자 예측 모델

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US20100190162A1 (en) * 2007-02-26 2010-07-29 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12084722B2 (en) 2008-11-26 2024-09-10 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
US11236393B2 (en) 2008-11-26 2022-02-01 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-TNFα therapy in inflammatory bowel disease
US10633449B2 (en) 2013-03-27 2020-04-28 Cedars-Sinai Medical Center Treatment and reversal of fibrosis and inflammation by inhibition of the TL1A-DR3 signaling pathway
US11312768B2 (en) 2013-07-19 2022-04-26 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
US12269873B2 (en) 2013-07-19 2025-04-08 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
CN105764917A (zh) * 2013-09-26 2016-07-13 新加坡国立大学 利用溶血磷脂酰胆碱支架的组合物和方法
CN105764917B (zh) * 2013-09-26 2021-10-08 新加坡国立大学 利用溶血磷脂酰胆碱支架的组合物和方法
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
CN108459164A (zh) * 2017-02-19 2018-08-28 黄胜和 生物标志物在制备用于检测中枢神经系统的试剂中的用途
CN108459164B (zh) * 2017-02-19 2023-01-17 广州美链生物科技有限公司 生物标志物在制备用于检测中枢神经系统的试剂中的用途
CN106885902A (zh) * 2017-03-03 2017-06-23 四川大学华西第二医院 以ncam‑1为检测指标的金标试剂盒及其制备方法和应用
CN109954000A (zh) * 2017-12-22 2019-07-02 中国农业大学 驴乳在制备食品或者药物中的用途、治疗溃疡性结肠炎的食品和药物
CN109954000B (zh) * 2017-12-22 2021-02-23 中国农业大学 驴乳在制备食品或者药物中的用途、治疗溃疡性结肠炎的食品和药物
CN116322762A (zh) * 2020-06-26 2023-06-23 辉瑞公司 用tl1a抗体治疗炎症性肠病的方法
CN111979311A (zh) * 2020-08-31 2020-11-24 西北大学 肌球蛋白1b作为动脉粥样硬化诊断和治疗靶标的应用
CN112730850A (zh) * 2021-01-22 2021-04-30 广州医科大学附属肿瘤医院 一种肾纤维化生物标志物及其应用
US12618111B2 (en) 2021-10-28 2026-05-05 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
CN115785277A (zh) * 2022-09-09 2023-03-14 上海百英生物科技股份有限公司 一种抗IL4i1纳米抗体的制备及其应用

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MX2016002879A (es) 2016-08-17
KR20160052585A (ko) 2016-05-12
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CA2922381A1 (en) 2015-03-12

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