KR20160029079A - Glp-1 유사 펩티드의 유도체 및 그것의 사용 - Google Patents
Glp-1 유사 펩티드의 유도체 및 그것의 사용 Download PDFInfo
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- KR20160029079A KR20160029079A KR1020167002151A KR20167002151A KR20160029079A KR 20160029079 A KR20160029079 A KR 20160029079A KR 1020167002151 A KR1020167002151 A KR 1020167002151A KR 20167002151 A KR20167002151 A KR 20167002151A KR 20160029079 A KR20160029079 A KR 20160029079A
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| EP13175094.5 | 2013-07-04 | ||
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| US201361845646P | 2013-07-12 | 2013-07-12 | |
| US61/845,646 | 2013-07-12 | ||
| PCT/EP2014/064033 WO2015000942A1 (en) | 2013-07-04 | 2014-07-02 | Derivatives of glp-1 like peptides, and uses thereof |
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| KR20160029079A true KR20160029079A (ko) | 2016-03-14 |
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| EP (1) | EP3016975B1 (https=) |
| JP (2) | JP6139712B2 (https=) |
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| CA (1) | CA2916311A1 (https=) |
| MX (1) | MX2015016875A (https=) |
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| KR20160021183A (ko) | 2013-06-20 | 2016-02-24 | 노보 노르디스크 에이/에스 | Glp-1 유도체 및 그것의 용도 |
| WO2015000942A1 (en) * | 2013-07-04 | 2015-01-08 | Novo Nordisk A/S | Derivatives of glp-1 like peptides, and uses thereof |
| JP6730278B2 (ja) | 2014-11-27 | 2020-07-29 | ノヴォ ノルディスク アー／エス | Ｇｌｐ−１誘導体及びその使用 |
| WO2016097108A1 (en) | 2014-12-17 | 2016-06-23 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| AU2016270373A1 (en) | 2015-06-05 | 2018-01-04 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of demyelinating diseases |
| CN108697768B (zh) | 2015-12-23 | 2022-07-22 | 约翰霍普金斯大学 | 长效glp-1r激动剂作为神经系统病状和神经退行性病状的治疗方法 |
| WO2017149070A1 (en) | 2016-03-03 | 2017-09-08 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| MA46780A (fr) | 2016-11-07 | 2019-09-11 | Novo Nordisk As | Esters à dchbs actif de composés peg et leur utilisation |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| CN108976147B (zh) * | 2017-05-31 | 2021-02-12 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
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| EP3655427A1 (en) | 2017-07-19 | 2020-05-27 | Novo Nordisk A/S | Bifunctional compounds |
| HRP20240485T1 (hr) | 2017-08-24 | 2024-07-05 | Novo Nordisk A/S | Pripravci glp-1 i njihova upotreba |
| JP7359358B2 (ja) * | 2017-11-30 | 2023-10-11 | グリアファーム エスエー | 神経疾患の予防及び治療に使用するためのポリケチド化合物及びその誘導体 |
| RS63523B1 (sr) | 2018-04-05 | 2022-09-30 | Sun Pharmaceutical Ind Ltd | Novi glp-1 analozi |
| WO2019200594A1 (zh) | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
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| CN115260313B (zh) | 2019-12-31 | 2023-07-18 | 北京质肽生物医药科技有限公司 | Glp-1和gdf15的融合蛋白以及其缀合物 |
| CN115322794B (zh) | 2020-01-11 | 2025-09-19 | 北京质肽生物医药科技有限公司 | Glp-1和fgf21的融合蛋白的缀合物 |
| PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
| CN114729060B (zh) | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| CN116490212A (zh) * | 2020-11-06 | 2023-07-25 | 诺和诺德股份有限公司 | Glp-1前药及其用途 |
| CN114685644A (zh) * | 2020-12-29 | 2022-07-01 | 苏州康宁杰瑞生物科技有限公司 | 一种人glp-1多肽变体及其应用 |
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| JP2026502943A (ja) | 2022-12-30 | 2026-01-27 | アルギファルマ エーエス | 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法 |
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| JP2002512175A (ja) * | 1998-02-27 | 2002-04-23 | ノボ ノルディスク アクティーゼルスカブ | Ｇｌｐ−１類似体の誘導体類 |
| EP1956000B1 (en) | 1999-03-17 | 2016-10-05 | Novo Nordisk A/S | Acylating agents useful for acylating peptides |
| EP1076066A1 (en) * | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| EP1239871A1 (en) * | 1999-11-12 | 2002-09-18 | Novo Nordisk A/S | Use of glp-1 agonists for the inhibition of beta cell degeneration |
| GB0020551D0 (en) | 2000-08-22 | 2000-10-11 | Birkett David | Sprinkler system |
| EP1605897B1 (en) | 2003-03-19 | 2012-07-25 | Eli Lilly And Company | Polyethelene glycol link glp-1 compounds |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| PT1881850E (pt) | 2005-05-13 | 2010-11-26 | Lilly Co Eli | Compostos peguilados de glp-1 |
| US20110144010A1 (en) | 2007-06-01 | 2011-06-16 | Novo Nordisk A/S | Spontaneously Dispersible Preconcentrates Including a Peptide Drug in a Solid or Semisolid Carrier |
| US20100261637A1 (en) | 2007-09-05 | 2010-10-14 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| EP2190872B1 (en) | 2007-09-05 | 2018-03-14 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| EP2398822B1 (en) | 2009-02-19 | 2013-01-02 | Novo Nordisk A/S | Modification of factor viii |
| EP2512518A1 (en) | 2009-12-16 | 2012-10-24 | Novo Nordisk A/S | Glp-1 receptor agonist compounds with a modified n-terminus |
| EP2637698B1 (en) | 2010-11-09 | 2022-04-20 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
| RU2602601C2 (ru) * | 2011-04-12 | 2016-11-20 | Ново Нордиск А/С | Дважды ацилированные производные glp-1 |
| WO2015000942A1 (en) * | 2013-07-04 | 2015-01-08 | Novo Nordisk A/S | Derivatives of glp-1 like peptides, and uses thereof |
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| JP6687557B2 (ja) | 2020-04-22 |
| AR096789A1 (es) | 2016-02-03 |
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| JP2017105819A (ja) | 2017-06-15 |
| CN105377884A (zh) | 2016-03-02 |
| AU2014286234A1 (en) | 2015-12-17 |
| CN105377884B (zh) | 2021-07-20 |
| WO2015000942A1 (en) | 2015-01-08 |
| BR112015032875A2 (pt) | 2017-11-07 |
| CA2916311A1 (en) | 2015-01-08 |
| EP3016975B1 (en) | 2019-01-16 |
| US10010614B2 (en) | 2018-07-03 |
| JP2016528163A (ja) | 2016-09-15 |
| US20150011462A1 (en) | 2015-01-08 |
| US9498534B2 (en) | 2016-11-22 |
| JP6139712B2 (ja) | 2017-05-31 |
| MX2015016875A (es) | 2016-04-07 |
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