KR20160019469A - 코노톡신 펩티드, 제약 조성물 및 그의 용도 - Google Patents

코노톡신 펩티드, 제약 조성물 및 그의 용도 Download PDF

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Publication number
KR20160019469A
KR20160019469A KR1020157036731A KR20157036731A KR20160019469A KR 20160019469 A KR20160019469 A KR 20160019469A KR 1020157036731 A KR1020157036731 A KR 1020157036731A KR 20157036731 A KR20157036731 A KR 20157036731A KR 20160019469 A KR20160019469 A KR 20160019469A
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pain
seq
conotoxin
tyr
conotoxin peptide
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Korean (ko)
Inventor
제이. 마이클 맥킨토시
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더 유니버시티 오브 유타 리서치 파운데이션
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Publication of KR20160019469A publication Critical patent/KR20160019469A/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020157036731A 2013-05-31 2014-05-30 코노톡신 펩티드, 제약 조성물 및 그의 용도 Ceased KR20160019469A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361829633P 2013-05-31 2013-05-31
US61/829,633 2013-05-31
US201361843135P 2013-07-05 2013-07-05
US61/843,135 2013-07-05
PCT/US2014/040374 WO2014194284A1 (en) 2013-05-31 2014-05-30 Conotoxin peptides, pharmaceutical compositions and uses thereof

Publications (1)

Publication Number Publication Date
KR20160019469A true KR20160019469A (ko) 2016-02-19

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ID=51989449

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KR1020157036731A Ceased KR20160019469A (ko) 2013-05-31 2014-05-30 코노톡신 펩티드, 제약 조성물 및 그의 용도

Country Status (11)

Country Link
US (1) US10633417B2 (enExample)
EP (1) EP3003344B1 (enExample)
JP (1) JP6681826B2 (enExample)
KR (1) KR20160019469A (enExample)
CN (1) CN105377286B (enExample)
AU (1) AU2014273883B9 (enExample)
CA (1) CA2913993A1 (enExample)
HK (1) HK1221425A1 (enExample)
MX (1) MX367858B (enExample)
TW (1) TWI686205B (enExample)
WO (1) WO2014194284A1 (enExample)

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TWI708790B (zh) * 2014-11-07 2020-11-01 美商奇尼塔慢性疼痛有限責任公司 芋螺毒素(conotoxin)肽之修飾及用途
CN105985410B (zh) * 2015-02-16 2019-11-29 海南大学 芋螺肽、其药物组合物及用途
US10947274B1 (en) * 2018-05-01 2021-03-16 University Of Utah Research Foundation Synthetic analgesic peptides of RgIA analogs
US11612661B2 (en) 2019-01-04 2023-03-28 Kineta Chronic Pain, Llc Conotoxin peptide analogs and uses for the treatment of pain and inflammatory conditions
CN113493502B (zh) * 2020-04-01 2023-09-12 广西大学 α-芋螺毒素肽TxIE、其药物组合物及用途
KR20230031884A (ko) * 2020-06-03 2023-03-07 유타대학연구재단 형태적으로 제약된 α-RGIA 유사체
CN114805488B (zh) * 2021-01-29 2023-05-30 李威 一种靶向神经元烟碱型乙酰胆碱受体的新型多肽分子nAChR_BP及其应用
US20240269228A1 (en) * 2021-06-03 2024-08-15 University Of Utah Research Foundation Selective penicillamine substitution enables development of a potent analgesic peptide that acts through a non-opioid based mechanism

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Also Published As

Publication number Publication date
CN105377286B (zh) 2021-07-02
AU2014273883A1 (en) 2015-12-17
US10633417B2 (en) 2020-04-28
CA2913993A1 (en) 2014-12-04
TW201503897A (zh) 2015-02-01
US20160122388A1 (en) 2016-05-05
WO2014194284A1 (en) 2014-12-04
EP3003344B1 (en) 2020-11-25
JP6681826B2 (ja) 2020-04-15
AU2014273883B2 (en) 2019-11-07
JP2016520620A (ja) 2016-07-14
EP3003344A4 (en) 2016-12-28
MX2015016492A (es) 2016-07-14
HK1221425A1 (zh) 2017-06-02
AU2014273883B9 (en) 2020-06-18
TWI686205B (zh) 2020-03-01
CN105377286A (zh) 2016-03-02
EP3003344A1 (en) 2016-04-13
MX367858B (es) 2019-09-09

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