KR20150091434A - 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 - Google Patents
다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 Download PDFInfo
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- KR20150091434A KR20150091434A KR1020157020493A KR20157020493A KR20150091434A KR 20150091434 A KR20150091434 A KR 20150091434A KR 1020157020493 A KR1020157020493 A KR 1020157020493A KR 20157020493 A KR20157020493 A KR 20157020493A KR 20150091434 A KR20150091434 A KR 20150091434A
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- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07—ORGANIC CHEMISTRY
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- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/14—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of rings other than six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/28—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
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Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/830,733 US8101799B2 (en) | 2005-07-21 | 2007-07-30 | Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK |
US11/830,733 | 2007-07-30 | ||
US3446608P | 2008-03-06 | 2008-03-06 | |
US3446408P | 2008-03-06 | 2008-03-06 | |
US61/034,466 | 2008-03-06 | ||
US61/034,464 | 2008-03-06 | ||
US4488608P | 2008-04-14 | 2008-04-14 | |
US61/044,886 | 2008-04-14 | ||
PCT/US2008/071392 WO2009018233A1 (en) | 2007-07-30 | 2008-07-28 | Derivatives of n-(arylamino) sulfonamides including polymorphs as inhibitors of mek as well as compositions, methods of use and methods for preparing the same |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020107004742A Division KR20100092424A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20150091434A true KR20150091434A (ko) | 2015-08-10 |
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Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020147017261A KR20140098185A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
KR1020157020493A KR20150091434A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
KR1020107004742A KR20100092424A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020147017261A KR20140098185A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020107004742A KR20100092424A (ko) | 2007-07-30 | 2008-07-28 | 다형체를 포함하는, mek의 억제제로서의 n-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
Country Status (23)
Country | Link |
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EP (1) | EP2184984A4 (ja) |
JP (3) | JP2010535232A (ja) |
KR (3) | KR20140098185A (ja) |
CN (2) | CN103479604B (ja) |
AP (1) | AP2817A (ja) |
AU (2) | AU2008282338B2 (ja) |
BR (1) | BRPI0815659A2 (ja) |
CA (1) | CA2693390C (ja) |
CO (1) | CO6470808A2 (ja) |
CR (1) | CR11244A (ja) |
DO (1) | DOP2010000045A (ja) |
EA (2) | EA020624B1 (ja) |
EC (1) | ECSP109910A (ja) |
HK (1) | HK1147396A1 (ja) |
HN (1) | HN2010000203A (ja) |
IL (1) | IL203296A (ja) |
MA (1) | MA31881B1 (ja) |
MX (1) | MX2010001244A (ja) |
NZ (1) | NZ582929A (ja) |
PH (1) | PH12015501914A1 (ja) |
SV (1) | SV2010003469A (ja) |
TN (1) | TN2010000049A1 (ja) |
WO (1) | WO2009018233A1 (ja) |
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CN102020651B (zh) | 2010-11-02 | 2012-07-18 | 北京赛林泰医药技术有限公司 | 6-芳基氨基吡啶酮甲酰胺mek抑制剂 |
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CN109456272A (zh) * | 2012-10-19 | 2019-03-12 | 阵列生物制药公司 | Mek抑制剂的制备和包含mek抑制剂的制剂 |
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PL1912636T3 (pl) * | 2005-07-21 | 2015-02-27 | Ardea Biosciences Inc | N-(aryloamino)sulfonamidowe inhibitory mek |
JP2007099763A (ja) * | 2005-09-08 | 2007-04-19 | Toyama Chem Co Ltd | ピペラシリンナトリウム・1水和物の新規な結晶及びその製造方法 |
TW200800150A (en) * | 2005-12-21 | 2008-01-01 | Organon Nv | Compounds with medicinal effects due to interaction with the glucocorticoid receptor |
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