KR20150082688A - 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 - Google Patents

미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 Download PDF

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KR20150082688A
KR20150082688A KR1020157017377A KR20157017377A KR20150082688A KR 20150082688 A KR20150082688 A KR 20150082688A KR 1020157017377 A KR1020157017377 A KR 1020157017377A KR 20157017377 A KR20157017377 A KR 20157017377A KR 20150082688 A KR20150082688 A KR 20150082688A
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cell
cells
tumor
antigen
dendritic cells
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Korean (ko)
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알톤 엘. 보인톤
말닉스 엘. 보쉬
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노쓰웨스트 바이오써라퓨틱스, 인크.
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KR1020157017377A 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 Ceased KR20150082688A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74888505P 2005-12-08 2005-12-08
US60/748,885 2005-12-08
PCT/US2006/047083 WO2007067782A2 (en) 2005-12-08 2006-12-08 Compositions and methods for inducing the activation of immature monocytic dendritic cells

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KR1020087016423A Division KR20080109717A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한조성물 및 방법

Related Child Applications (1)

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KR1020187011878A Division KR20180049169A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법

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KR20150082688A true KR20150082688A (ko) 2015-07-15

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KR1020227026051A Ceased KR20220113543A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020217002605A Ceased KR20210013327A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020087016423A Ceased KR20080109717A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한조성물 및 방법
KR1020187011878A Ceased KR20180049169A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020157017377A Ceased KR20150082688A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020237044465A Ceased KR20240005984A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법

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KR1020227026051A Ceased KR20220113543A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020217002605A Ceased KR20210013327A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법
KR1020087016423A Ceased KR20080109717A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한조성물 및 방법
KR1020187011878A Ceased KR20180049169A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법

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KR1020237044465A Ceased KR20240005984A (ko) 2005-12-08 2006-12-08 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법

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Country Link
US (2) US20080254537A1 (enExample)
EP (3) EP1957634A4 (enExample)
JP (7) JP5954918B2 (enExample)
KR (6) KR20220113543A (enExample)
CN (2) CN101336291A (enExample)
AR (1) AR056851A1 (enExample)
AU (1) AU2006321794A1 (enExample)
BR (1) BRPI0619499A2 (enExample)
CA (1) CA2632263C (enExample)
CR (1) CR10048A (enExample)
IL (2) IL191930A (enExample)
RU (1) RU2008122550A (enExample)
TW (1) TW200800252A (enExample)
WO (1) WO2007067782A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210141411A (ko) * 2020-05-15 2021-11-23 서울대학교산학협력단 지방조직에서 분리된 기질혈관분획의 수지상세포의 활성화 기능을 이용한 면역 반응 증진용 조성물

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002232560A1 (en) 2000-10-27 2002-05-06 Immuno-Rx, Inc Vaccine immunotherapy for immune suppressed patients
US20070025958A1 (en) 2000-10-27 2007-02-01 Hadden John W Vaccine immunotherapy
WO2009137238A2 (en) * 2008-04-14 2009-11-12 Irx Therapeutics, Inc. Irx-2 modified manufacturing process
WO2010065876A2 (en) 2008-12-06 2010-06-10 The Board Of Regents Of The University Of Texas System Methods and compositions related to th-1 dendritic cells
JP2012523379A (ja) * 2009-04-09 2012-10-04 ザ ユニバーシティー オブ メルボルン 免疫原性組成物およびその使用
ES2679043T3 (es) 2009-05-15 2018-08-21 Irx Therapeutics, Inc. Inmunoterapia de vacuna
CN102596234B (zh) * 2009-07-24 2016-11-16 罗得岛医院 针对表达天冬酰胺酰-β-羟化酶的肿瘤的树突细胞疫苗
WO2011028257A1 (en) * 2009-08-24 2011-03-10 The Trustees Of Columbia University In The City Of New York Assay for determining health of cd8+ t cells
US8815229B2 (en) 2009-10-12 2014-08-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Granulysin in immunotherapy
AU2010328197B2 (en) 2009-12-08 2015-07-16 Irx Therapeutics, Inc. Method of reversing immune suppression of Langerhans cells
US9476029B2 (en) * 2010-11-13 2016-10-25 Lung-Ji Chang Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells
NL2009102C2 (en) * 2012-07-02 2014-01-06 Dcprime B V Method for dc-loading.
TWI503414B (zh) * 2012-07-05 2015-10-11 Fullhope Biomedical Co Ltd 一種製備專一性t細胞之配方、方法及其配方製備方法
AU2020203845C1 (en) * 2012-09-06 2022-08-11 Orbis Health Solutions, Llc Tumor lysate loaded particles
US9744193B2 (en) * 2012-09-06 2017-08-29 Orbis Health Solutions Llc Tumor lysate loaded particles
CN104981258B (zh) 2012-12-12 2017-10-20 奥比思健康解决方案有限责任公司 用于组织再生的组合物、其制备方法及其用途
DK2788474T3 (en) * 2012-12-18 2015-09-28 Immunicum Ab CO differentiation of monocytes FROM ALLOGENEIC DONORS
CN112891522A (zh) * 2013-09-05 2021-06-04 奥比思健康解决方案有限责任公司 装载了肿瘤裂解物的微粒
CN103756960A (zh) * 2013-12-04 2014-04-30 深圳市合一康生物科技有限公司 一种高毒性、高增值能力的人d-cik细胞的专用试剂盒
CN103784950A (zh) * 2014-01-22 2014-05-14 北京弘润源生物技术有限公司 乳腺癌特异抗原表位多肽负载的树突状细胞疫苗制备及其试剂盒
US10166195B2 (en) 2014-03-05 2019-01-01 Orbis Health Solutions, Llc Vaccine delivery systems using yeast cell wall particles
CN103800897B (zh) * 2014-03-12 2017-03-22 李金珍 一种肿瘤特异抗原表位多肽负载的树突状细胞疫苗制备方法及其试剂盒
WO2015199402A1 (ko) * 2014-06-23 2015-12-30 제이더블유크레아젠 주식회사 특정 유전자 발현이 증가된 수지상세포의 제조방법 및 이를 이용하여 제조된 수지상세포를 포함하는 자가면역질환 치료 또는 예방용 조성물
WO2016145578A1 (en) * 2015-03-13 2016-09-22 Syz Cell Therapy Co. Methods of cancer treatment using activated t cells
AU2016323066B2 (en) * 2015-09-15 2023-04-27 Northwest Biotherapeutics, Inc Methods relating to activated dendritic cell compositions and immunotherapeutic treatments for subjects with advanced cancers
CN105647867A (zh) * 2016-02-28 2016-06-08 深圳爱生再生医学科技有限公司 诱导树突状细胞成熟的方法和树突状细胞
CN105670994A (zh) * 2016-02-28 2016-06-15 深圳爱生再生医学科技有限公司 Dc诱导剂及其应用
JP7185530B2 (ja) 2016-06-13 2022-12-07 トルク セラピューティクス, インコーポレイテッド 免疫細胞機能を促進するための方法および組成物
US20190241871A1 (en) * 2016-09-01 2019-08-08 Riken Immune Regenerative Medicine Inc. Method for manufacturing natural killer t (nkt) cell - stimulating dendritic cell, method for manufacturing cell composition containing the nkt cell stimulating dendritic cell and nkt cell, and cell composition containing thereof
WO2018061006A1 (en) * 2016-09-29 2018-04-05 Hadasit Medical Research Services And Development Ltd. Dendritic cell preparations, compositions thereof and methods of using same
CA3074826A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. Therapeutic protein compositions and methods of making and using the same
CN109957548B (zh) * 2017-12-26 2022-03-18 上海尚泰生物技术有限公司 一种基因修饰的树突状细胞疫苗
JP6881333B2 (ja) * 2018-01-29 2021-06-02 株式会社三洋物産 遊技機
JP6881332B2 (ja) * 2018-01-29 2021-06-02 株式会社三洋物産 遊技機
JP6881331B2 (ja) * 2018-01-29 2021-06-02 株式会社三洋物産 遊技機
WO2019183924A1 (en) 2018-03-30 2019-10-03 Syz Cell Therapy Co. Improved multiple antigen specific cell therapy methods
WO2020032782A1 (ko) * 2018-08-10 2020-02-13 주식회사 유틸렉스 암항원 특이적 cd8+ t 세포의 제조 및 동결보존 방법
CN110106145B (zh) * 2019-06-12 2021-02-12 蓝莲(杭州)生物科技有限公司 一种未成熟树突状细胞培养液及其未成熟树突状细胞的制备方法
KR102818249B1 (ko) * 2021-11-11 2025-06-10 의료법인 명지의료재단 Kras 특이적 활성화 t 세포 유도용 항원 조성물을 이용한 항원 특이적 t 세포 유도방법
KR102753583B1 (ko) * 2021-11-11 2025-01-10 의료법인 명지의료재단 Kras 특이적 활성화 t 세포 유도용 항원 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE260971T1 (de) 1992-04-01 2004-03-15 Univ Rockefeller Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung
US5788963A (en) 1995-07-31 1998-08-04 Pacific Northwest Cancer Foundation Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy
US7659119B2 (en) 1996-02-12 2010-02-09 Argos Therapeutics, Inc. Method and compositions for obtaining mature dendritic cells
WO1998046083A1 (en) * 1997-04-17 1998-10-22 The Regents Of The University Of California Use of lentiviral vectors for antigen presentation in dendritic cells
US6558951B1 (en) 1999-02-11 2003-05-06 3M Innovative Properties Company Maturation of dendritic cells with immune response modifying compounds
WO2003010292A2 (en) 2001-07-25 2003-02-06 Northwest Biotherapeutics, Inc. Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors
ES2766299T3 (es) * 2001-09-06 2020-06-12 Northwest Biotherapeutics Inc Composiciones y procedimientos para la activación linfocitaria de células dendríticas monocíticas y células T para generar una respuesta Th-1
RU2328317C2 (ru) 2002-06-19 2008-07-10 Норсуэст Байотерапьютикс, Инк Устройство для фильтрации тангенциального потока и способы обогащения лейкоцитов
AT412145B (de) * 2002-09-13 2004-10-25 Forsch Krebskranke Kinder Verfahren zur herstellung eines zellulären immuntherapeutikums auf basis von il-12-freisetzenden dendritischen zellen
JP4762887B2 (ja) * 2003-02-27 2011-08-31 ノースウエスト バイオセラピューティクス,インコーポレイティド 付加的なサイトカインの非存在下でgm−csfを用いる単球樹状前駆細胞からの樹状細胞の産生

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210141411A (ko) * 2020-05-15 2021-11-23 서울대학교산학협력단 지방조직에서 분리된 기질혈관분획의 수지상세포의 활성화 기능을 이용한 면역 반응 증진용 조성물

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