KR20140127307A - 섬유성 질병을 치료하기 위한 pi3k 억제제 - Google Patents
섬유성 질병을 치료하기 위한 pi3k 억제제 Download PDFInfo
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- KR20140127307A KR20140127307A KR20147024991A KR20147024991A KR20140127307A KR 20140127307 A KR20140127307 A KR 20140127307A KR 20147024991 A KR20147024991 A KR 20147024991A KR 20147024991 A KR20147024991 A KR 20147024991A KR 20140127307 A KR20140127307 A KR 20140127307A
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- Prior art keywords
- pharmaceutically acceptable
- pyridazinyl
- methyloxy
- pyridinyl
- benzenesulfonamide
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000080 wetting agent Substances 0.000 description 1
- 239000012130 whole-cell lysate Substances 0.000 description 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261595293P | 2012-02-06 | 2012-02-06 | |
| US61/595,293 | 2012-02-06 | ||
| US201261702854P | 2012-09-19 | 2012-09-19 | |
| US61/702,854 | 2012-09-19 | ||
| PCT/EP2013/052112 WO2013117503A2 (en) | 2012-02-06 | 2013-02-04 | Novel use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20140127307A true KR20140127307A (ko) | 2014-11-03 |
Family
ID=47633093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20147024991A Withdrawn KR20140127307A (ko) | 2012-02-06 | 2013-02-04 | 섬유성 질병을 치료하기 위한 pi3k 억제제 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20150051215A1 (enExample) |
| EP (1) | EP2812002A2 (enExample) |
| JP (1) | JP2015509483A (enExample) |
| KR (1) | KR20140127307A (enExample) |
| CN (1) | CN104093408A (enExample) |
| AU (1) | AU2013218148A1 (enExample) |
| BR (1) | BR112014018106A2 (enExample) |
| CA (1) | CA2861521A1 (enExample) |
| RU (1) | RU2014128387A (enExample) |
| WO (1) | WO2013117503A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190269675A1 (en) | 2014-01-28 | 2019-09-05 | Buck Institute for Research and Aging | Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agents |
| US20170216286A1 (en) | 2014-01-28 | 2017-08-03 | Mayo Foundation For Medical Education And Research | Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoid |
| CA2939121C (en) | 2014-01-28 | 2020-11-24 | Mayo Foundation For Medical Education And Research | Effective treatment of osteoarthritis, pulmonary disease, ophthalmic disease, and atherosclerosis by removing senescent cells at the site of the disease |
| AU2016301113B2 (en) | 2015-07-30 | 2019-10-03 | Monash University | Fibrotic treatment |
| JP6419097B2 (ja) * | 2016-01-14 | 2018-11-07 | 学校法人東京農業大学 | ヤマノイモ属植物からのディオスコリンの製造方法 |
| EP3608313B1 (en) | 2017-04-01 | 2024-07-31 | Zhengzhou University | 15-idene-14-deoxy-11,12-dehydroandrographolide derivative and application thereof in preparing anti-fibrosis drugs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| UY31137A1 (es) * | 2007-06-14 | 2009-01-05 | Smithkline Beecham Corp | Derivados de quinazolina como inhibidores de la pi3 quinasa |
-
2013
- 2013-02-04 US US14/376,664 patent/US20150051215A1/en not_active Abandoned
- 2013-02-04 CA CA2861521A patent/CA2861521A1/en not_active Abandoned
- 2013-02-04 KR KR20147024991A patent/KR20140127307A/ko not_active Withdrawn
- 2013-02-04 BR BR112014018106A patent/BR112014018106A2/pt not_active IP Right Cessation
- 2013-02-04 EP EP13702473.3A patent/EP2812002A2/en not_active Withdrawn
- 2013-02-04 RU RU2014128387A patent/RU2014128387A/ru unknown
- 2013-02-04 AU AU2013218148A patent/AU2013218148A1/en not_active Abandoned
- 2013-02-04 WO PCT/EP2013/052112 patent/WO2013117503A2/en not_active Ceased
- 2013-02-04 JP JP2014555239A patent/JP2015509483A/ja active Pending
- 2013-02-04 CN CN201380008089.XA patent/CN104093408A/zh active Pending
-
2015
- 2015-11-18 US US14/944,531 patent/US20160067247A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150051215A1 (en) | 2015-02-19 |
| US20160067247A1 (en) | 2016-03-10 |
| RU2014128387A (ru) | 2016-03-27 |
| WO2013117503A3 (en) | 2013-10-03 |
| BR112014018106A2 (pt) | 2017-06-27 |
| EP2812002A2 (en) | 2014-12-17 |
| AU2013218148A1 (en) | 2014-07-24 |
| WO2013117503A2 (en) | 2013-08-15 |
| CN104093408A (zh) | 2014-10-08 |
| CA2861521A1 (en) | 2013-08-15 |
| JP2015509483A (ja) | 2015-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20140904 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |