KR20140103723A - Fragrance composition having sound sleep effect - Google Patents

Abstract

The present invention relates to a fragrance composition having a sleeping effect by containing natural oil like eucalyptus leaf oil and cedarwood oil. More specifically, the fragrance composition according to the present invention contains two or more kinds among eucalyptus leaf oil, cedarwood oil, phenethyl alcohol, methyl dihydrojasmonate, and linalool to use a sleeping effect by each of fragrance combinations to induce a comfortable sleeping condition.

Description

[0001] Fragrance composition having a sleeping effect [0002]

The present invention relates to a perfume composition having a sleeping effect by containing a natural oil such as eucalyptus leaf oil, cedarwood oil and the like. More specifically, the perfume composition according to the present invention contains at least two kinds of eucalyptus leaf oil, cedar wood oil, phenethyl alcohol, methyl dihydro jasmonate and linolul, thereby utilizing the sleeping effect of each perfume combination To thereby induce a comfortable sleeping.

Sleep is an active state in which an important physiological function is operated by the brain for the brain. It is an adaptive behavior maintained by a high physiological function, not a simple downtime, and is a biologic defense technique. In particular, for people with developed cerebral cortex, the quality of sleep affects the quality of life, so taking a good sleep is very important for improving quality of life.

Korean Patent Laid-Open Publication No. 2012-0065813

Therefore, the present inventors have continued to investigate whether various perfume materials have a sleeping effect. As a result of the study, it was found that a perfume composition using Eucalyptus oil, Cedarwood oil, Phenethyl Alcohol, Methyl dihydro jasmonate and Linalool, And the palatability was shown to be excellent in addition to the palatability. Thus, the present invention was completed.

Accordingly, it is an object of the present invention to provide a perfume composition capable of inducing a good night's sleep.

In order to accomplish the above object, the present invention provides a method for producing an oil composition comprising Eucalyptus oil, Cedarwood oil, Phenethyl Alcohol, Methyl dihydro jasmonate and Linalool Linalool). ≪ / RTI >

The present invention relates to a perfume composition containing eucalyptus leaf oil, cedarwood oil, phenethyl alcohol, methyl dihydro jasmonate and linalool. The perfume composition according to the present invention has an effect of inducing a good sleeping and comfortable sleeping, And cosmetics.

FIG. 1 is a graph showing average values of results of measurement of the surface delay time after using the embodiment or the comparative example.
Fig. 2 shows the results of measuring the water surface efficiency after using the example or the comparative example.
Fig. 3 shows the result of measuring the degree of tension at the time of sleeping compared with the normal water surface after using the example or the comparative example.
FIG. 4 shows the result of measuring the degree of repetition at the time of sleeping in comparison with the normal water surface after using the embodiment or the comparative example.
Figure 5 shows the overall satisfaction with sleep compared to normal sleep after using the example or comparative example.

The present invention relates to a method for the preparation of 2, 3, 4, 5 or 6 selected from the group consisting of Eucalyptus oil, Cedarwood oil, Phenethyl Alcohol, Methyl dihydro jasmonate and Linalool. Wherein the perfume composition contains at least one species of perfume composition. The perfume composition of the present invention is effective for inducing sleeping and comfortable sleeping, and is also excellent in palatability.

Eucalyptus leaf oil used in the present invention is an essential oil obtained from fresh leaves of Eucalyptus globulus and other eucalyptus species and has a strong sterilizing action and is effective as a bath agent to cleanse the skin and to treat skin disorders. It is also effective in relieving stress, relieving stress, and cooling in hot sun-exposed skin. It has been used since the ancient Egyptian era to maintain the youthful skin.

Cedarwood oil is in Pinaceae Cedrus deodara (Cedrus spp.) Or cupressaceae Hawthorn Juniper (Juniperus spp.), In Cypress (Cupressus spp . ) It is a refined oil obtained by distilling leaves and branches of conifers. It gives a refreshing and fragrant woody fragrance and it feels like staying in a moist forest. It is helpful when you are nervous or anxious, when you are feeling depressed, or when you smell at the time of meditation. Disinfection, disinfection, convergence, diuretic, skin softening, tonic, genomic, sterilization, soothing. It is also known to be effective in preventing hair loss and dandruff.

Phenethyl alcohol is an organic substance having a molecular structure of C ₆ H ₅ CH ₂ CH ₂ OH and is found in various flowers such as rose, carnation and geranium, and has a rose scent.

Methyl dihydro jasmonate is an ester of methyl 3-oxo-2-pentylcyclopentane acetic acid and is found in natural products such as jasmine, tea, heliotrope and the like and has a warm flower like jasmine.

Linalool is a chain-like mono terpene alcohol widely present in natural products such as bergamot oil, rosewood oil, and clary sage oil, and has a refreshing floral appearance.

The oil used in the perfume composition of the present invention is not limited in its content and may be appropriately mixed and used.

In addition, the perfume composition of the present invention can provide an optimal sleep inducing effect when all of the above-mentioned five oils are used. In this case, the perfume composition according to the present invention may contain 0.1 to 20% by weight of eucalyptus leaf oil, 0.1 to 20% by weight of cedar wood oil, 0.5 to 50% by weight of phenethyl alcohol, methyl dihydro jasmonate 10 To 50% by weight and linalool 10-30% by weight, and when the content of the oil is out of the above range with respect to the total weight of the composition, the best possible sleeping effect can not be obtained.

The perfume composition according to the present invention may be formulated into a composition for external application for skin such as perfume and cosmetics and may be appropriately selected and blended in order to achieve the desired effect according to the conventional art. May be formulated in an amount of 0.01 to 30% by weight based on the total weight.

The external preparation for skin is not limited in its formulation and may be formulated in any formulation known in the art. Examples of formulations include packs, ointments, lotions, soluble powders, suspensions, emulsions, creams, gels, sprays, papermaking, warnings, patches or water pills.

In the present invention, in order to investigate the sleeping effect of the perfume composition, the EEG, the degree of safety, and the electrocardiogram (EEG) of the sleeping surface were measured to perform a sleeping test and a subjective evaluation of sleep.

As can be seen from the results of the following test examples, by using the fragrances of the present invention, it is confirmed that the sleep efficiency is increased and the surface delay time is shortened from the results of the sleep polygraph. In addition, from the subjective evaluation results after sleeping, it can be confirmed that the decrease of tension, the decrease in the degree of turnover, and the satisfaction of the overall sleep are high.

Hereinafter, the present invention will be described in more detail by way of examples and test examples, but the present invention is not limited to these examples.

[Example] A perfume composition having a sleeping effect

In order to examine the effect of the perfume composition according to the present invention, fragrance compositions (Examples 1 to 4) were prepared according to the composition of Table 1 in consideration of the sleeping effect and palatability, Experiments were conducted.

Sleeping fragrance composition Component name (content;% by weight) Example 1 Example 2 Example 3 Example 4 Eucalyptus leaf oil 50 25 15 10 Cedarwood oil 50 25 15 10 Phenethyl alcohol - 50 35 30 Methyl dihydro jasmonate - - 35 30 Linerul - - - 20 total 100 100 100 100

The perfume composition of Example 1 is a combination of eucalyptus leaf oil and cedar wood oil, which has a fresh and clean wood aroma. The perfume composition of Example 2 is obtained by adding phenethyl alcohol to the perfume composition of Example 1, and has a clear rose-like appearance. The perfume composition of Example 3 is obtained by adding methyl dihydro jasmonate to the perfume composition of Example 2, and has a clean floral appearance. Finally, the perfume composition of Example 4 is obtained by adding linalool to the perfume composition of Example 3,

[Test Example] Measurement of sleep effect of perfume composition

In order to objectively evaluate the effect of the perfume composition according to the present invention, the perfume composition (Examples 1 to 4) prepared in Table 1 was used to measure the middle brain waves, the degree of safety, and the electrocardiogram And subjective assessment of sleep. The concrete method is as follows.

1. Subjects

The study subjects were 20 healthy, 20 to 30 year old women who were not taking drugs and were not blind. The subjects were instructed to refrain from excessive exercise or excessive drinking on the day before the experiment and to refrain from smoking, drinking, drugs and gum intake which could affect the central nervous system and olfactory sense on the day of the experiment. The results of this study are as follows. First, the effects of the sex cycle on the sensory change and the menstrual cycle and mood of women are reported.

2. Experimental Sample

The test samples were prepared in the same manner as in Example 1 except that the fragrance composition (Examples 1 to 4) and Comparative Example 1 (Comparative Example 1), Eucalyptus leaf oil (Comparative Example 2), Cedarwood Oil (Comparative Example 3) Phenethyl alcohol (Comparative Example 4), methyl dihydro jasmonate (Comparative Example 5) and linalool (Comparative Example 6) were used. Sleep surface laboratory showed constant incense, and EEG, safety (EOG), and electrocardiogram (ECG) of sleeping were measured and sleep polygraph was performed.

3. Place of experiment

Experiments were carried out in a sleep laboratory (4.8 m × 3 m × 2.4 m) constructed by the National Institute of Advanced Industrial Science and Technology (AIST). Soundproofing equipment was installed inside the laboratory to exclude the influence of the external environment. The sleep laboratory was kept at constant temperature and humidity, the temperature was 24 ℃, and the humidity was 40%.

4. Measurement method

EEG, safety (EOG) and electrocardiogram (ECG) were measured using a sleep polygraph. Subjective evaluation of sleep was made after completing the experiment on the sleeping feeling of the subject.

5. Procedure

Experiments were carried out in the sleeping polygraphy under the perfume composition conditions of the control examples and the examples. In order to exclude the effect of order on sleep, the subjects were randomly assigned to one of two sleeping laboratories to adjust to the sleep laboratory before the experiment. Sleep time was taken for 2 hours during the day, and each subject was asked to sleep at the same time. A subjective assessment of sleep after sleep was also collected through questionnaires.

6. Analysis Method

While the subjects were taking their sleep, physiological signals were measured using a sleep polygraph, and sleep phases were analyzed using the measured signals. The determination of the sleep phase was performed by the method of Rechtschaffen and Kales (1968), an international standard.

The sleep latency and sleep efficiency were compared using different sleep stages. In addition, subjective feelings were collected through questionnaires after sleeping under given conditions, and statistical analysis was performed using t-test using the SPSS program.

7. Experimental results

7.1. Sleep latency

The elevation delay time was the time from entering the bed to sleeping, and the difference in time (minutes) from the bed to the water surface according to the sample was evaluated.

The results of the above-mentioned surface delay time experiment are shown in Table 2 and FIG.

Condition Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Example 4 Average elevation delay time (minutes) 35.80 32.10 31.90 33.50 33.10 32.85 30.90 30.50 30.05 29.55

As can be seen in Table 2 and FIG. 1, the average of the elevation delay times was shorter in the example in which the sleeping smell was included than in the control smell condition in which the smell was not used, . In addition, it can be seen that in the case of Example 4 which contains all five oils, it can be put to sleep in the earliest time.

7.2. Sleep efficiency

Sleep efficiency is the ratio of total sleep time to time on the bed, and the percentage of sleep time during the experiment was compared.

The results of the water surface efficiency are shown in Table 3 and FIG.

Condition Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Example 4 Sleep efficiency (%) 55.0 60.0 60.5 58.5 59.5 60.5 61.0 61.5 62.0 63.5

As can be seen from the above Table 3 and FIG. 2, the sleep efficiency of the example including the sleeping incense was higher than that of the control example, because the sleeping efficiency of the example including the sleeping incense was longer than that of the incense It means to lift. In addition, it can be seen that the water-surface efficiency is the highest in Example 4 containing all five oils.

7.3. Subjective evaluation

7.3.1. Degree of tension

The following Table 4 and FIG. 3 are graphs showing the degree of stress at the time of sleep compared with the normal water surface.

Condition Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Example 4 The degree of tension compared to usual (point) 0.2 0.90 0.95 0.50 0.70 0.90 1.05 1.10 0.95 1.15

As shown in Table 4 and FIG. 3, both of the comparative examples and the examples showed that they were not tensed more than usual. However, when the examples were used, they were more effective in relaxation than the control conditions, The use of Example 4 containing all of the oils proved to be most effective in relieving tension.

7.3.2. Degree of fling

Table 5 and Fig. 4 below are graphs showing the extent to which sleeping was turned on in comparison with usual.

Condition Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Example 4 The degree of repulsion compared with usual (point) -0.25 0.50 0.55 0.25 0.45 0.55 0.60 0.70 0.70 0.85

As can be seen in Table 5 and FIG. 4, the results of the comparative example were answered to be more traumatic than usual, and in the case of the example, the response was less than usual. Particularly, The results show that there is a significant difference in the degree of turnover.

7.3.3. Overall sleep level

Table 6 and Fig. 5 below are graphs showing the degree of feeling of overall sleep compared with usual.

Condition Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Example 4 Overall sleep satisfaction (point) -0.05 0.60 0.55 0.35 0.40 0.50 0.70 0.85 0.90 0.95

As can be seen in Table 6 and FIG. 5, in the comparative example, the water level was comparable to that of the usual level. However, in the case of the embodiment, the water level was better than usual. When using Example 4, overall sleep satisfaction was found to be very good.

Various formulations of cosmetics were prepared according to the following composition.

[Formulation Example 1] Nutritional lotion (milk lotion)

As shown in the following Table 7, a nutrition lotion containing the perfume composition of the examples was prepared according to a conventional method.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Squalane 5.0 Wax 4.0 Polysorbate 60 1.5 Sorbitan sesquioleate 1.5 Liquid paraffin 0.5 Caprylic / Capric Triglycerides 5.0 glycerin 3.0 Butylene glycol 3.0 Propylene glycol 3.0 Carboxyvinyl polymer 0.1 Triethanolamine 0.2 Preservative, pigment Suitable amount Purified water to 100

[Formulation Example 2] Flexible longevity (skin lotion)

The number of softening times containing the perfume composition of the examples was prepared according to a conventional method as shown in Table 8 below.

Compounding ingredient weight% The perfume composition of Example 4 1.0 glycerin 3.0 Butylene glycol 2.0 Propylene glycol 2.0 Carboxyvinyl polymer 0.1 PEG 12 nonyl phenyl ether 0.2 Polysorbate 80 0.4 ethanol 10.0 Triethanolamine 0.1 Preservative, pigment 1 Suitable amount Purified water to 100

[Formulation Example 3] Nourishing cream

Nutritional creams containing the perfume compositions of the examples were prepared according to conventional methods as shown in Table 9 below.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Polysorbate 60 1.5 Sorbitan sesquioleate 0.5 PEG60 hardened castor oil 2.0 Liquid paraffin 10 Squalane 5.0 Caprylic / Capric Triglycerides 5.0 glycerin 5.0 Butylene glycol 3.0 Propylene glycol 3.0 Triethanolamine 0.2 antiseptic Suitable amount Pigment Suitable amount Purified water to 100

[Formulation Example 4] Massage cream

A massage cream containing the perfume composition of the examples was prepared according to a conventional method as shown in Table 10 below.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Wax 10.0 Polysorbate 60 1.5 PEG 60 hardened castor oil 2.0 Sorbitan sesquioleate 0.8 Liquid paraffin 40.0 Squalane 5.0 Caprylic / capric triglyceride 4.0 glycerin 5.0 Butylene glycol 3.0 Propylene glycol 3.0 Triethanolamine 0.2 Preservative, pigment Suitable amount Purified water to 100

[Formulation Example 5] Pack

A pack containing the perfume composition of the examples as shown in the following Table 11 was prepared according to a conventional method.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Polyvinyl alcohol 13.0 Sodium carboxymethylcellulose 0.2 glycerin 5.0 Allantoin 0.1 ethanol 6.0 PEG 12 nonyl phenyl ether 0.3 Polysorbate 60 0.3 Preservative, pigment Suitable amount Purified water to 100

[Formulation Example 6]

A gel containing the perfume composition of the examples was prepared according to a conventional method as shown in Table 12 below.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Ethylenediamine sodium acetate 0.05 glycerin 5.0 Carboxyvinyl polymer 0.3 ethanol 5.0 PEG 60 hardened castor oil 0.5 Triethanolamine 0.3 Preservative, pigment Suitable amount Purified water to 100

[Formulation Example 7] Water-in-oil type emulsion type makeup cosmetic

As shown in Table 13 below, a water-in-oil type emulsion type makeup cosmetic containing the perfume composition of the examples was prepared according to a conventional method.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Butylene glycol 10 Salt 1.5 Ozokerite 2.0 Dicaprylyl carbonate 20 Sorbitan isostearate 2.5 Cetyl dimethicone copolyol 2.0 Polymethyl methacrylate 3.0 Iron oxide 1.5 Titanium oxide 12.0 Talc (size: 3.06 micro) 5.0 Preservative, pigment Suitable amount Purified water to 100

[Formulation Example 8] Twin cake, powder cosmetic

Tween cake and powder cosmetic compositions containing the perfume compositions of the examples were prepared according to the conventional method as shown in Table 14 below.

Compounding ingredient weight% The perfume composition of Example 4 1.0 Nylon Powder 5.0 Modified starch 3.0 Titanium dioxide 3.0 Mica 25.0 Squalene 0.5 Dimethicone 0.8 Preservative, pigment Suitable amount Silicone-treated talc to 100

Those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the same is by way of illustration and example only and is not to be construed as limiting the scope of the present invention. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

Claims (6)

Eucalyptus leaf oil, cedarwood oil, phenethyl alcohol, methyl dihydro jasmonate, and linalool. The perfume composition of claim 1, wherein the composition comprises eucalyptus leaf oil, cedarwood oil, phenethyl alcohol, methyl dihydro jasmonate, and linalool. The composition according to claim 2, which comprises 0.1 to 20% by weight of eucalyptus leaf oil, 0.1 to 20% by weight of cedarwood oil, 0.5 to 50% by weight of phenethyl alcohol, 10 to 50% by weight of methyl dihydro jasmonate, And 10 to 30% by weight of linolul. The perfume composition of claim 1, wherein said composition is for inducing sleep. A composition for external application for skin comprising the perfume composition according to any one of claims 1 to 4. 6. The composition according to claim 5, wherein the composition for external application for skin comprises the fragrance composition in an amount of 0.01 to 30% by weight based on the total weight of the composition.

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